|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.974
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.973
|
Rat Fly |
|
|
cell projection organization
|
GO:0030030 |
302 |
0.968
|
Zebrafish Mouse Rat Fly |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.919
|
Mouse Rat Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.918
|
Zebrafish Mouse Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.914
|
Mouse Fly |
|
|
neuron development
|
GO:0048666 |
286 |
0.908
|
Mouse Rat Fly |
|
|
locomotion
|
GO:0040011 |
237 |
0.886
|
Rat Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.856
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.847
|
Mouse Rat Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.841
|
Mouse Fly |
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.832
|
Human Mouse Rat Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.822
|
Mouse Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.817
|
Zebrafish Mouse Fly |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.812
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.788
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.773
|
Zebrafish Mouse Rat |
|
|
cell migration
|
GO:0016477 |
197 |
0.762
|
Rat Fly |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.760
|
Rat Fly |
|
|
chemotaxis
|
GO:0006935 |
66 |
0.756
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.755
|
Mouse Rat |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.739
|
Human Mouse Rat Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
16 |
0.734
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.717
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.714
|
Rat Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.714
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.709
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.709
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.700
|
Mouse Rat |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.694
|
Mouse Rat |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.688
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.684
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.678
|
Human Mouse Rat Fly |
|
|
head development
|
GO:0060322 |
247 |
0.669
|
Zebrafish Mouse Rat |
|
|
response to estradiol
|
GO:0032355 |
164 |
0.663
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.656
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.624
|
Rat Fly |
|
|
dendrite morphogenesis
|
GO:0048813 |
43 |
0.620
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.617
|
Human Mouse Rat Fly |
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.616
|
Mouse Rat |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.615
|
Mouse Rat |
|
|
response to wounding
|
GO:0009611 |
254 |
0.613
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.612
|
Rat |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.610
|
Fly |
|
|
response to other organism
|
GO:0051707 |
220 |
0.604
|
Fly |
|
|
developmental growth
|
GO:0048589 |
100 |
0.602
|
Mouse Fly |
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.601
|
Mouse Rat |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.600
|
Rat Fly |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.596
|
Human Mouse Rat Fly |
|
|
central nervous system development
|
GO:0007417 |
311 |
0.593
|
Zebrafish Mouse Rat Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.591
|
Rat Fly |
|
|
central nervous system neuron development
|
GO:0021954 |
5 |
0.588
|
Mouse Rat |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.576
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.574
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.573
|
Mouse Rat |
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.571
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.567
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.563
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.561
|
Human |
|
|
mesoderm development
|
GO:0007498 |
2 |
0.557
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.555
|
Human Mouse Rat Fly |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.549
|
Human Mouse Rat Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.545
|
Rat Fly |
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.539
|
Mouse Rat |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.535
|
Mouse Rat Fly |
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.525
|
Mouse Rat |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.524
|
Rat |
|
|
regeneration
|
GO:0031099 |
163 |
0.521
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.519
|
Mouse Rat |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.517
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.513
|
Mouse |
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.513
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.501
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.494
|
Mouse Rat |
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.494
|
Rat |
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.490
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.482
|
Rat |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.480
|
Human Mouse Rat Fly |
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.478
|
Rat Fly |
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.478
|
Mouse Rat |
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.477
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.471
|
Mouse Rat Fly |
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.466
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.466
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.465
|
Mouse Rat |
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.460
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.454
|
Human Mouse Rat Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.447
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.438
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.437
|
Mouse Rat |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.437
|
Mouse Rat Fly |
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.433
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.428
|
Rat Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.427
|
Mouse |
|
|
apoptotic process
|
GO:0006915 |
381 |
0.421
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.412
|
Mouse Rat |
|
|
dendrite development
|
GO:0016358 |
72 |
0.410
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.403
|
Mouse |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.401
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.401
|
Rat |
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.384
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.379
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.378
|
Mouse Fly |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.377
|
Mouse Rat |
|
|
negative regulation of muscle cell apoptotic process
|
GO:0010656 |
21 |
0.371
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
4 |
0.365
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.364
|
Rat |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.363
|
Human Mouse Rat Fly |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.363
|
Mouse Rat |
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.356
|
Human Mouse Fly |
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.356
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.354
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.351
|
Rat Fly |
|
|
cell chemotaxis
|
GO:0060326 |
31 |
0.347
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.345
|
Mouse Fly |
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.343
|
Zebrafish Fly |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.343
|
Zebrafish Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.342
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.340
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.340
|
Human Mouse Rat Fly |
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.334
|
Human Mouse Rat Fly |
|
|
axonogenesis
|
GO:0007409 |
71 |
0.331
|
Mouse Fly |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
23 |
0.331
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.329
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.328
|
Fly |
|
|
organ regeneration
|
GO:0031100 |
101 |
0.316
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.311
|
Human Mouse Rat Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.311
|
Fly |
|
|
cerebral cortex tangential migration
|
GO:0021800 |
1 |
0.309
|
Rat |
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.307
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.302
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.302
|
Mouse |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.301
|
Fly |
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.299
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.297
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.290
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
110 |
0.287
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.287
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.286
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.284
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.283
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.283
|
Fly |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.281
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.280
|
Human Mouse Rat Fly |
|
|
telencephalon development
|
GO:0021537 |
62 |
0.278
|
Rat |
|
|
tissue regeneration
|
GO:0042246 |
36 |
0.275
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.274
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.271
|
Fly |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.267
|
Rat |
|
|
kidney development
|
GO:0001822 |
67 |
0.263
|
Mouse |
|
|
reproductive process
|
GO:0022414 |
372 |
0.261
|
Mouse Fly |
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.258
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.255
|
Human Mouse Rat Fly |
|
|
urogenital system development
|
GO:0001655 |
78 |
0.253
|
Mouse Fly |
|
|
blood vessel development
|
GO:0001568 |
69 |
0.252
|
Mouse |
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.251
|
|
|
|
gliogenesis
|
GO:0042063 |
93 |
0.247
|
Fly |
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.246
|
Zebrafish Mouse Fly |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.246
|
Rat |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.246
|
Mouse |
|
|
reproduction
|
GO:0000003 |
245 |
0.242
|
Fly |
|
|
neural crest cell migration
|
GO:0001755 |
1 |
0.240
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.239
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.239
|
Zebrafish Mouse Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
4 |
0.238
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.236
|
Mouse Rat |
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.236
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.235
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.235
|
Mouse |
|
|
eye morphogenesis
|
GO:0048592 |
4 |
0.234
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
22 |
0.234
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.232
|
Mouse Rat |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.228
|
Mouse Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.227
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.227
|
|
|
|
liver development
|
GO:0001889 |
90 |
0.225
|
Zebrafish |
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.225
|
Human Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.223
|
Mouse Rat |
|
|
anion transport
|
GO:0006820 |
178 |
0.222
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.220
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.219
|
Fly |
|
|
neuron projection guidance
|
GO:0097485 |
24 |
0.219
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.218
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.218
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.216
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.215
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.214
|
Rat Fly |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
14 |
0.211
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.211
|
Human Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.207
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.203
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.203
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
51 |
0.202
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.201
|
Human Mouse Rat Fly |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.201
|
Mouse Rat |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
17 |
0.200
|
Mouse Rat |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
14 |
0.200
|
Rat |
|
|
regulation of transforming growth factor beta3 production
|
GO:0032910 |
2 |
0.200
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
62 |
0.198
|
Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.197
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.195
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.195
|
Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.191
|
Mouse Rat |
|
|
inflammatory response
|
GO:0006954 |
150 |
0.190
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.190
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.189
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.189
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.187
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.183
|
Mouse Rat |
|
|
kidney epithelium development
|
GO:0072073 |
19 |
0.182
|
Mouse |
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.182
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.182
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.181
|
Fly |
|
|
neural crest cell development
|
GO:0014032 |
2 |
0.180
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
14 |
0.180
|
Mouse Fly |
|
|
axon development
|
GO:0061564 |
96 |
0.180
|
Mouse Fly |
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
2 |
0.179
|
|
|
|
glomerulus morphogenesis
|
GO:0072102 |
1 |
0.178
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.177
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.175
|
Mouse Fly |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.175
|
Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
1 |
0.175
|
Mouse |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
1 |
0.175
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
20 |
0.174
|
Mouse Fly |
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.171
|
Human |
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.166
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.163
|
Fly |
|
|
aging
|
GO:0007568 |
241 |
0.163
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.163
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.161
|
Fly |
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
1 |
0.160
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.160
|
Rat Fly |
|
|
immune system process
|
GO:0002376 |
204 |
0.159
|
Mouse Fly |
|
|
response to growth factor
|
GO:0070848 |
189 |
0.159
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.158
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.157
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
42 |
0.157
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.157
|
|
|
|
axon guidance
|
GO:0007411 |
24 |
0.156
|
|
|
|
forebrain neuron development
|
GO:0021884 |
3 |
0.156
|
Mouse Rat |
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.156
|
Fly |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.154
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.154
|
Fly |
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.153
|
Fly |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.153
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
3 |
0.153
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
33 |
0.153
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.152
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.152
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.151
|
Zebrafish Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.150
|
|
|
|
gastrulation
|
GO:0007369 |
2 |
0.150
|
|
|
|
muscle organ development
|
GO:0007517 |
50 |
0.149
|
Mouse Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
4 |
0.149
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.148
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.148
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.147
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
39 |
0.145
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.145
|
Zebrafish Mouse |
|
|
positive regulation of bone mineralization
|
GO:0030501 |
4 |
0.145
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.145
|
|
|
|
neuron recognition
|
GO:0008038 |
9 |
0.144
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
26 |
0.144
|
Rat |
|
|
limb morphogenesis
|
GO:0035108 |
4 |
0.143
|
Mouse |
|
|
connective tissue development
|
GO:0061448 |
33 |
0.142
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
3 |
0.140
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.139
|
|
|
|
lymphocyte activation
|
GO:0046649 |
43 |
0.139
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.137
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.133
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.131
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
25 |
0.131
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
26 |
0.131
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.131
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.131
|
Mouse Fly |
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.130
|
|
|
|
transforming growth factor beta3 production
|
GO:0032907 |
2 |
0.129
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.128
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.127
|
Human Mouse Rat Fly |
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.125
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.124
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.124
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
49 |
0.123
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.123
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.122
|
Mouse |
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.121
|
Fly |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.120
|
Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
1 |
0.120
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
17 |
0.120
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
29 |
0.120
|
|
|
|
axon extension involved in axon guidance
|
GO:0048846 |
6 |
0.119
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.118
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.118
|
Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.118
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.118
|
Rat |
|
|
response to hexose
|
GO:0009746 |
144 |
0.117
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.117
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.116
|
|
|
|
cell fate determination
|
GO:0001709 |
2 |
0.115
|
Fly |
|
|
cell activation
|
GO:0001775 |
97 |
0.115
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.115
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
46 |
0.114
|
Fly |
|
|
neural crest cell differentiation
|
GO:0014033 |
2 |
0.114
|
|
|
|
response to retinoic acid
|
GO:0032526 |
63 |
0.112
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
72 |
0.112
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.111
|
Mouse |
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.111
|
Mouse |
|
|
regulation of muscle cell apoptotic process
|
GO:0010660 |
26 |
0.111
|
|
|
|
mesoderm formation
|
GO:0001707 |
1 |
0.110
|
|
|
|
salivary gland development
|
GO:0007431 |
3 |
0.110
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
68 |
0.110
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
2 |
0.110
|
Human |
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.110
|
Fly |
|
|
myeloid leukocyte migration
|
GO:0097529 |
20 |
0.110
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.109
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.109
|
Mouse Fly |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.109
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.107
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.107
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.107
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.107
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.106
|
Rat |
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.106
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.106
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.106
|
Mouse |
|
|
positive regulation of muscle organ development
|
GO:0048636 |
13 |
0.105
|
Mouse |
|
|
protein processing
|
GO:0016485 |
68 |
0.104
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.104
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.104
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
72 |
0.103
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.102
|
Fly |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.102
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
72 |
0.102
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.101
|
Mouse |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.101
|
Mouse |
|
|
response to heat
|
GO:0009408 |
60 |
0.100
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.100
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.100
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.099
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.098
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.097
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.097
|
Zebrafish Mouse Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.097
|
|
|
|
skeletal system development
|
GO:0001501 |
41 |
0.096
|
Human Mouse |
|
|
renal system development
|
GO:0072001 |
67 |
0.096
|
Mouse Fly |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.095
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.095
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.095
|
Mouse |
|
|
immune response
|
GO:0006955 |
104 |
0.094
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.093
|
|
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.093
|
Mouse Fly |
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.093
|
Human Fly |
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.093
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.091
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.091
|
Fly |
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.090
|
|
|
|
mesonephros development
|
GO:0001823 |
14 |
0.090
|
Mouse |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.090
|
|
|
|
muscle cell apoptotic process
|
GO:0010657 |
30 |
0.089
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
69 |
0.089
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
8 |
0.089
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.088
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
48 |
0.088
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.087
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.087
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
8 |
0.086
|
Mouse Rat |
|
|
blood circulation
|
GO:0008015 |
183 |
0.085
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
3 |
0.085
|
|
|
|
positive regulation of the force of heart contraction by norepinephrine
|
GO:0003061 |
1 |
0.085
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.085
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.084
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.083
|
|
|
|
glial cell development
|
GO:0021782 |
19 |
0.082
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.082
|
Fly |
|
|
regulation of chemotaxis
|
GO:0050920 |
29 |
0.081
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
10 |
0.080
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
90 |
0.079
|
Zebrafish |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.079
|
Mouse |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
4 |
0.079
|
Mouse Rat |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
33 |
0.079
|
Mouse Fly |
|
|
regulation of defense response
|
GO:0031347 |
68 |
0.078
|
Fly |
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.078
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.078
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
38 |
0.078
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.078
|
Mouse Fly |
|
|
eye development
|
GO:0001654 |
50 |
0.077
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.077
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.077
|
Mouse Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
30 |
0.076
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.076
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
6 |
0.076
|
|
|
|
glomerular epithelial cell differentiation
|
GO:0072311 |
2 |
0.076
|
|
|
|
bone development
|
GO:0060348 |
25 |
0.075
|
Mouse |
|
|
heart development
|
GO:0007507 |
72 |
0.075
|
Zebrafish Mouse Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.075
|
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
10 |
0.074
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.074
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
289 |
0.074
|
|
|
|
embryo development
|
GO:0009790 |
49 |
0.072
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.072
|
Human |
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.071
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.070
|
|
|
|
gamma aminobutyric acid transport
|
GO:0015812 |
8 |
0.070
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.070
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
3 |
0.069
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.069
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
1 |
0.068
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.068
|
|
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.068
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
3 |
0.067
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.067
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
47 |
0.067
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
4 |
0.067
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
10 |
0.067
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.067
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.067
|
Rat |
|
|
lymphocyte proliferation
|
GO:0046651 |
29 |
0.067
|
|
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
9 |
0.066
|
Mouse |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.065
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.065
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.065
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
1 |
0.064
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
12 |
0.063
|
|
|
|
interleukin 1 production
|
GO:0032612 |
11 |
0.063
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.063
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
3 |
0.063
|
|
|
|
odontogenesis
|
GO:0042476 |
32 |
0.063
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.063
|
|
|
|
renin secretion into blood stream
|
GO:0002001 |
1 |
0.062
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.062
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
14 |
0.062
|
|
|
|
lymphoid progenitor cell differentiation
|
GO:0002320 |
2 |
0.062
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.062
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.061
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.060
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.060
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
22 |
0.060
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.060
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
13 |
0.060
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.060
|
|
|
|
camera type eye development
|
GO:0043010 |
48 |
0.059
|
Mouse |
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.059
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.059
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
14 |
0.059
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.058
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
2 |
0.058
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.058
|
|
|
|
gland morphogenesis
|
GO:0022612 |
12 |
0.058
|
Mouse |
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.058
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.057
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.057
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
40 |
0.057
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.057
|
|
|
|
chronic inflammatory response to non antigenic stimulus
|
GO:0002545 |
1 |
0.056
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.056
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.056
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.055
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.055
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.055
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.055
|
Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.054
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
51 |
0.054
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.054
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.054
|
|
|
|
detection of external stimulus
|
GO:0009581 |
13 |
0.054
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
29 |
0.053
|
|
|
|
acetylcholine secretion
|
GO:0061526 |
4 |
0.053
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.053
|
|
|
|
response to histamine
|
GO:0034776 |
3 |
0.053
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.053
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.053
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
25 |
0.052
|
Mouse |
|
|
regulation of skeletal muscle tissue growth
|
GO:0048631 |
3 |
0.052
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.052
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
12 |
0.052
|
Mouse |
|
|
skeletal system morphogenesis
|
GO:0048705 |
12 |
0.052
|
Human Mouse |
|
|
cartilage development
|
GO:0051216 |
22 |
0.051
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
7 |
0.051
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.051
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
1 |
0.051
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
68 |
0.051
|
|
|
|
vasculogenesis
|
GO:0001570 |
3 |
0.051
|
|
|
|
signal transduction involved in regulation of gene expression
|
GO:0023019 |
4 |
0.050
|
|