Rattus norvegicus

0 known processes

Foxc2

forkhead box C2

(Aliases: Fkhl14,Fkh14,Hfhbf3)

Foxc2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.371
neuron differentiation GO:0030182 368 0.305
neuron development GO:0048666 286 0.260
cell projection organization GO:0030030 302 0.245
developmental induction GO:0031128 2 0.209
regulation of rna metabolic process GO:0051252 391 0.196
cell part morphogenesis GO:0032990 123 0.196
anatomical structure morphogenesis GO:0009653 298 0.176
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.168
transcription from rna polymerase ii promoter GO:0006366 252 0.153
neuron projection development GO:0031175 273 0.145
cell projection morphogenesis GO:0048858 123 0.133
regulation of transcription dna templated GO:0006355 374 0.130
positive regulation of gene expression GO:0010628 244 0.123
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.122
sympathetic nervous system development GO:0048485 1 0.117
rna biosynthetic process GO:0032774 380 0.112
regulation of rna biosynthetic process GO:2001141 381 0.106
transcription dna templated GO:0006351 377 0.104
positive regulation of nucleic acid templated transcription GO:1903508 197 0.104
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.104
embryonic skeletal system morphogenesis GO:0048704 3 0.102
regulation of phosphorus metabolic process GO:0051174 349 0.101
parasympathetic nervous system development GO:0048486 1 0.098
negative regulation of metabolic process GO:0009892 331 0.095
neuron projection morphogenesis GO:0048812 122 0.094
rna metabolic process GO:0016070 406 0.094
negative regulation of biosynthetic process GO:0009890 168 0.091
regulation of multicellular organismal development GO:2000026 376 0.086
positive regulation of response to stimulus GO:0048584 285 0.086
tissue development GO:0009888 252 0.086
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.086
gland development GO:0048732 155 0.086
negative regulation of nervous system development GO:0051961 79 0.082
regulation of cellular amino acid metabolic process GO:0006521 2 0.082
negative regulation of macromolecule metabolic process GO:0010605 260 0.080
positive regulation of signal transduction GO:0009967 175 0.080
embryonic cranial skeleton morphogenesis GO:0048701 2 0.074
regulation of phosphorylation GO:0042325 248 0.070
cellular response to endogenous stimulus GO:0071495 377 0.068
embryonic skeletal system development GO:0048706 3 0.068
motor neuron axon guidance GO:0008045 1 0.068
enzyme linked receptor protein signaling pathway GO:0007167 116 0.063
axon guidance GO:0007411 24 0.062
positive regulation of transcription dna templated GO:0045893 197 0.062
gastrulation GO:0007369 2 0.061
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.061
head development GO:0060322 247 0.061
mesoderm development GO:0007498 2 0.059
regulation of cell projection organization GO:0031344 175 0.058
formation of primary germ layer GO:0001704 1 0.058
anterior posterior pattern specification GO:0009952 1 0.057
negative regulation of gene expression GO:0010629 199 0.057
positive regulation of tolerance induction GO:0002645 1 0.056
response to nutrient levels GO:0031667 370 0.056
regulation of neuron projection development GO:0010975 161 0.056
response to growth factor GO:0070848 189 0.055
cell type specific apoptotic process GO:0097285 134 0.055
regulation of organ formation GO:0003156 2 0.055
locomotion GO:0040011 237 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
negative regulation of molecular function GO:0044092 133 0.053
embryo development GO:0009790 49 0.052
regulation of signal transduction GO:0009966 318 0.051
sex differentiation GO:0007548 113 0.051
regulation of tolerance induction to nonself antigen GO:0002655 1 0.051
positive regulation of cell projection organization GO:0031346 111 0.051
regulation of anatomical structure morphogenesis GO:0022603 141 0.051
positive regulation of biosynthetic process GO:0009891 319 0.049
organ formation GO:0048645 3 0.049
cellular ketone metabolic process GO:0042180 51 0.048
negative regulation of cellular component organization GO:0051129 83 0.048
regulation of intracellular signal transduction GO:1902531 218 0.047
cellular response to external stimulus GO:0071496 118 0.047
embryonic pattern specification GO:0009880 1 0.045
multicellular organismal reproductive process GO:0048609 233 0.045
cellular amino acid metabolic process GO:0006520 107 0.045
cellular response to growth factor stimulus GO:0071363 162 0.044
regulation of cellular ketone metabolic process GO:0010565 27 0.044
regulation of nervous system development GO:0051960 264 0.043
positive regulation of cell communication GO:0010647 271 0.043
regulation of bmp signaling pathway GO:0030510 2 0.042
response to extracellular stimulus GO:0009991 380 0.042
brain development GO:0007420 247 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
negative regulation of rna metabolic process GO:0051253 123 0.041
negative regulation of cell development GO:0010721 82 0.040
positive regulation of protein phosphorylation GO:0001934 135 0.040
regulation of molecular function GO:0065009 398 0.040
tissue morphogenesis GO:0048729 22 0.040
positive regulation of developmental process GO:0051094 283 0.039
t cell tolerance induction GO:0002517 3 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
programmed cell death GO:0012501 392 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
regulation of cell development GO:0060284 263 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
digestive tract development GO:0048565 39 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.035
negative regulation of neuron differentiation GO:0045665 62 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
amine metabolic process GO:0009308 38 0.035
nucleic acid templated transcription GO:0097659 379 0.034
bmp signaling pathway GO:0030509 4 0.034
organophosphate metabolic process GO:0019637 370 0.034
anatomical structure formation involved in morphogenesis GO:0048646 83 0.034
nucleoside metabolic process GO:0009116 179 0.034
tube development GO:0035295 89 0.033
developmental process involved in reproduction GO:0003006 159 0.033
negative regulation of growth GO:0045926 37 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
negative regulation of developmental process GO:0051093 125 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.032
cerebral cortex tangential migration GO:0021800 1 0.032
cellular component morphogenesis GO:0032989 155 0.032
negative regulation of transcription dna templated GO:0045892 116 0.032
response to nutrient GO:0007584 248 0.030
forebrain development GO:0030900 98 0.030
cellular response to stress GO:0033554 269 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
multicellular organism reproduction GO:0032504 233 0.029
neuron projection guidance GO:0097485 24 0.029
regulation of neuron differentiation GO:0045664 208 0.029
reproductive structure development GO:0048608 128 0.029
tolerance induction dependent upon immune response GO:0002461 2 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
cellular response to oxygen containing compound GO:1901701 386 0.028
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.028
eye morphogenesis GO:0048592 4 0.028
regulation of mapk cascade GO:0043408 116 0.028
metanephric part of ureteric bud development GO:0035502 1 0.028
regulation of peptide transport GO:0090087 87 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
negative regulation of neurogenesis GO:0050768 78 0.027
secretion GO:0046903 307 0.027
sensory organ development GO:0007423 74 0.026
cellular amine metabolic process GO:0044106 38 0.026
neuron apoptotic process GO:0051402 88 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
mesoderm morphogenesis GO:0048332 1 0.026
reproductive process GO:0022414 372 0.025
reproduction GO:0000003 245 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
metanephric comma shaped body morphogenesis GO:0072278 2 0.025
cell cell signaling GO:0007267 335 0.025
cellular component movement GO:0006928 248 0.025
organ induction GO:0001759 1 0.024
regulation of cell differentiation GO:0045595 320 0.024
erythrocyte differentiation GO:0030218 1 0.024
salivary gland development GO:0007431 3 0.024
positive regulation of neuron projection development GO:0010976 99 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
positive regulation of nervous system development GO:0051962 178 0.023
response to other organism GO:0051707 220 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
regulation of neurogenesis GO:0050767 247 0.022
peptide secretion GO:0002790 86 0.022
dendrite development GO:0016358 72 0.022
axon development GO:0061564 96 0.022
olfactory bulb interneuron differentiation GO:0021889 1 0.022
chemotaxis GO:0006935 66 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
oxoacid metabolic process GO:0043436 290 0.022
regulation of protein metabolic process GO:0051246 289 0.021
specification of organ identity GO:0010092 2 0.021
autonomic nervous system development GO:0048483 3 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 1 0.021
cellular component assembly GO:0022607 360 0.021
dephosphorylation GO:0016311 98 0.021
single organism reproductive process GO:0044702 297 0.021
mesoderm formation GO:0001707 1 0.021
glial cell differentiation GO:0010001 65 0.021
osteoblast differentiation GO:0001649 26 0.020
protein phosphorylation GO:0006468 345 0.020
cell fate determination GO:0001709 2 0.020
cellular protein localization GO:0034613 122 0.020
spinal cord development GO:0021510 27 0.020
female gonad development GO:0008585 53 0.019
intracellular signal transduction GO:0035556 314 0.019
hepatocyte differentiation GO:0070365 8 0.019
hormone secretion GO:0046879 115 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
mesonephros development GO:0001823 14 0.019
central nervous system development GO:0007417 311 0.019
adult locomotory behavior GO:0008344 4 0.019
response to bacterium GO:0009617 200 0.018
neural crest cell development GO:0014032 2 0.018
axonogenesis GO:0007409 71 0.018
gliogenesis GO:0042063 93 0.018
regulation of cellular component organization GO:0051128 368 0.018
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.018
development of primary sexual characteristics GO:0045137 107 0.018
forebrain generation of neurons GO:0021872 8 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
nucleotide metabolic process GO:0009117 279 0.018
neuron death GO:0070997 127 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of activation of jak2 kinase activity GO:0010534 1 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.017
positive regulation of cell death GO:0010942 184 0.017
digestive system development GO:0055123 41 0.016
regeneration GO:0031099 163 0.016
camera type eye morphogenesis GO:0048593 2 0.016
response to cytokine GO:0034097 215 0.016
response to inorganic substance GO:0010035 377 0.016
negative regulation of signal transduction GO:0009968 83 0.016
macromolecule localization GO:0033036 252 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
male sex differentiation GO:0046661 64 0.016
camera type eye development GO:0043010 48 0.016
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.016
response to hypoxia GO:0001666 231 0.016
positive regulation of biomineral tissue development GO:0070169 4 0.016
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.016
cerebellar cortex formation GO:0021697 2 0.016
palate development GO:0060021 2 0.015
muscle system process GO:0003012 115 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of membrane potential GO:0042391 110 0.015
response to retinoic acid GO:0032526 63 0.015
eye development GO:0001654 50 0.015
muscle structure development GO:0061061 87 0.015
organelle organization GO:0006996 266 0.015
hepaticobiliary system development GO:0061008 90 0.015
response to vitamin GO:0033273 131 0.015
s shaped body morphogenesis GO:0072050 2 0.015
hindbrain morphogenesis GO:0021575 2 0.015
negative regulation of cell death GO:0060548 229 0.015
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.015
regulation of growth GO:0040008 105 0.014
cellular lipid metabolic process GO:0044255 208 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
single organism cellular localization GO:1902580 102 0.014
response to mechanical stimulus GO:0009612 134 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
retina development in camera type eye GO:0060041 27 0.014
response to estradiol GO:0032355 164 0.014
tolerance induction to nonself antigen GO:0002462 2 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of fat cell proliferation GO:0070346 1 0.014
protein localization GO:0008104 191 0.014
circulatory system development GO:0072359 134 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
axis specification GO:0009798 4 0.014
regulation of gluconeogenesis GO:0006111 4 0.014
response to monosaccharide GO:0034284 159 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
organic acid metabolic process GO:0006082 292 0.013
regulation of dendrite morphogenesis GO:0048814 33 0.013
regulation of tolerance induction GO:0002643 2 0.013
neuronal stem cell maintenance GO:0097150 2 0.013
telencephalon development GO:0021537 62 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
cardiac chamber development GO:0003205 1 0.013
lipid metabolic process GO:0006629 283 0.013
regulation of response to stress GO:0080134 126 0.013
positive regulation of hepatocyte differentiation GO:0070368 2 0.013
regulation of programmed cell death GO:0043067 341 0.013
macromolecular complex assembly GO:0065003 273 0.013
preganglionic parasympathetic nervous system development GO:0021783 1 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.013
regulation of brown fat cell proliferation GO:0070347 1 0.013
regulation of cell proliferation GO:0042127 359 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
cardiac ventricle development GO:0003231 1 0.013
dendrite morphogenesis GO:0048813 43 0.012
cerebral cortex cell migration GO:0021795 4 0.012
glomerular mesangial cell proliferation GO:0072110 4 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
protein complex biogenesis GO:0070271 263 0.012
apoptotic process GO:0006915 381 0.012
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 5 0.012
response to oxygen levels GO:0070482 265 0.012
neural crest cell migration GO:0001755 1 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
nuclear import GO:0051170 35 0.012
gamete generation GO:0007276 124 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
cellular response to alcohol GO:0097306 87 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
positive regulation of signaling GO:0023056 270 0.012
ureteric bud development GO:0001657 14 0.012
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.012
regulation of osteoblast differentiation GO:0045667 14 0.012
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.012
epithelial cell differentiation GO:0030855 71 0.012
regulation of kinase activity GO:0043549 117 0.012
skeletal system development GO:0001501 41 0.012
intracellular protein transport GO:0006886 79 0.012
chordate embryonic development GO:0043009 18 0.011
microvillus assembly GO:0030033 2 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
reproductive system development GO:0061458 128 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
immune system development GO:0002520 41 0.011
erythrocyte homeostasis GO:0034101 2 0.011
organ morphogenesis GO:0009887 75 0.011
epithelium development GO:0060429 96 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
angiogenesis GO:0001525 53 0.011
blood vessel development GO:0001568 69 0.011
ovulation cycle GO:0042698 67 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of apoptotic process GO:0042981 335 0.011
tube morphogenesis GO:0035239 23 0.011
response to testosterone GO:0033574 55 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.011
embryonic axis specification GO:0000578 1 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
protein heterooligomerization GO:0051291 89 0.011
protein oligomerization GO:0051259 191 0.011
cell morphogenesis GO:0000902 142 0.010
blood vessel morphogenesis GO:0048514 58 0.010
glutamate receptor signaling pathway GO:0007215 43 0.010
protein complex assembly GO:0006461 263 0.010
regulation of protein modification process GO:0031399 194 0.010
molting cycle GO:0042303 3 0.010
stem cell differentiation GO:0048863 16 0.010
muscle tissue development GO:0060537 58 0.010
response to acid chemical GO:0001101 222 0.010
gonad development GO:0008406 104 0.010
negative regulation of cell communication GO:0010648 158 0.010
urogenital system development GO:0001655 78 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
negative regulation of cell growth GO:0030308 33 0.010
regulation of axon extension GO:0030516 24 0.010
regulation of fat cell proliferation GO:0070344 1 0.010
negative regulation of signaling GO:0023057 157 0.010
response to corticosteroid GO:0031960 235 0.010

Foxc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of cellular proliferation DOID:14566 0 0.016
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010
metal metabolism disorder DOID:896 0 0.010