|
|
transmembrane transport
|
GO:0055085 |
412 |
0.723
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.593
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.587
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.526
|
Fly |
|
|
synapse assembly
|
GO:0007416 |
29 |
0.511
|
Fly |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.507
|
Fly |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.476
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
42 |
0.463
|
Zebrafish |
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.460
|
Zebrafish Fly |
|
|
brain development
|
GO:0007420 |
247 |
0.454
|
|
|
|
head development
|
GO:0060322 |
247 |
0.445
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.439
|
|
|
|
cellular response to histamine
|
GO:0071420 |
3 |
0.417
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.371
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.344
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.317
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.316
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.303
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.303
|
Fly |
|
|
defecation
|
GO:0030421 |
1 |
0.293
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.288
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.285
|
Fly |
|
|
learning or memory
|
GO:0007611 |
90 |
0.284
|
Fly |
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.276
|
|
|
|
synaptic transmission glycinergic
|
GO:0060012 |
2 |
0.268
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
26 |
0.266
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.261
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.259
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.234
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.232
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.222
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.221
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.217
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.212
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.211
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.210
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.210
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.205
|
Zebrafish Rat Fly |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.203
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.203
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.202
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.193
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.191
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.189
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.189
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
42 |
0.182
|
|
|
|
feeding behavior
|
GO:0007631 |
53 |
0.179
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.178
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.178
|
|
|
|
response to histamine
|
GO:0034776 |
3 |
0.175
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.175
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.174
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.166
|
|
|
|
exploration behavior
|
GO:0035640 |
1 |
0.166
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.165
|
|
|
|
response to cocaine
|
GO:0042220 |
39 |
0.165
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.163
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.162
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.160
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.160
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.159
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.155
|
|
|
|
exocytosis
|
GO:0006887 |
60 |
0.154
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.151
|
|
|
|
acid secretion
|
GO:0046717 |
48 |
0.149
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.149
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.147
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.147
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.147
|
Zebrafish Rat Fly |
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.146
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.146
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.145
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.143
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.142
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.142
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
77 |
0.141
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.140
|
Zebrafish Fly |
|
|
neurological system process
|
GO:0050877 |
219 |
0.137
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.136
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.136
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.135
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.135
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.133
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.132
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
21 |
0.131
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.130
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.130
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.127
|
|
|
|
positive regulation of saliva secretion
|
GO:0046878 |
3 |
0.126
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.125
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.124
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.123
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.123
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.122
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.122
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.121
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.121
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.118
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.118
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.116
|
|
|
|
glutamate secretion
|
GO:0014047 |
19 |
0.115
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.114
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
29 |
0.114
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.114
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.114
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.113
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.112
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.111
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.110
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.110
|
|
|
|
locomotory exploration behavior
|
GO:0035641 |
1 |
0.109
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.109
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.109
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.107
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
37 |
0.107
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.106
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.106
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
33 |
0.103
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
83 |
0.103
|
Zebrafish Rat Fly |
|
|
positive regulation of hormone secretion
|
GO:0046887 |
65 |
0.102
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.102
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.101
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.100
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
25 |
0.100
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.099
|
|
|
|
peptide secretion
|
GO:0002790 |
86 |
0.099
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.099
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.098
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.098
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.095
|
|
|
|
amino acid transport
|
GO:0006865 |
70 |
0.095
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.095
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.095
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.094
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.093
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.092
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.091
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.091
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
3 |
0.090
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.089
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.089
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.089
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.088
|
|
|
|
urinary bladder smooth muscle contraction
|
GO:0014832 |
4 |
0.088
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.087
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.087
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.087
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.086
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.086
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.086
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.085
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.084
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.084
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.083
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.083
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.082
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.082
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.081
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
3 |
0.080
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.080
|
|
|
|
dicarboxylic acid transport
|
GO:0006835 |
34 |
0.079
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.079
|
|
|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
8 |
0.077
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
17 |
0.077
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.077
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.077
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.077
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.076
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.076
|
|
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.075
|
|
|
|
telencephalon development
|
GO:0021537 |
62 |
0.075
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.075
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.075
|
|
|
|
positive regulation of synaptic vesicle exocytosis
|
GO:2000302 |
3 |
0.075
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.075
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.074
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.074
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.074
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.074
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.074
|
|
|
|
saliva secretion
|
GO:0046541 |
3 |
0.073
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.073
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.072
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.070
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.070
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.068
|
Fly |
|
|
anion transport
|
GO:0006820 |
178 |
0.068
|
|
|
|
sensory perception
|
GO:0007600 |
101 |
0.067
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.066
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
2 |
0.066
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.064
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.063
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
21 |
0.063
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.063
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.062
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.062
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.062
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.062
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.061
|
|
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.061
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.060
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.060
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
6 |
0.060
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.060
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.059
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.059
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.059
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.059
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.059
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.059
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
4 |
0.058
|
|
|
|
choline transport
|
GO:0015871 |
4 |
0.057
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.057
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
14 |
0.057
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.057
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.056
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.056
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.055
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.054
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.054
|
|
|
|
rhythmic synaptic transmission
|
GO:0060024 |
1 |
0.054
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.054
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.053
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
71 |
0.053
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.053
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.053
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.052
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.052
|
|
|
|
regulation of amino acid transport
|
GO:0051955 |
25 |
0.052
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.051
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.051
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.051
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.051
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
5 |
0.051
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.051
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.051
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.050
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.050
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.050
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.050
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.049
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.049
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
82 |
0.048
|
|
|
|
l glutamate import
|
GO:0051938 |
2 |
0.048
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
87 |
0.048
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.047
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
18 |
0.047
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.047
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.047
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.047
|
|
|
|
vesicle localization
|
GO:0051648 |
33 |
0.047
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.047
|
|
|
|
learning
|
GO:0007612 |
33 |
0.047
|
Fly |
|
|
regulation of gamma aminobutyric acid secretion
|
GO:0014052 |
6 |
0.047
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
21 |
0.046
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
47 |
0.046
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.046
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.046
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.046
|
|
|
|
peptide transport
|
GO:0015833 |
97 |
0.046
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.046
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.046
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
34 |
0.045
|
|
|
|
protein homooligomerization
|
GO:0051260 |
91 |
0.045
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.045
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.045
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.044
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.044
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
21 |
0.044
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
48 |
0.044
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.043
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.043
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
15 |
0.043
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
33 |
0.043
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.043
|
|
|
|
growth
|
GO:0040007 |
165 |
0.043
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.042
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.042
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.042
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.042
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.042
|
|
|
|
positive regulation of synaptic vesicle transport
|
GO:1902805 |
3 |
0.042
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.042
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.042
|
|
|
|
positive regulation of the force of heart contraction by norepinephrine
|
GO:0003061 |
1 |
0.041
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.041
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.041
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.041
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.041
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.041
|
|
|
|
hormone secretion
|
GO:0046879 |
115 |
0.041
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.041
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
56 |
0.041
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.040
|
|
|
|
insulin secretion
|
GO:0030073 |
69 |
0.040
|
|
|
|
pallium development
|
GO:0021543 |
42 |
0.040
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
8 |
0.040
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.040
|
|
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
1 |
0.040
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.040
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.040
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.039
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
80 |
0.039
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
42 |
0.039
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.039
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.038
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.038
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
19 |
0.038
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.038
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.038
|
|
|
|
positive regulation of renin secretion into blood stream
|
GO:1900135 |
1 |
0.038
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.038
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.038
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.038
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.038
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.038
|
|
|
|
glucose homeostasis
|
GO:0042593 |
75 |
0.037
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.037
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
84 |
0.037
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.037
|
|
|
|
hormone metabolic process
|
GO:0042445 |
69 |
0.037
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.037
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
28 |
0.037
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.036
|
|
|
|
diaphragm contraction
|
GO:0002086 |
2 |
0.036
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.036
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.035
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.035
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.035
|
|
|
|
sensory perception of temperature stimulus
|
GO:0050951 |
5 |
0.035
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
51 |
0.034
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.034
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.034
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.034
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.034
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.034
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.034
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.034
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
35 |
0.034
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.033
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
72 |
0.033
|
|
|
|
dicarboxylic acid catabolic process
|
GO:0043649 |
1 |
0.033
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
27 |
0.033
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.033
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.033
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
19 |
0.033
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.033
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.032
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.032
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.032
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.032
|
|
|
|
negative regulation of smooth muscle contraction
|
GO:0045986 |
7 |
0.032
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.032
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.032
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.032
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.032
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.031
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.031
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.031
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.031
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.031
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.031
|
|
|
|
amide transport
|
GO:0042886 |
105 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.031
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.030
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.030
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
18 |
0.030
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.030
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.030
|
|
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
5 |
0.030
|
|
|
|
ossification
|
GO:0001503 |
70 |
0.030
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.030
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.030
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
52 |
0.030
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.030
|
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
15 |
0.030
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.030
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
23 |
0.029
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.029
|
|
|
|
positive regulation of neurotransmitter secretion
|
GO:0001956 |
9 |
0.029
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
25 |
0.029
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.029
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
4 |
0.029
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
59 |
0.029
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.029
|
|
|
|
limbic system development
|
GO:0021761 |
38 |
0.029
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.029
|
Zebrafish Rat Fly |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.029
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.029
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
72 |
0.029
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.029
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
65 |
0.029
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.029
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.029
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.028
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.028
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.028
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.028
|
Fly |
|
|
negative regulation of synaptic transmission gabaergic
|
GO:0032229 |
6 |
0.028
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.028
|
|
|
|
positive regulation of growth
|
GO:0045927 |
55 |
0.028
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
1 |
0.028
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.028
|
Fly |
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
2 |
0.028
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.028
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.027
|
|
|
|
temperature homeostasis
|
GO:0001659 |
17 |
0.027
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.027
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
55 |
0.027
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.027
|
|
|
|
eye morphogenesis
|
GO:0048592 |
4 |
0.027
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.027
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.027
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.027
|
|
|
|
adult behavior
|
GO:0030534 |
16 |
0.027
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.027
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.026
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.026
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.026
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.026
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
84 |
0.026
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.026
|
|
|
|
negative regulation of uterine smooth muscle contraction
|
GO:0070473 |
2 |
0.026
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.026
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.026
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
31 |
0.026
|
|
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.025
|
|
|
|
response to axon injury
|
GO:0048678 |
59 |
0.025
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.025
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.025
|
|
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.025
|
|
|
|
camera type eye development
|
GO:0043010 |
48 |
0.025
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.025
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.025
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.025
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.025
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.025
|
|
|
|
associative learning
|
GO:0008306 |
19 |
0.025
|
Fly |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.025
|
|
|
|
protein tetramerization
|
GO:0051262 |
38 |
0.025
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.025
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.025
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
46 |
0.025
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.025
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.024
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
12 |
0.024
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.024
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.024
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.024
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.024
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.024
|
|
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
10 |
0.024
|
|
|
|
urinary tract smooth muscle contraction
|
GO:0014848 |
4 |
0.024
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.024
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.024
|
|
|
|
male sex differentiation
|
GO:0046661 |
64 |
0.024
|
|
|
|
receptor clustering
|
GO:0043113 |
13 |
0.024
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
65 |
0.024
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.024
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.023
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.023
|
|
|
|
positive regulation of serotonin secretion
|
GO:0014064 |
1 |
0.023
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.023
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
83 |
0.023
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.023
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.023
|
|
|
|
positive regulation of the force of heart contraction by epinephrine
|
GO:0003059 |
1 |
0.023
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
65 |
0.023
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
19 |
0.023
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.023
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.023
|
|
|
|
memory
|
GO:0007613 |
54 |
0.023
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.023
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
50 |
0.023
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.023
|
|
|
|
eating behavior
|
GO:0042755 |
21 |
0.022
|
|
|
|
negative regulation of amine transport
|
GO:0051953 |
24 |
0.022
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
4 |
0.022
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.022
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
11 |
0.022
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.022
|
|
|
|
detection of temperature stimulus
|
GO:0016048 |
4 |
0.022
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.022
|
|
|
|
renin secretion into blood stream
|
GO:0002001 |
1 |
0.022
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.022
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.022
|
|
|
|
membrane depolarization during cardiac muscle cell action potential
|
GO:0086012 |
1 |
0.022
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.022
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.022
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.022
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.022
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.022
|
|
