Rattus norvegicus

22 known processes

Fth1

ferritin, heavy polypeptide 1

(Aliases: Fth)

Fth1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
multi organism reproductive process GO:0044703 262 0.257
positive regulation of response to stimulus GO:0048584 285 0.256
reproduction GO:0000003 245 0.255
response to oxygen levels GO:0070482 265 0.214
multicellular organismal reproductive process GO:0048609 233 0.187
regulation of rna biosynthetic process GO:2001141 381 0.181
regulation of cellular protein metabolic process GO:0032268 267 0.181
response to cadmium ion GO:0046686 35 0.159
enzyme linked receptor protein signaling pathway GO:0007167 116 0.146
nucleic acid templated transcription GO:0097659 379 0.137
single organism reproductive process GO:0044702 297 0.132
cellular response to endogenous stimulus GO:0071495 377 0.122
negative regulation of cell death GO:0060548 229 0.119
response to nutrient levels GO:0031667 370 0.115
cellular response to hormone stimulus GO:0032870 247 0.110
response to inorganic substance GO:0010035 377 0.107
Rat
response to peptide hormone GO:0043434 278 0.104
regulation of transcription dna templated GO:0006355 374 0.096
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.093
monovalent inorganic cation transport GO:0015672 172 0.093
protein phosphorylation GO:0006468 345 0.091
negative regulation of nucleic acid templated transcription GO:1903507 117 0.091
regeneration GO:0031099 163 0.088
regulation of protein phosphorylation GO:0001932 183 0.087
response to bacterium GO:0009617 200 0.086
sexual reproduction GO:0019953 148 0.082
regulation of rna metabolic process GO:0051252 391 0.081
chemical homeostasis GO:0048878 292 0.080
response to peptide GO:1901652 292 0.079
regulation of phosphorus metabolic process GO:0051174 349 0.077
catabolic process GO:0009056 351 0.077
response to glucocorticoid GO:0051384 223 0.077
regulation of protein metabolic process GO:0051246 289 0.075
spermatogenesis GO:0007283 99 0.073
regulation of catalytic activity GO:0050790 304 0.072
cellular amino acid metabolic process GO:0006520 107 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
carbohydrate derivative catabolic process GO:1901136 147 0.069
positive regulation of gene expression GO:0010628 244 0.068
gamete generation GO:0007276 124 0.067
regulation of molecular function GO:0065009 398 0.067
glycosyl compound metabolic process GO:1901657 182 0.067
single organism catabolic process GO:0044712 283 0.066
cellular component assembly GO:0022607 360 0.066
response to corticosteroid GO:0031960 235 0.066
regulation of immune system process GO:0002682 123 0.065
organic acid metabolic process GO:0006082 292 0.062
response to estrogen GO:0043627 232 0.061
response to nutrient GO:0007584 248 0.061
cellular catabolic process GO:0044248 295 0.059
cellular component movement GO:0006928 248 0.059
rna metabolic process GO:0016070 406 0.057
cellular response to reactive oxygen species GO:0034614 55 0.056
positive regulation of molecular function GO:0044093 230 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.055
negative regulation of apoptotic process GO:0043066 181 0.053
response to metal ion GO:0010038 253 0.053
Rat
immune system process GO:0002376 204 0.053
negative regulation of biosynthetic process GO:0009890 168 0.053
positive regulation of phosphate metabolic process GO:0045937 262 0.052
response to decreased oxygen levels GO:0036293 237 0.052
gland development GO:0048732 155 0.051
regulation of phosphate metabolic process GO:0019220 349 0.051
cellular response to oxygen containing compound GO:1901701 386 0.051
regulation of programmed cell death GO:0043067 341 0.051
negative regulation of gene expression GO:0010629 199 0.050
protein complex subunit organization GO:0071822 302 0.050
negative regulation of rna biosynthetic process GO:1902679 118 0.050
male gamete generation GO:0048232 99 0.049
cellular response to insulin stimulus GO:0032869 81 0.048
negative regulation of metabolic process GO:0009892 331 0.047
negative regulation of macromolecule metabolic process GO:0010605 260 0.047
cation transport GO:0006812 382 0.047
cellular component biogenesis GO:0044085 368 0.046
response to hypoxia GO:0001666 231 0.045
carboxylic acid metabolic process GO:0019752 289 0.044
regulation of immune response GO:0050776 55 0.044
negative regulation of response to stimulus GO:0048585 155 0.044
response to acid chemical GO:0001101 222 0.044
regulation of cell differentiation GO:0045595 320 0.043
ribosome biogenesis GO:0042254 8 0.043
macromolecular complex assembly GO:0065003 273 0.043
leukocyte mediated cytotoxicity GO:0001909 10 0.042
positive regulation of phosphorylation GO:0042327 177 0.042
protein transport GO:0015031 132 0.042
cellular response to oxidative stress GO:0034599 76 0.042
oxoacid metabolic process GO:0043436 290 0.042
developmental process involved in reproduction GO:0003006 159 0.042
response to oxidative stress GO:0006979 186 0.042
negative regulation of programmed cell death GO:0043069 183 0.041
response to reactive oxygen species GO:0000302 120 0.041
cellular macromolecular complex assembly GO:0034622 58 0.041
salivary gland development GO:0007431 3 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
response to hydrogen peroxide GO:0042542 89 0.040
regulation of phosphorylation GO:0042325 248 0.040
defense response GO:0006952 194 0.040
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
response to carbohydrate GO:0009743 183 0.039
macromolecule localization GO:0033036 252 0.039
organophosphate metabolic process GO:0019637 370 0.039
response to transition metal nanoparticle GO:1990267 122 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
regulation of protein modification process GO:0031399 194 0.038
regulation of transferase activity GO:0051338 123 0.038
response to extracellular stimulus GO:0009991 380 0.038
regulation of adaptive immune response GO:0002819 8 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
secretion by cell GO:0032940 248 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
ossification GO:0001503 70 0.037
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.037
organ regeneration GO:0031100 101 0.036
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.036
multicellular organism reproduction GO:0032504 233 0.036
regulation of signal transduction GO:0009966 318 0.036
placenta development GO:0001890 22 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.035
cellular ketone metabolic process GO:0042180 51 0.034
rna biosynthetic process GO:0032774 380 0.034
regulation of cell proliferation GO:0042127 359 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
response to monosaccharide GO:0034284 159 0.032
reproductive process GO:0022414 372 0.032
nucleotide metabolic process GO:0009117 279 0.032
cell projection organization GO:0030030 302 0.032
atp catabolic process GO:0006200 54 0.032
ribose phosphate biosynthetic process GO:0046390 87 0.032
organic substance catabolic process GO:1901575 316 0.031
homeostatic process GO:0042592 331 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
amine metabolic process GO:0009308 38 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
regulation of body fluid levels GO:0050878 90 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.029
response to retinoic acid GO:0032526 63 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
intracellular signal transduction GO:0035556 314 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
protein targeting GO:0006605 61 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
multicellular organismal homeostasis GO:0048871 49 0.028
apoptotic process GO:0006915 381 0.028
osteoblast differentiation GO:0001649 26 0.028
regulation of cellular component movement GO:0051270 150 0.028
positive regulation of transcription dna templated GO:0045893 197 0.027
regulation of secretion GO:0051046 224 0.027
t cell activation GO:0042110 29 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
intracellular transport GO:0046907 185 0.026
neuron development GO:0048666 286 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
neuron projection development GO:0031175 273 0.026
protein complex assembly GO:0006461 263 0.025
response to glucose GO:0009749 136 0.025
protein homooligomerization GO:0051260 91 0.025
response to estradiol GO:0032355 164 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
cation homeostasis GO:0055080 195 0.025
transcription dna templated GO:0006351 377 0.025
t cell differentiation GO:0030217 9 0.025
immune response GO:0006955 104 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
negative regulation of rna metabolic process GO:0051253 123 0.024
multicellular organismal catabolic process GO:0044243 2 0.024
aromatic compound catabolic process GO:0019439 168 0.023
regulation of cellular localization GO:0060341 263 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
response to hexose GO:0009746 144 0.022
purine nucleotide catabolic process GO:0006195 136 0.022
regulation of cellular component organization GO:0051128 368 0.022
regulation of hydrolase activity GO:0051336 143 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
protein complex biogenesis GO:0070271 263 0.022
establishment of protein localization GO:0045184 141 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
tissue development GO:0009888 252 0.021
programmed cell death GO:0012501 392 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
regulation of secretion by cell GO:1903530 208 0.021
regulation of cell killing GO:0031341 12 0.021
positive regulation of developmental process GO:0051094 283 0.020
regulation of system process GO:0044057 208 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
locomotion GO:0040011 237 0.020
insulin receptor signaling pathway GO:0008286 24 0.020
positive regulation of protein modification process GO:0031401 142 0.019
negative regulation of transport GO:0051051 136 0.019
reproductive structure development GO:0048608 128 0.019
response to insulin GO:0032868 133 0.019
vesicle mediated transport GO:0016192 181 0.019
macromolecule catabolic process GO:0009057 58 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
negative regulation of cell communication GO:0010648 158 0.019
organic cyclic compound catabolic process GO:1901361 175 0.018
brain development GO:0007420 247 0.018
regulation of apoptotic process GO:0042981 335 0.018
positive regulation of immune system process GO:0002684 90 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of immune effector process GO:0002697 32 0.018
regulation of telomerase activity GO:0051972 2 0.018
central nervous system development GO:0007417 311 0.018
response to other organism GO:0051707 220 0.018
gonad development GO:0008406 104 0.018
ion homeostasis GO:0050801 212 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of immune response GO:0050778 42 0.017
translation GO:0006412 35 0.017
neuron differentiation GO:0030182 368 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
cytoplasmic transport GO:0016482 115 0.017
female pregnancy GO:0007565 122 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
single organism cellular localization GO:1902580 102 0.016
regulation of blood vessel size GO:0050880 89 0.016
single organism biosynthetic process GO:0044711 342 0.016
cell motility GO:0048870 202 0.016
protein processing GO:0016485 68 0.016
intracellular protein transport GO:0006886 79 0.016
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
regulation of cellular response to insulin stimulus GO:1900076 16 0.015
protein oligomerization GO:0051259 191 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
protein localization GO:0008104 191 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
circulatory system process GO:0003013 183 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
development of primary sexual characteristics GO:0045137 107 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
membrane organization GO:0061024 94 0.014
nucleotide catabolic process GO:0009166 139 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cellular response to stress GO:0033554 269 0.014
regulation of protein kinase activity GO:0045859 105 0.014
negative regulation of signal transduction GO:0009968 83 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
sex differentiation GO:0007548 113 0.014
response to hyperoxia GO:0055093 45 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of metal ion transport GO:0010959 118 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
negative regulation of protein maturation GO:1903318 47 0.013
ion transmembrane transport GO:0034220 365 0.013
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.013
lymphocyte mediated immunity GO:0002449 14 0.013
cellular macromolecule localization GO:0070727 122 0.013
nucleoside metabolic process GO:0009116 179 0.013
epithelium development GO:0060429 96 0.012
cellular protein localization GO:0034613 122 0.012
cell redox homeostasis GO:0045454 1 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of tube size GO:0035150 89 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
response to vitamin GO:0033273 131 0.012
response to growth factor GO:0070848 189 0.012
response to toxic substance GO:0009636 133 0.012
purine containing compound catabolic process GO:0072523 138 0.012
inflammatory response GO:0006954 150 0.012
response to ketone GO:1901654 182 0.012
collagen catabolic process GO:0030574 2 0.012
ribonucleoside diphosphate biosynthetic process GO:0009188 10 0.012
positive regulation of cell development GO:0010720 176 0.012
angiogenesis GO:0001525 53 0.012
cellular response to external stimulus GO:0071496 118 0.012
collagen metabolic process GO:0032963 21 0.012
cellular amine metabolic process GO:0044106 38 0.012
positive regulation of signaling GO:0023056 270 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.011
male sex differentiation GO:0046661 64 0.011
metal ion transport GO:0030001 289 0.011
glycerolipid metabolic process GO:0046486 67 0.011
response to activity GO:0014823 73 0.011
negative regulation of molecular function GO:0044092 133 0.011
proteolysis GO:0006508 175 0.011
regulation of cell development GO:0060284 263 0.011
protein refolding GO:0042026 3 0.011
regulation of neurogenesis GO:0050767 247 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
t cell mediated cytotoxicity GO:0001913 5 0.011
positive regulation of immune effector process GO:0002699 19 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 7 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
regulation of nervous system development GO:0051960 264 0.010
negative regulation of signaling GO:0023057 157 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010

Fth1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.067
nervous system disease DOID:863 0 0.067
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014