Rattus norvegicus

140 known processes

Flt1

FMS-related tyrosine kinase 1

(Aliases: VEGFR-1)

Flt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 202 0.929
cellular response to endogenous stimulus GO:0071495 377 0.924
Rat Fly
locomotion GO:0040011 237 0.860
localization of cell GO:0051674 202 0.837
regulation of cellular component movement GO:0051270 150 0.820
cellular component movement GO:0006928 248 0.796
response to reactive oxygen species GO:0000302 120 0.770
Rat
regulation of cell proliferation GO:0042127 359 0.769
chemical homeostasis GO:0048878 292 0.714
cell migration GO:0016477 197 0.679
cellular response to oxygen containing compound GO:1901701 386 0.655
Fly
response to hydrogen peroxide GO:0042542 89 0.640
Rat
response to inorganic substance GO:0010035 377 0.627
Rat
muscle cell proliferation GO:0033002 84 0.614
positive regulation of phosphate metabolic process GO:0045937 262 0.602
blood circulation GO:0008015 183 0.594
Zebrafish
cellular response to peptide GO:1901653 133 0.577
Fly
regulation of locomotion GO:0040012 148 0.565
regulation of programmed cell death GO:0043067 341 0.558
Rat Fly
single organism behavior GO:0044708 130 0.555
cellular component assembly GO:0022607 360 0.551
Fly
cellular response to nitrogen compound GO:1901699 210 0.545
Fly
response to oxidative stress GO:0006979 186 0.541
Rat
tissue development GO:0009888 252 0.531
Mouse Rat Fly
carboxylic acid metabolic process GO:0019752 289 0.525
enzyme linked receptor protein signaling pathway GO:0007167 116 0.519
response to estradiol GO:0032355 164 0.511
Rat
cellular response to organic cyclic compound GO:0071407 202 0.509
Rat
leukocyte activation GO:0045321 76 0.502
Rat
homeostatic process GO:0042592 331 0.485
Rat Fly
cellular response to lipid GO:0071396 201 0.483
Rat
regulation of signal transduction GO:0009966 318 0.463
regulation of smooth muscle cell proliferation GO:0048660 75 0.452
taxis GO:0042330 67 0.452
Human
cellular component morphogenesis GO:0032989 155 0.432
Fly
intracellular signal transduction GO:0035556 314 0.429
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.426
cellular response to steroid hormone stimulus GO:0071383 93 0.425
Rat
regulation of phosphate metabolic process GO:0019220 349 0.424
angiogenesis GO:0001525 53 0.421
Human Zebrafish Mouse
response to mechanical stimulus GO:0009612 134 0.420
inflammatory response GO:0006954 150 0.412
cellular response to growth factor stimulus GO:0071363 162 0.394
metanephric comma shaped body morphogenesis GO:0072278 2 0.393
Rat
positive regulation of phosphorylation GO:0042327 177 0.391
cellular response to hormone stimulus GO:0032870 247 0.385
Rat Fly
cellular catabolic process GO:0044248 295 0.382
organophosphate metabolic process GO:0019637 370 0.382
Human
regulation of system process GO:0044057 208 0.381
response to estrogen GO:0043627 232 0.381
Rat
regulation of cell migration GO:0030334 128 0.380
regulation of immune system process GO:0002682 123 0.379
Mouse Rat Fly
regulation of rna metabolic process GO:0051252 391 0.376
response to wounding GO:0009611 254 0.374
Rat
organelle organization GO:0006996 266 0.372
Fly
regulation of molecular function GO:0065009 398 0.366
anatomical structure morphogenesis GO:0009653 298 0.363
Human Zebrafish Mouse Rat Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.361
neurological system process GO:0050877 219 0.361
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.353
regulation of ion transport GO:0043269 245 0.344
positive regulation of locomotion GO:0040017 102 0.343
negative regulation of apoptotic process GO:0043066 181 0.342
Rat Fly
response to hypoxia GO:0001666 231 0.342
kidney development GO:0001822 67 0.341
Rat
positive regulation of cell migration GO:0030335 96 0.338
cellular response to organonitrogen compound GO:0071417 197 0.336
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.332
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.324
positive regulation of cell motility GO:2000147 97 0.322
cellular response to peptide hormone stimulus GO:0071375 120 0.321
Fly
regulation of hormone secretion GO:0046883 106 0.321
positive regulation of signaling GO:0023056 270 0.316
cation homeostasis GO:0055080 195 0.311
anatomical structure formation involved in morphogenesis GO:0048646 83 0.311
Human Zebrafish Mouse
regulation of calcium ion transport GO:0051924 77 0.302
organic acid metabolic process GO:0006082 292 0.300
regulation of protein phosphorylation GO:0001932 183 0.297
urogenital system development GO:0001655 78 0.292
Rat Fly
ribonucleotide metabolic process GO:0009259 231 0.286
lymphoid progenitor cell differentiation GO:0002320 2 0.283
Rat
response to oxygen levels GO:0070482 265 0.281
negative regulation of cell death GO:0060548 229 0.281
Rat Fly
smooth muscle cell proliferation GO:0048659 77 0.276
organonitrogen compound biosynthetic process GO:1901566 167 0.274
Rat
positive regulation of apoptotic process GO:0043065 154 0.270
regulation of blood vessel size GO:0050880 89 0.268
immune response GO:0006955 104 0.268
Fly
aging GO:0007568 241 0.267
regulation of cell motility GO:2000145 131 0.264
cell morphogenesis GO:0000902 142 0.260
Fly
signal transduction by phosphorylation GO:0023014 144 0.260
muscle system process GO:0003012 115 0.257
rna metabolic process GO:0016070 406 0.256
positive regulation of catalytic activity GO:0043085 184 0.256
regulation of purine nucleotide metabolic process GO:1900542 115 0.255
vascular process in circulatory system GO:0003018 96 0.253
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.251
g protein coupled receptor signaling pathway GO:0007186 242 0.251
cellular homeostasis GO:0019725 252 0.251
regulation of intracellular signal transduction GO:1902531 218 0.249
positive regulation of signal transduction GO:0009967 175 0.248
single organism catabolic process GO:0044712 283 0.248
response to peptide GO:1901652 292 0.248
Fly
regulation of membrane potential GO:0042391 110 0.246
cellular response to cytokine stimulus GO:0071345 127 0.243
Rat
organic substance catabolic process GO:1901575 316 0.243
response to decreased oxygen levels GO:0036293 237 0.241
response to monosaccharide GO:0034284 159 0.240
positive regulation of phosphorus metabolic process GO:0010562 262 0.240
renal system development GO:0072001 67 0.239
Rat Fly
heart contraction GO:0060047 57 0.238
Zebrafish
reproductive process GO:0022414 372 0.238
Fly
apoptotic process GO:0006915 381 0.237
Rat Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.229
response to purine containing compound GO:0014074 126 0.227
negative regulation of multicellular organismal process GO:0051241 203 0.225
Rat
cardiovascular system development GO:0072358 134 0.224
Human Zebrafish Mouse
single organism reproductive process GO:0044702 297 0.222
Fly
response to glucocorticoid GO:0051384 223 0.222
Rat
negative regulation of programmed cell death GO:0043069 183 0.219
Rat Fly
regulation of anatomical structure morphogenesis GO:0022603 141 0.218
Human Fly
metal ion homeostasis GO:0055065 186 0.216
cellular cation homeostasis GO:0030003 180 0.214
positive regulation of nucleotide metabolic process GO:0045981 91 0.212
positive regulation of cell communication GO:0010647 271 0.212
regulation of apoptotic process GO:0042981 335 0.211
Rat Fly
reproduction GO:0000003 245 0.210
Fly
calcium ion homeostasis GO:0055074 162 0.210
eye development GO:0001654 50 0.210
sensory perception GO:0007600 101 0.209
divalent inorganic cation transport GO:0072511 134 0.209
negative regulation of response to stimulus GO:0048585 155 0.209
regulation of phosphorus metabolic process GO:0051174 349 0.208
purine containing compound metabolic process GO:0072521 253 0.205
positive regulation of cell death GO:0010942 184 0.205
oxoacid metabolic process GO:0043436 290 0.202
response to alkaloid GO:0043279 132 0.201
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.201
regulation of blood circulation GO:1903522 110 0.199
Zebrafish
positive regulation of multicellular organismal process GO:0051240 387 0.197
Human Mouse Rat
epithelial cell differentiation GO:0030855 71 0.194
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.191
regulation of protein metabolic process GO:0051246 289 0.190
regulation of rna biosynthetic process GO:2001141 381 0.186
regulation of mesenchymal cell proliferation GO:0010464 4 0.185
carbohydrate derivative metabolic process GO:1901135 346 0.185
Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.180
Rat
endothelial cell differentiation GO:0045446 9 0.180
immune system process GO:0002376 204 0.179
Human Mouse Rat Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.179
negative regulation of cellular biosynthetic process GO:0031327 161 0.178
regulation of cellular localization GO:0060341 263 0.175
negative regulation of cellular metabolic process GO:0031324 281 0.173
cellular response to abiotic stimulus GO:0071214 85 0.172
growth GO:0040007 165 0.171
Rat
glomerulus morphogenesis GO:0072102 1 0.171
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.170
cell differentiation involved in kidney development GO:0061005 4 0.169
defense response GO:0006952 194 0.167
Fly
response to toxic substance GO:0009636 133 0.164
Rat
regulation of vasculature development GO:1901342 44 0.164
Human
negative regulation of biosynthetic process GO:0009890 168 0.164
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.163
protein phosphorylation GO:0006468 345 0.163
cation transport GO:0006812 382 0.162
response to growth factor GO:0070848 189 0.162
response to camp GO:0051591 91 0.162
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.161
regulation of cellular amine metabolic process GO:0033238 8 0.161
purine ribonucleotide catabolic process GO:0009154 136 0.159
multicellular organismal reproductive process GO:0048609 233 0.159
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.157
cation transmembrane transport GO:0098655 263 0.156
regulation of cellular ketone metabolic process GO:0010565 27 0.156
cell activation GO:0001775 97 0.155
Rat
negative regulation of immune system process GO:0002683 39 0.154
Rat
regulation of leukocyte activation GO:0002694 45 0.154
Rat
catabolic process GO:0009056 351 0.154
regulation of cell growth GO:0001558 85 0.153
Rat
muscle contraction GO:0006936 88 0.152
circulatory system process GO:0003013 183 0.151
Zebrafish
nucleoside triphosphate metabolic process GO:0009141 144 0.151
ion homeostasis GO:0050801 212 0.150
negative regulation of transport GO:0051051 136 0.149
neuron differentiation GO:0030182 368 0.149
protein complex biogenesis GO:0070271 263 0.149
regulation of heart contraction GO:0008016 48 0.149
Zebrafish
cellular response to mechanical stimulus GO:0071260 48 0.148
negative regulation of transcription dna templated GO:0045892 116 0.147
skeletal system development GO:0001501 41 0.144
positive regulation of response to stimulus GO:0048584 285 0.144
cellular response to corticosteroid stimulus GO:0071384 69 0.143
Rat
chemotaxis GO:0006935 66 0.141
Human
neuron apoptotic process GO:0051402 88 0.137
regulation of response to wounding GO:1903034 69 0.137
cellular calcium ion homeostasis GO:0006874 160 0.137
mapk cascade GO:0000165 140 0.134
rna biosynthetic process GO:0032774 380 0.133
regulation of secretion GO:0051046 224 0.131
cytosolic calcium ion homeostasis GO:0051480 140 0.130
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.130
response to carbohydrate GO:0009743 183 0.129
transcription from rna polymerase ii promoter GO:0006366 252 0.128
response to cytokine GO:0034097 215 0.128
Rat
behavior GO:0007610 205 0.127
calcium ion transport GO:0006816 131 0.126
blood vessel development GO:0001568 69 0.126
Human Zebrafish Mouse
cellular response to external stimulus GO:0071496 118 0.124
learning or memory GO:0007611 90 0.123
cell cell signaling GO:0007267 335 0.122
nucleotide metabolic process GO:0009117 279 0.121
single organism intracellular transport GO:1902582 166 0.121
divalent metal ion transport GO:0070838 132 0.121
long term synaptic potentiation GO:0060291 21 0.120
positive regulation of cell development GO:0010720 176 0.119
nucleic acid templated transcription GO:0097659 379 0.118
response to bacterium GO:0009617 200 0.116
cellular metal ion homeostasis GO:0006875 172 0.116
glomerular epithelial cell differentiation GO:0072311 2 0.115
metal ion transport GO:0030001 289 0.115
purine nucleotide metabolic process GO:0006163 229 0.114
programmed cell death GO:0012501 392 0.114
Rat Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.114
macromolecular complex assembly GO:0065003 273 0.113
cellular divalent inorganic cation homeostasis GO:0072503 162 0.112
sexual reproduction GO:0019953 148 0.112
Fly
cellular ketone metabolic process GO:0042180 51 0.111
positive regulation of protein kinase activity GO:0045860 73 0.110
developmental process involved in reproduction GO:0003006 159 0.109
Fly
neuron projection morphogenesis GO:0048812 122 0.108
regulation of metal ion transport GO:0010959 118 0.108
ion transmembrane transport GO:0034220 365 0.108
cell type specific apoptotic process GO:0097285 134 0.107
regulation of transcription dna templated GO:0006355 374 0.107
multicellular organism reproduction GO:0032504 233 0.106
Fly
intracellular receptor signaling pathway GO:0030522 35 0.106
regulation of cell differentiation GO:0045595 320 0.104
Mouse Rat Fly
vasculature development GO:0001944 70 0.104
Human Zebrafish Mouse
protein complex assembly GO:0006461 263 0.104
positive regulation of biosynthetic process GO:0009891 319 0.103
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.103
glycosyl compound metabolic process GO:1901657 182 0.103
regulation of neurogenesis GO:0050767 247 0.102
epithelial cell differentiation involved in kidney development GO:0035850 3 0.102
purine ribonucleotide metabolic process GO:0009150 227 0.102
positive regulation of gtpase activity GO:0043547 47 0.101
protein complex subunit organization GO:0071822 302 0.101
Fly
regulation of hydrolase activity GO:0051336 143 0.101
Human
regulation of homeostatic process GO:0032844 101 0.100
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.099
negative regulation of rna metabolic process GO:0051253 123 0.099
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.099
mitotic spindle organization GO:0007052 2 0.099
Fly
ribose phosphate biosynthetic process GO:0046390 87 0.099
establishment of protein localization GO:0045184 141 0.098
cellular chemical homeostasis GO:0055082 247 0.098
monocarboxylic acid metabolic process GO:0032787 152 0.098
leukocyte homeostasis GO:0001776 7 0.097
Rat
cognition GO:0050890 92 0.097
cell part morphogenesis GO:0032990 123 0.097
positive regulation of nucleic acid templated transcription GO:1903508 197 0.097
cell projection organization GO:0030030 302 0.096
Fly
cell morphogenesis involved in differentiation GO:0000904 119 0.096
lipid metabolic process GO:0006629 283 0.095
Human
response to organophosphorus GO:0046683 102 0.095
sequestering of metal ion GO:0051238 9 0.095
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.095
regulation of cellular component organization GO:0051128 368 0.094
Rat Fly
regulation of phosphorylation GO:0042325 248 0.093
positive regulation of protein modification process GO:0031401 142 0.093
regulation of cell development GO:0060284 263 0.092
bmp signaling pathway GO:0030509 4 0.092
cellular response to camp GO:0071320 26 0.091
nucleoside phosphate metabolic process GO:0006753 283 0.091
positive regulation of neurogenesis GO:0050769 165 0.091
regeneration GO:0031099 163 0.091
Rat
endothelium development GO:0003158 12 0.090
regulation of behavior GO:0050795 61 0.089
amide transport GO:0042886 105 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.089
gliogenesis GO:0042063 93 0.089
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.088
response to tumor necrosis factor GO:0034612 56 0.088
positive regulation of transcription dna templated GO:0045893 197 0.088
secretion by cell GO:0032940 248 0.088
positive regulation of programmed cell death GO:0043068 157 0.087
positive regulation of response to external stimulus GO:0032103 51 0.087
regulation of multicellular organismal development GO:2000026 376 0.087
Human Mouse Rat
potassium ion transport GO:0006813 97 0.086
heart morphogenesis GO:0003007 3 0.085
cyclic nucleotide metabolic process GO:0009187 80 0.085
response to dexamethasone GO:0071548 49 0.084
negative regulation of long term synaptic potentiation GO:1900272 1 0.082
peptidyl amino acid modification GO:0018193 126 0.082
regulation of cellular protein metabolic process GO:0032268 267 0.082
neuron development GO:0048666 286 0.081
transmembrane transport GO:0055085 412 0.081
blood vessel morphogenesis GO:0048514 58 0.081
Human Zebrafish Mouse
protein localization GO:0008104 191 0.081
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.081
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.081
actin filament based process GO:0030029 86 0.081
Fly
regulation of hormone levels GO:0010817 187 0.081
regulation of potassium ion transport GO:0043266 29 0.080
regulation of anatomical structure size GO:0090066 135 0.080
regulation of defense response GO:0031347 68 0.080
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.079
gonad development GO:0008406 104 0.079
response to peptide hormone GO:0043434 278 0.078
Fly
endocytosis GO:0006897 84 0.077
negative regulation of nucleic acid templated transcription GO:1903507 117 0.077
cellular response to insulin stimulus GO:0032869 81 0.077
Fly
positive regulation of immune system process GO:0002684 90 0.077
Mouse Rat
regulation of neuron apoptotic process GO:0043523 83 0.077
purine ribonucleotide biosynthetic process GO:0009152 81 0.077
kidney morphogenesis GO:0060993 13 0.077
Rat
cell adhesion GO:0007155 110 0.076
response to glucose GO:0009749 136 0.076
positive regulation of cellular component movement GO:0051272 102 0.076
ribonucleoside triphosphate catabolic process GO:0009203 122 0.076
fatty acid metabolic process GO:0006631 99 0.075
response to metal ion GO:0010038 253 0.074
sensory perception of pain GO:0019233 73 0.073
regulation of blood pressure GO:0008217 83 0.073
glial cell differentiation GO:0010001 65 0.073
positive regulation of gene expression GO:0010628 244 0.073
negative regulation of signaling GO:0023057 157 0.072
cellular amino acid metabolic process GO:0006520 107 0.072
mesenchymal cell proliferation GO:0010463 4 0.071
cellular ion homeostasis GO:0006873 184 0.071
nucleotide biosynthetic process GO:0009165 98 0.071
response to hexose GO:0009746 144 0.070
monosaccharide metabolic process GO:0005996 61 0.070
regulation of protein modification process GO:0031399 194 0.070
response to blue light GO:0009637 1 0.070
intracellular transport GO:0046907 185 0.070
carbohydrate metabolic process GO:0005975 130 0.070
negative regulation of secretion by cell GO:1903531 72 0.070
regulation of catalytic activity GO:0050790 304 0.070
regulation of peptide transport GO:0090087 87 0.069
regulation of cell activation GO:0050865 50 0.069
Rat
response to transforming growth factor beta GO:0071559 46 0.069
male mating behavior GO:0060179 3 0.069
positive regulation of cellular component organization GO:0051130 200 0.069
embryo development GO:0009790 49 0.069
Mouse Fly
heart process GO:0003015 57 0.068
Zebrafish
membrane organization GO:0061024 94 0.068
reproductive system development GO:0061458 128 0.067
Fly
positive regulation of protein metabolic process GO:0051247 178 0.067
olfactory bulb interneuron differentiation GO:0021889 1 0.067
negative regulation of calcium ion transport GO:0051926 14 0.067
neuron death GO:0070997 127 0.066
single organism organelle organization GO:1902589 180 0.066
Fly
nitrogen compound transport GO:0071705 229 0.066
protein oligomerization GO:0051259 191 0.066
cyclic purine nucleotide metabolic process GO:0052652 62 0.066
kidney epithelium development GO:0072073 19 0.066
t cell activation GO:0042110 29 0.065
Rat
oxidation reduction process GO:0055114 304 0.065
monovalent inorganic cation transport GO:0015672 172 0.065
nucleoside phosphate catabolic process GO:1901292 140 0.064
organophosphate catabolic process GO:0046434 148 0.064
regulation of tube size GO:0035150 89 0.064
rhythmic process GO:0048511 156 0.064
reactive oxygen species metabolic process GO:0072593 37 0.064
purine nucleotide biosynthetic process GO:0006164 83 0.063
branching morphogenesis of an epithelial tube GO:0048754 14 0.063
Mouse
organ formation GO:0048645 3 0.063
sequestering of calcium ion GO:0051208 8 0.063
purine containing compound biosynthetic process GO:0072522 85 0.063
positive regulation of nervous system development GO:0051962 178 0.063
negative regulation of cell communication GO:0010648 158 0.062
t cell homeostasis GO:0043029 2 0.062
skeletal muscle tissue development GO:0007519 31 0.061
Rat
negative regulation of signal transduction GO:0009968 83 0.061
transcription dna templated GO:0006351 377 0.061
neuron projection development GO:0031175 273 0.061
sodium ion transmembrane transport GO:0035725 67 0.061
response to insulin GO:0032868 133 0.060
Fly
regulation of metanephros development GO:0072215 4 0.060
positive regulation of mapk cascade GO:0043410 92 0.060
cellular response to lipopolysaccharide GO:0071222 55 0.060
regulation of cellular amino acid metabolic process GO:0006521 2 0.060
cellular response to alcohol GO:0097306 87 0.059
single organism biosynthetic process GO:0044711 342 0.059
Rat
macromolecule localization GO:0033036 252 0.059
negative regulation of gene expression GO:0010629 199 0.059
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.059
cellular amine metabolic process GO:0044106 38 0.058
signal release GO:0023061 145 0.058
ribonucleotide biosynthetic process GO:0009260 85 0.058
ribonucleoside triphosphate metabolic process GO:0009199 141 0.058
cellular response to hexose stimulus GO:0071331 65 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.057
cellular response to reactive oxygen species GO:0034614 55 0.057
purine nucleoside metabolic process GO:0042278 169 0.057
regulation of fat cell differentiation GO:0045598 3 0.057
multi organism reproductive process GO:0044703 262 0.057
Fly
cytosolic calcium ion transport GO:0060401 39 0.057
organophosphate biosynthetic process GO:0090407 143 0.056
germline stem cell asymmetric division GO:0098728 1 0.056
purinergic receptor signaling pathway GO:0035587 10 0.056
negative regulation of ion transport GO:0043271 51 0.056
cellular component biogenesis GO:0044085 368 0.056
Fly
cell projection morphogenesis GO:0048858 123 0.056
negative regulation of rna biosynthetic process GO:1902679 118 0.055
axonogenesis GO:0007409 71 0.055
neuronal action potential GO:0019228 35 0.054
response to acid chemical GO:0001101 222 0.054
Rat
embryonic cranial skeleton morphogenesis GO:0048701 2 0.054
action potential GO:0001508 54 0.054
tissue morphogenesis GO:0048729 22 0.054
Mouse Fly
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.054
homeostasis of number of cells GO:0048872 10 0.054
Rat Fly
tissue remodeling GO:0048771 40 0.054
Rat
regulation of cell morphogenesis GO:0022604 77 0.053
Fly
positive regulation of neural precursor cell proliferation GO:2000179 10 0.053
developmental growth GO:0048589 100 0.053
biological adhesion GO:0022610 110 0.053
purine ribonucleoside metabolic process GO:0046128 168 0.053
anterior posterior pattern specification GO:0009952 1 0.053
gamete generation GO:0007276 124 0.052
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.052
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.052
macromolecular complex subunit organization GO:0043933 339 0.051
Fly
multicellular organism growth GO:0035264 1 0.051
response to lipopolysaccharide GO:0032496 191 0.051
negative regulation of amine transport GO:0051953 24 0.051
regulation of mapk cascade GO:0043408 116 0.051
positive regulation of cell proliferation GO:0008284 249 0.050
retina morphogenesis in camera type eye GO:0060042 1 0.050
activation of protein kinase activity GO:0032147 47 0.050
phenol containing compound metabolic process GO:0018958 30 0.050
phototransduction visible light GO:0007603 2 0.049
positive regulation of metanephros development GO:0072216 2 0.049
positive regulation of ion transport GO:0043270 94 0.049
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.049
Human
ribonucleotide catabolic process GO:0009261 136 0.049
morphogenesis of an epithelium GO:0002009 20 0.049
Mouse Fly
negative regulation of metabolic process GO:0009892 331 0.049
regulation of neuron death GO:1901214 115 0.049
adult behavior GO:0030534 16 0.049
hormone secretion GO:0046879 115 0.049
stem cell maintenance GO:0019827 6 0.048
carbohydrate derivative catabolic process GO:1901136 147 0.048
vasodilation GO:0042311 44 0.048
regulation of neural precursor cell proliferation GO:2000177 16 0.048
epithelial cell migration GO:0010631 19 0.048
Fly
brain development GO:0007420 247 0.048
negative regulation of calcium ion import GO:0090281 2 0.047
peptide transport GO:0015833 97 0.047
striated muscle contraction GO:0006941 44 0.047
response to electrical stimulus GO:0051602 56 0.047
regulation of cellular response to growth factor stimulus GO:0090287 15 0.047
Human
spindle organization GO:0007051 2 0.047
Fly
head development GO:0060322 247 0.047
peptide secretion GO:0002790 86 0.046
positive regulation of nucleoside metabolic process GO:0045979 55 0.046
positive regulation of cellular protein metabolic process GO:0032270 167 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
Rat
negative regulation of secretion GO:0051048 82 0.046
regulation of secretion by cell GO:1903530 208 0.046
negative regulation of neuron apoptotic process GO:0043524 45 0.046
cell chemotaxis GO:0060326 31 0.046
Human
amine metabolic process GO:0009308 38 0.046
positive regulation of cellular amine metabolic process GO:0033240 3 0.046
regulation of nervous system development GO:0051960 264 0.045
glucose homeostasis GO:0042593 75 0.045
transmission of nerve impulse GO:0019226 42 0.045
cellular response to tumor necrosis factor GO:0071356 46 0.045
endothelial cell morphogenesis GO:0001886 1 0.045
ovulation cycle GO:0042698 67 0.045
regulation of dendrite development GO:0050773 59 0.045
coronary vasculature morphogenesis GO:0060977 3 0.045
inorganic ion transmembrane transport GO:0098660 229 0.045
positive regulation of developmental process GO:0051094 283 0.045
Human Mouse Rat
locomotor rhythm GO:0045475 1 0.044
organic cyclic compound catabolic process GO:1901361 175 0.044
hormone transport GO:0009914 121 0.044
regulation of response to stress GO:0080134 126 0.044
response to extracellular stimulus GO:0009991 380 0.044
positive regulation of inflammatory response GO:0050729 24 0.044
response to nutrient levels GO:0031667 370 0.044
carbohydrate homeostasis GO:0033500 75 0.044
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.044
gastrulation GO:0007369 2 0.043
apoptotic signaling pathway GO:0097190 27 0.043
defecation GO:0030421 1 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
dephosphorylation GO:0016311 98 0.043
activation of mapkk activity GO:0000186 18 0.043

Flt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.211
vascular disease DOID:178 0 0.211
cardiovascular system disease DOID:1287 0 0.211
nervous system disease DOID:863 0 0.099
central nervous system disease DOID:331 0 0.046
hypertension DOID:10763 0 0.045
artery disease DOID:0050828 0 0.045