Rattus norvegicus

115 known processes

Grb10

growth factor receptor bound protein 10

(Aliases: RGD1566234)

Grb10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.244
cellular response to endogenous stimulus GO:0071495 377 0.105
nucleic acid templated transcription GO:0097659 379 0.098
neuron differentiation GO:0030182 368 0.082
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.079
response to nutrient levels GO:0031667 370 0.077
response to extracellular stimulus GO:0009991 380 0.075
negative regulation of metabolic process GO:0009892 331 0.075
rna biosynthetic process GO:0032774 380 0.073
cellular response to peptide GO:1901653 133 0.073
transcription dna templated GO:0006351 377 0.072
negative regulation of cellular metabolic process GO:0031324 281 0.071
regulation of nervous system development GO:0051960 264 0.070
regulation of transcription dna templated GO:0006355 374 0.068
cardiac chamber development GO:0003205 1 0.066
regulation of rna metabolic process GO:0051252 391 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.064
regulation of cellular component organization GO:0051128 368 0.063
regulation of stem cell differentiation GO:2000736 2 0.060
cellular response to nitrogen compound GO:1901699 210 0.056
regulation of neurogenesis GO:0050767 247 0.056
cardiovascular system development GO:0072358 134 0.055
regulation of nucleic acid templated transcription GO:1903506 380 0.054
regulation of multicellular organismal development GO:2000026 376 0.052
multicellular organismal reproductive process GO:0048609 233 0.052
Worm
cellular response to lipid GO:0071396 201 0.049
regulation of cell differentiation GO:0045595 320 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.046
neuron development GO:0048666 286 0.043
Worm
regulation of rna biosynthetic process GO:2001141 381 0.043
response to acid chemical GO:0001101 222 0.043
response to cytokine GO:0034097 215 0.043
positive regulation of gene expression GO:0010628 244 0.042
single organism reproductive process GO:0044702 297 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
response to inorganic substance GO:0010035 377 0.042
cardiac ventricle development GO:0003231 1 0.041
positive regulation of molecular function GO:0044093 230 0.041
positive regulation of cell communication GO:0010647 271 0.041
Human Mouse
multi organism reproductive process GO:0044703 262 0.041
Worm
cellular response to hormone stimulus GO:0032870 247 0.041
response to decreased oxygen levels GO:0036293 237 0.040
cell projection organization GO:0030030 302 0.038
Worm
cellular response to cytokine stimulus GO:0071345 127 0.037
cellular response to oxygen containing compound GO:1901701 386 0.036
cellular component biogenesis GO:0044085 368 0.036
Worm
bmp signaling pathway GO:0030509 4 0.036
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
multicellular organism reproduction GO:0032504 233 0.035
Worm
regulation of neuron differentiation GO:0045664 208 0.034
reproduction GO:0000003 245 0.034
Worm
response to oxygen levels GO:0070482 265 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.033
salivary gland development GO:0007431 3 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
regulation of cell development GO:0060284 263 0.032
homeostatic process GO:0042592 331 0.032
reproductive process GO:0022414 372 0.032
Worm
regulation of phosphorus metabolic process GO:0051174 349 0.032
negative regulation of rna biosynthetic process GO:1902679 118 0.031
cellular component assembly GO:0022607 360 0.031
Worm
regulation of molecular function GO:0065009 398 0.031
negative regulation of rna metabolic process GO:0051253 123 0.031
aging GO:0007568 241 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
oxidation reduction process GO:0055114 304 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
localization of cell GO:0051674 202 0.030
Worm
cellular calcium ion homeostasis GO:0006874 160 0.030
negative regulation of multicellular organismal process GO:0051241 203 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
sexual reproduction GO:0019953 148 0.029
organelle organization GO:0006996 266 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
regulation of programmed cell death GO:0043067 341 0.029
regulation of bmp signaling pathway GO:0030510 2 0.028
neural crest cell differentiation GO:0014033 2 0.028
cation transport GO:0006812 382 0.028
negative regulation of transcription dna templated GO:0045892 116 0.028
secretion by cell GO:0032940 248 0.027
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of nervous system development GO:0051962 178 0.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.027
organic acid metabolic process GO:0006082 292 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
regulation of apoptotic process GO:0042981 335 0.027
brain development GO:0007420 247 0.027
negative regulation of gene expression GO:0010629 199 0.027
response to peptide hormone GO:0043434 278 0.026
tissue development GO:0009888 252 0.026
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
regulation of membrane potential GO:0042391 110 0.026
response to hypoxia GO:0001666 231 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
macromolecule localization GO:0033036 252 0.026
protein complex subunit organization GO:0071822 302 0.025
response to growth factor GO:0070848 189 0.025
Human
response to hexose GO:0009746 144 0.025
secretion GO:0046903 307 0.025
growth GO:0040007 165 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
cell cell signaling GO:0007267 335 0.025
regulation of canonical wnt signaling pathway GO:0060828 4 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
negative regulation of cell development GO:0010721 82 0.025
cell morphogenesis GO:0000902 142 0.025
Worm
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
regulation of signal transduction GO:0009966 318 0.024
Human Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
response to nutrient GO:0007584 248 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
heart morphogenesis GO:0003007 3 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
regulation of neuron apoptotic process GO:0043523 83 0.023
single organism organelle organization GO:1902589 180 0.023
single organism intracellular transport GO:1902582 166 0.023
cellular amine metabolic process GO:0044106 38 0.023
calcium ion homeostasis GO:0055074 162 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of cell death GO:0060548 229 0.022
dendrite development GO:0016358 72 0.022
negative regulation of cell communication GO:0010648 158 0.022
Human Mouse Rat
negative regulation of biosynthetic process GO:0009890 168 0.022
behavior GO:0007610 205 0.022
Worm
positive regulation of cellular component organization GO:0051130 200 0.022
cellular chemical homeostasis GO:0055082 247 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
regulation of cellular localization GO:0060341 263 0.022
positive regulation of developmental process GO:0051094 283 0.022
alpha amino acid metabolic process GO:1901605 71 0.022
response to carbohydrate GO:0009743 183 0.021
embryonic skeletal system development GO:0048706 3 0.021
programmed cell death GO:0012501 392 0.021
cellular ion homeostasis GO:0006873 184 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
chemical homeostasis GO:0048878 292 0.021
intracellular signal transduction GO:0035556 314 0.021
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.021
intracellular protein transport GO:0006886 79 0.021
immune response GO:0006955 104 0.021
cell cycle GO:0007049 101 0.021
neurological system process GO:0050877 219 0.021
cellular homeostasis GO:0019725 252 0.021
neuron projection development GO:0031175 273 0.021
Worm
negative regulation of signaling GO:0023057 157 0.021
Human Mouse Rat
central nervous system development GO:0007417 311 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
axis specification GO:0009798 4 0.020
response to estrogen GO:0043627 232 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
Worm
response to peptide GO:1901652 292 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
positive regulation of cell death GO:0010942 184 0.020
ion homeostasis GO:0050801 212 0.020
gamete generation GO:0007276 124 0.020
negative regulation of immune system process GO:0002683 39 0.020
regulation of neuron projection development GO:0010975 161 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of signaling GO:0023056 270 0.020
Human Mouse
cellular component movement GO:0006928 248 0.020
Worm
metal ion transport GO:0030001 289 0.020
type b pancreatic cell proliferation GO:0044342 3 0.020
metal ion homeostasis GO:0055065 186 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
regulation of secretion GO:0051046 224 0.020
immune system process GO:0002376 204 0.020
response to retinoic acid GO:0032526 63 0.019
regulation of cell projection organization GO:0031344 175 0.019
organophosphate metabolic process GO:0019637 370 0.019
ion transmembrane transport GO:0034220 365 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to ketone GO:1901654 182 0.019
cellular response to stress GO:0033554 269 0.019
Worm
salivary gland morphogenesis GO:0007435 1 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
negative regulation of response to stimulus GO:0048585 155 0.018
Human Mouse Rat
regulation of cellular amine metabolic process GO:0033238 8 0.018
mesoderm development GO:0007498 2 0.018
Worm
protein localization GO:0008104 191 0.018
organic substance catabolic process GO:1901575 316 0.018
protein phosphorylation GO:0006468 345 0.018
locomotion GO:0040011 237 0.018
Worm
organonitrogen compound biosynthetic process GO:1901566 167 0.018
protein transport GO:0015031 132 0.018
apoptotic process GO:0006915 381 0.018
establishment of protein localization GO:0045184 141 0.017
ossification GO:0001503 70 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
catabolic process GO:0009056 351 0.017
regulation of phosphorylation GO:0042325 248 0.017
regulation of catalytic activity GO:0050790 304 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
cellular cation homeostasis GO:0030003 180 0.017
developmental growth GO:0048589 100 0.017
regulation of phosphate metabolic process GO:0019220 349 0.016
head development GO:0060322 247 0.016
response to biotic stimulus GO:0009607 226 0.016
hair follicle development GO:0001942 2 0.016
wound healing GO:0042060 122 0.016
regulation of establishment of planar polarity GO:0090175 2 0.016
cell projection morphogenesis GO:0048858 123 0.016
Worm
ras protein signal transduction GO:0007265 29 0.016
establishment of tissue polarity GO:0007164 2 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
cytoplasmic transport GO:0016482 115 0.016
embryonic pattern specification GO:0009880 1 0.016
cation homeostasis GO:0055080 195 0.016
defense response GO:0006952 194 0.015
regeneration GO:0031099 163 0.015
Worm
cellular response to acid chemical GO:0071229 75 0.015
single organism biosynthetic process GO:0044711 342 0.015
nucleotide metabolic process GO:0009117 279 0.015
synaptic transmission GO:0007268 235 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
inflammatory response GO:0006954 150 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of protein metabolic process GO:0051246 289 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
regulation of dendrite development GO:0050773 59 0.015
response to wounding GO:0009611 254 0.015
Worm
regulation of intracellular signal transduction GO:1902531 218 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
forebrain development GO:0030900 98 0.015
cellular response to external stimulus GO:0071496 118 0.015
hair cycle GO:0042633 3 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of neuron death GO:1901214 115 0.015
cellular component morphogenesis GO:0032989 155 0.015
Worm
cell motility GO:0048870 202 0.015
Worm
neuron death GO:0070997 127 0.015
rhythmic process GO:0048511 156 0.015
cell migration GO:0016477 197 0.014
Worm
anterior posterior pattern specification GO:0009952 1 0.014
neuronal action potential GO:0019228 35 0.014
circulatory system development GO:0072359 134 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
signal release GO:0023061 145 0.014
taxis GO:0042330 67 0.014
epithelial cell differentiation GO:0030855 71 0.014
response to lipopolysaccharide GO:0032496 191 0.014
negative regulation of molecular function GO:0044092 133 0.014
hair cycle process GO:0022405 2 0.014
biological adhesion GO:0022610 110 0.014
response to monosaccharide GO:0034284 159 0.014
tissue remodeling GO:0048771 40 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
regulation of cell cycle GO:0051726 73 0.014
cellular ketone metabolic process GO:0042180 51 0.014
cell part morphogenesis GO:0032990 123 0.014
Worm
macromolecular complex subunit organization GO:0043933 339 0.014
response to glucose GO:0009749 136 0.014
response to oxidative stress GO:0006979 186 0.014
mapk cascade GO:0000165 140 0.014
peptidyl amino acid modification GO:0018193 126 0.014
synapse organization GO:0050808 46 0.014
positive regulation of cell development GO:0010720 176 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
microtubule organizing center organization GO:0031023 1 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
Human
spermatogenesis GO:0007283 99 0.013
response to radiation GO:0009314 137 0.013
molting cycle process GO:0022404 2 0.013
multi multicellular organism process GO:0044706 138 0.013
Worm
male gamete generation GO:0048232 99 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cation transmembrane transport GO:0098655 263 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
protein complex assembly GO:0006461 263 0.013
kidney development GO:0001822 67 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of signal transduction GO:0009967 175 0.013
Human Mouse
intracellular transport GO:0046907 185 0.013
gastrulation GO:0007369 2 0.013
Worm
organophosphate biosynthetic process GO:0090407 143 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
action potential GO:0001508 54 0.013
regulation of kinase activity GO:0043549 117 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
oxoacid metabolic process GO:0043436 290 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
neuron apoptotic process GO:0051402 88 0.013
neural crest cell development GO:0014032 2 0.013
eye morphogenesis GO:0048592 4 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
negative regulation of signal transduction GO:0009968 83 0.012
Human Mouse Rat
regulation of metal ion transport GO:0010959 118 0.012
response to purine containing compound GO:0014074 126 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
endocytosis GO:0006897 84 0.012
multicellular organismal signaling GO:0035637 44 0.012
developmental process involved in reproduction GO:0003006 159 0.012
protein localization to organelle GO:0033365 57 0.012
single organism behavior GO:0044708 130 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.012
cell cycle process GO:0022402 57 0.012
maintenance of location GO:0051235 17 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
embryonic neurocranium morphogenesis GO:0048702 2 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
male mating behavior GO:0060179 3 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
gonad development GO:0008406 104 0.012
glucose metabolic process GO:0006006 52 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
regulation of embryonic development GO:0045995 2 0.012
embryonic skeletal system morphogenesis GO:0048704 3 0.012
regulation of immune system process GO:0002682 123 0.012
actin cytoskeleton organization GO:0030036 73 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cell adhesion GO:0007155 110 0.012
blood circulation GO:0008015 183 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.011
cell fate determination GO:0001709 2 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
divalent inorganic cation transport GO:0072511 134 0.011
heart valve morphogenesis GO:0003179 1 0.011
hexose metabolic process GO:0019318 58 0.011
response to metal ion GO:0010038 253 0.011
regulation of hydrolase activity GO:0051336 143 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
spindle organization GO:0007051 2 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
gland development GO:0048732 155 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cellular catabolic process GO:0044248 295 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
protein complex biogenesis GO:0070271 263 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
actin filament based process GO:0030029 86 0.011
single organism catabolic process GO:0044712 283 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
negative regulation of developmental process GO:0051093 125 0.011
calcium ion transport GO:0006816 131 0.011
circulatory system process GO:0003013 183 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
heart development GO:0007507 72 0.011
positive regulation of response to stimulus GO:0048584 285 0.010
Human Mouse
mitotic spindle organization GO:0007052 2 0.010
cytoskeleton organization GO:0007010 111 0.010
skin morphogenesis GO:0043589 2 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
lipid metabolic process GO:0006629 283 0.010
regulation of system process GO:0044057 208 0.010
motor neuron axon guidance GO:0008045 1 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
response to starvation GO:0042594 59 0.010
positive regulation of protein modification process GO:0031401 142 0.010
negative regulation of monooxygenase activity GO:0032769 3 0.010
adult locomotory behavior GO:0008344 4 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010

Grb10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.025
disease of anatomical entity DOID:7 0 0.025
muscular disease DOID:0080000 0 0.016
nervous system disease DOID:863 0 0.015
muscle tissue disease DOID:66 0 0.013
muscular dystrophy DOID:9884 0 0.012
myopathy DOID:423 0 0.012
central nervous system disease DOID:331 0 0.010