Rattus norvegicus

34 known processes

Fasn

fatty acid synthase

Fasn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acyl coa metabolic process GO:0006637 28 0.997
lipid biosynthetic process GO:0008610 128 0.990
small molecule biosynthetic process GO:0044283 124 0.973
lipid metabolic process GO:0006629 283 0.962
cellular lipid metabolic process GO:0044255 208 0.945
cofactor metabolic process GO:0051186 95 0.928
coenzyme metabolic process GO:0006732 86 0.913
carboxylic acid biosynthetic process GO:0046394 83 0.887
organic acid biosynthetic process GO:0016053 83 0.847
monocarboxylic acid biosynthetic process GO:0072330 48 0.804
organic acid metabolic process GO:0006082 292 0.787
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.767
sterol biosynthetic process GO:0016126 10 0.748
single organism biosynthetic process GO:0044711 342 0.733
sulfur compound metabolic process GO:0006790 70 0.733
fatty acid metabolic process GO:0006631 99 0.695
fatty acid biosynthetic process GO:0006633 33 0.632
acetyl coa metabolic process GO:0006084 17 0.615
cholesterol biosynthetic process GO:0006695 10 0.597
male mating behavior GO:0060179 3 0.586
sterol metabolic process GO:0016125 18 0.585
oxoacid metabolic process GO:0043436 290 0.578
positive regulation of triglyceride metabolic process GO:0090208 4 0.466
regulation of lipid metabolic process GO:0019216 68 0.381
monocarboxylic acid metabolic process GO:0032787 152 0.353
response to sucrose GO:0009744 10 0.350
thioester metabolic process GO:0035383 28 0.345
steroid biosynthetic process GO:0006694 48 0.317
alcohol metabolic process GO:0006066 77 0.293
response to carbohydrate GO:0009743 183 0.290
long chain fatty acid metabolic process GO:0001676 32 0.240
regulation of cholesterol biosynthetic process GO:0045540 4 0.235
carboxylic acid metabolic process GO:0019752 289 0.231
organic hydroxy compound biosynthetic process GO:1901617 51 0.227
sexual reproduction GO:0019953 148 0.219
cholesterol metabolic process GO:0008203 17 0.217
regulation of triglyceride biosynthetic process GO:0010866 4 0.203
long chain fatty acid biosynthetic process GO:0042759 5 0.195
response to disaccharide GO:0034285 10 0.187
acetate metabolic process GO:0006083 2 0.186
alcohol biosynthetic process GO:0046165 38 0.185
regulation of nucleic acid templated transcription GO:1903506 380 0.183
regulation of lipid biosynthetic process GO:0046890 38 0.163
cellular response to oxygen containing compound GO:1901701 386 0.153
organic hydroxy compound metabolic process GO:1901615 115 0.135
steroid metabolic process GO:0008202 73 0.121
tricarboxylic acid metabolic process GO:0072350 10 0.112
neutral lipid biosynthetic process GO:0046460 7 0.103
vesicle mediated transport GO:0016192 181 0.091
negative regulation of nucleic acid templated transcription GO:1903507 117 0.086
myelination GO:0042552 39 0.086
multicellular organism reproduction GO:0032504 233 0.083
regulation of cholesterol metabolic process GO:0090181 5 0.081
metanephric tubule development GO:0072170 4 0.078
organophosphate biosynthetic process GO:0090407 143 0.076
reproduction GO:0000003 245 0.072
neuronal action potential GO:0019228 35 0.068
multi organism reproductive process GO:0044703 262 0.066
response to isolation stress GO:0035900 2 0.065
cellular response to nitrogen compound GO:1901699 210 0.065
positive regulation of cellular biosynthetic process GO:0031328 295 0.064
glycerolipid metabolic process GO:0046486 67 0.063
ensheathment of neurons GO:0007272 40 0.063
arachidonic acid metabolic process GO:0019369 20 0.062
secretion GO:0046903 307 0.060
negative regulation of rna metabolic process GO:0051253 123 0.060
nicotinamide nucleotide metabolic process GO:0046496 28 0.058
axon ensheathment GO:0008366 40 0.057
icosanoid metabolic process GO:0006690 38 0.056
regulation of cellular component organization GO:0051128 368 0.055
cytoskeleton dependent cytokinesis GO:0061640 2 0.052
acylglycerol biosynthetic process GO:0046463 7 0.050
transcription dna templated GO:0006351 377 0.048
nucleic acid templated transcription GO:0097659 379 0.048
multicellular organismal signaling GO:0035637 44 0.047
action potential GO:0001508 54 0.047
rna metabolic process GO:0016070 406 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.044
negative regulation of transcription dna templated GO:0045892 116 0.043
reproductive process GO:0022414 372 0.043
regulation of membrane potential GO:0042391 110 0.042
heart process GO:0003015 57 0.042
response to extracellular stimulus GO:0009991 380 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
aging GO:0007568 241 0.041
single organism carbohydrate catabolic process GO:0044724 40 0.041
regulation of secretion GO:0051046 224 0.040
heart contraction GO:0060047 57 0.040
phospholipid metabolic process GO:0006644 61 0.040
intracellular transport GO:0046907 185 0.038
response to insulin GO:0032868 133 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
ribose phosphate metabolic process GO:0019693 235 0.036
response to ethanol GO:0045471 162 0.036
response to nutrient levels GO:0031667 370 0.036
behavior GO:0007610 205 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
regulation of hormone levels GO:0010817 187 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
regulation of transcription dna templated GO:0006355 374 0.034
homeostatic process GO:0042592 331 0.034
negative regulation of hormone secretion GO:0046888 46 0.033
oxidation reduction process GO:0055114 304 0.033
response to vitamin GO:0033273 131 0.033
transmembrane transport GO:0055085 412 0.033
regulation of hormone secretion GO:0046883 106 0.032
transmission of nerve impulse GO:0019226 42 0.032
regulation of cellular localization GO:0060341 263 0.032
response to peptide GO:1901652 292 0.032
multi multicellular organism process GO:0044706 138 0.031
citrate metabolic process GO:0006101 3 0.031
rna biosynthetic process GO:0032774 380 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
positive regulation of lipid biosynthetic process GO:0046889 25 0.030
cellular response to nutrient levels GO:0031669 60 0.030
secretion by cell GO:0032940 248 0.030
organophosphate metabolic process GO:0019637 370 0.030
triglyceride biosynthetic process GO:0019432 7 0.029
negative regulation of gene expression GO:0010629 199 0.029
single organism intracellular transport GO:1902582 166 0.029
regulation of fatty acid metabolic process GO:0019217 18 0.029
response to purine containing compound GO:0014074 126 0.028
regulation of catabolic process GO:0009894 113 0.028
carboxylic acid transport GO:0046942 115 0.028
pentose metabolic process GO:0019321 8 0.028
response to acid chemical GO:0001101 222 0.028
cellular response to lipid GO:0071396 201 0.027
regulation of peptide transport GO:0090087 87 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
nucleotide metabolic process GO:0009117 279 0.026
regulation of cell proliferation GO:0042127 359 0.026
regulation of peptide hormone secretion GO:0090276 80 0.026
cellular response to acid chemical GO:0071229 75 0.025
regulation of organelle organization GO:0033043 80 0.025
hormone transport GO:0009914 121 0.025
blood circulation GO:0008015 183 0.025
regulation of alcohol biosynthetic process GO:1902930 12 0.025
response to lead ion GO:0010288 33 0.024
cellular protein localization GO:0034613 122 0.024
pyridine containing compound metabolic process GO:0072524 32 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
rhythmic process GO:0048511 156 0.023
hormone metabolic process GO:0042445 69 0.023
peptide hormone secretion GO:0030072 84 0.023
protein transport GO:0015031 132 0.023
hormone biosynthetic process GO:0042446 25 0.023
gamete generation GO:0007276 124 0.023
single organism reproductive process GO:0044702 297 0.023
hexose catabolic process GO:0019320 10 0.022
negative regulation of metabolic process GO:0009892 331 0.022
monosaccharide catabolic process GO:0046365 10 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
circadian rhythm GO:0007623 88 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
neurological system process GO:0050877 219 0.021
cell projection organization GO:0030030 302 0.021
unsaturated fatty acid biosynthetic process GO:0006636 21 0.021
cellular response to fatty acid GO:0071398 29 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
single organism organelle organization GO:1902589 180 0.021
regulation of peptide secretion GO:0002791 82 0.021
regulation of rna metabolic process GO:0051252 391 0.021
response to nutrient GO:0007584 248 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
response to food GO:0032094 27 0.021
multicellular organism growth GO:0035264 1 0.020
mitotic cell cycle process GO:1903047 35 0.020
ras protein signal transduction GO:0007265 29 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
chemical homeostasis GO:0048878 292 0.020
unsaturated fatty acid metabolic process GO:0033559 39 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
positive regulation of organelle organization GO:0010638 48 0.019
pentose phosphate shunt GO:0006098 8 0.019
triglyceride metabolic process GO:0006641 21 0.019
peptide secretion GO:0002790 86 0.019
regulation of steroid metabolic process GO:0019218 25 0.019
peptide transport GO:0015833 97 0.019
neutral lipid metabolic process GO:0006638 21 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
sterol homeostasis GO:0055092 3 0.019
cell cell signaling GO:0007267 335 0.018
nuclear import GO:0051170 35 0.018
lung development GO:0030324 43 0.018
signal release GO:0023061 145 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
regulation of secretion by cell GO:1903530 208 0.018
negative regulation of cell communication GO:0010648 158 0.018
intracellular protein transport GO:0006886 79 0.018
positive regulation of cellular component organization GO:0051130 200 0.017
response to retinoic acid GO:0032526 63 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
catabolic process GO:0009056 351 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
response to radiation GO:0009314 137 0.017
amine metabolic process GO:0009308 38 0.017
carbohydrate homeostasis GO:0033500 75 0.017
male gamete generation GO:0048232 99 0.017
response to decreased oxygen levels GO:0036293 237 0.016
endocytosis GO:0006897 84 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
anion transport GO:0006820 178 0.016
nitrogen compound transport GO:0071705 229 0.016
heart morphogenesis GO:0003007 3 0.016
cell cycle process GO:0022402 57 0.016
response to ketone GO:1901654 182 0.016
single organism nuclear import GO:1902593 35 0.016
regulation of neuron projection development GO:0010975 161 0.016
short chain fatty acid metabolic process GO:0046459 3 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
negative regulation of secretion GO:0051048 82 0.016
organelle organization GO:0006996 266 0.015
response to camp GO:0051591 91 0.015
glucose homeostasis GO:0042593 75 0.015
nuclear transport GO:0051169 49 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
spermatogenesis GO:0007283 99 0.015
kidney epithelium development GO:0072073 19 0.015
secondary metabolic process GO:0019748 15 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
positive regulation of skeletal muscle tissue development GO:0048643 4 0.015
circulatory system development GO:0072359 134 0.015
single organism catabolic process GO:0044712 283 0.015
positive regulation of lipid metabolic process GO:0045834 33 0.015
positive regulation of gene expression GO:0010628 244 0.014
response to monosaccharide GO:0034284 159 0.014
purine containing compound metabolic process GO:0072521 253 0.014
liver development GO:0001889 90 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of insulin secretion GO:0050796 65 0.014
cellular ketone metabolic process GO:0042180 51 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
ion transmembrane transport GO:0034220 365 0.014
regulation of protein metabolic process GO:0051246 289 0.014
insulin receptor signaling pathway GO:0008286 24 0.014
brain development GO:0007420 247 0.014
regulation of cell development GO:0060284 263 0.014
glycerol 3 phosphate metabolic process GO:0006072 2 0.014
protein complex subunit organization GO:0071822 302 0.014
cellular component biogenesis GO:0044085 368 0.014
response to corticosteroid GO:0031960 235 0.014
cellular macromolecule localization GO:0070727 122 0.013
cellular amine metabolic process GO:0044106 38 0.013
pyridine nucleotide metabolic process GO:0019362 28 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
organic substance catabolic process GO:1901575 316 0.013
regulation of developmental growth GO:0048638 45 0.013
cellular response to stress GO:0033554 269 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
organic anion transport GO:0015711 132 0.013
cellular response to starvation GO:0009267 27 0.013
cell morphogenesis GO:0000902 142 0.013
protein targeting GO:0006605 61 0.013
central nervous system development GO:0007417 311 0.013
cell cycle GO:0007049 101 0.012
single organism cellular localization GO:1902580 102 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
response to starvation GO:0042594 59 0.012
regulation of signal transduction GO:0009966 318 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
neuron projection development GO:0031175 273 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
organic acid transport GO:0015849 116 0.012
cardiac chamber development GO:0003205 1 0.012
cytoskeleton organization GO:0007010 111 0.012
establishment of protein localization GO:0045184 141 0.012
sensory perception GO:0007600 101 0.012
nucleotide biosynthetic process GO:0009165 98 0.011
body fluid secretion GO:0007589 41 0.011
axis specification GO:0009798 4 0.011
response to corticosterone GO:0051412 40 0.011
negative regulation of peptide hormone secretion GO:0090278 30 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to vitamin a GO:0033189 36 0.011
reproductive behavior GO:0019098 10 0.011
renal system development GO:0072001 67 0.011
protein import into nucleus GO:0006606 35 0.011
response to metal ion GO:0010038 253 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
positive regulation of developmental process GO:0051094 283 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
mating GO:0007618 22 0.011
positive regulation of cell development GO:0010720 176 0.011
response to glucose GO:0009749 136 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
regulation of heart rate GO:0002027 16 0.011
cellular chemical homeostasis GO:0055082 247 0.011
developmental growth GO:0048589 100 0.011
gonad development GO:0008406 104 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
protein complex biogenesis GO:0070271 263 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to cholesterol GO:0070723 13 0.011
hexose metabolic process GO:0019318 58 0.011
response to inorganic substance GO:0010035 377 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
circulatory system process GO:0003013 183 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
regulation of growth GO:0040008 105 0.010
regulation of transmembrane transport GO:0034762 122 0.010
mitochondrion organization GO:0007005 35 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
regulation of anatomical structure size GO:0090066 135 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
microtubule based process GO:0007017 36 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
regulation of blood circulation GO:1903522 110 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
development of primary sexual characteristics GO:0045137 107 0.010

Fasn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011