Rattus norvegicus

61 known processes

Gphn

gephyrin

(Aliases: Geph)

Gphn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule localization GO:0033036 252 0.152
anion transport GO:0006820 178 0.132
carboxylic acid metabolic process GO:0019752 289 0.119
cellular protein localization GO:0034613 122 0.116
cellular component assembly GO:0022607 360 0.105
transcription dna templated GO:0006351 377 0.101
cellular component biogenesis GO:0044085 368 0.092
reproductive process GO:0022414 372 0.087
protein transport GO:0015031 132 0.085
organelle organization GO:0006996 266 0.084
macromolecular complex subunit organization GO:0043933 339 0.079
single organism reproductive process GO:0044702 297 0.076
regulation of cellular component organization GO:0051128 368 0.075
nucleic acid templated transcription GO:0097659 379 0.071
rna biosynthetic process GO:0032774 380 0.069
protein complex subunit organization GO:0071822 302 0.069
anion transmembrane transport GO:0098656 77 0.064
cellular macromolecule localization GO:0070727 122 0.063
carboxylic acid transport GO:0046942 115 0.061
organic acid metabolic process GO:0006082 292 0.061
intracellular transport GO:0046907 185 0.060
protein localization GO:0008104 191 0.060
single organism biosynthetic process GO:0044711 342 0.058
ion transmembrane transport GO:0034220 365 0.058
regulation of rna biosynthetic process GO:2001141 381 0.057
protein complex biogenesis GO:0070271 263 0.056
oxoacid metabolic process GO:0043436 290 0.055
rna metabolic process GO:0016070 406 0.055
head development GO:0060322 247 0.053
organic anion transport GO:0015711 132 0.053
macromolecular complex assembly GO:0065003 273 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.052
cellular response to endogenous stimulus GO:0071495 377 0.052
positive regulation of biosynthetic process GO:0009891 319 0.050
intracellular protein transport GO:0006886 79 0.049
transcription from rna polymerase ii promoter GO:0006366 252 0.047
protein targeting GO:0006605 61 0.047
cellular response to nitrogen compound GO:1901699 210 0.045
transmembrane transport GO:0055085 412 0.045
protein homooligomerization GO:0051260 91 0.045
small molecule biosynthetic process GO:0044283 124 0.044
protein complex assembly GO:0006461 263 0.044
monocarboxylic acid transport GO:0015718 52 0.044
multicellular organismal reproductive process GO:0048609 233 0.043
brain development GO:0007420 247 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
reproduction GO:0000003 245 0.042
multi organism reproductive process GO:0044703 262 0.041
protein oligomerization GO:0051259 191 0.040
multicellular organism reproduction GO:0032504 233 0.040
positive regulation of cell communication GO:0010647 271 0.038
cellular response to organic cyclic compound GO:0071407 202 0.038
response to peptide hormone GO:0043434 278 0.038
g protein coupled receptor signaling pathway GO:0007186 242 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
response to inorganic substance GO:0010035 377 0.038
cellular response to cytokine stimulus GO:0071345 127 0.037
positive regulation of signaling GO:0023056 270 0.037
response to extracellular stimulus GO:0009991 380 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
chemical homeostasis GO:0048878 292 0.035
neurological system process GO:0050877 219 0.034
cellular ketone metabolic process GO:0042180 51 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
nitrogen compound transport GO:0071705 229 0.033
intracellular signal transduction GO:0035556 314 0.033
secretion GO:0046903 307 0.032
single organism cellular localization GO:1902580 102 0.032
neuron differentiation GO:0030182 368 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
rhythmic process GO:0048511 156 0.031
regulation of secretion GO:0051046 224 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
response to nutrient GO:0007584 248 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
response to growth factor GO:0070848 189 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
response to carbohydrate GO:0009743 183 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
cellular homeostasis GO:0019725 252 0.029
organic acid transport GO:0015849 116 0.029
establishment of protein localization GO:0045184 141 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
response to monosaccharide GO:0034284 159 0.028
regulation of cellular localization GO:0060341 263 0.028
monovalent inorganic cation transport GO:0015672 172 0.028
regulation of rna metabolic process GO:0051252 391 0.028
negative regulation of transport GO:0051051 136 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
regulation of protein metabolic process GO:0051246 289 0.027
positive regulation of gene expression GO:0010628 244 0.027
cytoplasmic transport GO:0016482 115 0.027
regulation of signal transduction GO:0009966 318 0.027
cellular amine metabolic process GO:0044106 38 0.027
metal ion transport GO:0030001 289 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.026
inorganic ion transmembrane transport GO:0098660 229 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
response to peptide GO:1901652 292 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
lipid metabolic process GO:0006629 283 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
regulation of cell development GO:0060284 263 0.024
regulation of transcription dna templated GO:0006355 374 0.023
secretion by cell GO:0032940 248 0.023
peptidyl amino acid modification GO:0018193 126 0.023
neuron development GO:0048666 286 0.023
organic acid biosynthetic process GO:0016053 83 0.023
response to nutrient levels GO:0031667 370 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
negative regulation of metabolic process GO:0009892 331 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cell cell signaling GO:0007267 335 0.022
establishment of protein localization to organelle GO:0072594 44 0.022
regulation of cell differentiation GO:0045595 320 0.022
regulation of neuron differentiation GO:0045664 208 0.022
central nervous system development GO:0007417 311 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
growth GO:0040007 165 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
response to cytokine GO:0034097 215 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
amine metabolic process GO:0009308 38 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
dephosphorylation GO:0016311 98 0.020
neuron neuron synaptic transmission GO:0007270 60 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
lipid biosynthetic process GO:0008610 128 0.020
immune response GO:0006955 104 0.020
startle response GO:0001964 2 0.020
protein dephosphorylation GO:0006470 38 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of protein localization GO:0032880 81 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
cellular catabolic process GO:0044248 295 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
single organism intracellular transport GO:1902582 166 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
synaptic transmission GO:0007268 235 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
lipid transport GO:0006869 61 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
response to toxic substance GO:0009636 133 0.018
ion homeostasis GO:0050801 212 0.018
regulation of molecular function GO:0065009 398 0.018
regulation of ion transport GO:0043269 245 0.018
homeostatic process GO:0042592 331 0.018
regulation of phosphorylation GO:0042325 248 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of hormone levels GO:0010817 187 0.018
positive regulation of secretion GO:0051047 140 0.018
regulation of protein transport GO:0051223 68 0.018
response to purine containing compound GO:0014074 126 0.018
response to glucose GO:0009749 136 0.018
response to metal ion GO:0010038 253 0.018
ribose phosphate metabolic process GO:0019693 235 0.017
response to ammonium ion GO:0060359 71 0.017
proteolysis GO:0006508 175 0.017
cellular response to stress GO:0033554 269 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
chromosome segregation GO:0007059 2 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
regulation of secretion by cell GO:1903530 208 0.017
regulation of cell proliferation GO:0042127 359 0.017
response to corticosteroid GO:0031960 235 0.017
behavior GO:0007610 205 0.017
response to interleukin 15 GO:0070672 4 0.016
peptide transport GO:0015833 97 0.016
single organism catabolic process GO:0044712 283 0.016
regulation of peptide transport GO:0090087 87 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
cation transport GO:0006812 382 0.016
positive regulation of cell development GO:0010720 176 0.016
response to ketone GO:1901654 182 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
purine containing compound biosynthetic process GO:0072522 85 0.015
regulation of apoptotic process GO:0042981 335 0.015
response to other organism GO:0051707 220 0.015
protein phosphorylation GO:0006468 345 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
metal ion homeostasis GO:0055065 186 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of organelle organization GO:0033043 80 0.015
programmed cell death GO:0012501 392 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cation homeostasis GO:0055080 195 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
asymmetric protein localization GO:0008105 2 0.015
multicellular organismal signaling GO:0035637 44 0.015
cellular cation homeostasis GO:0030003 180 0.015
negative regulation of gene expression GO:0010629 199 0.015
regulation of nervous system development GO:0051960 264 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
carbohydrate metabolic process GO:0005975 130 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of protein targeting GO:1903533 28 0.014
response to alkaloid GO:0043279 132 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
synaptic transmission gabaergic GO:0051932 22 0.014
cellular response to ammonium ion GO:0071242 17 0.014
synaptic transmission glycinergic GO:0060012 2 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of cellular component movement GO:0051270 150 0.014
response to bacterium GO:0009617 200 0.014
response to glucocorticoid GO:0051384 223 0.014
single organism organelle organization GO:1902589 180 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
response to reactive oxygen species GO:0000302 120 0.014
lipid localization GO:0010876 62 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
regulation of anion transport GO:0044070 43 0.014
cell projection organization GO:0030030 302 0.014
synapse organization GO:0050808 46 0.014
cell adhesion GO:0007155 110 0.013
biological adhesion GO:0022610 110 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
ras protein signal transduction GO:0007265 29 0.013
anterior posterior pattern specification GO:0009952 1 0.013
embryonic pattern specification GO:0009880 1 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
nuclear transport GO:0051169 49 0.013
protein localization to organelle GO:0033365 57 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of secretion GO:0051048 82 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
defense response GO:0006952 194 0.013
thioester metabolic process GO:0035383 28 0.013
ovulation cycle GO:0042698 67 0.013
protein localization to nucleus GO:0034504 39 0.012
immune system process GO:0002376 204 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
negative regulation of signal transduction GO:0009968 83 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of protein import into nucleus GO:0042306 24 0.012
positive regulation of molecular function GO:0044093 230 0.012
regulation of neurogenesis GO:0050767 247 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
regulation of membrane potential GO:0042391 110 0.012
negative regulation of developmental process GO:0051093 125 0.012
locomotion GO:0040011 237 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
neuron projection development GO:0031175 273 0.012
response to oxygen levels GO:0070482 265 0.012
positive regulation of transport GO:0051050 245 0.012
gamete generation GO:0007276 124 0.012
sexual reproduction GO:0019953 148 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
regulation of protein modification process GO:0031399 194 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
response to insulin GO:0032868 133 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
fatty acid transport GO:0015908 25 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of locomotion GO:0040012 148 0.012
response to ethanol GO:0045471 162 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cellular component morphogenesis GO:0032989 155 0.011
fatty acid metabolic process GO:0006631 99 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
response to lipopolysaccharide GO:0032496 191 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
female pregnancy GO:0007565 122 0.011
dna metabolic process GO:0006259 96 0.011
small molecule catabolic process GO:0044282 59 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cellular response to histamine GO:0071420 3 0.011
synapse assembly GO:0007416 29 0.011
gland development GO:0048732 155 0.011
cellular response to peptide GO:1901653 133 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
apoptotic process GO:0006915 381 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
regulation of neuron projection development GO:0010975 161 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
positive regulation of protein modification process GO:0031401 142 0.011
carbohydrate homeostasis GO:0033500 75 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
nucleoside metabolic process GO:0009116 179 0.011
regulation of homeostatic process GO:0032844 101 0.011
organic substance catabolic process GO:1901575 316 0.011
regulation of programmed cell death GO:0043067 341 0.011
regulation of response to external stimulus GO:0032101 106 0.011
positive regulation of nervous system development GO:0051962 178 0.011
chromosome organization GO:0051276 36 0.011
negative regulation of cell projection organization GO:0031345 50 0.010
jak stat cascade GO:0007259 26 0.010
negative regulation of protein transport GO:0051224 17 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of dna metabolic process GO:0051052 60 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
response to fatty acid GO:0070542 65 0.010
protein autophosphorylation GO:0046777 66 0.010
response to hexose GO:0009746 144 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
neurotrophin trk receptor signaling pathway GO:0048011 10 0.010
nucleocytoplasmic transport GO:0006913 48 0.010
protein heterooligomerization GO:0051291 89 0.010
cellular ion homeostasis GO:0006873 184 0.010
positive regulation of cell death GO:0010942 184 0.010
nucleotide metabolic process GO:0009117 279 0.010

Gphn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.018
retinal disease DOID:5679 0 0.017
retinal degeneration DOID:8466 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
muscular disease DOID:0080000 0 0.013
inherited metabolic disorder DOID:655 0 0.012