Rattus norvegicus

14 known processes

Gab2

GRB2-associated binding protein 2

Gab2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.221
positive regulation of protein metabolic process GO:0051247 178 0.127
cellular metal ion homeostasis GO:0006875 172 0.103
intracellular signal transduction GO:0035556 314 0.103
regulation of phosphorus metabolic process GO:0051174 349 0.092
regulation of phosphate metabolic process GO:0019220 349 0.075
regulation of catalytic activity GO:0050790 304 0.073
positive regulation of response to stimulus GO:0048584 285 0.072
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.069
positive regulation of phosphate metabolic process GO:0045937 262 0.060
protein phosphorylation GO:0006468 345 0.059
positive regulation of molecular function GO:0044093 230 0.057
cellular response to endogenous stimulus GO:0071495 377 0.057
response to nutrient GO:0007584 248 0.057
positive regulation of catalytic activity GO:0043085 184 0.056
regulation of phosphorylation GO:0042325 248 0.052
single organism biosynthetic process GO:0044711 342 0.050
positive regulation of phosphorus metabolic process GO:0010562 262 0.049
regulation of apoptotic process GO:0042981 335 0.047
regulation of intracellular signal transduction GO:1902531 218 0.047
Fly
immune system process GO:0002376 204 0.046
Human Mouse Fly
regulation of protein kinase activity GO:0045859 105 0.045
regulation of protein metabolic process GO:0051246 289 0.045
protein complex assembly GO:0006461 263 0.042
organic acid metabolic process GO:0006082 292 0.042
regulation of protein phosphorylation GO:0001932 183 0.041
response to corticosteroid GO:0031960 235 0.040
positive regulation of transferase activity GO:0051347 81 0.039
tissue development GO:0009888 252 0.036
cellular ion homeostasis GO:0006873 184 0.035
response to glucocorticoid GO:0051384 223 0.034
positive regulation of cell communication GO:0010647 271 0.034
Human
cellular calcium ion homeostasis GO:0006874 160 0.033
positive regulation of mapk cascade GO:0043410 92 0.032
erk1 and erk2 cascade GO:0070371 48 0.031
cytoskeleton organization GO:0007010 111 0.031
regulation of kinase activity GO:0043549 117 0.031
secretion GO:0046903 307 0.029
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.029
response to cytokine GO:0034097 215 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
positive regulation of protein modification process GO:0031401 142 0.028
cellular response to alcohol GO:0097306 87 0.028
inflammatory response GO:0006954 150 0.028
nucleotide metabolic process GO:0009117 279 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
cation homeostasis GO:0055080 195 0.028
small molecule biosynthetic process GO:0044283 124 0.028
protein localization GO:0008104 191 0.028
regulation of transferase activity GO:0051338 123 0.026
myeloid leukocyte activation GO:0002274 36 0.026
Mouse
positive regulation of intracellular signal transduction GO:1902533 138 0.026
ribonucleotide metabolic process GO:0009259 231 0.025
response to peptide GO:1901652 292 0.025
cellular chemical homeostasis GO:0055082 247 0.024
regulation of transcription dna templated GO:0006355 374 0.024
positive regulation of phosphorylation GO:0042327 177 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
regulation of protein modification process GO:0031399 194 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
response to lipopolysaccharide GO:0032496 191 0.023
regulation of stem cell differentiation GO:2000736 2 0.023
ion transmembrane transport GO:0034220 365 0.022
regulation of immune system process GO:0002682 123 0.022
Mouse
regulation of signal transduction GO:0009966 318 0.022
Human Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cell adhesion GO:0007155 110 0.022
biological adhesion GO:0022610 110 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.021
reproductive process GO:0022414 372 0.021
cellular response to glucocorticoid stimulus GO:0071385 68 0.021
purine containing compound metabolic process GO:0072521 253 0.021
protein complex biogenesis GO:0070271 263 0.020
response to acid chemical GO:0001101 222 0.020
dephosphorylation GO:0016311 98 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
negative regulation of transport GO:0051051 136 0.019
metal ion homeostasis GO:0055065 186 0.019
rna metabolic process GO:0016070 406 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
response to nutrient levels GO:0031667 370 0.019
positive regulation of kinase activity GO:0033674 77 0.019
response to growth factor GO:0070848 189 0.019
ion homeostasis GO:0050801 212 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of mapk cascade GO:0043408 116 0.018
cell type specific apoptotic process GO:0097285 134 0.018
negative regulation of molecular function GO:0044092 133 0.018
cellular cation homeostasis GO:0030003 180 0.018
regulation of homeostatic process GO:0032844 101 0.018
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.018
brain development GO:0007420 247 0.018
apoptotic process GO:0006915 381 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
negative regulation of signaling GO:0023057 157 0.018
cellular amino acid metabolic process GO:0006520 107 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
regulation of programmed cell death GO:0043067 341 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
organophosphate catabolic process GO:0046434 148 0.017
cellular amine metabolic process GO:0044106 38 0.017
intracellular transport GO:0046907 185 0.017
Mouse
carboxylic acid metabolic process GO:0019752 289 0.017
single organism intracellular transport GO:1902582 166 0.016
Mouse
negative regulation of cell death GO:0060548 229 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
chemical homeostasis GO:0048878 292 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
amine metabolic process GO:0009308 38 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.015
adult locomotory behavior GO:0008344 4 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
kidney development GO:0001822 67 0.015
positive regulation of developmental process GO:0051094 283 0.015
cellular homeostasis GO:0019725 252 0.015
activation of protein kinase activity GO:0032147 47 0.015
blood circulation GO:0008015 183 0.015
axis specification GO:0009798 4 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
calcium ion homeostasis GO:0055074 162 0.015
regulation of catabolic process GO:0009894 113 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
Human
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
positive regulation of cell death GO:0010942 184 0.014
aging GO:0007568 241 0.014
response to radiation GO:0009314 137 0.014
renal system development GO:0072001 67 0.014
positive regulation of signaling GO:0023056 270 0.014
Human
lens development in camera type eye GO:0002088 13 0.014
mapk cascade GO:0000165 140 0.014
macromolecular complex subunit organization GO:0043933 339 0.013
single organism catabolic process GO:0044712 283 0.013
signal transduction involved in regulation of gene expression GO:0023019 4 0.013
muscle cell proliferation GO:0033002 84 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
heart morphogenesis GO:0003007 3 0.013
cation transport GO:0006812 382 0.013
response to ionizing radiation GO:0010212 59 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
Fly
liver development GO:0001889 90 0.013
response to decreased oxygen levels GO:0036293 237 0.013
cellular catabolic process GO:0044248 295 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
urogenital system development GO:0001655 78 0.013
positive regulation of gene expression GO:0010628 244 0.013
organelle organization GO:0006996 266 0.013
ras protein signal transduction GO:0007265 29 0.013
Fly
organic anion transport GO:0015711 132 0.013
rna biosynthetic process GO:0032774 380 0.013
wound healing GO:0042060 122 0.013
cytoplasmic transport GO:0016482 115 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
cellular component biogenesis GO:0044085 368 0.012
positive regulation of immune system process GO:0002684 90 0.012
Mouse
negative regulation of phosphate metabolic process GO:0045936 80 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of hydrolase activity GO:0051336 143 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
nucleic acid templated transcription GO:0097659 379 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.012
establishment of protein localization GO:0045184 141 0.012
response to estradiol GO:0032355 164 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
head development GO:0060322 247 0.011
actin cytoskeleton organization GO:0030036 73 0.011
response to inorganic substance GO:0010035 377 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein transport GO:0015031 132 0.011
sympathetic nervous system development GO:0048485 1 0.011
behavioral response to ethanol GO:0048149 1 0.011
eye morphogenesis GO:0048592 4 0.011
protein oligomerization GO:0051259 191 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cellular protein localization GO:0034613 122 0.011
organophosphate metabolic process GO:0019637 370 0.011
immune effector process GO:0002252 53 0.011
Mouse
glutamate receptor signaling pathway GO:0007215 43 0.011
second messenger mediated signaling GO:0019932 51 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
oxoacid metabolic process GO:0043436 290 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
positive regulation of serotonin secretion GO:0014064 1 0.011
positive regulation of signal transduction GO:0009967 175 0.011
Human
response to starvation GO:0042594 59 0.011
developmental process involved in reproduction GO:0003006 159 0.011
secretion by cell GO:0032940 248 0.011
Mouse
b cell differentiation GO:0030183 2 0.011
dna integrity checkpoint GO:0031570 2 0.011
regulation of rna metabolic process GO:0051252 391 0.011
carboxylic acid transport GO:0046942 115 0.011
positive regulation of locomotion GO:0040017 102 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
Human
detection of visible light GO:0009584 3 0.010
alcohol metabolic process GO:0006066 77 0.010
bmp signaling pathway GO:0030509 4 0.010
purine nucleoside metabolic process GO:0042278 169 0.010

Gab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011