Rattus norvegicus

0 known processes

Fli1

Friend leukemia virus integration 1

Fli1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell proliferation GO:0008284 249 0.230
regulation of cell proliferation GO:0042127 359 0.215
sensory perception GO:0007600 101 0.187
regulation of multicellular organismal development GO:2000026 376 0.135
regulation of rna metabolic process GO:0051252 391 0.129
homeostatic process GO:0042592 331 0.121
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.118
transcription dna templated GO:0006351 377 0.117
regulation of anatomical structure morphogenesis GO:0022603 141 0.117
cellular response to oxygen containing compound GO:1901701 386 0.110
cellular component assembly GO:0022607 360 0.109
regulation of protein metabolic process GO:0051246 289 0.107
cellular response to external stimulus GO:0071496 118 0.100
positive regulation of gene expression GO:0010628 244 0.098
organic acid metabolic process GO:0006082 292 0.097
rna biosynthetic process GO:0032774 380 0.095
positive regulation of developmental process GO:0051094 283 0.094
circadian rhythm GO:0007623 88 0.090
gland development GO:0048732 155 0.089
positive regulation of cellular biosynthetic process GO:0031328 295 0.087
regulation of response to stress GO:0080134 126 0.084
positive regulation of multicellular organismal process GO:0051240 387 0.084
nitrogen compound transport GO:0071705 229 0.084
cellular response to lipid GO:0071396 201 0.083
regulation of response to external stimulus GO:0032101 106 0.083
carboxylic acid metabolic process GO:0019752 289 0.082
smooth muscle cell proliferation GO:0048659 77 0.082
regulation of programmed cell death GO:0043067 341 0.077
regulation of rna biosynthetic process GO:2001141 381 0.076
transcription from rna polymerase ii promoter GO:0006366 252 0.073
positive regulation of immune system process GO:0002684 90 0.073
cellular response to abiotic stimulus GO:0071214 85 0.072
reproductive process GO:0022414 372 0.071
cellular calcium ion homeostasis GO:0006874 160 0.071
positive regulation of biosynthetic process GO:0009891 319 0.068
positive regulation of phosphate metabolic process GO:0045937 262 0.068
defense response GO:0006952 194 0.067
response to nutrient GO:0007584 248 0.067
single organism reproductive process GO:0044702 297 0.066
response to extracellular stimulus GO:0009991 380 0.066
positive regulation of protein metabolic process GO:0051247 178 0.066
cellular response to peptide GO:1901653 133 0.066
neurological system process GO:0050877 219 0.066
macromolecular complex assembly GO:0065003 273 0.066
tissue development GO:0009888 252 0.065
response to nutrient levels GO:0031667 370 0.065
cellular chemical homeostasis GO:0055082 247 0.064
response to peptide GO:1901652 292 0.064
inflammatory response GO:0006954 150 0.064
regulation of apoptotic process GO:0042981 335 0.063
response to biotic stimulus GO:0009607 226 0.063
positive regulation of transcription dna templated GO:0045893 197 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
programmed cell death GO:0012501 392 0.061
rna metabolic process GO:0016070 406 0.060
fatty acid metabolic process GO:0006631 99 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
response to oxygen levels GO:0070482 265 0.055
positive regulation of programmed cell death GO:0043068 157 0.055
regulation of transcription dna templated GO:0006355 374 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.054
apoptotic process GO:0006915 381 0.054
regulation of molecular function GO:0065009 398 0.053
muscle cell proliferation GO:0033002 84 0.052
response to external biotic stimulus GO:0043207 221 0.052
positive regulation of cell death GO:0010942 184 0.052
oxoacid metabolic process GO:0043436 290 0.051
response to inorganic substance GO:0010035 377 0.048
neuron differentiation GO:0030182 368 0.048
cellular homeostasis GO:0019725 252 0.048
regulation of phagocytosis engulfment GO:0060099 4 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.048
oxidation reduction process GO:0055114 304 0.047
single organism behavior GO:0044708 130 0.046
immune system process GO:0002376 204 0.045
response to decreased oxygen levels GO:0036293 237 0.045
multi organism reproductive process GO:0044703 262 0.044
regulation of cell differentiation GO:0045595 320 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
positive regulation of apoptotic process GO:0043065 154 0.044
single organism catabolic process GO:0044712 283 0.044
single organism biosynthetic process GO:0044711 342 0.044
monocarboxylic acid metabolic process GO:0032787 152 0.044
epithelium development GO:0060429 96 0.044
behavior GO:0007610 205 0.043
lipid metabolic process GO:0006629 283 0.043
positive regulation of cell differentiation GO:0045597 217 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.042
positive regulation of signaling GO:0023056 270 0.042
reproduction GO:0000003 245 0.042
regulation of cell development GO:0060284 263 0.042
organic hydroxy compound metabolic process GO:1901615 115 0.042
response to oxidative stress GO:0006979 186 0.042
negative regulation of metabolic process GO:0009892 331 0.041
divalent inorganic cation homeostasis GO:0072507 165 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
response to acid chemical GO:0001101 222 0.040
positive regulation of cell development GO:0010720 176 0.039
anatomical structure morphogenesis GO:0009653 298 0.039
chemical homeostasis GO:0048878 292 0.038
circulatory system process GO:0003013 183 0.038
nucleic acid templated transcription GO:0097659 379 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
response to peptide hormone GO:0043434 278 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
protein phosphorylation GO:0006468 345 0.036
cation transport GO:0006812 382 0.035
cellular metal ion homeostasis GO:0006875 172 0.035
regulation of smooth muscle cell proliferation GO:0048660 75 0.035
regulation of catalytic activity GO:0050790 304 0.034
immune response GO:0006955 104 0.034
cation homeostasis GO:0055080 195 0.034
acute inflammatory response GO:0002526 58 0.034
organophosphate biosynthetic process GO:0090407 143 0.034
negative regulation of cell proliferation GO:0008285 119 0.034
cellular cation homeostasis GO:0030003 180 0.033
regulation of body fluid levels GO:0050878 90 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
cell morphogenesis GO:0000902 142 0.032
cellular amine metabolic process GO:0044106 38 0.032
cellular response to organic cyclic compound GO:0071407 202 0.031
response to mechanical stimulus GO:0009612 134 0.031
response to hypoxia GO:0001666 231 0.031
blood circulation GO:0008015 183 0.031
cellular response to mechanical stimulus GO:0071260 48 0.031
response to carbohydrate GO:0009743 183 0.031
lymphocyte activation GO:0046649 43 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
ion homeostasis GO:0050801 212 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
positive regulation of cell communication GO:0010647 271 0.030
catabolic process GO:0009056 351 0.030
calcium ion homeostasis GO:0055074 162 0.029
amine metabolic process GO:0009308 38 0.029
metal ion transport GO:0030001 289 0.029
cellular response to molecule of bacterial origin GO:0071219 56 0.029
protein complex subunit organization GO:0071822 302 0.029
multicellular organismal reproductive process GO:0048609 233 0.028
regulation of protein modification process GO:0031399 194 0.028
regulation of leukocyte activation GO:0002694 45 0.028
positive regulation of transport GO:0051050 245 0.027
ion transmembrane transport GO:0034220 365 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
metal ion homeostasis GO:0055065 186 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
intracellular signal transduction GO:0035556 314 0.027
regulation of hormone levels GO:0010817 187 0.027
reactive oxygen species metabolic process GO:0072593 37 0.026
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.026
negative regulation of apoptotic process GO:0043066 181 0.026
positive regulation of cytoplasmic transport GO:1903651 32 0.026
multicellular organism reproduction GO:0032504 233 0.026
neuron apoptotic process GO:0051402 88 0.026
regulation of neuron death GO:1901214 115 0.026
cardiovascular system development GO:0072358 134 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
positive regulation of phagocytosis engulfment GO:0060100 4 0.025
response to estradiol GO:0032355 164 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
response to other organism GO:0051707 220 0.025
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
cell type specific apoptotic process GO:0097285 134 0.025
regulation of immune system process GO:0002682 123 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
regulation of response to wounding GO:1903034 69 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
proteolysis GO:0006508 175 0.024
multi multicellular organism process GO:0044706 138 0.024
regulation of nervous system development GO:0051960 264 0.024
cellular response to stress GO:0033554 269 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
response to growth factor GO:0070848 189 0.023
protein complex biogenesis GO:0070271 263 0.023
regulation of neurogenesis GO:0050767 247 0.023
heart contraction GO:0060047 57 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
regulation of neuron apoptotic process GO:0043523 83 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
circulatory system development GO:0072359 134 0.022
small molecule biosynthetic process GO:0044283 124 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
ras protein signal transduction GO:0007265 29 0.022
growth GO:0040007 165 0.022
regulation of blood vessel size GO:0050880 89 0.022
cellular catabolic process GO:0044248 295 0.022
response to lipopolysaccharide GO:0032496 191 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
protein oligomerization GO:0051259 191 0.022
regulation of cellular localization GO:0060341 263 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
positive regulation of protein modification process GO:0031401 142 0.021
cell growth GO:0016049 104 0.021
t cell activation GO:0042110 29 0.021
regulation of system process GO:0044057 208 0.021
aging GO:0007568 241 0.021
regulation of anatomical structure size GO:0090066 135 0.021
cellular component biogenesis GO:0044085 368 0.021
neuron death GO:0070997 127 0.021
organophosphate metabolic process GO:0019637 370 0.021
cellular lipid metabolic process GO:0044255 208 0.021
positive regulation of molecular function GO:0044093 230 0.021
nucleoside metabolic process GO:0009116 179 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
regulation of intracellular transport GO:0032386 65 0.020
regulation of necroptotic process GO:0060544 2 0.020
regulation of inflammatory response GO:0050727 48 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
response to cytokine GO:0034097 215 0.020
cellular ion homeostasis GO:0006873 184 0.020
divalent inorganic cation transport GO:0072511 134 0.020
negative regulation of gene expression GO:0010629 199 0.019
response to vitamin GO:0033273 131 0.019
protein homooligomerization GO:0051260 91 0.019
calcium ion transport GO:0006816 131 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
regulation of hydrolase activity GO:0051336 143 0.019
positive regulation of signal transduction GO:0009967 175 0.019
icosanoid metabolic process GO:0006690 38 0.019
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 3 0.019
carbohydrate biosynthetic process GO:0016051 42 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
regulation of reactive oxygen species metabolic process GO:2000377 26 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
positive regulation of homeostatic process GO:0032846 49 0.019
organic substance catabolic process GO:1901575 316 0.019
positive regulation of hormone secretion GO:0046887 65 0.018
cellular response to oxidative stress GO:0034599 76 0.018
protein complex assembly GO:0006461 263 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
positive regulation of nervous system development GO:0051962 178 0.018
response to organophosphorus GO:0046683 102 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
vascular process in circulatory system GO:0003018 96 0.018
organelle organization GO:0006996 266 0.018
cellular component morphogenesis GO:0032989 155 0.018
response to wounding GO:0009611 254 0.018
sexual reproduction GO:0019953 148 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cell cycle process GO:0022402 57 0.018
peptidyl amino acid modification GO:0018193 126 0.018
anion transport GO:0006820 178 0.017
alcohol metabolic process GO:0006066 77 0.017
localization of cell GO:0051674 202 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.017
rhythmic process GO:0048511 156 0.017
regeneration GO:0031099 163 0.017
tube development GO:0035295 89 0.017
positive regulation of ion transport GO:0043270 94 0.017
positive regulation of response to external stimulus GO:0032103 51 0.017
regulation of neurological system process GO:0031644 43 0.017
cell motility GO:0048870 202 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
central nervous system development GO:0007417 311 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
eye morphogenesis GO:0048592 4 0.016
hormone transport GO:0009914 121 0.016
lipid biosynthetic process GO:0008610 128 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of cellular component organization GO:0051128 368 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
jak stat cascade GO:0007259 26 0.016
regulation of locomotion GO:0040012 148 0.016
response to activity GO:0014823 73 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
carboxylic acid transport GO:0046942 115 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.016
neuron development GO:0048666 286 0.016
regulation of signal transduction GO:0009966 318 0.016
response to hexose GO:0009746 144 0.016
choline transport GO:0015871 4 0.015
cellular ketone metabolic process GO:0042180 51 0.015
cell migration GO:0016477 197 0.015
regulation of cell motility GO:2000145 131 0.015
response to toxic substance GO:0009636 133 0.015
renal system development GO:0072001 67 0.015
protein heterooligomerization GO:0051291 89 0.015
cellular response to acid chemical GO:0071229 75 0.015
regulation of homeostatic process GO:0032844 101 0.015
liver development GO:0001889 90 0.015
blood vessel development GO:0001568 69 0.015
carbohydrate metabolic process GO:0005975 130 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
developmental process involved in reproduction GO:0003006 159 0.015
response to estrogen GO:0043627 232 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
response to corticosteroid GO:0031960 235 0.014
transmembrane transport GO:0055085 412 0.014
sequestering of calcium ion GO:0051208 8 0.014
cell activation GO:0001775 97 0.014
learning or memory GO:0007611 90 0.014
cellular response to lipopolysaccharide GO:0071222 55 0.014
cellular component movement GO:0006928 248 0.014
sensory perception of pain GO:0019233 73 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of cell migration GO:0030335 96 0.014
response to glucocorticoid GO:0051384 223 0.014
regulation of endocytosis GO:0030100 42 0.014
erk1 and erk2 cascade GO:0070371 48 0.013
response to ketone GO:1901654 182 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of cellular component movement GO:0051270 150 0.013
response to metal ion GO:0010038 253 0.013
lipid storage GO:0019915 1 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of signal transduction GO:0009968 83 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of cell motility GO:2000147 97 0.013
anion transmembrane transport GO:0098656 77 0.013
positive regulation of peptide secretion GO:0002793 52 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.013
sequestering of metal ion GO:0051238 9 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
neuron projection development GO:0031175 273 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of dna metabolic process GO:0051052 60 0.013
divalent metal ion transport GO:0070838 132 0.013
necroptotic process GO:0070266 2 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
head development GO:0060322 247 0.012
maintenance of location GO:0051235 17 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
kidney development GO:0001822 67 0.012
epithelial cell differentiation GO:0030855 71 0.012
purine containing compound metabolic process GO:0072521 253 0.012
glucose homeostasis GO:0042593 75 0.012
regulation of blood pressure GO:0008217 83 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of defense response GO:0031347 68 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
cellular response to drug GO:0035690 30 0.012
response to hyperoxia GO:0055093 45 0.012
purine nucleotide metabolic process GO:0006163 229 0.011
amide transport GO:0042886 105 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
response to ethanol GO:0045471 162 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
organ morphogenesis GO:0009887 75 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
respiratory gaseous exchange GO:0007585 4 0.011
developmental growth involved in morphogenesis GO:0060560 33 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of locomotion GO:0040017 102 0.011
response to hydrogen peroxide GO:0042542 89 0.011
regulation of calcium ion transport GO:0051924 77 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
sensory perception of bitter taste GO:0050913 4 0.011
response to osmotic stress GO:0006970 42 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
response to alkaloid GO:0043279 132 0.011
bmp signaling pathway GO:0030509 4 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
heterocycle catabolic process GO:0046700 167 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of phosphorylation GO:0042325 248 0.011
reproductive system development GO:0061458 128 0.011
axis specification GO:0009798 4 0.011
organic acid transport GO:0015849 116 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
response to reactive oxygen species GO:0000302 120 0.011
hepaticobiliary system development GO:0061008 90 0.011
activation of protein kinase activity GO:0032147 47 0.011
rho protein signal transduction GO:0007266 11 0.011
response to bacterium GO:0009617 200 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
negative regulation of humoral immune response GO:0002921 4 0.011
blood vessel morphogenesis GO:0048514 58 0.011
vasodilation GO:0042311 44 0.011
leukocyte differentiation GO:0002521 30 0.011
neuromuscular process GO:0050905 2 0.011
regulation of tube size GO:0035150 89 0.011
actin filament based process GO:0030029 86 0.010
endocytosis GO:0006897 84 0.010
response to radiation GO:0009314 137 0.010
muscle structure development GO:0061061 87 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
multicellular organism growth GO:0035264 1 0.010
negative regulation of neuron death GO:1901215 69 0.010
regulation of transcription regulatory region dna binding GO:2000677 4 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
positive regulation of cellular component movement GO:0051272 102 0.010

Fli1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.056
gastrointestinal system cancer DOID:3119 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016