Rattus norvegicus

0 known processes

Frmd4b

FERM domain containing 4B

(Aliases: Grsp1,Nitzin)

Frmd4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.192
lipid metabolic process GO:0006629 283 0.141
lipid biosynthetic process GO:0008610 128 0.116
regulation of nervous system development GO:0051960 264 0.115
regulation of neurogenesis GO:0050767 247 0.104
response to peptide GO:1901652 292 0.102
cellular response to insulin stimulus GO:0032869 81 0.092
response to peptide hormone GO:0043434 278 0.088
organophosphate metabolic process GO:0019637 370 0.087
regulation of neuron differentiation GO:0045664 208 0.085
response to cytokine GO:0034097 215 0.084
regulation of signal transduction GO:0009966 318 0.083
organic substance catabolic process GO:1901575 316 0.079
cellular lipid metabolic process GO:0044255 208 0.077
intracellular signal transduction GO:0035556 314 0.073
secretion by cell GO:0032940 248 0.072
cellular response to endogenous stimulus GO:0071495 377 0.071
response to extracellular stimulus GO:0009991 380 0.067
regulation of cell development GO:0060284 263 0.067
cellular component movement GO:0006928 248 0.067
glycosyl compound metabolic process GO:1901657 182 0.067
regulation of molecular function GO:0065009 398 0.063
catabolic process GO:0009056 351 0.060
oxoacid metabolic process GO:0043436 290 0.059
transmembrane transport GO:0055085 412 0.058
epithelial cell differentiation involved in kidney development GO:0035850 3 0.057
regulation of multicellular organismal development GO:2000026 376 0.057
heart morphogenesis GO:0003007 3 0.052
regulation of mesenchymal cell proliferation GO:0010464 4 0.050
response to nutrient levels GO:0031667 370 0.049
cellular catabolic process GO:0044248 295 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
response to carbohydrate GO:0009743 183 0.046
cell projection organization GO:0030030 302 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
cell motility GO:0048870 202 0.043
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.042
cellular response to hormone stimulus GO:0032870 247 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
negative regulation of signaling GO:0023057 157 0.040
chemical homeostasis GO:0048878 292 0.040
neuron development GO:0048666 286 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
negative regulation of cell communication GO:0010648 158 0.040
multicellular organism reproduction GO:0032504 233 0.039
amine metabolic process GO:0009308 38 0.039
central nervous system development GO:0007417 311 0.039
response to ketone GO:1901654 182 0.038
nucleoside metabolic process GO:0009116 179 0.038
neurological system process GO:0050877 219 0.038
circulatory system process GO:0003013 183 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
regulation of neuron projection development GO:0010975 161 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
negative regulation of neuron differentiation GO:0045665 62 0.037
positive regulation of cellular component organization GO:0051130 200 0.037
regulation of cell differentiation GO:0045595 320 0.037
regulation of cell projection organization GO:0031344 175 0.036
response to insulin GO:0032868 133 0.036
organic acid metabolic process GO:0006082 292 0.036
positive regulation of gene expression GO:0010628 244 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
positive regulation of transport GO:0051050 245 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.035
ribonucleoside triphosphate metabolic process GO:0009199 141 0.035
positive regulation of nervous system development GO:0051962 178 0.035
gland development GO:0048732 155 0.035
cellular component biogenesis GO:0044085 368 0.034
reproductive process GO:0022414 372 0.034
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.034
cellular response to peptide hormone stimulus GO:0071375 120 0.034
single organism organelle organization GO:1902589 180 0.034
cation transport GO:0006812 382 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.033
cellular response to peptide GO:1901653 133 0.032
cellular amine metabolic process GO:0044106 38 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
blood circulation GO:0008015 183 0.032
monovalent inorganic cation transport GO:0015672 172 0.032
mesenchymal cell proliferation GO:0010463 4 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
carbohydrate metabolic process GO:0005975 130 0.032
brain development GO:0007420 247 0.032
steroid biosynthetic process GO:0006694 48 0.032
ribonucleoside metabolic process GO:0009119 174 0.031
cellular calcium ion homeostasis GO:0006874 160 0.031
negative regulation of cell development GO:0010721 82 0.031
positive regulation of cell communication GO:0010647 271 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
neuron projection development GO:0031175 273 0.030
purine nucleoside metabolic process GO:0042278 169 0.030
single organism reproductive process GO:0044702 297 0.030
cellular component morphogenesis GO:0032989 155 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
response to inorganic substance GO:0010035 377 0.029
cell cell signaling GO:0007267 335 0.029
cellular response to organonitrogen compound GO:0071417 197 0.029
single organism carbohydrate metabolic process GO:0044723 118 0.029
cell differentiation involved in kidney development GO:0061005 4 0.029
small molecule biosynthetic process GO:0044283 124 0.028
ion homeostasis GO:0050801 212 0.028
response to acid chemical GO:0001101 222 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
programmed cell death GO:0012501 392 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
organelle organization GO:0006996 266 0.028
regulation of protein metabolic process GO:0051246 289 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.027
reproduction GO:0000003 245 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
multi organism reproductive process GO:0044703 262 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
rna biosynthetic process GO:0032774 380 0.026
metal ion homeostasis GO:0055065 186 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
positive regulation of locomotion GO:0040017 102 0.026
defense response GO:0006952 194 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
protein phosphorylation GO:0006468 345 0.026
cellular ion homeostasis GO:0006873 184 0.026
regulation of cell proliferation GO:0042127 359 0.026
regulation of transcription dna templated GO:0006355 374 0.025
cell part morphogenesis GO:0032990 123 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
regulation of rna metabolic process GO:0051252 391 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
locomotion GO:0040011 237 0.025
rna metabolic process GO:0016070 406 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
response to corticosteroid GO:0031960 235 0.024
cellular ketone metabolic process GO:0042180 51 0.024
cardiac chamber development GO:0003205 1 0.024
regeneration GO:0031099 163 0.024
response to growth factor GO:0070848 189 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
action potential GO:0001508 54 0.023
behavior GO:0007610 205 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
aromatic compound catabolic process GO:0019439 168 0.023
positive regulation of developmental process GO:0051094 283 0.023
cellular metal ion homeostasis GO:0006875 172 0.023
response to nutrient GO:0007584 248 0.023
protein complex subunit organization GO:0071822 302 0.023
neuron differentiation GO:0030182 368 0.023
regulation of secretion GO:0051046 224 0.023
response to monosaccharide GO:0034284 159 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
reproductive system development GO:0061458 128 0.023
neuron projection morphogenesis GO:0048812 122 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
learning GO:0007612 33 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
cell projection morphogenesis GO:0048858 123 0.022
regulation of protein modification process GO:0031399 194 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
eye morphogenesis GO:0048592 4 0.022
multi multicellular organism process GO:0044706 138 0.022
single organism catabolic process GO:0044712 283 0.022
regulation of catalytic activity GO:0050790 304 0.022
response to glucose GO:0009749 136 0.022
ion transmembrane transport GO:0034220 365 0.022
rhythmic process GO:0048511 156 0.021
protein oligomerization GO:0051259 191 0.021
homeostatic process GO:0042592 331 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
actin filament based process GO:0030029 86 0.021
cognition GO:0050890 92 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
cell migration GO:0016477 197 0.021
secretion GO:0046903 307 0.021
gonad development GO:0008406 104 0.021
response to oxidative stress GO:0006979 186 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
cellular chemical homeostasis GO:0055082 247 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.020
nucleic acid templated transcription GO:0097659 379 0.020
cell morphogenesis GO:0000902 142 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of defense response GO:0031349 37 0.020
jak stat cascade GO:0007259 26 0.020
positive regulation of cell development GO:0010720 176 0.020
negative regulation of transport GO:0051051 136 0.020
steroid metabolic process GO:0008202 73 0.020
negative regulation of metabolic process GO:0009892 331 0.020
positive regulation of signal transduction GO:0009967 175 0.020
kidney development GO:0001822 67 0.020
nucleotide catabolic process GO:0009166 139 0.020
response to hexose GO:0009746 144 0.020
peptidyl amino acid modification GO:0018193 126 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
cellular response to oxygen containing compound GO:1901701 386 0.019
cellular component assembly GO:0022607 360 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
nucleoside catabolic process GO:0009164 126 0.019
organophosphate catabolic process GO:0046434 148 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
response to reactive oxygen species GO:0000302 120 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
response to vitamin GO:0033273 131 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
tissue development GO:0009888 252 0.019
anion transport GO:0006820 178 0.019
negative regulation of nervous system development GO:0051961 79 0.019
cellular response to stress GO:0033554 269 0.019
neuronal action potential GO:0019228 35 0.019
regulation of cellular component movement GO:0051270 150 0.019
negative regulation of signal transduction GO:0009968 83 0.019
sexual reproduction GO:0019953 148 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
regulation of ion transport GO:0043269 245 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
cytoskeleton organization GO:0007010 111 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
regulation of cellular component organization GO:0051128 368 0.018
regulation of locomotion GO:0040012 148 0.018
regulation of membrane potential GO:0042391 110 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
dna metabolic process GO:0006259 96 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
axon development GO:0061564 96 0.017
regulation of catabolic process GO:0009894 113 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
organ regeneration GO:0031100 101 0.017
biological adhesion GO:0022610 110 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
localization of cell GO:0051674 202 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
ras protein signal transduction GO:0007265 29 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
axis specification GO:0009798 4 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
protein maturation GO:0051604 68 0.017
head development GO:0060322 247 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
apoptotic process GO:0006915 381 0.017
positive regulation of cell death GO:0010942 184 0.017
positive regulation of signaling GO:0023056 270 0.016
regulation of transmembrane transport GO:0034762 122 0.016
multicellular organism growth GO:0035264 1 0.016
organ induction GO:0001759 1 0.016
regulation of organ formation GO:0003156 2 0.016
protein processing GO:0016485 68 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
sodium ion transport GO:0006814 82 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
response to ionizing radiation GO:0010212 59 0.016
response to oxygen levels GO:0070482 265 0.016
neuron projection guidance GO:0097485 24 0.016
regulation of cell migration GO:0030334 128 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
cardiac ventricle development GO:0003231 1 0.016
inflammatory response GO:0006954 150 0.016
positive regulation of molecular function GO:0044093 230 0.016
regulation of growth GO:0040008 105 0.016
synaptic transmission GO:0007268 235 0.016
transcription dna templated GO:0006351 377 0.016
epithelium development GO:0060429 96 0.016
regulation of phosphorylation GO:0042325 248 0.016
negative regulation of secretion GO:0051048 82 0.015
glycerolipid metabolic process GO:0046486 67 0.015
muscle cell proliferation GO:0033002 84 0.015
regulation of apoptotic process GO:0042981 335 0.015
positive regulation of cell migration GO:0030335 96 0.015
development of primary sexual characteristics GO:0045137 107 0.015
heart development GO:0007507 72 0.015
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
transmission of nerve impulse GO:0019226 42 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
response to other organism GO:0051707 220 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
gastrulation GO:0007369 2 0.015
reproductive structure development GO:0048608 128 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
regulation of neural precursor cell proliferation GO:2000177 16 0.015
oxidation reduction process GO:0055114 304 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
calcium ion homeostasis GO:0055074 162 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of cellular localization GO:0060341 263 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
gliogenesis GO:0042063 93 0.015
cellular homeostasis GO:0019725 252 0.014
response to organophosphorus GO:0046683 102 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
camera type eye morphogenesis GO:0048593 2 0.014
telencephalon development GO:0021537 62 0.014
phospholipid metabolic process GO:0006644 61 0.014
response to estrogen GO:0043627 232 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
pallium development GO:0021543 42 0.014
hepaticobiliary system development GO:0061008 90 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
neural precursor cell proliferation GO:0061351 23 0.014
response to mechanical stimulus GO:0009612 134 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
single organism behavior GO:0044708 130 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
developmental induction GO:0031128 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
ossification GO:0001503 70 0.014
response to fibroblast growth factor GO:0071774 29 0.013
response to purine containing compound GO:0014074 126 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
monosaccharide metabolic process GO:0005996 61 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cellular cation homeostasis GO:0030003 180 0.013
dendrite development GO:0016358 72 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
macromolecule catabolic process GO:0009057 58 0.013
growth GO:0040007 165 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
macromolecule localization GO:0033036 252 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
protein transport GO:0015031 132 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
circulatory system development GO:0072359 134 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
lipid storage GO:0019915 1 0.012
glycerophospholipid metabolic process GO:0006650 47 0.012
cell adhesion GO:0007155 110 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
liver development GO:0001889 90 0.012
adult locomotory behavior GO:0008344 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
mesoderm development GO:0007498 2 0.012
male gamete generation GO:0048232 99 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
circadian rhythm GO:0007623 88 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of hormone secretion GO:0046888 46 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
response to toxic substance GO:0009636 133 0.012
protein complex assembly GO:0006461 263 0.012
gamete generation GO:0007276 124 0.012
response to radiation GO:0009314 137 0.012
forebrain development GO:0030900 98 0.012
regulation of gtpase activity GO:0043087 57 0.012
b cell differentiation GO:0030183 2 0.012
divalent metal ion transport GO:0070838 132 0.012
regulation of dna metabolic process GO:0051052 60 0.011
purine containing compound catabolic process GO:0072523 138 0.011
proteolysis GO:0006508 175 0.011
olfactory behavior GO:0042048 2 0.011
response to external biotic stimulus GO:0043207 221 0.011
salivary gland development GO:0007431 3 0.011
regulation of metal ion transport GO:0010959 118 0.011
muscle system process GO:0003012 115 0.011
response to bacterium GO:0009617 200 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
nucleotide metabolic process GO:0009117 279 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of anatomical structure size GO:0090066 135 0.011
alcohol metabolic process GO:0006066 77 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
protein localization GO:0008104 191 0.011
aging GO:0007568 241 0.011
cation homeostasis GO:0055080 195 0.011
cellular response to lipid GO:0071396 201 0.011
molting cycle process GO:0022404 2 0.011
regulation of hydrolase activity GO:0051336 143 0.011
protein homooligomerization GO:0051260 91 0.011
purine containing compound metabolic process GO:0072521 253 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
regulation of blood vessel size GO:0050880 89 0.011
actin cytoskeleton organization GO:0030036 73 0.011
nephron tubule development GO:0072080 12 0.011
formation of primary germ layer GO:0001704 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
establishment of tissue polarity GO:0007164 2 0.011
response to biotic stimulus GO:0009607 226 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of protein localization GO:0032880 81 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.011
urogenital system development GO:0001655 78 0.010
salivary gland morphogenesis GO:0007435 1 0.010
membrane organization GO:0061024 94 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
cell cycle GO:0007049 101 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
long chain fatty acid metabolic process GO:0001676 32 0.010
amine transport GO:0015837 57 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
epithelial cell differentiation GO:0030855 71 0.010
regulation of secretion by cell GO:1903530 208 0.010
cofactor metabolic process GO:0051186 95 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of neuron projection development GO:0010977 46 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
response to glucocorticoid GO:0051384 223 0.010

Frmd4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.043
sensory system disease DOID:0050155 0 0.020
disease of metabolism DOID:0014667 0 0.017
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
inherited metabolic disorder DOID:655 0 0.013
urinary system disease DOID:18 0 0.010
cardiovascular system disease DOID:1287 0 0.010