Rattus norvegicus

0 known processes

Fus

fusion (involved in t(12;16) in malignant liposarcoma) (human)

Fus biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rna splicing GO:0033119 3 0.533
regulation of mrna splicing via spliceosome GO:0048024 3 0.267
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.169
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.156
alternative mrna splicing via spliceosome GO:0000380 4 0.146
rna metabolic process GO:0016070 406 0.141
regulation of rna metabolic process GO:0051252 391 0.137
anterior posterior pattern specification GO:0009952 1 0.118
multicellular organism reproduction GO:0032504 233 0.113
negative regulation of gene expression GO:0010629 199 0.102
organelle organization GO:0006996 266 0.096
rna stabilization GO:0043489 2 0.094
embryonic pattern specification GO:0009880 1 0.084
multi organism reproductive process GO:0044703 262 0.083
negative regulation of metabolic process GO:0009892 331 0.074
regulation of mrna stability GO:0043488 3 0.071
reproduction GO:0000003 245 0.069
single organism reproductive process GO:0044702 297 0.067
single organism organelle organization GO:1902589 180 0.065
positive regulation of gene expression GO:0010628 244 0.065
reproductive process GO:0022414 372 0.062
axis specification GO:0009798 4 0.061
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.060
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
sexual reproduction GO:0019953 148 0.060
regulation of rna splicing GO:0043484 6 0.059
negative regulation of macromolecule metabolic process GO:0010605 260 0.057
negative regulation of rna metabolic process GO:0051253 123 0.054
cellular component biogenesis GO:0044085 368 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.051
cytoskeleton organization GO:0007010 111 0.050
female sex differentiation GO:0046660 59 0.048
cellular component assembly GO:0022607 360 0.046
gamete generation GO:0007276 124 0.046
cellular macromolecule localization GO:0070727 122 0.043
regulation of neuron projection development GO:0010975 161 0.042
multicellular organismal reproductive process GO:0048609 233 0.041
positive regulation of biosynthetic process GO:0009891 319 0.040
regulation of cell differentiation GO:0045595 320 0.039
cellular response to organic cyclic compound GO:0071407 202 0.039
rna splicing via transesterification reactions GO:0000375 7 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.036
regulation of multicellular organismal development GO:2000026 376 0.035
posttranscriptional regulation of gene expression GO:0010608 37 0.035
regulation of mrna processing GO:0050684 5 0.034
aging GO:0007568 241 0.034
development of primary female sexual characteristics GO:0046545 56 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.033
response to nutrient levels GO:0031667 370 0.032
developmental process involved in reproduction GO:0003006 159 0.031
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
response to extracellular stimulus GO:0009991 380 0.030
female gonad development GO:0008585 53 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
cell projection organization GO:0030030 302 0.029
neuron projection development GO:0031175 273 0.028
reproductive structure development GO:0048608 128 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
neuron development GO:0048666 286 0.027
single organism cellular localization GO:1902580 102 0.027
mrna processing GO:0006397 14 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
regulation of cell projection organization GO:0031344 175 0.026
rna splicing GO:0008380 11 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
gonad development GO:0008406 104 0.024
macromolecule localization GO:0033036 252 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 7 0.023
regulation of rna stability GO:0043487 3 0.022
embryonic axis specification GO:0000578 1 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
mrna stabilization GO:0048255 2 0.022
spermatogenesis GO:0007283 99 0.022
regulation of neuron differentiation GO:0045664 208 0.022
regulation of protein metabolic process GO:0051246 289 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
regulation of cell cycle GO:0051726 73 0.020
regulation of nervous system development GO:0051960 264 0.020
rna localization GO:0006403 4 0.020
regulation of molecular function GO:0065009 398 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
negative regulation of cell differentiation GO:0045596 99 0.018
regulation of neurogenesis GO:0050767 247 0.018
development of primary sexual characteristics GO:0045137 107 0.018
regulation of growth GO:0040008 105 0.018
regulation of cell development GO:0060284 263 0.018
regulation of apoptotic process GO:0042981 335 0.018
rhythmic process GO:0048511 156 0.018
embryo development GO:0009790 49 0.018
mrna splicing via spliceosome GO:0000398 7 0.018
cellular ketone metabolic process GO:0042180 51 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
positive regulation of cell development GO:0010720 176 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.016
regulation of cell proliferation GO:0042127 359 0.016
regulation of translation GO:0006417 27 0.016
chemical homeostasis GO:0048878 292 0.016
response to wounding GO:0009611 254 0.016
response to carbohydrate GO:0009743 183 0.016
developmental maturation GO:0021700 25 0.016
growth GO:0040007 165 0.015
metal ion transport GO:0030001 289 0.015
multicellular organism growth GO:0035264 1 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
cellular amine metabolic process GO:0044106 38 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
cellular component movement GO:0006928 248 0.015
nitrogen compound transport GO:0071705 229 0.015
regulation of cellular component organization GO:0051128 368 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of transcription dna templated GO:0006355 374 0.014
male gamete generation GO:0048232 99 0.014
mrna metabolic process GO:0016071 20 0.014
ion transmembrane transport GO:0034220 365 0.014
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
rna biosynthetic process GO:0032774 380 0.014
regeneration GO:0031099 163 0.014
cell cycle checkpoint GO:0000075 2 0.014
cation transport GO:0006812 382 0.014
nucleic acid templated transcription GO:0097659 379 0.014
regulation of cellular localization GO:0060341 263 0.014
reproductive system development GO:0061458 128 0.014
central nervous system development GO:0007417 311 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
homeostatic process GO:0042592 331 0.013
positive regulation of molecular function GO:0044093 230 0.013
regulation of programmed cell death GO:0043067 341 0.013
protein localization GO:0008104 191 0.013
amine metabolic process GO:0009308 38 0.013
cellular response to stress GO:0033554 269 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
positive regulation of developmental process GO:0051094 283 0.013
response to lipopolysaccharide GO:0032496 191 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
response to hexose GO:0009746 144 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
secretion GO:0046903 307 0.012
response to acid chemical GO:0001101 222 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
hormone transport GO:0009914 121 0.012
cellular response to lipid GO:0071396 201 0.011
brain development GO:0007420 247 0.011
sex differentiation GO:0007548 113 0.011
regulation of hormone levels GO:0010817 187 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
intracellular signal transduction GO:0035556 314 0.011
negative regulation of mrna splicing via spliceosome GO:0048025 2 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
neuron differentiation GO:0030182 368 0.011
response to monosaccharide GO:0034284 159 0.011
head development GO:0060322 247 0.011
programmed cell death GO:0012501 392 0.011
cellular response to acid chemical GO:0071229 75 0.011
cellular macromolecular complex assembly GO:0034622 58 0.010
germ cell development GO:0007281 25 0.010
rna processing GO:0006396 22 0.010
response to inorganic substance GO:0010035 377 0.010
response to ethanol GO:0045471 162 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
transcription dna templated GO:0006351 377 0.010
cellular chemical homeostasis GO:0055082 247 0.010
negative regulation of molecular function GO:0044092 133 0.010

Fus disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.040
disease of anatomical entity DOID:7 0 0.040
musculoskeletal system disease DOID:17 0 0.040
muscle tissue disease DOID:66 0 0.025
myopathy DOID:423 0 0.024