Rattus norvegicus

0 known processes

Foxd4

forkhead box D4

Foxd4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dorsal ventral axon guidance GO:0033563 1 0.266
axon choice point recognition GO:0016198 2 0.177
oxoacid metabolic process GO:0043436 290 0.154
female gonad development GO:0008585 53 0.150
axon midline choice point recognition GO:0016199 2 0.149
positive regulation of multicellular organismal process GO:0051240 387 0.137
transcription dna templated GO:0006351 377 0.124
organic acid metabolic process GO:0006082 292 0.117
mesoderm development GO:0007498 2 0.105
central nervous system development GO:0007417 311 0.105
carboxylic acid metabolic process GO:0019752 289 0.102
development of primary sexual characteristics GO:0045137 107 0.101
programmed cell death GO:0012501 392 0.090
negative regulation of gene expression GO:0010629 199 0.071
transcription from rna polymerase ii promoter GO:0006366 252 0.070
cellular amino acid metabolic process GO:0006520 107 0.070
head development GO:0060322 247 0.067
regulation of cellular ketone metabolic process GO:0010565 27 0.067
amine metabolic process GO:0009308 38 0.064
cell projection organization GO:0030030 302 0.063
negative regulation of metabolic process GO:0009892 331 0.063
reproductive system development GO:0061458 128 0.063
cellular response to endogenous stimulus GO:0071495 377 0.062
cellular catabolic process GO:0044248 295 0.059
regulation of hormone levels GO:0010817 187 0.058
skeletal system development GO:0001501 41 0.058
rna biosynthetic process GO:0032774 380 0.057
neuron projection development GO:0031175 273 0.057
anatomical structure morphogenesis GO:0009653 298 0.057
positive regulation of developmental process GO:0051094 283 0.056
multicellular organism reproduction GO:0032504 233 0.055
reproductive structure development GO:0048608 128 0.051
negative regulation of cellular biosynthetic process GO:0031327 161 0.050
positive regulation of gene expression GO:0010628 244 0.050
response to nutrient levels GO:0031667 370 0.047
response to corticosteroid GO:0031960 235 0.047
nucleic acid templated transcription GO:0097659 379 0.045
response to oxidative stress GO:0006979 186 0.045
positive regulation of cell projection organization GO:0031346 111 0.045
heart morphogenesis GO:0003007 3 0.045
aging GO:0007568 241 0.044
negative regulation of programmed cell death GO:0043069 183 0.044
organ formation GO:0048645 3 0.044
male sex differentiation GO:0046661 64 0.043
cellular ketone metabolic process GO:0042180 51 0.043
small molecule biosynthetic process GO:0044283 124 0.043
regulation of multicellular organismal development GO:2000026 376 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
regulation of programmed cell death GO:0043067 341 0.040
protein complex biogenesis GO:0070271 263 0.040
chemical homeostasis GO:0048878 292 0.040
cellular component biogenesis GO:0044085 368 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
response to estrogen GO:0043627 232 0.039
tissue development GO:0009888 252 0.039
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
positive regulation of ion transport GO:0043270 94 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.038
response to extracellular stimulus GO:0009991 380 0.037
response to insulin GO:0032868 133 0.037
ovulation cycle process GO:0022602 50 0.037
negative regulation of rna metabolic process GO:0051253 123 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
cell morphogenesis involved in differentiation GO:0000904 119 0.037
cellular amine metabolic process GO:0044106 38 0.036
rna metabolic process GO:0016070 406 0.036
apoptotic process GO:0006915 381 0.036
protein heterooligomerization GO:0051291 89 0.035
gonad development GO:0008406 104 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
regulation of transcription dna templated GO:0006355 374 0.035
sex differentiation GO:0007548 113 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
protein complex subunit organization GO:0071822 302 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.034
neurological system process GO:0050877 219 0.034
single organism reproductive process GO:0044702 297 0.034
behavior GO:0007610 205 0.033
response to inorganic substance GO:0010035 377 0.033
regulation of cellular component organization GO:0051128 368 0.033
female sex differentiation GO:0046660 59 0.033
protein complex assembly GO:0006461 263 0.032
protein oligomerization GO:0051259 191 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
reproductive process GO:0022414 372 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.030
positive regulation of transcription dna templated GO:0045893 197 0.029
organophosphate metabolic process GO:0019637 370 0.028
protein autophosphorylation GO:0046777 66 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
macromolecular complex assembly GO:0065003 273 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
peptidyl tyrosine modification GO:0018212 72 0.028
response to estradiol GO:0032355 164 0.027
developmental process involved in reproduction GO:0003006 159 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
reproduction GO:0000003 245 0.026
embryonic neurocranium morphogenesis GO:0048702 2 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.026
regulation of cell differentiation GO:0045595 320 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
morphogenesis of embryonic epithelium GO:0016331 3 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
regulation of rna metabolic process GO:0051252 391 0.025
response to vitamin GO:0033273 131 0.025
embryo development GO:0009790 49 0.025
immune system process GO:0002376 204 0.025
nucleoside phosphate catabolic process GO:1901292 140 0.025
regulation of cell projection organization GO:0031344 175 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
response to axon injury GO:0048678 59 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
development of primary female sexual characteristics GO:0046545 56 0.024
organelle organization GO:0006996 266 0.024
negative regulation of transport GO:0051051 136 0.023
negative regulation of peptide hormone secretion GO:0090278 30 0.023
cellular carbohydrate metabolic process GO:0044262 72 0.023
response to glucocorticoid GO:0051384 223 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
response to nutrient GO:0007584 248 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
regulation of neuron death GO:1901214 115 0.022
forebrain development GO:0030900 98 0.022
positive regulation of transport GO:0051050 245 0.022
cellular ion homeostasis GO:0006873 184 0.022
neuron differentiation GO:0030182 368 0.022
cellular lipid metabolic process GO:0044255 208 0.021
single organism organelle organization GO:1902589 180 0.021
response to carbohydrate GO:0009743 183 0.021
cartilage development GO:0051216 22 0.021
regulation of apoptotic process GO:0042981 335 0.021
hemopoiesis GO:0030097 34 0.021
regulation of sister chromatid segregation GO:0033045 1 0.021
peptidyl amino acid modification GO:0018193 126 0.021
negative regulation of signaling GO:0023057 157 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
cellular response to stress GO:0033554 269 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
nucleotide metabolic process GO:0009117 279 0.020
secretion by cell GO:0032940 248 0.020
signal release GO:0023061 145 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
antral ovarian follicle growth GO:0001547 3 0.020
cardiac chamber development GO:0003205 1 0.020
brain development GO:0007420 247 0.020
dendrite development GO:0016358 72 0.020
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.020
membrane repolarization GO:0086009 1 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
purine containing compound metabolic process GO:0072521 253 0.019
sexual reproduction GO:0019953 148 0.019
negative regulation of nervous system development GO:0051961 79 0.019
regulation of neuron projection development GO:0010975 161 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
cellular component morphogenesis GO:0032989 155 0.019
response to hexose GO:0009746 144 0.019
heart process GO:0003015 57 0.018
cell cell signaling GO:0007267 335 0.018
ovulation cycle GO:0042698 67 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
single organism biosynthetic process GO:0044711 342 0.018
erythrocyte differentiation GO:0030218 1 0.018
positive regulation of cell development GO:0010720 176 0.018
blood circulation GO:0008015 183 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of lipid metabolic process GO:0019216 68 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
regulation of neurotransmitter uptake GO:0051580 1 0.018
actin filament based process GO:0030029 86 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.018
hexose metabolic process GO:0019318 58 0.017
cellular homeostasis GO:0019725 252 0.017
dna metabolic process GO:0006259 96 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
neuron development GO:0048666 286 0.017
detection of visible light GO:0009584 3 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of ion transport GO:0043269 245 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
peptide hormone secretion GO:0030072 84 0.017
organonitrogen compound catabolic process GO:1901565 179 0.016
response to temperature stimulus GO:0009266 94 0.016
hematopoietic or lymphoid organ development GO:0048534 36 0.016
neuron death GO:0070997 127 0.016
cellular response to reactive oxygen species GO:0034614 55 0.016
regulation of heart contraction GO:0008016 48 0.016
metal ion homeostasis GO:0055065 186 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
spinal cord development GO:0021510 27 0.016
cardiac conduction GO:0061337 2 0.016
multi organism reproductive process GO:0044703 262 0.015
gamete generation GO:0007276 124 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
sensory perception GO:0007600 101 0.015
cell communication involved in cardiac conduction GO:0086065 2 0.015
cellular response to vitamin e GO:0071306 3 0.015
epithelial cell differentiation GO:0030855 71 0.015
hormone secretion GO:0046879 115 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
dendrite morphogenesis GO:0048813 43 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
regulation of dendrite development GO:0050773 59 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
macromolecule localization GO:0033036 252 0.015
cellular response to oxidative stress GO:0034599 76 0.015
ion homeostasis GO:0050801 212 0.015
embryonic cranial skeleton morphogenesis GO:0048701 2 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
protein phosphorylation GO:0006468 345 0.015
organ induction GO:0001759 1 0.015
odontogenesis GO:0042476 32 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
tube formation GO:0035148 3 0.014
chromosome separation GO:0051304 1 0.014
connective tissue development GO:0061448 33 0.014
cardiac ventricle development GO:0003231 1 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
positive regulation of heart contraction GO:0045823 15 0.014
phototransduction visible light GO:0007603 2 0.014
cellular component assembly GO:0022607 360 0.014
detection of temperature stimulus GO:0016048 4 0.014
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
regulation of dna metabolic process GO:0051052 60 0.014
regulation of molecular function GO:0065009 398 0.014
actin cytoskeleton organization GO:0030036 73 0.014
positive regulation of molecular function GO:0044093 230 0.014
cerebellar purkinje cell differentiation GO:0021702 1 0.014
autophagy GO:0006914 19 0.014
steroid metabolic process GO:0008202 73 0.014
central nervous system neuron axonogenesis GO:0021955 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
adrenergic receptor signaling pathway GO:0071875 9 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
catabolic process GO:0009056 351 0.013
myeloid cell differentiation GO:0030099 22 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
response to peptide hormone GO:0043434 278 0.013
palate development GO:0060021 2 0.013
secretion GO:0046903 307 0.013
embryonic pattern specification GO:0009880 1 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
single organism catabolic process GO:0044712 283 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
negative regulation of cell projection organization GO:0031345 50 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of signal transduction GO:0009966 318 0.013
response to cytokine GO:0034097 215 0.013
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of exit from mitosis GO:0007096 1 0.012
response to glucose GO:0009749 136 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of mitotic sister chromatid separation GO:0010965 1 0.012
retinal ganglion cell axon guidance GO:0031290 1 0.012
motor neuron axon guidance GO:0008045 1 0.012
positive regulation of blood circulation GO:1903524 65 0.012
metanephric part of ureteric bud development GO:0035502 1 0.012
positive regulation of cell death GO:0010942 184 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to retinoic acid GO:0032526 63 0.012
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.012
multi organism behavior GO:0051705 24 0.012
cerebellar purkinje cell layer development GO:0021680 2 0.012
chromosome segregation GO:0007059 2 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
nucleoside metabolic process GO:0009116 179 0.012
antigen receptor mediated signaling pathway GO:0050851 1 0.012
gap junction assembly GO:0016264 2 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
immune system development GO:0002520 41 0.011
response to calcium ion GO:0051592 59 0.011
anion transport GO:0006820 178 0.011
membrane depolarization during action potential GO:0086010 1 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.011
heterocycle catabolic process GO:0046700 167 0.011
intracellular signal transduction GO:0035556 314 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
response to ketone GO:1901654 182 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
male gonad development GO:0008584 59 0.011
cellular chemical homeostasis GO:0055082 247 0.011
glucose homeostasis GO:0042593 75 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
membrane organization GO:0061024 94 0.011
cardiovascular system development GO:0072358 134 0.011
jak stat cascade GO:0007259 26 0.011
multi multicellular organism process GO:0044706 138 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
positive regulation of phosphorylation GO:0042327 177 0.010
behavioral response to nicotine GO:0035095 2 0.010
ovarian follicle development GO:0001541 31 0.010
regulation of neurogenesis GO:0050767 247 0.010
regulation of anion transport GO:0044070 43 0.010
gastrulation GO:0007369 2 0.010
embryonic skeletal system development GO:0048706 3 0.010
regulation of cellular localization GO:0060341 263 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
learning or memory GO:0007611 90 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
insulin receptor signaling pathway GO:0008286 24 0.010
male gamete generation GO:0048232 99 0.010
cation homeostasis GO:0055080 195 0.010
regulation of organelle organization GO:0033043 80 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
negative regulation of cell development GO:0010721 82 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
mrna transcription GO:0009299 2 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010

Foxd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.041
disease of anatomical entity DOID:7 0 0.041
cardiovascular system disease DOID:1287 0 0.018
heart conduction disease DOID:10273 0 0.018
familial atrial fibrillation DOID:0050650 0 0.018
central nervous system disease DOID:331 0 0.012