Rattus norvegicus

53 known processes

Gucy1a2

guanylate cyclase 1, soluble, alpha 2

Gucy1a2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
jak stat cascade GO:0007259 26 0.231
cation transport GO:0006812 382 0.213
cellular component assembly GO:0022607 360 0.175
regulation of phosphorus metabolic process GO:0051174 349 0.172
Mouse
mapk cascade GO:0000165 140 0.149
biological adhesion GO:0022610 110 0.145
carbohydrate derivative metabolic process GO:1901135 346 0.143
homeostatic process GO:0042592 331 0.118
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.109
multi multicellular organism process GO:0044706 138 0.106
regulation of amine transport GO:0051952 54 0.105
cell adhesion GO:0007155 110 0.099
regulation of phosphate metabolic process GO:0019220 349 0.097
Mouse
positive regulation of ion transport GO:0043270 94 0.096
regulation of signal transduction GO:0009966 318 0.096
single organism biosynthetic process GO:0044711 342 0.094
reproductive process GO:0022414 372 0.091
regulation of phosphorylation GO:0042325 248 0.090
regulation of glutamate secretion GO:0014048 17 0.090
response to estradiol GO:0032355 164 0.089
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.085
intracellular signal transduction GO:0035556 314 0.085
Rat
rhythmic process GO:0048511 156 0.085
single organism behavior GO:0044708 130 0.084
nucleic acid templated transcription GO:0097659 379 0.081
regulation of cellular protein metabolic process GO:0032268 267 0.080
cellular component biogenesis GO:0044085 368 0.079
nucleobase containing small molecule metabolic process GO:0055086 316 0.075
positive regulation of transport GO:0051050 245 0.075
positive regulation of biosynthetic process GO:0009891 319 0.073
Mouse
response to radiation GO:0009314 137 0.073
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.072
regulation of rna biosynthetic process GO:2001141 381 0.071
cellular metal ion homeostasis GO:0006875 172 0.071
positive regulation of cellular biosynthetic process GO:0031328 295 0.070
Mouse
response to cytokine GO:0034097 215 0.068
neurotransmitter gated ion channel clustering GO:0072578 3 0.068
metal ion homeostasis GO:0055065 186 0.067
potassium ion transport GO:0006813 97 0.066
cytosolic calcium ion homeostasis GO:0051480 140 0.065
regulation of nucleic acid templated transcription GO:1903506 380 0.064
protein oligomerization GO:0051259 191 0.064
positive regulation of cell communication GO:0010647 271 0.064
reproduction GO:0000003 245 0.063
regulation of intracellular signal transduction GO:1902531 218 0.063
positive regulation of cell proliferation GO:0008284 249 0.063
regulation of secretion GO:0051046 224 0.062
multicellular organismal reproductive process GO:0048609 233 0.060
macromolecular complex subunit organization GO:0043933 339 0.059
protein localization GO:0008104 191 0.059
regulation of membrane potential GO:0042391 110 0.057
regulation of cell proliferation GO:0042127 359 0.057
cellular ion homeostasis GO:0006873 184 0.057
macromolecular complex assembly GO:0065003 273 0.056
macromolecule localization GO:0033036 252 0.055
metal ion transport GO:0030001 289 0.055
protein complex subunit organization GO:0071822 302 0.055
cellular chemical homeostasis GO:0055082 247 0.055
calcium ion homeostasis GO:0055074 162 0.055
carbohydrate metabolic process GO:0005975 130 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.053
ion homeostasis GO:0050801 212 0.052
negative regulation of gene expression GO:0010629 199 0.051
negative regulation of metabolic process GO:0009892 331 0.051
regulation of jak stat cascade GO:0046425 21 0.050
cellular catabolic process GO:0044248 295 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.049
multi organism reproductive process GO:0044703 262 0.048
positive regulation of phosphate metabolic process GO:0045937 262 0.048
Mouse
protein complex assembly GO:0006461 263 0.048
response to peptide hormone GO:0043434 278 0.046
response to estrogen GO:0043627 232 0.046
nucleoside phosphate biosynthetic process GO:1901293 102 0.045
regulation of apoptotic process GO:0042981 335 0.045
regulation of potassium ion transport GO:0043266 29 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
response to inorganic substance GO:0010035 377 0.042
cellular homeostasis GO:0019725 252 0.042
response to peptide GO:1901652 292 0.042
ribonucleotide metabolic process GO:0009259 231 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
Mouse
positive regulation of response to stimulus GO:0048584 285 0.041
positive regulation of developmental process GO:0051094 283 0.041
rna biosynthetic process GO:0032774 380 0.040
organic anion transport GO:0015711 132 0.040
apoptotic process GO:0006915 381 0.040
response to reactive oxygen species GO:0000302 120 0.040
regulation of cell differentiation GO:0045595 320 0.039
regulation of immune system process GO:0002682 123 0.039
regulation of ion transport GO:0043269 245 0.039
head development GO:0060322 247 0.039
catabolic process GO:0009056 351 0.039
chemical homeostasis GO:0048878 292 0.038
multicellular organism reproduction GO:0032504 233 0.038
organophosphate biosynthetic process GO:0090407 143 0.037
transmembrane transport GO:0055085 412 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of anion transport GO:0044070 43 0.037
anion transport GO:0006820 178 0.037
organophosphate metabolic process GO:0019637 370 0.037
regulation of organic acid transport GO:0032890 35 0.036
positive regulation of protein modification process GO:0031401 142 0.036
anterior posterior pattern specification GO:0009952 1 0.036
cell cell signaling GO:0007267 335 0.036
cellular cation homeostasis GO:0030003 180 0.035
development of primary female sexual characteristics GO:0046545 56 0.034
cellular calcium ion homeostasis GO:0006874 160 0.034
female pregnancy GO:0007565 122 0.034
regulation of cellular component organization GO:0051128 368 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
protein phosphorylation GO:0006468 345 0.033
positive regulation of signal transduction GO:0009967 175 0.033
positive regulation of saliva secretion GO:0046878 3 0.033
regulation of secretion by cell GO:1903530 208 0.033
transcription dna templated GO:0006351 377 0.033
locomotor rhythm GO:0045475 1 0.033
growth GO:0040007 165 0.033
secretion by cell GO:0032940 248 0.033
regulation of postsynaptic membrane potential GO:0060078 25 0.032
synapse organization GO:0050808 46 0.032
response to mechanical stimulus GO:0009612 134 0.032
positive regulation of phosphorylation GO:0042327 177 0.032
response to hypoxia GO:0001666 231 0.031
regulation of amino acid transport GO:0051955 25 0.031
negative regulation of transport GO:0051051 136 0.031
positive regulation of signaling GO:0023056 270 0.031
organic acid metabolic process GO:0006082 292 0.031
regulation of cellular localization GO:0060341 263 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
amine transport GO:0015837 57 0.029
circulatory system development GO:0072359 134 0.029
receptor localization to synapse GO:0097120 2 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
Fly
nucleotide metabolic process GO:0009117 279 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
cellular amine metabolic process GO:0044106 38 0.029
cellular amino acid metabolic process GO:0006520 107 0.028
circadian rhythm GO:0007623 88 0.028
rna metabolic process GO:0016070 406 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
divalent inorganic cation homeostasis GO:0072507 165 0.027
organic substance catabolic process GO:1901575 316 0.027
regulation of response to stress GO:0080134 126 0.027
central nervous system development GO:0007417 311 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
Mouse
cyclic nucleotide biosynthetic process GO:0009190 63 0.027
learning GO:0007612 33 0.027
negative regulation of molecular function GO:0044092 133 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
purine containing compound metabolic process GO:0072521 253 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
positive regulation of nervous system development GO:0051962 178 0.026
synaptic transmission GO:0007268 235 0.026
camp metabolic process GO:0046058 63 0.026
regulation of synaptic transmission GO:0050804 141 0.026
protein complex biogenesis GO:0070271 263 0.026
cellular response to stress GO:0033554 269 0.026
eating behavior GO:0042755 21 0.025
cardiovascular system development GO:0072358 134 0.025
synaptic transmission gabaergic GO:0051932 22 0.024
response to decreased oxygen levels GO:0036293 237 0.024
cellular protein localization GO:0034613 122 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
cellular response to oxidative stress GO:0034599 76 0.024
regulation of protein metabolic process GO:0051246 289 0.024
purine containing compound biosynthetic process GO:0072522 85 0.024
positive regulation of protein kinase activity GO:0045860 73 0.024
embryonic pattern specification GO:0009880 1 0.024
response to ethanol GO:0045471 162 0.024
response to nutrient levels GO:0031667 370 0.024
regulation of transcription dna templated GO:0006355 374 0.023
saliva secretion GO:0046541 3 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
cell motility GO:0048870 202 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
mononuclear cell proliferation GO:0032943 29 0.023
positive regulation of kinase activity GO:0033674 77 0.023
regulation of protein phosphorylation GO:0001932 183 0.022
regulation of molecular function GO:0065009 398 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
divalent inorganic cation transport GO:0072511 134 0.022
neuron development GO:0048666 286 0.022
behavior GO:0007610 205 0.022
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
Mouse
muscle cell proliferation GO:0033002 84 0.022
localization of cell GO:0051674 202 0.022
cyclic nucleotide metabolic process GO:0009187 80 0.022
regulation of mapk cascade GO:0043408 116 0.022
amine metabolic process GO:0009308 38 0.022
response to toxic substance GO:0009636 133 0.021
Rat
response to alkaloid GO:0043279 132 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
membrane organization GO:0061024 94 0.021
synaptic transmission glutamatergic GO:0035249 33 0.021
immune system process GO:0002376 204 0.021
response to light stimulus GO:0009416 52 0.021
Fly
regulation of nervous system development GO:0051960 264 0.021
negative regulation of protein processing GO:0010955 47 0.021
regulation of neurogenesis GO:0050767 247 0.021
brain development GO:0007420 247 0.020
purine nucleoside monophosphate catabolic process GO:0009128 55 0.020
regulation of rna metabolic process GO:0051252 391 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cell fate commitment involved in pattern specification GO:0060581 2 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
positive regulation of synaptic transmission GO:0050806 62 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
positive regulation of gene expression GO:0010628 244 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
ovulation cycle GO:0042698 67 0.020
lymphocyte proliferation GO:0046651 29 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of cell development GO:0010720 176 0.020
cellular ketone metabolic process GO:0042180 51 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of cell development GO:0060284 263 0.020
positive regulation of potassium ion transport GO:0043268 13 0.020
nitrogen compound transport GO:0071705 229 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
negative regulation of cell death GO:0060548 229 0.019
positive regulation of lymphocyte proliferation GO:0050671 20 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of transmembrane transport GO:0034762 122 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of amine transport GO:0051953 24 0.018
regeneration GO:0031099 163 0.018
regulation of growth GO:0040008 105 0.018
neurological system process GO:0050877 219 0.018
gamete generation GO:0007276 124 0.018
oxoacid metabolic process GO:0043436 290 0.018
locomotory behavior GO:0007626 15 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of cell death GO:0010942 184 0.018
sexual reproduction GO:0019953 148 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
cell activation GO:0001775 97 0.017
regulation of homeostatic process GO:0032844 101 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
nucleoside monophosphate metabolic process GO:0009123 93 0.017
neuron differentiation GO:0030182 368 0.017
negative regulation of blood vessel morphogenesis GO:2000181 10 0.017
neuron neuron synaptic transmission GO:0007270 60 0.017
regulation of system process GO:0044057 208 0.017
regulation of protein modification process GO:0031399 194 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.017
programmed cell death GO:0012501 392 0.017
regulation of programmed cell death GO:0043067 341 0.017
asymmetric protein localization GO:0008105 2 0.017
rhythmic behavior GO:0007622 24 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
response to extracellular stimulus GO:0009991 380 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.017
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.017
negative regulation of cell communication GO:0010648 158 0.016
response to wounding GO:0009611 254 0.016
developmental process involved in reproduction GO:0003006 159 0.016
dopamine transport GO:0015872 18 0.016
embryonic axis specification GO:0000578 1 0.016
neuronal action potential GO:0019228 35 0.016
regulation of cell migration GO:0030334 128 0.016
negative regulation of protein maturation GO:1903318 47 0.016
vasculature development GO:0001944 70 0.016
steroid metabolic process GO:0008202 73 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.016
Mouse
heterocycle catabolic process GO:0046700 167 0.016
cellular macromolecule localization GO:0070727 122 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
regulation of transmembrane transporter activity GO:0022898 49 0.016
action potential GO:0001508 54 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
regulation of cell activation GO:0050865 50 0.016
response to calcium ion GO:0051592 59 0.016
regulation of transporter activity GO:0032409 50 0.016
muscle cell differentiation GO:0042692 52 0.016
regulation of metal ion transport GO:0010959 118 0.016
camp biosynthetic process GO:0006171 47 0.015
response to ketone GO:1901654 182 0.015
regulation of glutamate receptor signaling pathway GO:1900449 17 0.015
carboxylic acid transport GO:0046942 115 0.015
muscle tissue development GO:0060537 58 0.015
positive regulation of amine transport GO:0051954 26 0.015
monoamine transport GO:0015844 43 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
response to vitamin GO:0033273 131 0.015
tissue development GO:0009888 252 0.015
transmission of nerve impulse GO:0019226 42 0.015
response to temperature stimulus GO:0009266 94 0.015
negative regulation of secretion GO:0051048 82 0.015
epithelium development GO:0060429 96 0.015
striated muscle tissue development GO:0014706 58 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
regulation of blood circulation GO:1903522 110 0.015
sensory perception of pain GO:0019233 73 0.015
regulation of protein maturation GO:1903317 50 0.014
receptor mediated endocytosis GO:0006898 42 0.014
blood vessel morphogenesis GO:0048514 58 0.014
vascular process in circulatory system GO:0003018 96 0.014
feeding behavior GO:0007631 53 0.014
negative regulation of receptor internalization GO:0002091 2 0.014
neuronal ion channel clustering GO:0045161 3 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of response to external stimulus GO:0032101 106 0.014
secretion GO:0046903 307 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of secretion GO:0051047 140 0.014
maintenance of location GO:0051235 17 0.014
blood circulation GO:0008015 183 0.014
aging GO:0007568 241 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
ossification GO:0001503 70 0.014
regulation of hydrolase activity GO:0051336 143 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
positive regulation of growth GO:0045927 55 0.014
ras protein signal transduction GO:0007265 29 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
single organism reproductive process GO:0044702 297 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
response to lipopolysaccharide GO:0032496 191 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
negative regulation of immune system process GO:0002683 39 0.013
calcium ion transport GO:0006816 131 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
negative regulation of developmental process GO:0051093 125 0.013
neuron projection development GO:0031175 273 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
response to amine GO:0014075 46 0.013
multicellular organismal signaling GO:0035637 44 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
positive regulation of blood circulation GO:1903524 65 0.013
regulation of defense response GO:0031347 68 0.013
epithelial cell proliferation GO:0050673 54 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cerebellar granule cell precursor proliferation GO:0021930 1 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
regulation of synaptic transmission gabaergic GO:0032228 17 0.012
developmental growth GO:0048589 100 0.012
regulation of kinase activity GO:0043549 117 0.012
peptidyl amino acid modification GO:0018193 126 0.012
purine containing compound catabolic process GO:0072523 138 0.012
oxidation reduction process GO:0055114 304 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
sex differentiation GO:0007548 113 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
male mating behavior GO:0060179 3 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
negative regulation of proteolysis GO:0045861 41 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
response to oxidative stress GO:0006979 186 0.012
ion transmembrane transport GO:0034220 365 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of vasculature development GO:1901342 44 0.012
cognition GO:0050890 92 0.011
response to insulin GO:0032868 133 0.011
cellular component morphogenesis GO:0032989 155 0.011
salivary gland development GO:0007431 3 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
organ regeneration GO:0031100 101 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of catecholamine secretion GO:0050433 32 0.011
cerebral cortex development GO:0021987 18 0.011
cell projection organization GO:0030030 302 0.011
nucleoside metabolic process GO:0009116 179 0.011
regulation of proteolysis GO:0030162 66 0.011
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.011
glutamate receptor signaling pathway GO:0007215 43 0.011
synapse assembly GO:0007416 29 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
reproductive structure development GO:0048608 128 0.011
tube development GO:0035295 89 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
organic acid transport GO:0015849 116 0.011
regulation of receptor activity GO:0010469 29 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
organic hydroxy compound transport GO:0015850 77 0.011
negative regulation of signaling GO:0023057 157 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of hormone levels GO:0010817 187 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
hormone mediated signaling pathway GO:0009755 23 0.010
defense response GO:0006952 194 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
endocytosis GO:0006897 84 0.010
nucleotide catabolic process GO:0009166 139 0.010
regulation of ion homeostasis GO:2000021 63 0.010
cation transmembrane transport GO:0098655 263 0.010
negative regulation of synaptic transmission GO:0050805 29 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
negative regulation of peptidase activity GO:0010466 38 0.010
organelle localization GO:0051640 55 0.010
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.010

Gucy1a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015