Rattus norvegicus

0 known processes

Grm4

glutamate receptor, metabotropic 4

Grm4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.273
homeostatic process GO:0042592 331 0.250
monovalent inorganic cation transport GO:0015672 172 0.159
cation transmembrane transport GO:0098655 263 0.152
transmembrane transport GO:0055085 412 0.149
cation transport GO:0006812 382 0.131
ion transmembrane transport GO:0034220 365 0.126
secretion by cell GO:0032940 248 0.105
cation homeostasis GO:0055080 195 0.104
blood circulation GO:0008015 183 0.101
response to inorganic substance GO:0010035 377 0.099
positive regulation of secretion GO:0051047 140 0.099
cellular cation homeostasis GO:0030003 180 0.093
secretion GO:0046903 307 0.091
cytosolic calcium ion homeostasis GO:0051480 140 0.088
response to extracellular stimulus GO:0009991 380 0.087
regulation of multicellular organismal development GO:2000026 376 0.083
metal ion transport GO:0030001 289 0.082
cellular chemical homeostasis GO:0055082 247 0.081
brain development GO:0007420 247 0.080
response to external biotic stimulus GO:0043207 221 0.075
organic hydroxy compound metabolic process GO:1901615 115 0.074
regulation of ion transport GO:0043269 245 0.071
cellular homeostasis GO:0019725 252 0.069
head development GO:0060322 247 0.069
cellular amino acid metabolic process GO:0006520 107 0.065
heart contraction GO:0060047 57 0.065
cellular calcium ion homeostasis GO:0006874 160 0.064
macromolecular complex subunit organization GO:0043933 339 0.064
cellular ketone metabolic process GO:0042180 51 0.064
regulation of secretion GO:0051046 224 0.064
cellular ion homeostasis GO:0006873 184 0.063
response to alkaloid GO:0043279 132 0.058
response to oxygen levels GO:0070482 265 0.058
chemical homeostasis GO:0048878 292 0.058
reproduction GO:0000003 245 0.056
behavioral response to nicotine GO:0035095 2 0.056
cellular divalent inorganic cation homeostasis GO:0072503 162 0.055
cellular response to organic cyclic compound GO:0071407 202 0.053
response to decreased oxygen levels GO:0036293 237 0.053
regulation of neurogenesis GO:0050767 247 0.052
small molecule biosynthetic process GO:0044283 124 0.052
synaptic transmission GO:0007268 235 0.051
synaptic transmission glycinergic GO:0060012 2 0.050
positive regulation of cellular component movement GO:0051272 102 0.050
positive regulation of peptide secretion GO:0002793 52 0.049
nitrogen compound transport GO:0071705 229 0.048
protein heterooligomerization GO:0051291 89 0.048
ion homeostasis GO:0050801 212 0.048
organic anion transport GO:0015711 132 0.048
positive regulation of transport GO:0051050 245 0.047
organic acid biosynthetic process GO:0016053 83 0.045
protein complex assembly GO:0006461 263 0.045
central nervous system development GO:0007417 311 0.045
regulation of cell differentiation GO:0045595 320 0.044
regulation of cellular localization GO:0060341 263 0.044
inorganic cation transmembrane transport GO:0098662 202 0.044
aging GO:0007568 241 0.044
regulation of metal ion transport GO:0010959 118 0.043
adult locomotory behavior GO:0008344 4 0.042
response to oxidative stress GO:0006979 186 0.042
sodium ion transmembrane transport GO:0035725 67 0.042
anion transmembrane transport GO:0098656 77 0.042
regulation of secretion by cell GO:1903530 208 0.041
protein complex biogenesis GO:0070271 263 0.041
response to hypoxia GO:0001666 231 0.040
cellular response to histamine GO:0071420 3 0.040
calcium ion import GO:0070509 22 0.040
response to histamine GO:0034776 3 0.040
programmed cell death GO:0012501 392 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
vascular process in circulatory system GO:0003018 96 0.039
signal release GO:0023061 145 0.039
positive regulation of amine transport GO:0051954 26 0.038
growth GO:0040007 165 0.038
development of primary sexual characteristics GO:0045137 107 0.038
regulation of cellular component organization GO:0051128 368 0.038
inorganic ion transmembrane transport GO:0098660 229 0.038
protein complex subunit organization GO:0071822 302 0.037
calcium ion homeostasis GO:0055074 162 0.037
response to metal ion GO:0010038 253 0.037
oxoacid metabolic process GO:0043436 290 0.037
positive regulation of secretion by cell GO:1903532 128 0.036
action potential GO:0001508 54 0.036
single organism biosynthetic process GO:0044711 342 0.035
cell growth GO:0016049 104 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cellular response to hormone stimulus GO:0032870 247 0.035
regulation of blood circulation GO:1903522 110 0.035
regulation of nervous system development GO:0051960 264 0.035
locomotion GO:0040011 237 0.034
anion transport GO:0006820 178 0.033
metal ion homeostasis GO:0055065 186 0.033
response to increased oxygen levels GO:0036296 45 0.033
organic acid metabolic process GO:0006082 292 0.033
circulatory system development GO:0072359 134 0.033
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.033
cellular component movement GO:0006928 248 0.032
cellular response to peptide GO:1901653 133 0.032
hormone secretion GO:0046879 115 0.032
adult behavior GO:0030534 16 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
protein oligomerization GO:0051259 191 0.031
regulation of cell proliferation GO:0042127 359 0.031
regulation of blood vessel size GO:0050880 89 0.030
circulatory system process GO:0003013 183 0.030
response to carbohydrate GO:0009743 183 0.030
muscle system process GO:0003012 115 0.030
peptide transport GO:0015833 97 0.030
response to nutrient levels GO:0031667 370 0.030
sensory perception GO:0007600 101 0.030
intracellular signal transduction GO:0035556 314 0.030
negative regulation of transport GO:0051051 136 0.029
amine metabolic process GO:0009308 38 0.029
regulation of system process GO:0044057 208 0.029
regulation of response to stress GO:0080134 126 0.029
cellular amine metabolic process GO:0044106 38 0.029
response to ammonium ion GO:0060359 71 0.029
cellular response to stress GO:0033554 269 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
regulation of calcium ion transport GO:0051924 77 0.027
cell morphogenesis GO:0000902 142 0.027
lipid biosynthetic process GO:0008610 128 0.027
hormone transport GO:0009914 121 0.027
neurological system process GO:0050877 219 0.026
regulation of neuron differentiation GO:0045664 208 0.026
regulation of synaptic transmission GO:0050804 141 0.026
macromolecular complex assembly GO:0065003 273 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
lipid metabolic process GO:0006629 283 0.025
regulation of locomotion GO:0040012 148 0.025
organic substance catabolic process GO:1901575 316 0.025
positive regulation of signaling GO:0023056 270 0.025
cell adhesion GO:0007155 110 0.025
calcium ion transmembrane transport GO:0070588 70 0.025
regulation of anatomical structure size GO:0090066 135 0.024
reproductive process GO:0022414 372 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
amide transport GO:0042886 105 0.024
neuron projection development GO:0031175 273 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of peptide secretion GO:0002791 82 0.023
single organism reproductive process GO:0044702 297 0.023
peptide secretion GO:0002790 86 0.023
female sex differentiation GO:0046660 59 0.023
cell migration GO:0016477 197 0.023
cellular response to endogenous stimulus GO:0071495 377 0.022
striated muscle contraction GO:0006941 44 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
regulation of apoptotic process GO:0042981 335 0.022
regulation of peptide transport GO:0090087 87 0.022
positive regulation of developmental process GO:0051094 283 0.022
catabolic process GO:0009056 351 0.022
micturition GO:0060073 4 0.022
regulation of transmembrane transport GO:0034762 122 0.022
steroid biosynthetic process GO:0006694 48 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
regulation of hormone secretion GO:0046883 106 0.022
positive regulation of cell communication GO:0010647 271 0.021
organic acid transport GO:0015849 116 0.021
glucose homeostasis GO:0042593 75 0.021
regulation of organic acid transport GO:0032890 35 0.021
cell motility GO:0048870 202 0.021
regulation of neuron projection development GO:0010975 161 0.021
response to monosaccharide GO:0034284 159 0.020
positive regulation of ion transport GO:0043270 94 0.020
neuromuscular process GO:0050905 2 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
rhythmic process GO:0048511 156 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
positive regulation of cell development GO:0010720 176 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
cardiovascular system development GO:0072358 134 0.020
gonad development GO:0008406 104 0.020
intracellular transport GO:0046907 185 0.020
small molecule catabolic process GO:0044282 59 0.020
synaptic transmission glutamatergic GO:0035249 33 0.019
cell projection organization GO:0030030 302 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
spermatogenesis GO:0007283 99 0.019
regulation of anion transport GO:0044070 43 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of cell growth GO:0001558 85 0.018
dopamine secretion GO:0014046 15 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of amine transport GO:0051952 54 0.018
muscle cell migration GO:0014812 36 0.018
negative regulation of cell death GO:0060548 229 0.018
regulation of membrane potential GO:0042391 110 0.018
amino acid transport GO:0006865 70 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
regulation of smooth muscle contraction GO:0006940 29 0.017
positive regulation of peptide hormone secretion GO:0090277 50 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
positive regulation of signal transduction GO:0009967 175 0.017
cellular component biogenesis GO:0044085 368 0.017
divalent inorganic cation transport GO:0072511 134 0.017
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.017
neuron differentiation GO:0030182 368 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
phosphatidylinositol dephosphorylation GO:0046856 4 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
response to electrical stimulus GO:0051602 56 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
response to wounding GO:0009611 254 0.016
tissue development GO:0009888 252 0.016
reproductive structure development GO:0048608 128 0.016
positive regulation of cell death GO:0010942 184 0.016
regulation of rna metabolic process GO:0051252 391 0.016
regulation of heart contraction GO:0008016 48 0.016
gamete generation GO:0007276 124 0.016
cellular response to oxidative stress GO:0034599 76 0.016
response to cocaine GO:0042220 39 0.016
catecholamine secretion GO:0050432 33 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
negative regulation of collagen biosynthetic process GO:0032966 4 0.015
muscle contraction GO:0006936 88 0.015
regulation of hormone levels GO:0010817 187 0.015
potassium ion transmembrane transport GO:0071805 71 0.015
response to vitamin GO:0033273 131 0.015
regulation of tube size GO:0035150 89 0.015
neuron neuron synaptic transmission GO:0007270 60 0.015
response to hyperoxia GO:0055093 45 0.015
cellular component assembly GO:0022607 360 0.015
response to biotic stimulus GO:0009607 226 0.015
protein phosphorylation GO:0006468 345 0.015
regulation of growth GO:0040008 105 0.015
bone development GO:0060348 25 0.015
response to radiation GO:0009314 137 0.015
chemosensory behavior GO:0007635 2 0.015
regulation of smooth muscle cell migration GO:0014910 36 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of leukocyte degranulation GO:0043302 4 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.015
divalent metal ion transport GO:0070838 132 0.014
vesicle mediated transport GO:0016192 181 0.014
localization of cell GO:0051674 202 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
positive regulation of cell motility GO:2000147 97 0.014
saliva secretion GO:0046541 3 0.014
protein homooligomerization GO:0051260 91 0.014
circadian rhythm GO:0007623 88 0.014
response to hexose GO:0009746 144 0.014
positive regulation of locomotion GO:0040017 102 0.014
single organism catabolic process GO:0044712 283 0.014
negative regulation of peptide hormone secretion GO:0090278 30 0.014
response to nicotine GO:0035094 51 0.014
response to ethanol GO:0045471 162 0.014
interleukin 1 beta secretion GO:0050702 3 0.014
cellular response to fluid shear stress GO:0071498 4 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.013
regulation of mapk cascade GO:0043408 116 0.013
positive regulation of fat cell proliferation GO:0070346 1 0.013
defecation GO:0030421 1 0.013
negative regulation of secretion GO:0051048 82 0.013
glucagon secretion GO:0070091 5 0.013
vasoconstriction GO:0042310 54 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
male gamete generation GO:0048232 99 0.013
regulation of molecular function GO:0065009 398 0.013
regulation of cellular component movement GO:0051270 150 0.013
terpenoid metabolic process GO:0006721 37 0.013
exploration behavior GO:0035640 1 0.013
serotonin receptor signaling pathway GO:0007210 10 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
potassium ion homeostasis GO:0055075 2 0.013
limb morphogenesis GO:0035108 4 0.012
neuron fate commitment GO:0048663 4 0.012
apoptotic process GO:0006915 381 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
carboxylic acid transport GO:0046942 115 0.012
monoamine transport GO:0015844 43 0.012
limbic system development GO:0021761 38 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of immune system process GO:0002682 123 0.012
phenol containing compound metabolic process GO:0018958 30 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
response to toxic substance GO:0009636 133 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
female pregnancy GO:0007565 122 0.012
regulation of cell motility GO:2000145 131 0.012
regulation of response to external stimulus GO:0032101 106 0.012
cell type specific apoptotic process GO:0097285 134 0.012
response to tumor necrosis factor GO:0034612 56 0.012
regulation of blood pressure GO:0008217 83 0.012
cellular response to ketone GO:1901655 51 0.012
response to bacterium GO:0009617 200 0.012
response to purine containing compound GO:0014074 126 0.012
response to cytokine GO:0034097 215 0.011
renal system process GO:0003014 40 0.011
regulation of amino acid transport GO:0051955 25 0.011
response to mechanical stimulus GO:0009612 134 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
cellular response to drug GO:0035690 30 0.011
endocrine hormone secretion GO:0060986 21 0.011
positive regulation of organic acid transport GO:0032892 22 0.011
sexual reproduction GO:0019953 148 0.011
response to nutrient GO:0007584 248 0.011
rna metabolic process GO:0016070 406 0.011
nucleic acid templated transcription GO:0097659 379 0.011
rna biosynthetic process GO:0032774 380 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
neuron development GO:0048666 286 0.011
sodium ion transport GO:0006814 82 0.011
rho protein signal transduction GO:0007266 11 0.011
reproductive system development GO:0061458 128 0.011
regulation of cell projection organization GO:0031344 175 0.011
carbohydrate homeostasis GO:0033500 75 0.011
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.010
positive regulation of serotonin secretion GO:0014064 1 0.010
lipid localization GO:0010876 62 0.010
central nervous system neuron differentiation GO:0021953 17 0.010
regulation of cell development GO:0060284 263 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
response to cold GO:0009409 29 0.010
positive regulation of dopamine secretion GO:0033603 8 0.010
smooth muscle cell migration GO:0014909 36 0.010
telencephalon development GO:0021537 62 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
negative regulation of metabolic process GO:0009892 331 0.010
multicellular organismal catabolic process GO:0044243 2 0.010
monovalent inorganic cation homeostasis GO:0055067 36 0.010
regulation of cell migration GO:0030334 128 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
protein dephosphorylation GO:0006470 38 0.010
proteolysis GO:0006508 175 0.010
regulation of sodium ion transport GO:0002028 21 0.010
locomotory exploration behavior GO:0035641 1 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
sex differentiation GO:0007548 113 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
respiratory gaseous exchange GO:0007585 4 0.010

Grm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.017