|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.817
|
Human |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.810
|
Human Mouse Rat Fly |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.794
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.761
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.687
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.685
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.638
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.621
|
Zebrafish |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.599
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.591
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.583
|
Zebrafish Mouse Rat Fly |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.578
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.572
|
Human Mouse Rat Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.558
|
Human Zebrafish Mouse Rat Worm |
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.557
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.540
|
Human Mouse Rat Fly |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.532
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.531
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.495
|
Human Mouse Rat Fly |
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.488
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.472
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.470
|
Mouse |
|
|
tube development
|
GO:0035295 |
89 |
0.463
|
Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.451
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.433
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.427
|
Mouse |
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.425
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.419
|
Mouse |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.407
|
Human Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.401
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.398
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.395
|
Human Mouse Rat Fly |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.393
|
Human Mouse Rat Fly |
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.377
|
Human Fly |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.377
|
Human Mouse Rat Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.377
|
|
|
|
blood vessel development
|
GO:0001568 |
69 |
0.375
|
Mouse |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.374
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.371
|
Human Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.368
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.367
|
Human Mouse Rat Fly |
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.367
|
Zebrafish Mouse Fly |
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
2 |
0.362
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.357
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.356
|
Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.355
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.354
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.347
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.347
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.338
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.334
|
Rat Worm Fly |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.330
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.326
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.318
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.314
|
Mouse |
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.308
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.305
|
Human Mouse Rat Fly |
|
|
cell migration
|
GO:0016477 |
197 |
0.296
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.295
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.294
|
Mouse |
|
|
gland development
|
GO:0048732 |
155 |
0.293
|
Zebrafish Mouse Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.288
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.287
|
Human Mouse Rat Fly |
|
|
response to other organism
|
GO:0051707 |
220 |
0.285
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
110 |
0.285
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.283
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.281
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.280
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.280
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.277
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
2 |
0.275
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.269
|
Worm Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.268
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.268
|
Human Zebrafish Mouse Rat Worm Fly |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.267
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.259
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
20 |
0.258
|
|
|
|
gland morphogenesis
|
GO:0022612 |
12 |
0.254
|
Mouse |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.252
|
Human Mouse Rat Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.252
|
Human Mouse Rat Fly |
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.251
|
Human Mouse Rat Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.250
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
35 |
0.250
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.249
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.249
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.247
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.245
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.244
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.244
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.240
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.240
|
Human Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.239
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.238
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.237
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.233
|
Zebrafish Mouse Fly |
|
|
cranial suture morphogenesis
|
GO:0060363 |
4 |
0.231
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.225
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.225
|
Human Zebrafish Mouse Rat Worm |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.223
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.221
|
Human Fly |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.217
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.215
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.212
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
16 |
0.212
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.212
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.209
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.208
|
Mouse |
|
|
reproductive process
|
GO:0022414 |
372 |
0.206
|
Worm Fly |
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.206
|
Zebrafish Mouse Rat Worm Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.206
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.205
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.203
|
|
|
|
head development
|
GO:0060322 |
247 |
0.203
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.202
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.200
|
|
|
|
digestive tract development
|
GO:0048565 |
39 |
0.200
|
Zebrafish Mouse Rat Worm Fly |
|
|
vasculature development
|
GO:0001944 |
70 |
0.200
|
Mouse |
|
|
metal ion transport
|
GO:0030001 |
289 |
0.199
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.198
|
Human Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.198
|
|
|
|
mesoderm development
|
GO:0007498 |
2 |
0.197
|
Mouse Rat Fly |
|
|
catabolic process
|
GO:0009056 |
351 |
0.195
|
Worm |
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.192
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.190
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.189
|
Human Fly |
|
|
mapk cascade
|
GO:0000165 |
140 |
0.185
|
Human Mouse Rat Fly |
|
|
response to nutrient
|
GO:0007584 |
248 |
0.184
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.184
|
Human Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.183
|
Mouse |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.179
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
71 |
0.178
|
Worm Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.176
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.176
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.175
|
Mouse |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.174
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.171
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.171
|
Rat |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.171
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.171
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.170
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.170
|
Human Fly |
|
|
fatty acid transmembrane transport
|
GO:1902001 |
3 |
0.170
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.169
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.169
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.169
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.169
|
Zebrafish |
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.168
|
Worm Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.165
|
|
|
|
cell cell junction organization
|
GO:0045216 |
20 |
0.165
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.165
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.165
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
17 |
0.163
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.160
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.157
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.157
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.156
|
Human Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.156
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.152
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.152
|
|
|
|
cell junction organization
|
GO:0034330 |
21 |
0.150
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.150
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.150
|
Worm Fly |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.149
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.149
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.149
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.147
|
Human Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.146
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.145
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.145
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
28 |
0.145
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.144
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.142
|
Mouse |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.142
|
Mouse |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.141
|
Zebrafish Mouse Rat Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.141
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.139
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.139
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.138
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.136
|
Human Zebrafish Mouse Rat Worm |
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.136
|
Worm Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.135
|
Fly |
|
|
regulation of jnk cascade
|
GO:0046328 |
19 |
0.135
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.135
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
7 |
0.135
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.135
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.132
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
7 |
0.132
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.131
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.131
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.131
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.130
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.130
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.130
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.129
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.129
|
Human Fly |
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
4 |
0.129
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.128
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.127
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.127
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.127
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.127
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.126
|
Human Fly |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.126
|
Human Mouse Rat Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.126
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.125
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.125
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.124
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.123
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.123
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.123
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.122
|
Worm Fly |
|
|
intracellular transport
|
GO:0046907 |
185 |
0.122
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.122
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.121
|
Human Zebrafish Mouse Rat Worm |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.121
|
Fly |
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.120
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.120
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.119
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.118
|
Human Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.118
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.118
|
|
|
|
tube morphogenesis
|
GO:0035239 |
23 |
0.117
|
Zebrafish Mouse Rat Worm Fly |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.116
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.115
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.110
|
Mouse Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.109
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.108
|
Zebrafish |
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.108
|
Worm |
|
|
response to growth factor
|
GO:0070848 |
189 |
0.107
|
Human Zebrafish Mouse Rat Worm |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.107
|
Human Fly |
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.107
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.107
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.106
|
Human Fly |
|
|
single organism behavior
|
GO:0044708 |
130 |
0.103
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
21 |
0.101
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.101
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.100
|
Worm Fly |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
4 |
0.100
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.100
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
30 |
0.100
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.100
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
8 |
0.098
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.098
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.098
|
|
|
|
limb morphogenesis
|
GO:0035108 |
4 |
0.098
|
Mouse |
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.098
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.098
|
Worm |
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.096
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
1 |
0.096
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.095
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.095
|
|
|
|
bone mineralization
|
GO:0030282 |
11 |
0.095
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.093
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.093
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.092
|
|
|
|
gastrulation
|
GO:0007369 |
2 |
0.092
|
Zebrafish Mouse Rat Fly |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.092
|
Fly |
|
|
lipid transport
|
GO:0006869 |
61 |
0.091
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.090
|
Human Fly |
|
|
digestive system development
|
GO:0055123 |
41 |
0.089
|
Zebrafish Mouse Rat Worm Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.089
|
Worm Fly |
|
|
negative regulation of growth
|
GO:0045926 |
37 |
0.089
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.088
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.088
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.088
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
17 |
0.088
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.088
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.087
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.087
|
Zebrafish Mouse Fly |
|
|
tissue regeneration
|
GO:0042246 |
36 |
0.086
|
Zebrafish |
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.085
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.085
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.084
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.084
|
Human Mouse Rat Fly |
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.083
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.083
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.083
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.082
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.082
|
Human Mouse Rat Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
5 |
0.081
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.081
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.079
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.079
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.079
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.078
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
22 |
0.078
|
Zebrafish Mouse Rat Fly |
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.078
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.078
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.078
|
|
|
|
protein catabolic process
|
GO:0030163 |
30 |
0.078
|
Worm |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
20 |
0.078
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.077
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.077
|
Mouse |
|
|
response to ketone
|
GO:1901654 |
182 |
0.076
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.076
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.076
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.076
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
19 |
0.076
|
|
|
|
lipid localization
|
GO:0010876 |
62 |
0.075
|
|
|
|
response to amino acid
|
GO:0043200 |
75 |
0.075
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
32 |
0.074
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.074
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.074
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.073
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.073
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.073
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.073
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.072
|
Fly |
|
|
response to hexose
|
GO:0009746 |
144 |
0.072
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.072
|
Human Mouse Rat Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.071
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.071
|
|
|
|
jnk cascade
|
GO:0007254 |
28 |
0.071
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
24 |
0.071
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.070
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.070
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
41 |
0.070
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
19 |
0.070
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.070
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.070
|
|
|
|
axon choice point recognition
|
GO:0016198 |
2 |
0.070
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.069
|
Mouse |
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.069
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.069
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.069
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
4 |
0.069
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
22 |
0.069
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.068
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.068
|
Rat Worm Fly |
|
|
myelination
|
GO:0042552 |
39 |
0.068
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
4 |
0.068
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.068
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.067
|
Zebrafish Mouse Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.067
|
|
|
|
protein maturation
|
GO:0051604 |
68 |
0.067
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.067
|
|
|
|
activation of protein kinase b activity
|
GO:0032148 |
3 |
0.066
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.066
|
Human |
|
|
neurological system process
|
GO:0050877 |
219 |
0.066
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.066
|
Worm Fly |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.066
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
23 |
0.065
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.065
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.065
|
Human Fly |
|
|
regulation of plasma membrane long chain fatty acid transport
|
GO:0010746 |
2 |
0.065
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.064
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.063
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.063
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.063
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.063
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.063
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.062
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.062
|
Worm Fly |
|
|
salivary gland development
|
GO:0007431 |
3 |
0.062
|
Mouse |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
14 |
0.062
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.061
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.061
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
2 |
0.061
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.061
|
Worm |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
30 |
0.061
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
15 |
0.060
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
14 |
0.060
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.060
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.060
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.060
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.060
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.060
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.060
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.059
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.059
|
Worm Fly |
|
|
neuron projection development
|
GO:0031175 |
273 |
0.058
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.058
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.058
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.058
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.058
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.058
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.057
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
4 |
0.057
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.057
|
Mouse Fly |
|
|
cytokine production
|
GO:0001816 |
61 |
0.057
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.056
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.056
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.056
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.056
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
53 |
0.056
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.056
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.056
|
Fly |
|
|
action potential
|
GO:0001508 |
54 |
0.055
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
130 |
0.055
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.055
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
2 |
0.055
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.055
|
Worm |
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.055
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.055
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.055
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.055
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.054
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
4 |
0.054
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.054
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.054
|
Fly |
|
|
positive regulation of bone mineralization
|
GO:0030501 |
4 |
0.054
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.054
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
2 |
0.054
|
|
|
|
aging
|
GO:0007568 |
241 |
0.054
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.053
|
Mouse |
|
|
muscle structure development
|
GO:0061061 |
87 |
0.053
|
Mouse Worm Fly |
|
|
learning or memory
|
GO:0007611 |
90 |
0.053
|
|
|
|
atp metabolic process
|
GO:0046034 |
72 |
0.053
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.053
|
|
|
|
vasculogenesis
|
GO:0001570 |
3 |
0.053
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.053
|
|
|
|
protein import
|
GO:0017038 |
37 |
0.052
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.052
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.052
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.052
|
|
|
|
positive regulation of odontogenesis of dentin containing tooth
|
GO:0042488 |
1 |
0.052
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.051
|
|
|
|
axon ensheathment
|
GO:0008366 |
40 |
0.051
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.051
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.050
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.050
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.050
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
2 |
0.050
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.049
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.049
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.049
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.048
|
Rat Worm Fly |
|
|
response to insulin
|
GO:0032868 |
133 |
0.048
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
118 |
0.048
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
33 |
0.048
|
|
|
|
gliogenesis
|
GO:0042063 |
93 |
0.048
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.048
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.047
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.047
|
Worm Fly |
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.047
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.047
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.047
|
|
|
|
growth
|
GO:0040007 |
165 |
0.047
|
Zebrafish Mouse Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.047
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.047
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.046
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.046
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
20 |
0.046
|
Zebrafish Mouse Fly |
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.046
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
4 |
0.046
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.045
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.045
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.045
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.045
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.045
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
75 |
0.045
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.045
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.045
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.045
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.045
|
Mouse |
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.045
|
Rat |
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.044
|
Worm Fly |
|
|
response to estradiol
|
GO:0032355 |
164 |
0.044
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.044
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.044
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
22 |
0.044
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.044
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.044
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
4 |
0.043
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.042
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.042
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
2 |
0.042
|
|
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.042
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.042
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
4 |
0.042
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.041
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
46 |
0.041
|
Human Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.041
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
59 |
0.041
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
59 |
0.041
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.041
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
16 |
0.041
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.041
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
36 |
0.041
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.041
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.041
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
1 |
0.041
|
Zebrafish Mouse Rat Fly |
|
|
reproductive system development
|
GO:0061458 |
128 |
0.041
|
Worm Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.040
|
|
|
|
protein import into nucleus
|
GO:0006606 |
35 |
0.040
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
16 |
0.040
|
Rat |