Rattus norvegicus

75 known processes

Gpx1

glutathione peroxidase 1

(Aliases: GSHPx-1,GSHPx)

Gpx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.446
response to bacterium GO:0009617 200 0.240
response to inorganic substance GO:0010035 377 0.200
cellular response to oxygen containing compound GO:1901701 386 0.194
macromolecular complex assembly GO:0065003 273 0.190
carboxylic acid metabolic process GO:0019752 289 0.175
fatty acid metabolic process GO:0006631 99 0.173
lipid metabolic process GO:0006629 283 0.158
response to amino acid GO:0043200 75 0.156
intracellular transport GO:0046907 185 0.150
negative regulation of cell death GO:0060548 229 0.148
response to oxidative stress GO:0006979 186 0.146
monocarboxylic acid metabolic process GO:0032787 152 0.133
homeostatic process GO:0042592 331 0.132
organic acid metabolic process GO:0006082 292 0.128
cellular component assembly GO:0022607 360 0.123
response to wounding GO:0009611 254 0.119
chemical homeostasis GO:0048878 292 0.119
response to estradiol GO:0032355 164 0.117
protein complex assembly GO:0006461 263 0.112
single organism reproductive process GO:0044702 297 0.112
response to molecule of bacterial origin GO:0002237 194 0.111
response to metal ion GO:0010038 253 0.109
reproductive process GO:0022414 372 0.108
response to peptide GO:1901652 292 0.104
response to external biotic stimulus GO:0043207 221 0.101
sulfur compound metabolic process GO:0006790 70 0.101
positive regulation of cell proliferation GO:0008284 249 0.094
cellular amino acid metabolic process GO:0006520 107 0.089
regulation of catalytic activity GO:0050790 304 0.087
multicellular organism reproduction GO:0032504 233 0.087
ion homeostasis GO:0050801 212 0.085
regulation of molecular function GO:0065009 398 0.084
single organism biosynthetic process GO:0044711 342 0.082
defense response GO:0006952 194 0.082
cellular response to reactive oxygen species GO:0034614 55 0.082
positive regulation of cell communication GO:0010647 271 0.081
cellular amide metabolic process GO:0043603 44 0.078
regulation of cell proliferation GO:0042127 359 0.077
response to other organism GO:0051707 220 0.077
response to estrogen GO:0043627 232 0.076
regeneration GO:0031099 163 0.074
response to nutrient GO:0007584 248 0.072
organic acid biosynthetic process GO:0016053 83 0.070
response to glucocorticoid GO:0051384 223 0.069
programmed cell death GO:0012501 392 0.069
regulation of multicellular organismal development GO:2000026 376 0.069
regulation of programmed cell death GO:0043067 341 0.067
metal ion transport GO:0030001 289 0.066
regulation of apoptotic process GO:0042981 335 0.064
regulation of phosphate metabolic process GO:0019220 349 0.063
positive regulation of cellular protein metabolic process GO:0032270 167 0.062
response to reactive oxygen species GO:0000302 120 0.061
response to acid chemical GO:0001101 222 0.060
negative regulation of apoptotic process GO:0043066 181 0.060
macromolecule localization GO:0033036 252 0.059
aging GO:0007568 241 0.058
single organism intracellular transport GO:1902582 166 0.056
small molecule biosynthetic process GO:0044283 124 0.055
regulation of hormone levels GO:0010817 187 0.055
positive regulation of signal transduction GO:0009967 175 0.053
organ regeneration GO:0031100 101 0.053
protein phosphorylation GO:0006468 345 0.052
cellular response to endogenous stimulus GO:0071495 377 0.052
oxoacid metabolic process GO:0043436 290 0.051
cation transmembrane transport GO:0098655 263 0.051
tissue development GO:0009888 252 0.051
cellular component biogenesis GO:0044085 368 0.050
oxidation reduction process GO:0055114 304 0.050
response to nutrient levels GO:0031667 370 0.048
regulation of cellular component movement GO:0051270 150 0.047
regulation of cell development GO:0060284 263 0.047
cellular lipid metabolic process GO:0044255 208 0.046
wound healing GO:0042060 122 0.046
protein complex subunit organization GO:0071822 302 0.046
gamete generation GO:0007276 124 0.046
cellular ketone metabolic process GO:0042180 51 0.045
neuron development GO:0048666 286 0.045
localization of cell GO:0051674 202 0.045
response to hydrogen peroxide GO:0042542 89 0.045
protein oligomerization GO:0051259 191 0.045
reactive oxygen species metabolic process GO:0072593 37 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
negative regulation of metabolic process GO:0009892 331 0.044
apoptotic process GO:0006915 381 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
positive regulation of cell death GO:0010942 184 0.043
cellular component movement GO:0006928 248 0.042
response to axon injury GO:0048678 59 0.042
response to vitamin GO:0033273 131 0.040
regulation of cell differentiation GO:0045595 320 0.040
developmental process involved in reproduction GO:0003006 159 0.039
positive regulation of signaling GO:0023056 270 0.039
reproduction GO:0000003 245 0.039
cell projection organization GO:0030030 302 0.039
response to toxic substance GO:0009636 133 0.038
central nervous system development GO:0007417 311 0.037
head development GO:0060322 247 0.037
positive regulation of neurogenesis GO:0050769 165 0.037
organonitrogen compound biosynthetic process GO:1901566 167 0.037
cellular response to oxidative stress GO:0034599 76 0.036
cellular homeostasis GO:0019725 252 0.035
negative regulation of programmed cell death GO:0043069 183 0.035
cellular response to stress GO:0033554 269 0.034
anatomical structure morphogenesis GO:0009653 298 0.034
biological adhesion GO:0022610 110 0.034
cellular catabolic process GO:0044248 295 0.034
secretion GO:0046903 307 0.033
cell activation GO:0001775 97 0.033
lipid biosynthetic process GO:0008610 128 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.032
peptide metabolic process GO:0006518 32 0.032
response to peptide hormone GO:0043434 278 0.032
positive regulation of response to stimulus GO:0048584 285 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
cellular modified amino acid metabolic process GO:0006575 61 0.031
synaptic transmission GO:0007268 235 0.031
cellular response to metal ion GO:0071248 55 0.031
regulation of protein metabolic process GO:0051246 289 0.031
regulation of protein phosphorylation GO:0001932 183 0.030
ion transmembrane transport GO:0034220 365 0.030
protein complex biogenesis GO:0070271 263 0.030
sexual reproduction GO:0019953 148 0.030
response to transition metal nanoparticle GO:1990267 122 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
neuron projection development GO:0031175 273 0.029
regulation of cellular component organization GO:0051128 368 0.029
gland development GO:0048732 155 0.029
regulation of cell migration GO:0030334 128 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
carbohydrate metabolic process GO:0005975 130 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
organelle organization GO:0006996 266 0.028
response to extracellular stimulus GO:0009991 380 0.027
membrane organization GO:0061024 94 0.027
regulation of response to wounding GO:1903034 69 0.027
locomotion GO:0040011 237 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
regulation of phosphorylation GO:0042325 248 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.026
protein localization GO:0008104 191 0.026
leydig cell differentiation GO:0033327 8 0.026
neuron differentiation GO:0030182 368 0.026
regulation of body fluid levels GO:0050878 90 0.025
reproductive system development GO:0061458 128 0.025
regulation of neurogenesis GO:0050767 247 0.025
cellular chemical homeostasis GO:0055082 247 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
calcium ion transport GO:0006816 131 0.024
cofactor metabolic process GO:0051186 95 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
nucleotide metabolic process GO:0009117 279 0.023
regulation of ion transport GO:0043269 245 0.023
glial cell differentiation GO:0010001 65 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
cellular response to lipid GO:0071396 201 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
reproductive structure development GO:0048608 128 0.023
cation transport GO:0006812 382 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
immune system process GO:0002376 204 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
carboxylic acid biosynthetic process GO:0046394 83 0.023
negative regulation of catalytic activity GO:0043086 103 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
response to ketone GO:1901654 182 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
regulation of nervous system development GO:0051960 264 0.022
response to biotic stimulus GO:0009607 226 0.022
response to ethanol GO:0045471 162 0.022
spermatogenesis GO:0007283 99 0.022
regulation of synaptic transmission GO:0050804 141 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of cell motility GO:2000145 131 0.022
single organismal cell cell adhesion GO:0016337 42 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
male gamete generation GO:0048232 99 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of secretion by cell GO:1903530 208 0.021
cellular macromolecule localization GO:0070727 122 0.021
cellular hormone metabolic process GO:0034754 49 0.021
single organism catabolic process GO:0044712 283 0.020
positive regulation of cell motility GO:2000147 97 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of developmental process GO:0051094 283 0.020
cardiovascular system development GO:0072358 134 0.020
rhythmic process GO:0048511 156 0.020
axon development GO:0061564 96 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
organic substance catabolic process GO:1901575 316 0.020
nitrogen compound transport GO:0071705 229 0.019
cell growth GO:0016049 104 0.019
protein homooligomerization GO:0051260 91 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
cation homeostasis GO:0055080 195 0.019
response to lipopolysaccharide GO:0032496 191 0.018
fatty acid derivative metabolic process GO:1901568 38 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
hormone metabolic process GO:0042445 69 0.018
catabolic process GO:0009056 351 0.018
response to cytokine GO:0034097 215 0.018
positive regulation of gene expression GO:0010628 244 0.018
response to corticosteroid GO:0031960 235 0.017
leukocyte activation GO:0045321 76 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
single organism cellular localization GO:1902580 102 0.017
sensory organ development GO:0007423 74 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
single organism membrane organization GO:0044802 74 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
response to amine GO:0014075 46 0.016
epithelium development GO:0060429 96 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
regulation of locomotion GO:0040012 148 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
dna metabolic process GO:0006259 96 0.016
positive regulation of transport GO:0051050 245 0.016
amine metabolic process GO:0009308 38 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
response to testosterone GO:0033574 55 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
female pregnancy GO:0007565 122 0.015
secretion by cell GO:0032940 248 0.015
response to oxygen levels GO:0070482 265 0.015
inflammatory response GO:0006954 150 0.015
intracellular signal transduction GO:0035556 314 0.015
mapk cascade GO:0000165 140 0.015
rna metabolic process GO:0016070 406 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
positive regulation of molecular function GO:0044093 230 0.015
nucleoside monophosphate metabolic process GO:0009123 93 0.015
positive regulation of protein kinase activity GO:0045860 73 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular amine metabolic process GO:0044106 38 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
response to insulin GO:0032868 133 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cell cell signaling GO:0007267 335 0.014
urogenital system development GO:0001655 78 0.014
protein tetramerization GO:0051262 38 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
positive regulation of cell migration GO:0030335 96 0.014
positive regulation of nervous system development GO:0051962 178 0.014
gliogenesis GO:0042063 93 0.013
brain development GO:0007420 247 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of protein modification process GO:0031399 194 0.013
protein targeting GO:0006605 61 0.013
metal ion homeostasis GO:0055065 186 0.013
nucleic acid templated transcription GO:0097659 379 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of protein kinase activity GO:0045859 105 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
cell morphogenesis GO:0000902 142 0.013
positive regulation of cell development GO:0010720 176 0.013
regulation of cell growth GO:0001558 85 0.013
protein transport GO:0015031 132 0.013
response to hexose GO:0009746 144 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
negative regulation of gene expression GO:0010629 199 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of immune response GO:0050776 55 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
rna localization GO:0006403 4 0.013
negative regulation of molecular function GO:0044092 133 0.013
organic cyclic compound catabolic process GO:1901361 175 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
signal release GO:0023061 145 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of defense response GO:0031347 68 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
cellular component morphogenesis GO:0032989 155 0.012
regulation of signal transduction GO:0009966 318 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
sex differentiation GO:0007548 113 0.012
cellular protein localization GO:0034613 122 0.012
behavior GO:0007610 205 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
response to lead ion GO:0010288 33 0.012
regulation of response to external stimulus GO:0032101 106 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
anatomical structure homeostasis GO:0060249 29 0.012
fatty acid biosynthetic process GO:0006633 33 0.012
development of primary sexual characteristics GO:0045137 107 0.011
hemopoiesis GO:0030097 34 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
purine containing compound metabolic process GO:0072521 253 0.011
regulation of cellular localization GO:0060341 263 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
response to retinoic acid GO:0032526 63 0.011
regulation of cellular component size GO:0032535 51 0.011
peptidyl amino acid modification GO:0018193 126 0.011
heterocycle catabolic process GO:0046700 167 0.011
gonad development GO:0008406 104 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
negative regulation of cell development GO:0010721 82 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
hydrogen peroxide metabolic process GO:0042743 13 0.011
protein homotetramerization GO:0051289 25 0.011
negative regulation of cell communication GO:0010648 158 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
single organism behavior GO:0044708 130 0.010
response to hypoxia GO:0001666 231 0.010
response to osmotic stress GO:0006970 42 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
rna biosynthetic process GO:0032774 380 0.010
cytoplasmic transport GO:0016482 115 0.010
anion transport GO:0006820 178 0.010
divalent inorganic cation transport GO:0072511 134 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
cellular response to external stimulus GO:0071496 118 0.010
alpha amino acid biosynthetic process GO:1901607 23 0.010
response to monosaccharide GO:0034284 159 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010

Gpx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.012