Rattus norvegicus

0 known processes

Fanca

Fanconi anemia, complementation group A

Fanca biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.052
transcription dna templated GO:0006351 377 0.044
protein complex subunit organization GO:0071822 302 0.043
catabolic process GO:0009056 351 0.043
brain development GO:0007420 247 0.043
regulation of protein metabolic process GO:0051246 289 0.039
negative regulation of metabolic process GO:0009892 331 0.038
response to oxygen levels GO:0070482 265 0.038
head development GO:0060322 247 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.035
intracellular signal transduction GO:0035556 314 0.035
protein complex assembly GO:0006461 263 0.035
cell cell signaling GO:0007267 335 0.035
regulation of rna biosynthetic process GO:2001141 381 0.033
rna metabolic process GO:0016070 406 0.033
cellular component assembly GO:0022607 360 0.033
cellular amine metabolic process GO:0044106 38 0.032
anatomical structure morphogenesis GO:0009653 298 0.031
organic acid metabolic process GO:0006082 292 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
organic substance catabolic process GO:1901575 316 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.028
nucleic acid templated transcription GO:0097659 379 0.028
regulation of rna metabolic process GO:0051252 391 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
cellular component biogenesis GO:0044085 368 0.027
protein complex biogenesis GO:0070271 263 0.026
regulation of cell proliferation GO:0042127 359 0.026
neuron development GO:0048666 286 0.026
single organism catabolic process GO:0044712 283 0.026
response to peptide GO:1901652 292 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
cellular catabolic process GO:0044248 295 0.024
cell part morphogenesis GO:0032990 123 0.024
cation transport GO:0006812 382 0.024
oxoacid metabolic process GO:0043436 290 0.024
response to decreased oxygen levels GO:0036293 237 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
cytoskeleton organization GO:0007010 111 0.024
cellular response to stress GO:0033554 269 0.023
regulation of transcription dna templated GO:0006355 374 0.023
signal release GO:0023061 145 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
cell projection organization GO:0030030 302 0.023
regulation of peptide transport GO:0090087 87 0.023
macromolecular complex assembly GO:0065003 273 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
chemical homeostasis GO:0048878 292 0.022
regulation of cell differentiation GO:0045595 320 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
positive regulation of immune system process GO:0002684 90 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
peptide secretion GO:0002790 86 0.021
regulation of molecular function GO:0065009 398 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
cellular ketone metabolic process GO:0042180 51 0.021
central nervous system development GO:0007417 311 0.021
response to extracellular stimulus GO:0009991 380 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of peptide hormone secretion GO:0090276 80 0.020
neuron projection development GO:0031175 273 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
small gtpase mediated signal transduction GO:0007264 36 0.019
hormone secretion GO:0046879 115 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
amine metabolic process GO:0009308 38 0.019
positive regulation of transport GO:0051050 245 0.019
rna biosynthetic process GO:0032774 380 0.019
single organism biosynthetic process GO:0044711 342 0.019
secretion by cell GO:0032940 248 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
metal ion homeostasis GO:0055065 186 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
immune system process GO:0002376 204 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
ras protein signal transduction GO:0007265 29 0.018
reproductive process GO:0022414 372 0.017
regulation of apoptotic process GO:0042981 335 0.017
cell projection morphogenesis GO:0048858 123 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
aging GO:0007568 241 0.017
dna integrity checkpoint GO:0031570 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
nucleoside metabolic process GO:0009116 179 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of signal transduction GO:0009966 318 0.017
organelle organization GO:0006996 266 0.016
anterior posterior pattern specification GO:0009952 1 0.016
single organism reproductive process GO:0044702 297 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
cellular chemical homeostasis GO:0055082 247 0.016
positive regulation of signaling GO:0023056 270 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of peptide secretion GO:0002791 82 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
regulation of cell development GO:0060284 263 0.016
regulation of immune system process GO:0002682 123 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
microtubule organizing center organization GO:0031023 1 0.015
monosaccharide metabolic process GO:0005996 61 0.015
regulation of cellular localization GO:0060341 263 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
secretion GO:0046903 307 0.015
protein phosphorylation GO:0006468 345 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
axis specification GO:0009798 4 0.015
regulation of secretion GO:0051046 224 0.015
cellular cation homeostasis GO:0030003 180 0.015
programmed cell death GO:0012501 392 0.014
cell activation GO:0001775 97 0.014
regulation of secretion by cell GO:1903530 208 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of gene expression GO:0010628 244 0.014
cation transmembrane transport GO:0098655 263 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
regulation of leukocyte activation GO:0002694 45 0.014
amide transport GO:0042886 105 0.014
response to ethanol GO:0045471 162 0.014
negative regulation of cell development GO:0010721 82 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cellular homeostasis GO:0019725 252 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
regulation of phosphorylation GO:0042325 248 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
epithelium development GO:0060429 96 0.014
cellular protein complex assembly GO:0043623 44 0.014
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cell cycle GO:0007049 101 0.013
single organism organelle organization GO:1902589 180 0.013
centrosome organization GO:0051297 1 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
response to oxidative stress GO:0006979 186 0.013
response to hypoxia GO:0001666 231 0.013
cellular component morphogenesis GO:0032989 155 0.013
metal ion transport GO:0030001 289 0.013
proteolysis GO:0006508 175 0.013
anion transport GO:0006820 178 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
response to nutrient levels GO:0031667 370 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of neurogenesis GO:0050767 247 0.013
positive regulation of developmental process GO:0051094 283 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
negative regulation of nervous system development GO:0051961 79 0.012
actin cytoskeleton organization GO:0030036 73 0.012
regulation of metal ion transport GO:0010959 118 0.012
peptide transport GO:0015833 97 0.012
purine containing compound catabolic process GO:0072523 138 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
negative regulation of developmental process GO:0051093 125 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
macromolecule localization GO:0033036 252 0.012
response to growth factor GO:0070848 189 0.012
gamete generation GO:0007276 124 0.012
reproduction GO:0000003 245 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
chromosome segregation GO:0007059 2 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
positive regulation of cell communication GO:0010647 271 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
axon development GO:0061564 96 0.011
hormone transport GO:0009914 121 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
peptide hormone secretion GO:0030072 84 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
regulation of organelle organization GO:0033043 80 0.011
positive regulation of cell activation GO:0050867 34 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of hormone levels GO:0010817 187 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of insulin secretion GO:0050796 65 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
action potential GO:0001508 54 0.011
calcium ion homeostasis GO:0055074 162 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
nucleotide metabolic process GO:0009117 279 0.011
cell cycle checkpoint GO:0000075 2 0.011
centrosome cycle GO:0007098 1 0.011
lipid metabolic process GO:0006629 283 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of cellular component organization GO:0051128 368 0.011
regulation of neuron projection development GO:0010975 161 0.011
regulation of cell projection organization GO:0031344 175 0.011
multicellular organism growth GO:0035264 1 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
response to ketone GO:1901654 182 0.011
rhythmic process GO:0048511 156 0.011
positive regulation of molecular function GO:0044093 230 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
response to wounding GO:0009611 254 0.011
response to hydrogen peroxide GO:0042542 89 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
negative regulation of molecular function GO:0044092 133 0.010
cellular ion homeostasis GO:0006873 184 0.010
negative regulation of gene expression GO:0010629 199 0.010
regulation of catabolic process GO:0009894 113 0.010
lymphocyte activation GO:0046649 43 0.010
rna localization GO:0006403 4 0.010
cell morphogenesis GO:0000902 142 0.010
embryonic axis specification GO:0000578 1 0.010
neuron fate commitment GO:0048663 4 0.010
embryonic pattern specification GO:0009880 1 0.010
regulation of hormone secretion GO:0046883 106 0.010
purine containing compound metabolic process GO:0072521 253 0.010
small molecule catabolic process GO:0044282 59 0.010
positive regulation of secretion GO:0051047 140 0.010
dna damage checkpoint GO:0000077 2 0.010
positive regulation of cell development GO:0010720 176 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010

Fanca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010