Rattus norvegicus

25 known processes

Fxyd1

FXYD domain-containing ion transport regulator 1

(Aliases: Plm)

Fxyd1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
apoptotic process GO:0006915 381 0.284
head development GO:0060322 247 0.275
negative regulation of multicellular organismal process GO:0051241 203 0.256
programmed cell death GO:0012501 392 0.251
regulation of programmed cell death GO:0043067 341 0.211
inflammatory response GO:0006954 150 0.188
cation transport GO:0006812 382 0.167
Rat
regulation of molecular function GO:0065009 398 0.162
negative regulation of metabolic process GO:0009892 331 0.138
immune system process GO:0002376 204 0.138
regulation of apoptotic process GO:0042981 335 0.136
response to transition metal nanoparticle GO:1990267 122 0.135
organic acid metabolic process GO:0006082 292 0.134
muscle structure development GO:0061061 87 0.128
transmembrane transport GO:0055085 412 0.127
Rat
response to wounding GO:0009611 254 0.121
response to metal ion GO:0010038 253 0.119
cellular response to stress GO:0033554 269 0.104
single organism biosynthetic process GO:0044711 342 0.101
divalent inorganic cation transport GO:0072511 134 0.101
positive regulation of signaling GO:0023056 270 0.100
response to inorganic substance GO:0010035 377 0.099
cellular lipid metabolic process GO:0044255 208 0.097
response to corticosteroid GO:0031960 235 0.096
monocarboxylic acid metabolic process GO:0032787 152 0.096
response to hypoxia GO:0001666 231 0.096
regulation of protein metabolic process GO:0051246 289 0.096
brain development GO:0007420 247 0.093
cellular amine metabolic process GO:0044106 38 0.092
metal ion transport GO:0030001 289 0.092
Rat
response to ethanol GO:0045471 162 0.090
response to nutrient levels GO:0031667 370 0.089
response to extracellular stimulus GO:0009991 380 0.089
response to oxidative stress GO:0006979 186 0.078
response to glucocorticoid GO:0051384 223 0.077
negative regulation of cellular metabolic process GO:0031324 281 0.076
ion transmembrane transport GO:0034220 365 0.075
Rat
response to lipopolysaccharide GO:0032496 191 0.074
regulation of cell differentiation GO:0045595 320 0.073
regulation of phosphate metabolic process GO:0019220 349 0.073
positive regulation of cell communication GO:0010647 271 0.072
muscle tissue development GO:0060537 58 0.068
response to other organism GO:0051707 220 0.066
cellular amino acid metabolic process GO:0006520 107 0.065
positive regulation of cell proliferation GO:0008284 249 0.065
response to oxygen levels GO:0070482 265 0.064
multi organism reproductive process GO:0044703 262 0.064
carboxylic acid metabolic process GO:0019752 289 0.063
reproductive process GO:0022414 372 0.061
oxoacid metabolic process GO:0043436 290 0.061
regulation of metal ion transport GO:0010959 118 0.060
divalent metal ion transport GO:0070838 132 0.060
response to decreased oxygen levels GO:0036293 237 0.059
anatomical structure morphogenesis GO:0009653 298 0.058
negative regulation of muscle organ development GO:0048635 8 0.057
response to peptide GO:1901652 292 0.057
response to estradiol GO:0032355 164 0.056
striated muscle tissue development GO:0014706 58 0.056
response to molecule of bacterial origin GO:0002237 194 0.055
positive regulation of multicellular organismal process GO:0051240 387 0.053
multi multicellular organism process GO:0044706 138 0.053
cellular response to endogenous stimulus GO:0071495 377 0.053
positive regulation of programmed cell death GO:0043068 157 0.052
regulation of multicellular organismal development GO:2000026 376 0.051
cellular component assembly GO:0022607 360 0.051
response to estrogen GO:0043627 232 0.051
regulation of cellular protein metabolic process GO:0032268 267 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.049
Rat
cellular response to oxygen containing compound GO:1901701 386 0.048
organophosphate metabolic process GO:0019637 370 0.046
Rat
glycogen metabolic process GO:0005977 23 0.046
catabolic process GO:0009056 351 0.045
Rat
cellular response to external stimulus GO:0071496 118 0.044
defense response GO:0006952 194 0.044
skeletal muscle cell differentiation GO:0035914 2 0.043
inorganic ion transmembrane transport GO:0098660 229 0.043
Rat
lipid metabolic process GO:0006629 283 0.042
calcium ion transport GO:0006816 131 0.042
negative regulation of cell death GO:0060548 229 0.042
positive regulation of apoptotic process GO:0043065 154 0.042
amine metabolic process GO:0009308 38 0.041
response to hexose GO:0009746 144 0.040
regulation of ion transport GO:0043269 245 0.040
Rat
regulation of calcium ion transport GO:0051924 77 0.039
regulation of synaptic transmission GO:0050804 141 0.039
macromolecular complex assembly GO:0065003 273 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.037
inorganic cation transmembrane transport GO:0098662 202 0.037
Rat
secretion GO:0046903 307 0.037
response to bacterium GO:0009617 200 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
developmental process involved in reproduction GO:0003006 159 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.036
Rat
cation homeostasis GO:0055080 195 0.036
response to monosaccharide GO:0034284 159 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
cation transmembrane transport GO:0098655 263 0.036
Rat
skeletal muscle tissue development GO:0007519 31 0.035
multicellular organism reproduction GO:0032504 233 0.035
positive regulation of developmental process GO:0051094 283 0.034
wound healing GO:0042060 122 0.034
behavior GO:0007610 205 0.034
protein complex assembly GO:0006461 263 0.034
chronic inflammatory response GO:0002544 16 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
small molecule biosynthetic process GO:0044283 124 0.034
cellular ketone metabolic process GO:0042180 51 0.033
negative regulation of rna biosynthetic process GO:1902679 118 0.033
regulation of phosphorylation GO:0042325 248 0.032
regulation of cellular component organization GO:0051128 368 0.032
Rat
cold acclimation GO:0009631 1 0.032
cellular carbohydrate metabolic process GO:0044262 72 0.032
regulation of muscle tissue development GO:1901861 25 0.032
organophosphate biosynthetic process GO:0090407 143 0.031
pyruvate metabolic process GO:0006090 27 0.031
carbohydrate metabolic process GO:0005975 130 0.031
cellular catabolic process GO:0044248 295 0.031
Rat
response to biotic stimulus GO:0009607 226 0.031
positive regulation of cell death GO:0010942 184 0.031
acute inflammatory response GO:0002526 58 0.031
cofactor metabolic process GO:0051186 95 0.030
tissue development GO:0009888 252 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
regulation of cell proliferation GO:0042127 359 0.028
Rat
regulation of signal transduction GO:0009966 318 0.028
response to nutrient GO:0007584 248 0.028
chemical homeostasis GO:0048878 292 0.028
regulation of hydrolase activity GO:0051336 143 0.028
response to external biotic stimulus GO:0043207 221 0.027
cellular response to abiotic stimulus GO:0071214 85 0.027
response to purine containing compound GO:0014074 126 0.027
cellular response to peptide GO:1901653 133 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
Rat
anion transport GO:0006820 178 0.027
female pregnancy GO:0007565 122 0.027
regulation of ion transmembrane transport GO:0034765 121 0.026
regulation of response to stress GO:0080134 126 0.026
long term synaptic potentiation GO:0060291 21 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
Rat
regulation of synaptic plasticity GO:0048167 70 0.026
positive regulation of molecular function GO:0044093 230 0.026
positive regulation of nervous system development GO:0051962 178 0.026
positive regulation of cell projection organization GO:0031346 111 0.025
positive regulation of ion transport GO:0043270 94 0.025
aging GO:0007568 241 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
single organism reproductive process GO:0044702 297 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
negative regulation of gene expression GO:0010629 199 0.024
reproduction GO:0000003 245 0.024
macromolecule localization GO:0033036 252 0.024
response to starvation GO:0042594 59 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.023
nucleotide metabolic process GO:0009117 279 0.023
Rat
negative regulation of developmental process GO:0051093 125 0.023
single organism catabolic process GO:0044712 283 0.023
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.023
purine containing compound metabolic process GO:0072521 253 0.022
Rat
response to insulin GO:0032868 133 0.022
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.022
regulation of secretion by cell GO:1903530 208 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
cellular response to extracellular stimulus GO:0031668 73 0.022
response to carbohydrate GO:0009743 183 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
homeostatic process GO:0042592 331 0.021
regulation of cation channel activity GO:2001257 23 0.021
rna biosynthetic process GO:0032774 380 0.021
regulation of calcium ion transmembrane transport GO:1903169 18 0.021
liver development GO:0001889 90 0.021
regulation of secretion GO:0051046 224 0.021
organic substance catabolic process GO:1901575 316 0.021
Rat
regulation of coenzyme metabolic process GO:0051196 1 0.020
gland development GO:0048732 155 0.020
central nervous system development GO:0007417 311 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
glucan metabolic process GO:0044042 23 0.020
regulation of rna metabolic process GO:0051252 391 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
Rat
metal ion homeostasis GO:0055065 186 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of response to wounding GO:1903034 69 0.019
hormone secretion GO:0046879 115 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
positive regulation of calcium ion transport GO:0051928 36 0.019
nitrogen compound transport GO:0071705 229 0.019
negative regulation of molecular function GO:0044092 133 0.019
response to radiation GO:0009314 137 0.019
calcium ion transmembrane transport GO:0070588 70 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
muscle organ development GO:0007517 50 0.018
chromosome segregation GO:0007059 2 0.018
alcohol metabolic process GO:0006066 77 0.018
cell projection organization GO:0030030 302 0.018
response to peptide hormone GO:0043434 278 0.018
monocarboxylic acid biosynthetic process GO:0072330 48 0.018
rna metabolic process GO:0016070 406 0.018
response to activity GO:0014823 73 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
neuron differentiation GO:0030182 368 0.018
circulatory system process GO:0003013 183 0.018
carbohydrate biosynthetic process GO:0016051 42 0.018
regulation of system process GO:0044057 208 0.018
secretion by cell GO:0032940 248 0.018
organic acid biosynthetic process GO:0016053 83 0.017
cellular glucan metabolic process GO:0006073 23 0.017
response to glucose GO:0009749 136 0.017
cellular polysaccharide metabolic process GO:0044264 23 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
Rat
ribose phosphate metabolic process GO:0019693 235 0.017
Rat
response to ketone GO:1901654 182 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
intracellular signal transduction GO:0035556 314 0.017
protein complex biogenesis GO:0070271 263 0.017
nucleoside metabolic process GO:0009116 179 0.017
Rat
regulation of neurogenesis GO:0050767 247 0.017
endocrine system development GO:0035270 30 0.017
lipid biosynthetic process GO:0008610 128 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of nervous system development GO:0051960 264 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of inflammatory response GO:0050727 48 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
transmission of nerve impulse GO:0019226 42 0.016
amide transport GO:0042886 105 0.016
regulation of cell projection organization GO:0031344 175 0.016
response to cytokine GO:0034097 215 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
response to osmotic stress GO:0006970 42 0.016
acetyl coa biosynthetic process GO:0006085 6 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
regeneration GO:0031099 163 0.015
reproductive system development GO:0061458 128 0.015
signal release GO:0023061 145 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
positive regulation of cell motility GO:2000147 97 0.015
response to organophosphorus GO:0046683 102 0.015
regulation of skeletal muscle cell differentiation GO:2001014 1 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
cellular response to iron ion starvation GO:0010106 1 0.015
cellular response to nutrient levels GO:0031669 60 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
cell cell signaling GO:0007267 335 0.015
negative regulation of skeletal muscle tissue development GO:0048642 3 0.015
brain renin angiotensin system GO:0002035 3 0.014
single organism behavior GO:0044708 130 0.014
multicellular organismal signaling GO:0035637 44 0.014
regulation of hormone secretion GO:0046883 106 0.014
cellular ion homeostasis GO:0006873 184 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
dna replication GO:0006260 37 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
heterocycle catabolic process GO:0046700 167 0.014
Rat
regulation of carbohydrate metabolic process GO:0006109 41 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
regulation of behavior GO:0050795 61 0.014
cellular homeostasis GO:0019725 252 0.014
glucose homeostasis GO:0042593 75 0.014
regulation of neuron differentiation GO:0045664 208 0.014
protein complex subunit organization GO:0071822 302 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
hormone transport GO:0009914 121 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
positive regulation of epithelial cell migration GO:0010634 13 0.013
regulation of response to external stimulus GO:0032101 106 0.013
phospholipid metabolic process GO:0006644 61 0.013
lateral ventricle development GO:0021670 1 0.013
synaptic transmission GO:0007268 235 0.013
dna metabolic process GO:0006259 96 0.013
sulfur compound metabolic process GO:0006790 70 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
Rat
cellular response to oxidative stress GO:0034599 76 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
cellular response to hypoxia GO:0071456 51 0.013
neurological system process GO:0050877 219 0.013
protein phosphorylation GO:0006468 345 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
muscle cell differentiation GO:0042692 52 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
Rat
regulation of catalytic activity GO:0050790 304 0.012
sexual reproduction GO:0019953 148 0.012
cellular response to alcohol GO:0097306 87 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
drinking behavior GO:0042756 11 0.012
regulation of transporter activity GO:0032409 50 0.012
regulation of transmembrane transport GO:0034762 122 0.012
polysaccharide metabolic process GO:0005976 25 0.012
regulation of insulin secretion GO:0050796 65 0.012
regulation of dna metabolic process GO:0051052 60 0.012
cellular component biogenesis GO:0044085 368 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
cellular cation homeostasis GO:0030003 180 0.012
renal system process GO:0003014 40 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
regulation of body fluid levels GO:0050878 90 0.012
regulation of muscle organ development GO:0048634 26 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
sex differentiation GO:0007548 113 0.012
tolerance induction dependent upon immune response GO:0002461 2 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
astrocyte differentiation GO:0048708 19 0.012
protein oligomerization GO:0051259 191 0.012
blood circulation GO:0008015 183 0.012
nucleic acid templated transcription GO:0097659 379 0.012
oxidation reduction process GO:0055114 304 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
heart process GO:0003015 57 0.012
negative regulation of transport GO:0051051 136 0.012
protein localization GO:0008104 191 0.012
regulation of defense response GO:0031347 68 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of peptide secretion GO:0002791 82 0.011
locomotion GO:0040011 237 0.011
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.011
carbohydrate homeostasis GO:0033500 75 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
lipid localization GO:0010876 62 0.011
organic hydroxy compound transport GO:0015850 77 0.011
hepaticobiliary system development GO:0061008 90 0.011
organelle organization GO:0006996 266 0.011
cytoskeleton organization GO:0007010 111 0.011
positive regulation of voltage gated calcium channel activity GO:1901387 1 0.011
multicellular organismal response to stress GO:0033555 25 0.011
neuron development GO:0048666 286 0.011
cellular chemical homeostasis GO:0055082 247 0.011
regulation of blood pressure GO:0008217 83 0.011
response to nitrosative stress GO:0051409 2 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
Rat
response to fungicide GO:0060992 20 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
rna localization GO:0006403 4 0.010
negative regulation of response to external stimulus GO:0032102 37 0.010
lipid transport GO:0006869 61 0.010
positive regulation of immune system process GO:0002684 90 0.010
regulation of cell growth GO:0001558 85 0.010
Rat
regulation of neuron death GO:1901214 115 0.010
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.010
epithelial cell proliferation GO:0050673 54 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
peptide transport GO:0015833 97 0.010
negative regulation of cell differentiation GO:0045596 99 0.010

Fxyd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.017
nervous system disease DOID:863 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011