Rattus norvegicus

14 known processes

Fbln1

fibulin 1

Fbln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.187
cellular component biogenesis GO:0044085 368 0.163
reproductive process GO:0022414 372 0.161
cellular component assembly GO:0022607 360 0.151
glomerulus development GO:0032835 10 0.126
rna metabolic process GO:0016070 406 0.124
renal system development GO:0072001 67 0.117
female pregnancy GO:0007565 122 0.109
oxoacid metabolic process GO:0043436 290 0.102
regulation of rna biosynthetic process GO:2001141 381 0.099
response to corticosteroid GO:0031960 235 0.099
protein complex biogenesis GO:0070271 263 0.096
organ regeneration GO:0031100 101 0.095
regulation of rna metabolic process GO:0051252 391 0.092
anatomical structure morphogenesis GO:0009653 298 0.085
rna biosynthetic process GO:0032774 380 0.085
nucleic acid templated transcription GO:0097659 379 0.080
response to biotic stimulus GO:0009607 226 0.078
protein homooligomerization GO:0051260 91 0.078
transcription from rna polymerase ii promoter GO:0006366 252 0.078
kidney development GO:0001822 67 0.074
macromolecular complex assembly GO:0065003 273 0.073
single organism reproductive process GO:0044702 297 0.072
glomerulus vasculature development GO:0072012 6 0.069
protein complex assembly GO:0006461 263 0.068
regulation of multicellular organismal development GO:2000026 376 0.067
protein oligomerization GO:0051259 191 0.064
regeneration GO:0031099 163 0.061
response to hypoxia GO:0001666 231 0.059
response to other organism GO:0051707 220 0.057
multi organism reproductive process GO:0044703 262 0.053
regulation of transcription dna templated GO:0006355 374 0.052
cell projection organization GO:0030030 302 0.051
response to molecule of bacterial origin GO:0002237 194 0.050
regulation of protein metabolic process GO:0051246 289 0.049
aging GO:0007568 241 0.049
protein complex subunit organization GO:0071822 302 0.048
regulation of nucleic acid templated transcription GO:1903506 380 0.048
multi multicellular organism process GO:0044706 138 0.047
regulation of signal transduction GO:0009966 318 0.046
neurological system process GO:0050877 219 0.044
multicellular organism reproduction GO:0032504 233 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
kidney vasculature development GO:0061440 6 0.043
reproduction GO:0000003 245 0.042
cell motility GO:0048870 202 0.042
enzyme linked receptor protein signaling pathway GO:0007167 116 0.041
tissue remodeling GO:0048771 40 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.041
response to bacterium GO:0009617 200 0.041
response to growth factor GO:0070848 189 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
response to decreased oxygen levels GO:0036293 237 0.040
regulation of cellular component organization GO:0051128 368 0.040
cellular response to stress GO:0033554 269 0.037
amine metabolic process GO:0009308 38 0.036
response to oxygen levels GO:0070482 265 0.036
negative regulation of gene expression GO:0010629 199 0.036
regulation of cell growth GO:0001558 85 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.035
chemical homeostasis GO:0048878 292 0.034
response to lipopolysaccharide GO:0032496 191 0.034
wound healing GO:0042060 122 0.034
positive regulation of cell death GO:0010942 184 0.034
cellular response to hormone stimulus GO:0032870 247 0.033
circulatory system development GO:0072359 134 0.033
positive regulation of developmental process GO:0051094 283 0.033
behavior GO:0007610 205 0.033
negative regulation of metabolic process GO:0009892 331 0.033
response to external biotic stimulus GO:0043207 221 0.033
response to nutrient GO:0007584 248 0.033
cell migration GO:0016477 197 0.032
negative regulation of response to stimulus GO:0048585 155 0.032
response to glucocorticoid GO:0051384 223 0.032
homeostatic process GO:0042592 331 0.032
response to extracellular stimulus GO:0009991 380 0.031
cardiovascular system development GO:0072358 134 0.031
regulation of molecular function GO:0065009 398 0.031
response to mechanical stimulus GO:0009612 134 0.031
intracellular signal transduction GO:0035556 314 0.031
rhythmic process GO:0048511 156 0.031
cellular amine metabolic process GO:0044106 38 0.031
apoptotic process GO:0006915 381 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
cellular response to endogenous stimulus GO:0071495 377 0.030
developmental process involved in reproduction GO:0003006 159 0.030
organ morphogenesis GO:0009887 75 0.030
gastrulation GO:0007369 2 0.030
regulation of body fluid levels GO:0050878 90 0.030
cell growth GO:0016049 104 0.029
cellular ketone metabolic process GO:0042180 51 0.029
reproductive structure development GO:0048608 128 0.029
regulation of membrane potential GO:0042391 110 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.029
multicellular organismal reproductive process GO:0048609 233 0.028
response to glucose GO:0009749 136 0.028
regulation of canonical wnt signaling pathway GO:0060828 4 0.028
response to acid chemical GO:0001101 222 0.027
defense response GO:0006952 194 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
response to monosaccharide GO:0034284 159 0.027
response to estrogen GO:0043627 232 0.027
response to ketone GO:1901654 182 0.027
programmed cell death GO:0012501 392 0.027
response to peptide hormone GO:0043434 278 0.027
organic acid metabolic process GO:0006082 292 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
regulation of ossification GO:0030278 32 0.026
action potential GO:0001508 54 0.026
head development GO:0060322 247 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of cell proliferation GO:0042127 359 0.025
proteolysis GO:0006508 175 0.025
protein phosphorylation GO:0006468 345 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
response to peptide GO:1901652 292 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
cellular response to external stimulus GO:0071496 118 0.024
urogenital system development GO:0001655 78 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
positive regulation of gene expression GO:0010628 244 0.024
positive regulation of phosphorylation GO:0042327 177 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of hormone levels GO:0010817 187 0.023
tissue development GO:0009888 252 0.023
response to cytokine GO:0034097 215 0.023
positive regulation of signaling GO:0023056 270 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
cell cell signaling GO:0007267 335 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of programmed cell death GO:0043067 341 0.022
peptidyl amino acid modification GO:0018193 126 0.021
regulation of cellular component movement GO:0051270 150 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
neuron projection development GO:0031175 273 0.021
connective tissue development GO:0061448 33 0.021
response to nutrient levels GO:0031667 370 0.021
response to wounding GO:0009611 254 0.021
ras protein signal transduction GO:0007265 29 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
negative regulation of cell death GO:0060548 229 0.021
transmembrane transport GO:0055085 412 0.020
neuron differentiation GO:0030182 368 0.020
muscle structure development GO:0061061 87 0.020
regulation of neurogenesis GO:0050767 247 0.020
response to hexose GO:0009746 144 0.020
vasculature development GO:0001944 70 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cation transport GO:0006812 382 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
response to purine containing compound GO:0014074 126 0.019
myelination GO:0042552 39 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
protein maturation GO:0051604 68 0.019
regulation of phosphorylation GO:0042325 248 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of catalytic activity GO:0050790 304 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of cell differentiation GO:0045595 320 0.019
embryonic skeletal system development GO:0048706 3 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
response to insulin GO:0032868 133 0.018
cell adhesion GO:0007155 110 0.018
cell part morphogenesis GO:0032990 123 0.018
regulation of response to stress GO:0080134 126 0.018
response to activity GO:0014823 73 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
organic substance catabolic process GO:1901575 316 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
catabolic process GO:0009056 351 0.018
central nervous system development GO:0007417 311 0.017
angiogenesis GO:0001525 53 0.017
positive regulation of transport GO:0051050 245 0.017
synaptic transmission GO:0007268 235 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
protein localization GO:0008104 191 0.017
response to carbohydrate GO:0009743 183 0.017
negative regulation of signaling GO:0023057 157 0.017
taxis GO:0042330 67 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
chemotaxis GO:0006935 66 0.016
transmission of nerve impulse GO:0019226 42 0.016
regulation of nervous system development GO:0051960 264 0.016
cellular hormone metabolic process GO:0034754 49 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
ossification GO:0001503 70 0.016
regulation of system process GO:0044057 208 0.016
response to estradiol GO:0032355 164 0.016
cardiac chamber development GO:0003205 1 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
gland development GO:0048732 155 0.016
sensory perception GO:0007600 101 0.016
hormone metabolic process GO:0042445 69 0.016
regulation of locomotion GO:0040012 148 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
regulation of blood circulation GO:1903522 110 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
response to interleukin 1 GO:0070555 55 0.015
regulation of apoptotic process GO:0042981 335 0.015
regulation of transferase activity GO:0051338 123 0.015
multicellular organismal signaling GO:0035637 44 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
oxidation reduction process GO:0055114 304 0.015
regulation of fat cell differentiation GO:0045598 3 0.015
anterior posterior pattern specification GO:0009952 1 0.015
cellular ion homeostasis GO:0006873 184 0.015
growth GO:0040007 165 0.015
regulation of growth GO:0040008 105 0.015
sexual reproduction GO:0019953 148 0.015
inflammatory response GO:0006954 150 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
epithelial cell proliferation GO:0050673 54 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.015
regulation of immune system process GO:0002682 123 0.015
anion transport GO:0006820 178 0.015
neuronal action potential GO:0019228 35 0.014
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of signal transduction GO:0009968 83 0.014
endocrine system development GO:0035270 30 0.014
neuron development GO:0048666 286 0.014
odontogenesis GO:0042476 32 0.014
gliogenesis GO:0042063 93 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
negative regulation of protein maturation GO:1903318 47 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
mesoderm development GO:0007498 2 0.014
cellular chemical homeostasis GO:0055082 247 0.014
regulation of hydrolase activity GO:0051336 143 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
metal ion transport GO:0030001 289 0.014
endocytosis GO:0006897 84 0.014
negative regulation of developmental process GO:0051093 125 0.014
axon ensheathment GO:0008366 40 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
cellular response to alcohol GO:0097306 87 0.014
response to ethanol GO:0045471 162 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
peptide cross linking GO:0018149 1 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
axis specification GO:0009798 4 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
response to inorganic substance GO:0010035 377 0.013
calcium ion transport GO:0006816 131 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of mapk cascade GO:0043408 116 0.013
locomotion GO:0040011 237 0.013
positive regulation of response to external stimulus GO:0032103 51 0.013
protein processing GO:0016485 68 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
immune system process GO:0002376 204 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of cellular localization GO:0060341 263 0.013
metal ion homeostasis GO:0055065 186 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
nucleotide metabolic process GO:0009117 279 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
organic anion transport GO:0015711 132 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of response to wounding GO:1903034 69 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
response to organophosphorus GO:0046683 102 0.012
regulation of synaptic transmission GO:0050804 141 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cellular component movement GO:0006928 248 0.012
response to toxic substance GO:0009636 133 0.012
positive regulation of nervous system development GO:0051962 178 0.012
ensheathment of neurons GO:0007272 40 0.012
gamete generation GO:0007276 124 0.012
regulation of protein processing GO:0070613 50 0.012
cellular response to starvation GO:0009267 27 0.012
nitrogen compound transport GO:0071705 229 0.012
divalent inorganic cation transport GO:0072511 134 0.012
gonad development GO:0008406 104 0.012
ion homeostasis GO:0050801 212 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
regulation of platelet activation GO:0010543 2 0.012
cation transmembrane transport GO:0098655 263 0.011
maternal process involved in female pregnancy GO:0060135 38 0.011
regulation of leukocyte migration GO:0002685 24 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of response to external stimulus GO:0032101 106 0.011
brain development GO:0007420 247 0.011
blood circulation GO:0008015 183 0.011
female sex differentiation GO:0046660 59 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
ovulation cycle GO:0042698 67 0.011
osteoblast differentiation GO:0001649 26 0.011
cellular component morphogenesis GO:0032989 155 0.011
axon development GO:0061564 96 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
blood vessel development GO:0001568 69 0.011
reproductive system development GO:0061458 128 0.011
cellular cation homeostasis GO:0030003 180 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
regulation of behavior GO:0050795 61 0.011
regulation of osteoblast differentiation GO:0045667 14 0.011
sex differentiation GO:0007548 113 0.011
respiratory system development GO:0060541 45 0.011
muscle system process GO:0003012 115 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
cellular response to interleukin 1 GO:0071347 37 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of secretion GO:0051046 224 0.010
positive regulation of molecular function GO:0044093 230 0.010
skeletal system development GO:0001501 41 0.010
renal filtration GO:0097205 10 0.010
protein transport GO:0015031 132 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010
vesicle mediated transport GO:0016192 181 0.010
positive regulation of immune system process GO:0002684 90 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
nucleoside metabolic process GO:0009116 179 0.010
single organismal cell cell adhesion GO:0016337 42 0.010
glial cell differentiation GO:0010001 65 0.010
peptide transport GO:0015833 97 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
secretion by cell GO:0032940 248 0.010
regulation of protein kinase activity GO:0045859 105 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010

Fbln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
muscular disease DOID:0080000 0 0.019
myopathy DOID:423 0 0.014