Rattus norvegicus

109 known processes

Glul

glutamate-ammonia ligase (glutamine synthetase)

(Aliases: Glns)

Glul biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly GO:0022607 360 0.173
homeostatic process GO:0042592 331 0.157
cellular component biogenesis GO:0044085 368 0.155
cellular response to oxygen containing compound GO:1901701 386 0.140
regulation of secretion GO:0051046 224 0.120
response to biotic stimulus GO:0009607 226 0.119
cellular response to external stimulus GO:0071496 118 0.102
regulation of cellular component organization GO:0051128 368 0.098
cellular response to stress GO:0033554 269 0.092
positive regulation of multicellular organismal process GO:0051240 387 0.090
response to monosaccharide GO:0034284 159 0.088
response to other organism GO:0051707 220 0.085
cellular catabolic process GO:0044248 295 0.083
cellular response to endogenous stimulus GO:0071495 377 0.082
vesicle mediated transport GO:0016192 181 0.079
aging GO:0007568 241 0.079
programmed cell death GO:0012501 392 0.078
response to inorganic substance GO:0010035 377 0.078
apoptotic process GO:0006915 381 0.076
tissue development GO:0009888 252 0.072
reproductive process GO:0022414 372 0.071
regulation of apoptotic process GO:0042981 335 0.071
positive regulation of cell communication GO:0010647 271 0.070
response to nutrient levels GO:0031667 370 0.069
transmembrane transport GO:0055085 412 0.068
response to extracellular stimulus GO:0009991 380 0.066
head development GO:0060322 247 0.065
protein complex assembly GO:0006461 263 0.064
response to external biotic stimulus GO:0043207 221 0.063
response to bacterium GO:0009617 200 0.062
central nervous system development GO:0007417 311 0.061
regulation of programmed cell death GO:0043067 341 0.061
chemical homeostasis GO:0048878 292 0.061
response to glucocorticoid GO:0051384 223 0.060
response to molecule of bacterial origin GO:0002237 194 0.060
response to lipopolysaccharide GO:0032496 191 0.059
ion transmembrane transport GO:0034220 365 0.058
metal ion transport GO:0030001 289 0.057
response to carbohydrate GO:0009743 183 0.057
organelle organization GO:0006996 266 0.056
regulation of ion transport GO:0043269 245 0.055
protein complex subunit organization GO:0071822 302 0.055
carboxylic acid metabolic process GO:0019752 289 0.054
organic substance catabolic process GO:1901575 316 0.053
lipid metabolic process GO:0006629 283 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.053
protein oligomerization GO:0051259 191 0.053
cellular chemical homeostasis GO:0055082 247 0.053
secretion GO:0046903 307 0.051
cellular response to nitrogen compound GO:1901699 210 0.050
response to corticosteroid GO:0031960 235 0.049
macromolecular complex assembly GO:0065003 273 0.047
growth GO:0040007 165 0.047
intracellular signal transduction GO:0035556 314 0.047
cellular response to insulin stimulus GO:0032869 81 0.046
multi organism reproductive process GO:0044703 262 0.046
single organism catabolic process GO:0044712 283 0.046
organic acid metabolic process GO:0006082 292 0.046
cell cell signaling GO:0007267 335 0.045
ion homeostasis GO:0050801 212 0.044
cellular response to hormone stimulus GO:0032870 247 0.042
catabolic process GO:0009056 351 0.042
positive regulation of transport GO:0051050 245 0.042
cation transport GO:0006812 382 0.041
response to mechanical stimulus GO:0009612 134 0.041
response to cytokine GO:0034097 215 0.041
cellular response to organonitrogen compound GO:0071417 197 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
negative regulation of apoptotic process GO:0043066 181 0.039
response to metal ion GO:0010038 253 0.039
response to oxidative stress GO:0006979 186 0.039
blood circulation GO:0008015 183 0.039
positive regulation of cellular component organization GO:0051130 200 0.039
cation homeostasis GO:0055080 195 0.039
anion transport GO:0006820 178 0.038
response to peptide GO:1901652 292 0.038
response to hypoxia GO:0001666 231 0.038
regulation of intracellular signal transduction GO:1902531 218 0.038
regulation of cell proliferation GO:0042127 359 0.037
regulation of growth GO:0040008 105 0.037
protein complex biogenesis GO:0070271 263 0.037
positive regulation of secretion GO:0051047 140 0.036
negative regulation of metabolic process GO:0009892 331 0.036
cellular ion homeostasis GO:0006873 184 0.036
reproduction GO:0000003 245 0.035
cellular response to abiotic stimulus GO:0071214 85 0.035
cell type specific apoptotic process GO:0097285 134 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of molecular function GO:0065009 398 0.034
cytoskeleton organization GO:0007010 111 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
response to estrogen GO:0043627 232 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
intracellular transport GO:0046907 185 0.032
response to hexose GO:0009746 144 0.031
protein phosphorylation GO:0006468 345 0.031
nitrogen compound transport GO:0071705 229 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
neurological system process GO:0050877 219 0.030
response to starvation GO:0042594 59 0.030
regulation of cellular localization GO:0060341 263 0.030
hormone secretion GO:0046879 115 0.030
regulation of hormone levels GO:0010817 187 0.030
cellular response to extracellular stimulus GO:0031668 73 0.030
defense response GO:0006952 194 0.029
regulation of system process GO:0044057 208 0.029
response to glucose GO:0009749 136 0.029
purine containing compound metabolic process GO:0072521 253 0.029
protein homooligomerization GO:0051260 91 0.029
regulation of cell differentiation GO:0045595 320 0.029
response to acid chemical GO:0001101 222 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
endocytosis GO:0006897 84 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
multicellular organism reproduction GO:0032504 233 0.028
cellular cation homeostasis GO:0030003 180 0.028
regulation of nervous system development GO:0051960 264 0.027
response to insulin GO:0032868 133 0.027
proteolysis GO:0006508 175 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
regulation of signal transduction GO:0009966 318 0.027
cellular homeostasis GO:0019725 252 0.027
single organism reproductive process GO:0044702 297 0.027
single organism biosynthetic process GO:0044711 342 0.026
cellular macromolecule localization GO:0070727 122 0.026
protein transport GO:0015031 132 0.026
oxoacid metabolic process GO:0043436 290 0.026
signal release GO:0023061 145 0.026
cell growth GO:0016049 104 0.026
positive regulation of signaling GO:0023056 270 0.025
response to peptide hormone GO:0043434 278 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
neuron differentiation GO:0030182 368 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
sexual reproduction GO:0019953 148 0.025
cellular response to lipid GO:0071396 201 0.025
negative regulation of cell death GO:0060548 229 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
regulation of catalytic activity GO:0050790 304 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
rna biosynthetic process GO:0032774 380 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
regulation of proteasomal protein catabolic process GO:0061136 4 0.024
gamete generation GO:0007276 124 0.024
developmental process involved in reproduction GO:0003006 159 0.024
regulation of protein metabolic process GO:0051246 289 0.024
macromolecule localization GO:0033036 252 0.023
cellular response to nutrient levels GO:0031669 60 0.023
rna metabolic process GO:0016070 406 0.023
cell projection organization GO:0030030 302 0.023
cellular ketone metabolic process GO:0042180 51 0.023
response to estradiol GO:0032355 164 0.023
brain development GO:0007420 247 0.023
response to organophosphorus GO:0046683 102 0.023
organic anion transport GO:0015711 132 0.023
locomotion GO:0040011 237 0.023
female pregnancy GO:0007565 122 0.023
response to osmotic stress GO:0006970 42 0.022
response to camp GO:0051591 91 0.022
regulation of anatomical structure size GO:0090066 135 0.022
single organism organelle organization GO:1902589 180 0.022
secretion by cell GO:0032940 248 0.022
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
positive regulation of nervous system development GO:0051962 178 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
regulation of cell growth GO:0001558 85 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
positive regulation of molecular function GO:0044093 230 0.021
regulation of neuron projection development GO:0010975 161 0.021
regulation of membrane potential GO:0042391 110 0.021
regulation of secretion by cell GO:1903530 208 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of rna metabolic process GO:0051252 391 0.021
regulation of cell projection organization GO:0031344 175 0.021
insulin secretion GO:0030073 69 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
behavior GO:0007610 205 0.020
response to toxic substance GO:0009636 133 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
response to purine containing compound GO:0014074 126 0.020
regulation of phosphorylation GO:0042325 248 0.020
autophagy GO:0006914 19 0.020
organic acid transport GO:0015849 116 0.019
response to radiation GO:0009314 137 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
synaptic transmission GO:0007268 235 0.019
carbohydrate metabolic process GO:0005975 130 0.019
regulation of neurogenesis GO:0050767 247 0.019
single organism behavior GO:0044708 130 0.019
mapk cascade GO:0000165 140 0.019
hormone transport GO:0009914 121 0.019
neuron development GO:0048666 286 0.019
regulation of peptide hormone secretion GO:0090276 80 0.019
positive regulation of developmental process GO:0051094 283 0.019
positive regulation of cell death GO:0010942 184 0.018
regulation of blood pressure GO:0008217 83 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
developmental growth GO:0048589 100 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cellular response to starvation GO:0009267 27 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of cell development GO:0060284 263 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
cellular amine metabolic process GO:0044106 38 0.018
organelle assembly GO:0070925 22 0.018
multicellular organism growth GO:0035264 1 0.018
organic hydroxy compound transport GO:0015850 77 0.017
multicellular organismal signaling GO:0035637 44 0.017
metal ion homeostasis GO:0055065 186 0.017
multi multicellular organism process GO:0044706 138 0.017
protein localization GO:0008104 191 0.017
response to oxygen levels GO:0070482 265 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
response to reactive oxygen species GO:0000302 120 0.017
neuron projection development GO:0031175 273 0.017
transcription dna templated GO:0006351 377 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
macroautophagy GO:0016236 4 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of hormone secretion GO:0046883 106 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
cellular protein localization GO:0034613 122 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
cardiovascular system development GO:0072358 134 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
ras protein signal transduction GO:0007265 29 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
cellular lipid metabolic process GO:0044255 208 0.016
positive regulation of ion transport GO:0043270 94 0.016
neuron death GO:0070997 127 0.016
negative regulation of molecular function GO:0044092 133 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
localization of cell GO:0051674 202 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
membrane organization GO:0061024 94 0.016
regulation of neuron differentiation GO:0045664 208 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.015
response to nutrient GO:0007584 248 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
circulatory system process GO:0003013 183 0.015
regulation of metal ion transport GO:0010959 118 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
regulation of catabolic process GO:0009894 113 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
calcium ion homeostasis GO:0055074 162 0.015
negative regulation of gene expression GO:0010629 199 0.015
actin filament based process GO:0030029 86 0.015
regulation of synaptic transmission GO:0050804 141 0.015
positive regulation of signal transduction GO:0009967 175 0.015
single organism cellular localization GO:1902580 102 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
negative regulation of signaling GO:0023057 157 0.015
amine metabolic process GO:0009308 38 0.015
epithelium development GO:0060429 96 0.014
establishment of protein localization GO:0045184 141 0.014
peptide transport GO:0015833 97 0.014
glucose homeostasis GO:0042593 75 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
cytoplasmic transport GO:0016482 115 0.014
positive regulation of gene expression GO:0010628 244 0.014
circadian rhythm GO:0007623 88 0.014
carboxylic acid transport GO:0046942 115 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
regulation of protein modification process GO:0031399 194 0.014
amide transport GO:0042886 105 0.014
actin cytoskeleton organization GO:0030036 73 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
heterocycle catabolic process GO:0046700 167 0.014
secretion by tissue GO:0032941 37 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
muscle structure development GO:0061061 87 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
regulation of response to stress GO:0080134 126 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
organic acid biosynthetic process GO:0016053 83 0.014
nucleic acid templated transcription GO:0097659 379 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
transmission of nerve impulse GO:0019226 42 0.013
regulation of neurological system process GO:0031644 43 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
epithelial cell differentiation GO:0030855 71 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
gliogenesis GO:0042063 93 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
cation transmembrane transport GO:0098655 263 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
rhythmic process GO:0048511 156 0.013
lipid transport GO:0006869 61 0.013
divalent inorganic cation transport GO:0072511 134 0.013
spermatogenesis GO:0007283 99 0.013
cytokinetic process GO:0032506 1 0.013
tube development GO:0035295 89 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
negative regulation of transport GO:0051051 136 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
autophagic cell death GO:0048102 4 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of peptide secretion GO:0002791 82 0.013
cellular response to alcohol GO:0097306 87 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of blood vessel size GO:0050880 89 0.012
positive regulation of cell development GO:0010720 176 0.012
peptide hormone secretion GO:0030072 84 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
inflammatory response GO:0006954 150 0.012
intracellular protein transport GO:0006886 79 0.012
muscle system process GO:0003012 115 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
immune system process GO:0002376 204 0.012
response to wounding GO:0009611 254 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
anion transmembrane transport GO:0098656 77 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
hexose metabolic process GO:0019318 58 0.012
divalent metal ion transport GO:0070838 132 0.012
nucleotide metabolic process GO:0009117 279 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
lipid storage GO:0019915 1 0.012
sensory organ development GO:0007423 74 0.011
regulation of homeostatic process GO:0032844 101 0.011
anterior posterior pattern specification GO:0009952 1 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
neuronal action potential GO:0019228 35 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
regulation of calcium ion transport GO:0051924 77 0.011
cognition GO:0050890 92 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
response to ethanol GO:0045471 162 0.011
male gamete generation GO:0048232 99 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
peptide secretion GO:0002790 86 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
regulation of tube size GO:0035150 89 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
response to temperature stimulus GO:0009266 94 0.011
potassium ion transport GO:0006813 97 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
circulatory system development GO:0072359 134 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
rna localization GO:0006403 4 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of mapk cascade GO:0043408 116 0.011
muscle cell proliferation GO:0033002 84 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regeneration GO:0031099 163 0.011
organophosphate biosynthetic process GO:0090407 143 0.010
response to hydrogen peroxide GO:0042542 89 0.010
response to alkaloid GO:0043279 132 0.010
cellular response to oxidative stress GO:0034599 76 0.010
wound healing GO:0042060 122 0.010
response to growth factor GO:0070848 189 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
regulation of insulin secretion GO:0050796 65 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
regulation of transmembrane transport GO:0034762 122 0.010
response to vitamin GO:0033273 131 0.010
reproductive system development GO:0061458 128 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
cell motility GO:0048870 202 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
cellular component movement GO:0006928 248 0.010
maintenance of location GO:0051235 17 0.010

Glul disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
inherited metabolic disorder DOID:655 0 0.018
musculoskeletal system disease DOID:17 0 0.011