Rattus norvegicus

0 known processes

Gucy1b2

guanylate cyclase 1, soluble, beta 2

(Aliases: Gucy1b2b,Gucy1b2a,SGC)

Gucy1b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.183
transmembrane transport GO:0055085 412 0.165
regulation of ion transport GO:0043269 245 0.146
head development GO:0060322 247 0.138
regulation of apoptotic process GO:0042981 335 0.134
response to metal ion GO:0010038 253 0.127
regulation of cellular component organization GO:0051128 368 0.123
glycerolipid metabolic process GO:0046486 67 0.113
regulation of metal ion transport GO:0010959 118 0.110
organic hydroxy compound transport GO:0015850 77 0.090
response to biotic stimulus GO:0009607 226 0.086
negative regulation of serine type peptidase activity GO:1902572 1 0.086
response to glucocorticoid GO:0051384 223 0.085
macromolecule localization GO:0033036 252 0.085
cellular chemical homeostasis GO:0055082 247 0.084
response to corticosteroid GO:0031960 235 0.083
response to acid chemical GO:0001101 222 0.079
macromolecular complex assembly GO:0065003 273 0.073
positive regulation of multicellular organismal process GO:0051240 387 0.070
regulation of catalytic activity GO:0050790 304 0.067
cation transmembrane transport GO:0098655 263 0.067
nucleobase containing small molecule metabolic process GO:0055086 316 0.066
Rat
response to estradiol GO:0032355 164 0.064
regulation of multicellular organismal development GO:2000026 376 0.064
immune response GO:0006955 104 0.063
response to inorganic substance GO:0010035 377 0.063
protein complex biogenesis GO:0070271 263 0.063
response to oxygen levels GO:0070482 265 0.063
Worm
metal ion homeostasis GO:0055065 186 0.061
ion transmembrane transport GO:0034220 365 0.061
protein complex assembly GO:0006461 263 0.059
establishment of protein localization GO:0045184 141 0.059
neuron differentiation GO:0030182 368 0.057
protein localization GO:0008104 191 0.057
regulation of cell projection organization GO:0031344 175 0.054
oxoacid metabolic process GO:0043436 290 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
synaptic transmission GO:0007268 235 0.051
monovalent inorganic cation transport GO:0015672 172 0.051
negative regulation of serine type endopeptidase activity GO:1900004 1 0.051
tripeptide transport GO:0042939 2 0.051
response to methanol GO:0033986 1 0.051
positive regulation of signaling GO:0023056 270 0.051
g protein coupled receptor signaling pathway GO:0007186 242 0.050
nucleotide metabolic process GO:0009117 279 0.049
Rat
programmed cell death GO:0012501 392 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.049
Rat
cellular sodium ion homeostasis GO:0006883 4 0.049
divalent inorganic cation transport GO:0072511 134 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.048
regulation of signal transduction GO:0009966 318 0.048
response to toxic substance GO:0009636 133 0.048
Rat
divalent metal ion transport GO:0070838 132 0.048
protein oligomerization GO:0051259 191 0.048
immune system process GO:0002376 204 0.048
response to ketone GO:1901654 182 0.048
positive regulation of hydrolase activity GO:0051345 86 0.048
cellular metal ion homeostasis GO:0006875 172 0.048
single organism carbohydrate metabolic process GO:0044723 118 0.047
cellular lipid metabolic process GO:0044255 208 0.047
anatomical structure morphogenesis GO:0009653 298 0.046
renin angiotensin regulation of aldosterone production GO:0002018 3 0.046
positive regulation of catalytic activity GO:0043085 184 0.046
response to lipopolysaccharide GO:0032496 191 0.046
cell migration GO:0016477 197 0.046
cellular component assembly GO:0022607 360 0.044
negative regulation of developmental process GO:0051093 125 0.044
organonitrogen compound biosynthetic process GO:1901566 167 0.044
Rat
regulation of molecular function GO:0065009 398 0.044
neuron development GO:0048666 286 0.043
regulation of protein metabolic process GO:0051246 289 0.043
response to oxidative stress GO:0006979 186 0.043
regulation of calcium ion transport GO:0051924 77 0.043
transmission of nerve impulse GO:0019226 42 0.042
blood circulation GO:0008015 183 0.042
ion homeostasis GO:0050801 212 0.042
positive regulation of cell development GO:0010720 176 0.041
apoptotic process GO:0006915 381 0.041
response to extracellular stimulus GO:0009991 380 0.041
homeostatic process GO:0042592 331 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.041
metal ion transport GO:0030001 289 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
positive regulation of cellular component organization GO:0051130 200 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
organic acid metabolic process GO:0006082 292 0.040
positive regulation of cell projection organization GO:0031346 111 0.039
cellular response to stress GO:0033554 269 0.039
regulation of hydrolase activity GO:0051336 143 0.038
regulation of nervous system development GO:0051960 264 0.038
negative regulation of metabolic process GO:0009892 331 0.038
organic anion transport GO:0015711 132 0.038
circulatory system process GO:0003013 183 0.038
cell motility GO:0048870 202 0.038
positive regulation of cell differentiation GO:0045597 217 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of neuron projection development GO:0010975 161 0.037
cellular ion homeostasis GO:0006873 184 0.037
amine metabolic process GO:0009308 38 0.037
response to nutrient levels GO:0031667 370 0.037
cell cell signaling GO:0007267 335 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
intracellular signal transduction GO:0035556 314 0.036
Rat
positive regulation of transport GO:0051050 245 0.036
cation homeostasis GO:0055080 195 0.036
response to nutrient GO:0007584 248 0.036
neuron projection development GO:0031175 273 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
oxidation reduction process GO:0055114 304 0.035
monocarboxylic acid metabolic process GO:0032787 152 0.034
negative regulation of ion transport GO:0043271 51 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
cell projection organization GO:0030030 302 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of cell proliferation GO:0042127 359 0.034
negative regulation of gene expression GO:0010629 199 0.033
small molecule biosynthetic process GO:0044283 124 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
cellular amine metabolic process GO:0044106 38 0.032
protein complex subunit organization GO:0071822 302 0.032
organophosphate metabolic process GO:0019637 370 0.032
Rat
regulation of cell differentiation GO:0045595 320 0.032
positive regulation of neuron differentiation GO:0045666 126 0.032
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
regulation of synaptic transmission GO:0050804 141 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
Rat
intracellular transport GO:0046907 185 0.031
cellular cation homeostasis GO:0030003 180 0.031
response to wounding GO:0009611 254 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
response to estrogen GO:0043627 232 0.030
response to external biotic stimulus GO:0043207 221 0.030
tonic smooth muscle contraction GO:0014820 4 0.030
aging GO:0007568 241 0.030
regulation of catecholamine secretion GO:0050433 32 0.029
regulation of cellular localization GO:0060341 263 0.029
muscle system process GO:0003012 115 0.029
purine containing compound metabolic process GO:0072521 253 0.029
Rat
response to vitamin b6 GO:0034516 1 0.029
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.028
protein heterooligomerization GO:0051291 89 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
Rat
lipid transport GO:0006869 61 0.028
catenin import into nucleus GO:0035411 1 0.028
ras protein signal transduction GO:0007265 29 0.028
brain development GO:0007420 247 0.028
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.028
cellular component biogenesis GO:0044085 368 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
catabolic process GO:0009056 351 0.028
response to triglyceride GO:0034014 3 0.028
regulation of immune system process GO:0002682 123 0.028
smooth muscle contraction GO:0006939 37 0.027
growth GO:0040007 165 0.027
positive regulation of serotonin secretion GO:0014064 1 0.027
positive regulation of developmental process GO:0051094 283 0.027
central nervous system development GO:0007417 311 0.026
organ regeneration GO:0031100 101 0.026
lipid localization GO:0010876 62 0.026
response to reactive oxygen species GO:0000302 120 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.025
positive regulation of molecular function GO:0044093 230 0.025
calcium ion transport GO:0006816 131 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of homeostatic process GO:0032844 101 0.025
b cell differentiation GO:0030183 2 0.025
regulation of blood pressure GO:0008217 83 0.024
response to bacterium GO:0009617 200 0.024
defense response GO:0006952 194 0.024
positive regulation of secretion GO:0051047 140 0.024
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.024
regulation of neurogenesis GO:0050767 247 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
small gtpase mediated signal transduction GO:0007264 36 0.023
glutathione transport GO:0034635 2 0.023
lipid metabolic process GO:0006629 283 0.023
developmental growth GO:0048589 100 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
response to mineralocorticoid GO:0051385 49 0.022
response to ethanol GO:0045471 162 0.022
response to molecule of fungal origin GO:0002238 3 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
negative regulation of cell differentiation GO:0045596 99 0.022
neuron neuron synaptic transmission GO:0007270 60 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of neuron differentiation GO:0045664 208 0.022
regulation of muscle system process GO:0090257 79 0.022
reactive nitrogen species metabolic process GO:2001057 1 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
striated muscle tissue development GO:0014706 58 0.022
cellular homeostasis GO:0019725 252 0.022
positive regulation of signal transduction GO:0009967 175 0.022
response to corticosterone GO:0051412 40 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
Rat
regulation of phosphate metabolic process GO:0019220 349 0.021
positive regulation of homeostatic process GO:0032846 49 0.021
multicellular organism growth GO:0035264 1 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
negative regulation of molecular function GO:0044092 133 0.021
regulation of blood circulation GO:1903522 110 0.021
regeneration GO:0031099 163 0.021
chemotaxis GO:0006935 66 0.021
rna biosynthetic process GO:0032774 380 0.021
oligopeptide transport GO:0006857 4 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
response to chromate GO:0046687 3 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to carbohydrate GO:0009743 183 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
immune system development GO:0002520 41 0.020
localization of cell GO:0051674 202 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
negative regulation of catalytic activity GO:0043086 103 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
Rat
multicellular organismal signaling GO:0035637 44 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.019
neurological system process GO:0050877 219 0.019
protein transport GO:0015031 132 0.019
cellular response to lipid GO:0071396 201 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.019
organic substance catabolic process GO:1901575 316 0.019
multi multicellular organism process GO:0044706 138 0.019
response to food GO:0032094 27 0.019
female pregnancy GO:0007565 122 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to vitamin GO:0033273 131 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
nucleocytoplasmic transport GO:0006913 48 0.019
tissue development GO:0009888 252 0.019
organic hydroxy compound biosynthetic process GO:1901617 51 0.019
negative regulation of vasculature development GO:1901343 11 0.018
regulation of extracellular matrix constituent secretion GO:0003330 2 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.018
regulation of cell growth GO:0001558 85 0.018
anion transport GO:0006820 178 0.018
cellular response to external stimulus GO:0071496 118 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
monoamine transport GO:0015844 43 0.018
regulation of growth GO:0040008 105 0.018
regulation of serine type peptidase activity GO:1902571 1 0.018
positive regulation of camp biosynthetic process GO:0030819 28 0.018
cellular component movement GO:0006928 248 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
Rat
respiratory system process GO:0003016 3 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
Rat
reproductive process GO:0022414 372 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cell growth GO:0016049 104 0.017
organelle organization GO:0006996 266 0.017
response to peptide GO:1901652 292 0.017
positive regulation of ion transport GO:0043270 94 0.017
cellular catabolic process GO:0044248 295 0.017
negative regulation of cell death GO:0060548 229 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
chemical homeostasis GO:0048878 292 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
protein targeting GO:0006605 61 0.016
temperature homeostasis GO:0001659 17 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
muscle tissue development GO:0060537 58 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of neurological system process GO:0031644 43 0.015
regulation of transmembrane transport GO:0034762 122 0.015
sodium ion transport GO:0006814 82 0.015
locomotion GO:0040011 237 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
nucleic acid templated transcription GO:0097659 379 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of signaling GO:0023057 157 0.015
organic acid transport GO:0015849 116 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
Rat
leukocyte differentiation GO:0002521 30 0.015
transcription dna templated GO:0006351 377 0.015
intracellular protein transport GO:0006886 79 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
brain renin angiotensin system GO:0002035 3 0.014
alcohol metabolic process GO:0006066 77 0.014
organic acid biosynthetic process GO:0016053 83 0.014
organophosphate catabolic process GO:0046434 148 0.014
artery smooth muscle contraction GO:0014824 4 0.014
inflammatory response GO:0006954 150 0.014
secretion GO:0046903 307 0.014
cytoplasmic transport GO:0016482 115 0.014
proteolysis GO:0006508 175 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cellular macromolecule localization GO:0070727 122 0.014
membrane organization GO:0061024 94 0.014
cellular protein localization GO:0034613 122 0.014
secretion by cell GO:0032940 248 0.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
monocarboxylic acid transport GO:0015718 52 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
single organism catabolic process GO:0044712 283 0.013
trichloroethylene metabolic process GO:0018979 1 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
neutral lipid metabolic process GO:0006638 21 0.013
coenzyme metabolic process GO:0006732 86 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of fibroblast proliferation GO:0048146 15 0.013
regulation of anatomical structure size GO:0090066 135 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
regulation of phosphorylation GO:0042325 248 0.013
protein homooligomerization GO:0051260 91 0.013
cellular response to oxidative stress GO:0034599 76 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of innate immune response GO:0045824 4 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of membrane potential GO:0042391 110 0.012
multi organism reproductive process GO:0044703 262 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of peptide transport GO:0090087 87 0.012
response to hypoxia GO:0001666 231 0.012
reproduction GO:0000003 245 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of blood vessel morphogenesis GO:2000181 10 0.012
single organism biosynthetic process GO:0044711 342 0.012
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cellular ketone metabolic process GO:0042180 51 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
muscle cell proliferation GO:0033002 84 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.011
lipid biosynthetic process GO:0008610 128 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
fatty acid metabolic process GO:0006631 99 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
vasculature development GO:0001944 70 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
lipid storage GO:0019915 1 0.011
camp metabolic process GO:0046058 63 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
neuronal action potential GO:0019228 35 0.011
single organism nuclear import GO:1902593 35 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
Rat
regulation of secretion GO:0051046 224 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of transcription dna templated GO:0006355 374 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
biological adhesion GO:0022610 110 0.011
forebrain development GO:0030900 98 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
fatty acid transport GO:0015908 25 0.011
fertilization GO:0009566 3 0.011
positive regulation of gene expression GO:0010628 244 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to testosterone GO:0033574 55 0.011
response to monosaccharide GO:0034284 159 0.011
response to glucose GO:0009749 136 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
rho protein signal transduction GO:0007266 11 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of leukocyte mediated immunity GO:0002703 19 0.010
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
establishment of protein localization to organelle GO:0072594 44 0.010
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
extracellular matrix constituent secretion GO:0070278 4 0.010
response to peptide hormone GO:0043434 278 0.010
positive regulation of protein modification process GO:0031401 142 0.010

Gucy1b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
cancer DOID:162 0 0.016
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011