Rattus norvegicus

38 known processes

Gdf11

growth differentiation factor 11

(Aliases: BMP-11)

Gdf11 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.495
Rat
neuron development GO:0048666 286 0.459
nucleic acid templated transcription GO:0097659 379 0.369
Rat
neuron projection morphogenesis GO:0048812 122 0.365
anatomical structure morphogenesis GO:0009653 298 0.347
Mouse Rat
transcription dna templated GO:0006351 377 0.333
Rat
cell morphogenesis GO:0000902 142 0.313
Rat
regulation of transcription dna templated GO:0006355 374 0.296
Rat
cell projection organization GO:0030030 302 0.294
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.281
cell migration GO:0016477 197 0.255
Rat
carboxylic acid metabolic process GO:0019752 289 0.241
positive regulation of multicellular organismal process GO:0051240 387 0.225
Rat
negative regulation of cell death GO:0060548 229 0.224
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.216
axon development GO:0061564 96 0.209
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.209
brain development GO:0007420 247 0.204
Rat Fly
rna biosynthetic process GO:0032774 380 0.199
Rat
cellular component movement GO:0006928 248 0.197
Rat
cell projection morphogenesis GO:0048858 123 0.182
mesoderm development GO:0007498 2 0.181
positive regulation of developmental process GO:0051094 283 0.180
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.178
dendrite morphogenesis GO:0048813 43 0.176
positive regulation of biosynthetic process GO:0009891 319 0.175
regulation of rna biosynthetic process GO:2001141 381 0.175
Rat
cellular component morphogenesis GO:0032989 155 0.173
Rat
single organism reproductive process GO:0044702 297 0.172
Rat
rna metabolic process GO:0016070 406 0.170
Rat
embryonic skeletal system development GO:0048706 3 0.167
Rat
cardiovascular system development GO:0072358 134 0.163
regulation of rna metabolic process GO:0051252 391 0.161
Rat
neuron differentiation GO:0030182 368 0.161
purine nucleotide metabolic process GO:0006163 229 0.158
regulation of neuron projection development GO:0010975 161 0.158
oxoacid metabolic process GO:0043436 290 0.156
central nervous system development GO:0007417 311 0.155
Mouse Rat Fly
positive regulation of cell differentiation GO:0045597 217 0.154
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.152
Rat
negative regulation of nervous system development GO:0051961 79 0.150
cell part morphogenesis GO:0032990 123 0.149
embryonic skeletal system morphogenesis GO:0048704 3 0.149
Rat
motor neuron axon guidance GO:0008045 1 0.145
neuron projection development GO:0031175 273 0.142
apoptotic process GO:0006915 381 0.141
Rat
cellular amino acid metabolic process GO:0006520 107 0.137
dendrite development GO:0016358 72 0.134
positive regulation of cellular biosynthetic process GO:0031328 295 0.132
regulation of neurogenesis GO:0050767 247 0.127
regulation of apoptotic process GO:0042981 335 0.126
Rat
regulation of cellular component organization GO:0051128 368 0.125
Rat
axonogenesis GO:0007409 71 0.125
positive regulation of transcription dna templated GO:0045893 197 0.124
cellular response to organonitrogen compound GO:0071417 197 0.122
g protein coupled receptor signaling pathway GO:0007186 242 0.122
cell cell signaling GO:0007267 335 0.122
response to nutrient levels GO:0031667 370 0.121
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.119
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.118
chemical homeostasis GO:0048878 292 0.118
Rat
regulation of multicellular organismal development GO:2000026 376 0.117
gland development GO:0048732 155 0.117
Rat
amine metabolic process GO:0009308 38 0.117
negative regulation of cellular metabolic process GO:0031324 281 0.114
positive regulation of signaling GO:0023056 270 0.113
chemotaxis GO:0006935 66 0.113
cellular response to endogenous stimulus GO:0071495 377 0.112
Rat
regulation of cell differentiation GO:0045595 320 0.112
cellular response to nitrogen compound GO:1901699 210 0.111
transcription from rna polymerase ii promoter GO:0006366 252 0.111
regulation of cellular amino acid metabolic process GO:0006521 2 0.109
cell motility GO:0048870 202 0.107
Rat
response to corticosteroid GO:0031960 235 0.105
Rat
regulation of neuron differentiation GO:0045664 208 0.104
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.104
cellular component biogenesis GO:0044085 368 0.104
negative regulation of multicellular organismal process GO:0051241 203 0.103
positive regulation of neurogenesis GO:0050769 165 0.101
regulation of cell development GO:0060284 263 0.100
macromolecule localization GO:0033036 252 0.100
Rat
behavior GO:0007610 205 0.100
regulation of cell projection organization GO:0031344 175 0.097
negative regulation of metabolic process GO:0009892 331 0.097
positive regulation of neuron projection development GO:0010976 99 0.094
organ morphogenesis GO:0009887 75 0.093
Mouse Rat
organic acid metabolic process GO:0006082 292 0.093
homeostatic process GO:0042592 331 0.091
Rat
reproductive process GO:0022414 372 0.091
Rat
cellular component assembly GO:0022607 360 0.090
positive regulation of transport GO:0051050 245 0.090
negative regulation of developmental process GO:0051093 125 0.089
positive regulation of gene expression GO:0010628 244 0.089
regulation of intracellular signal transduction GO:1902531 218 0.089
positive regulation of nervous system development GO:0051962 178 0.088
regulation of cellular ketone metabolic process GO:0010565 27 0.087
locomotion GO:0040011 237 0.087
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.087
growth GO:0040007 165 0.087
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.086
regulation of signal transduction GO:0009966 318 0.086
cell growth GO:0016049 104 0.086
circulatory system development GO:0072359 134 0.084
regulation of nucleotide metabolic process GO:0006140 117 0.084
cellular response to hormone stimulus GO:0032870 247 0.084
Rat
negative regulation of apoptotic process GO:0043066 181 0.084
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.082
carbohydrate derivative metabolic process GO:1901135 346 0.082
positive regulation of nucleic acid templated transcription GO:1903508 197 0.082
regulation of protein metabolic process GO:0051246 289 0.081
single organism biosynthetic process GO:0044711 342 0.081
multicellular organismal reproductive process GO:0048609 233 0.080
Rat
regulation of phosphate metabolic process GO:0019220 349 0.080
regulation of nervous system development GO:0051960 264 0.080
head development GO:0060322 247 0.079
Rat Fly
response to extracellular stimulus GO:0009991 380 0.079
Rat
heart morphogenesis GO:0003007 3 0.078
positive regulation of cell development GO:0010720 176 0.078
programmed cell death GO:0012501 392 0.078
Rat
nucleotide metabolic process GO:0009117 279 0.078
negative regulation of gene expression GO:0010629 199 0.078
cellular amine metabolic process GO:0044106 38 0.077
tissue development GO:0009888 252 0.077
Mouse Rat
positive regulation of cell proliferation GO:0008284 249 0.076
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.076
macromolecular complex subunit organization GO:0043933 339 0.075
regulation of protein phosphorylation GO:0001932 183 0.075
cellular response to growth factor stimulus GO:0071363 162 0.074
negative regulation of neurogenesis GO:0050768 78 0.073
ribonucleotide metabolic process GO:0009259 231 0.073
organonitrogen compound biosynthetic process GO:1901566 167 0.073
reproduction GO:0000003 245 0.072
Rat
positive regulation of rna metabolic process GO:0051254 203 0.071
regulation of cell proliferation GO:0042127 359 0.071
Mouse Rat
response to ketone GO:1901654 182 0.071
Rat
positive regulation of response to stimulus GO:0048584 285 0.070
peptidyl tyrosine phosphorylation GO:0018108 72 0.070
epithelium development GO:0060429 96 0.069
Mouse Rat
positive regulation of signal transduction GO:0009967 175 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.067
secretion by cell GO:0032940 248 0.067
neuron projection guidance GO:0097485 24 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.065
cellular response to organic cyclic compound GO:0071407 202 0.065
Rat
anterior posterior pattern specification GO:0009952 1 0.064
Zebrafish Mouse
regulation of anatomical structure size GO:0090066 135 0.063
positive regulation of cell projection organization GO:0031346 111 0.062
cyclic nucleotide metabolic process GO:0009187 80 0.062
regulation of cellular localization GO:0060341 263 0.062
Rat
organelle organization GO:0006996 266 0.062
Rat
negative regulation of cell differentiation GO:0045596 99 0.062
intracellular signal transduction GO:0035556 314 0.062
regulation of cellular amine metabolic process GO:0033238 8 0.062
organophosphate metabolic process GO:0019637 370 0.062
gliogenesis GO:0042063 93 0.061
skeletal system development GO:0001501 41 0.061
Mouse Rat
forebrain neuron differentiation GO:0021879 7 0.061
cellular ketone metabolic process GO:0042180 51 0.061
protein phosphorylation GO:0006468 345 0.060
negative regulation of signaling GO:0023057 157 0.059
peptidyl amino acid modification GO:0018193 126 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.058
nucleoside phosphate biosynthetic process GO:1901293 102 0.057
positive regulation of nucleotide metabolic process GO:0045981 91 0.057
regulation of molecular function GO:0065009 398 0.057
Rat
negative regulation of programmed cell death GO:0043069 183 0.057
Rat
response to peptide hormone GO:0043434 278 0.056
response to estrogen GO:0043627 232 0.056
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.056
regulation of dendrite development GO:0050773 59 0.055
enzyme linked receptor protein signaling pathway GO:0007167 116 0.055
Rat
organophosphate biosynthetic process GO:0090407 143 0.055
purine containing compound metabolic process GO:0072521 253 0.054
cellular response to peptide hormone stimulus GO:0071375 120 0.053
purine ribonucleotide metabolic process GO:0009150 227 0.053
positive regulation of cellular amine metabolic process GO:0033240 3 0.053
regulation of cellular protein metabolic process GO:0032268 267 0.053
cellular response to stress GO:0033554 269 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.053
regulation of mesenchymal cell proliferation GO:0010464 4 0.053
negative regulation of transcription dna templated GO:0045892 116 0.052
cardiac ventricle development GO:0003231 1 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.052
developmental growth involved in morphogenesis GO:0060560 33 0.052
response to inorganic substance GO:0010035 377 0.052
forebrain development GO:0030900 98 0.052
muscle structure development GO:0061061 87 0.051
Rat
purine nucleoside metabolic process GO:0042278 169 0.051
synaptic transmission glutamatergic GO:0035249 33 0.051
response to alkaloid GO:0043279 132 0.050
multicellular organism reproduction GO:0032504 233 0.050
Rat
axon guidance GO:0007411 24 0.050
negative regulation of cell development GO:0010721 82 0.050
negative regulation of neuron differentiation GO:0045665 62 0.050
organ formation GO:0048645 3 0.048
catabolic process GO:0009056 351 0.048
regulation of cell morphogenesis GO:0022604 77 0.048
response to decreased oxygen levels GO:0036293 237 0.048
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.047
response to glucocorticoid GO:0051384 223 0.047
Rat
cation transport GO:0006812 382 0.047
Rat
salivary gland development GO:0007431 3 0.047
regulation of programmed cell death GO:0043067 341 0.047
Rat
protein transport GO:0015031 132 0.046
Rat
neuron fate commitment GO:0048663 4 0.046
glycosyl compound metabolic process GO:1901657 182 0.046
negative regulation of biosynthetic process GO:0009890 168 0.045
response to metal ion GO:0010038 253 0.045
mesoderm morphogenesis GO:0048332 1 0.045
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.045
negative regulation of osteoblast differentiation GO:0045668 2 0.045
positive regulation of neuron differentiation GO:0045666 126 0.045
nucleoside phosphate metabolic process GO:0006753 283 0.045
taxis GO:0042330 67 0.045
protein complex assembly GO:0006461 263 0.044
regulation of protein modification process GO:0031399 194 0.044
regulation of axonogenesis GO:0050770 37 0.044
peptidyl tyrosine modification GO:0018212 72 0.044
cytoskeleton organization GO:0007010 111 0.044
protein complex subunit organization GO:0071822 302 0.043
inflammatory response GO:0006954 150 0.043
cellular calcium ion homeostasis GO:0006874 160 0.043
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.043
Rat
cellular response to insulin stimulus GO:0032869 81 0.043
mesenchymal cell proliferation GO:0010463 4 0.042
developmental growth GO:0048589 100 0.042
Rat
carbohydrate metabolic process GO:0005975 130 0.042
purine containing compound catabolic process GO:0072523 138 0.041
development of primary sexual characteristics GO:0045137 107 0.041
macromolecular complex assembly GO:0065003 273 0.041
negative regulation of cell communication GO:0010648 158 0.041
response to purine containing compound GO:0014074 126 0.041
positive regulation of protein metabolic process GO:0051247 178 0.041
cardiac chamber development GO:0003205 1 0.040
cell fate determination GO:0001709 2 0.040
regulation of growth GO:0040008 105 0.040
Rat
gastrulation GO:0007369 2 0.040
camera type eye development GO:0043010 48 0.040
Mouse
purine nucleotide biosynthetic process GO:0006164 83 0.039
secretion GO:0046903 307 0.039
cellular response to cytokine stimulus GO:0071345 127 0.039
immune system process GO:0002376 204 0.039
Rat
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.039
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
Rat
nucleoside metabolic process GO:0009116 179 0.039
response to ethanol GO:0045471 162 0.039
Rat
mesonephros development GO:0001823 14 0.039
Mouse Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.039
positive regulation of protein modification process GO:0031401 142 0.039
purine ribonucleoside catabolic process GO:0046130 124 0.038
neurological system process GO:0050877 219 0.038
Rat
regulation of locomotion GO:0040012 148 0.038
Rat
response to nicotine GO:0035094 51 0.038
heart development GO:0007507 72 0.038
embryonic cranial skeleton morphogenesis GO:0048701 2 0.038
Rat
multicellular organism growth GO:0035264 1 0.038
ribose phosphate metabolic process GO:0019693 235 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
synaptic transmission GO:0007268 235 0.038
regulation of response to external stimulus GO:0032101 106 0.037
positive regulation of molecular function GO:0044093 230 0.037
Rat
sexual reproduction GO:0019953 148 0.037
negative regulation of cellular component organization GO:0051129 83 0.037
Rat
response to cytokine GO:0034097 215 0.037
Rat
forebrain generation of neurons GO:0021872 8 0.037
positive regulation of cellular protein metabolic process GO:0032270 167 0.037
calcium ion homeostasis GO:0055074 162 0.037
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.037
vesicle mediated transport GO:0016192 181 0.037
Rat
neuron projection extension GO:1990138 26 0.037
response to peptide GO:1901652 292 0.037
mapk cascade GO:0000165 140 0.037
reproductive structure development GO:0048608 128 0.036
regulation of calcium ion transport GO:0051924 77 0.036
Rat
developmental process involved in reproduction GO:0003006 159 0.036
cell type specific apoptotic process GO:0097285 134 0.036
regulation of secretion by cell GO:1903530 208 0.036
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
purine ribonucleotide catabolic process GO:0009154 136 0.035
aging GO:0007568 241 0.035
Rat
response to camp GO:0051591 91 0.035
response to hypoxia GO:0001666 231 0.035
Rat
cellular response to peptide GO:1901653 133 0.034
cellular chemical homeostasis GO:0055082 247 0.034
Rat
response to growth factor GO:0070848 189 0.034
ribonucleoside triphosphate metabolic process GO:0009199 141 0.034
ribonucleoside metabolic process GO:0009119 174 0.034
cellular nitrogen compound catabolic process GO:0044270 163 0.034
purine ribonucleoside metabolic process GO:0046128 168 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.034
transmembrane transport GO:0055085 412 0.033
cellular metal ion homeostasis GO:0006875 172 0.033
Rat
dorsal ventral axon guidance GO:0033563 1 0.033
neuron neuron synaptic transmission GO:0007270 60 0.033
response to insulin GO:0032868 133 0.033
positive regulation of protein phosphorylation GO:0001934 135 0.033
formation of primary germ layer GO:0001704 1 0.032
nucleoside phosphate catabolic process GO:1901292 140 0.032
localization of cell GO:0051674 202 0.032
Rat
response to carbohydrate GO:0009743 183 0.032
Rat
response to organophosphorus GO:0046683 102 0.032
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.031
single organism catabolic process GO:0044712 283 0.031
response to hexose GO:0009746 144 0.031
Rat
regulation of secretion GO:0051046 224 0.031
response to mechanical stimulus GO:0009612 134 0.031
nucleotide biosynthetic process GO:0009165 98 0.031
establishment of protein localization GO:0045184 141 0.031
Rat
jak stat cascade GO:0007259 26 0.031
ribonucleotide biosynthetic process GO:0009260 85 0.030
cellular homeostasis GO:0019725 252 0.030
Rat
positive regulation of ion transport GO:0043270 94 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.030
rhythmic process GO:0048511 156 0.030
Rat
camp metabolic process GO:0046058 63 0.030
gamete generation GO:0007276 124 0.030
purine nucleoside monophosphate metabolic process GO:0009126 84 0.030
intracellular transport GO:0046907 185 0.030
Rat
positive regulation of growth GO:0045927 55 0.030
response to nutrient GO:0007584 248 0.029
Rat
regulation of synaptic transmission glutamatergic GO:0051966 26 0.029
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.029
regulation of system process GO:0044057 208 0.029
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.029
forebrain neuron development GO:0021884 3 0.029
circadian rhythm GO:0007623 88 0.029
ribonucleoside catabolic process GO:0042454 126 0.028
monocarboxylic acid metabolic process GO:0032787 152 0.028
ribose phosphate biosynthetic process GO:0046390 87 0.028
single organism organelle organization GO:1902589 180 0.028
Rat
regulation of kinase activity GO:0043549 117 0.028
protein localization GO:0008104 191 0.027
Rat
negative regulation of neuron projection development GO:0010977 46 0.027
regulation of cellular component movement GO:0051270 150 0.027
Rat
protein complex biogenesis GO:0070271 263 0.027
biological adhesion GO:0022610 110 0.027
small gtpase mediated signal transduction GO:0007264 36 0.027
nucleotide catabolic process GO:0009166 139 0.027
regulation of catalytic activity GO:0050790 304 0.027
negative regulation of response to external stimulus GO:0032102 37 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
cyclic purine nucleotide metabolic process GO:0052652 62 0.027
multi organism reproductive process GO:0044703 262 0.027
Rat
regulation of protein kinase activity GO:0045859 105 0.027
cerebral cortex tangential migration GO:0021800 1 0.027
bmp signaling pathway GO:0030509 4 0.027
response to oxygen levels GO:0070482 265 0.026
Rat
organic substance catabolic process GO:1901575 316 0.026
metal ion transport GO:0030001 289 0.026
Rat
cognition GO:0050890 92 0.026
ion homeostasis GO:0050801 212 0.026
Rat
ribonucleotide catabolic process GO:0009261 136 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
dna metabolic process GO:0006259 96 0.026
nucleoside triphosphate metabolic process GO:0009141 144 0.026
regulation of neuron apoptotic process GO:0043523 83 0.026
response to radiation GO:0009314 137 0.026
Rat
ras protein signal transduction GO:0007265 29 0.026
regulation of hormone levels GO:0010817 187 0.025
neuron death GO:0070997 127 0.025
salivary gland morphogenesis GO:0007435 1 0.025
positive regulation of synaptic transmission GO:0050806 62 0.025
neural crest cell migration GO:0001755 1 0.025
regulation of cell growth GO:0001558 85 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
regulation of response to stress GO:0080134 126 0.025
neural crest cell development GO:0014032 2 0.025
regulation of neuron death GO:1901214 115 0.025
mesoderm formation GO:0001707 1 0.025
olfactory bulb interneuron differentiation GO:0021889 1 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
Rat
purine containing compound biosynthetic process GO:0072522 85 0.025
regulation of phosphorylation GO:0042325 248 0.024
positive regulation of cell communication GO:0010647 271 0.024
positive regulation of neurotransmitter secretion GO:0001956 9 0.024
liver development GO:0001889 90 0.024
gonad development GO:0008406 104 0.024
regulation of extent of cell growth GO:0061387 25 0.024
glial cell migration GO:0008347 11 0.024
regulation of hydrolase activity GO:0051336 143 0.024
regulation of cell migration GO:0030334 128 0.024
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
negative regulation of rna biosynthetic process GO:1902679 118 0.024
single organism intracellular transport GO:1902582 166 0.024
Rat
angiogenesis GO:0001525 53 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
nucleoside catabolic process GO:0009164 126 0.023
neurotransmitter gated ion channel clustering GO:0072578 3 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
Rat
actin filament based process GO:0030029 86 0.023
defense response GO:0006952 194 0.023
Rat
signal release GO:0023061 145 0.023
response to glucose GO:0009749 136 0.023
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
maintenance of location GO:0051235 17 0.022
negative regulation of cell projection organization GO:0031345 50 0.022
regulation of bmp signaling pathway GO:0030510 2 0.022
regulation of osteoblast differentiation GO:0045667 14 0.022
synapse organization GO:0050808 46 0.022
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.022
cytokine mediated signaling pathway GO:0019221 43 0.022
single organism behavior GO:0044708 130 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
epithelial cell migration GO:0010631 19 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
respiratory system process GO:0003016 3 0.022
sensory perception GO:0007600 101 0.021
protein heterooligomerization GO:0051291 89 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
Rat
cation homeostasis GO:0055080 195 0.021
Rat
respiratory gaseous exchange GO:0007585 4 0.021
metal ion homeostasis GO:0055065 186 0.021
Rat
alpha amino acid metabolic process GO:1901605 71 0.021
cell adhesion GO:0007155 110 0.021
reproductive system development GO:0061458 128 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
Rat
regulation of canonical wnt signaling pathway GO:0060828 4 0.020
neural crest cell differentiation GO:0014033 2 0.020
regulation of response to wounding GO:1903034 69 0.020
embryonic pattern specification GO:0009880 1 0.020
cyclic nucleotide biosynthetic process GO:0009190 63 0.020
neurotransmitter secretion GO:0007269 33 0.020
generation of precursor metabolites and energy GO:0006091 62 0.020
cellular catabolic process GO:0044248 295 0.020
nucleoside monophosphate metabolic process GO:0009123 93 0.020
organelle localization GO:0051640 55 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
regulation of nucleotide biosynthetic process GO:0030808 47 0.020
positive regulation of neuron migration GO:2001224 2 0.020
regulation of axon extension GO:0030516 24 0.020
axon extension GO:0048675 26 0.020
negative regulation of neuron death GO:1901215 69 0.020
organophosphate catabolic process GO:0046434 148 0.020
camp biosynthetic process GO:0006171 47 0.019
axon choice point recognition GO:0016198 2 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
response to monosaccharide GO:0034284 159 0.019
Rat
muscle organ development GO:0007517 50 0.019
Rat
positive regulation of secretion GO:0051047 140 0.019
positive regulation of locomotion GO:0040017 102 0.019
Rat
glial cell differentiation GO:0010001 65 0.019
regulation of muscle system process GO:0090257 79 0.019
Rat
learning or memory GO:0007611 90 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
multi multicellular organism process GO:0044706 138 0.019
Rat
negative regulation of protein metabolic process GO:0051248 114 0.019
positive regulation of cell growth GO:0030307 44 0.019
memory GO:0007613 54 0.019
cell projection assembly GO:0030031 21 0.019
regeneration GO:0031099 163 0.019
Rat
comma shaped body morphogenesis GO:0072049 2 0.019
ovulation cycle process GO:0022602 50 0.019
Rat
negative regulation of molecular function GO:0044092 133 0.019
cellular protein localization GO:0034613 122 0.019
Rat
regulation of neurotransmitter levels GO:0001505 42 0.019
catecholamine secretion GO:0050432 33 0.019
regulation of behavior GO:0050795 61 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
hepaticobiliary system development GO:0061008 90 0.018
peptide transport GO:0015833 97 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
calcium ion transport GO:0006816 131 0.018
Rat
negative regulation of transport GO:0051051 136 0.018
Rat
blood vessel morphogenesis GO:0048514 58 0.018
central nervous system neuron differentiation GO:0021953 17 0.018
negative regulation of response to wounding GO:1903035 23 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
regulation of mapk cascade GO:0043408 116 0.018
negative regulation of signal transduction GO:0009968 83 0.018
neurotransmitter transport GO:0006836 42 0.018
response to acid chemical GO:0001101 222 0.018
Rat
digestive system development GO:0055123 41 0.018
Rat
sex differentiation GO:0007548 113 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
body fluid secretion GO:0007589 41 0.018
protein targeting GO:0006605 61 0.018
Rat
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
morphogenesis of embryonic epithelium GO:0016331 3 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
cerebral cortex cell migration GO:0021795 4 0.018
atp metabolic process GO:0046034 72 0.017
cellular ion homeostasis GO:0006873 184 0.017
Rat
lipid metabolic process GO:0006629 283 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017

Gdf11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.020
gastrointestinal system disease DOID:77 0 0.018