Rattus norvegicus

0 known processes

Gucy1b2

guanylate cyclase 1, soluble, beta 2

(Aliases: Gucy1b2b,Gucy1b2a,SGC)

Gucy1b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.183
transmembrane transport GO:0055085 412 0.165
regulation of ion transport GO:0043269 245 0.146
head development GO:0060322 247 0.138
regulation of apoptotic process GO:0042981 335 0.134
response to metal ion GO:0010038 253 0.127
regulation of cellular component organization GO:0051128 368 0.123
glycerolipid metabolic process GO:0046486 67 0.113
regulation of metal ion transport GO:0010959 118 0.110
organic hydroxy compound transport GO:0015850 77 0.090
response to biotic stimulus GO:0009607 226 0.086
negative regulation of serine type peptidase activity GO:1902572 1 0.086
response to glucocorticoid GO:0051384 223 0.085
macromolecule localization GO:0033036 252 0.085
cellular chemical homeostasis GO:0055082 247 0.084
response to corticosteroid GO:0031960 235 0.083
response to acid chemical GO:0001101 222 0.079
macromolecular complex assembly GO:0065003 273 0.073
positive regulation of multicellular organismal process GO:0051240 387 0.070
regulation of catalytic activity GO:0050790 304 0.067
cation transmembrane transport GO:0098655 263 0.067
nucleobase containing small molecule metabolic process GO:0055086 316 0.066
Rat
response to estradiol GO:0032355 164 0.064
regulation of multicellular organismal development GO:2000026 376 0.064
immune response GO:0006955 104 0.063
response to inorganic substance GO:0010035 377 0.063
protein complex biogenesis GO:0070271 263 0.063
response to oxygen levels GO:0070482 265 0.063
Worm
metal ion homeostasis GO:0055065 186 0.061
ion transmembrane transport GO:0034220 365 0.061
protein complex assembly GO:0006461 263 0.059
establishment of protein localization GO:0045184 141 0.059
neuron differentiation GO:0030182 368 0.057
protein localization GO:0008104 191 0.057
regulation of cell projection organization GO:0031344 175 0.054
oxoacid metabolic process GO:0043436 290 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
synaptic transmission GO:0007268 235 0.051
monovalent inorganic cation transport GO:0015672 172 0.051
negative regulation of serine type endopeptidase activity GO:1900004 1 0.051
tripeptide transport GO:0042939 2 0.051
response to methanol GO:0033986 1 0.051
positive regulation of signaling GO:0023056 270 0.051
g protein coupled receptor signaling pathway GO:0007186 242 0.050
nucleotide metabolic process GO:0009117 279 0.049
Rat
programmed cell death GO:0012501 392 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.049
Rat
cellular sodium ion homeostasis GO:0006883 4 0.049
divalent inorganic cation transport GO:0072511 134 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.048
regulation of signal transduction GO:0009966 318 0.048
response to toxic substance GO:0009636 133 0.048
Rat
divalent metal ion transport GO:0070838 132 0.048
protein oligomerization GO:0051259 191 0.048
immune system process GO:0002376 204 0.048
response to ketone GO:1901654 182 0.048
positive regulation of hydrolase activity GO:0051345 86 0.048
cellular metal ion homeostasis GO:0006875 172 0.048
single organism carbohydrate metabolic process GO:0044723 118 0.047
cellular lipid metabolic process GO:0044255 208 0.047
anatomical structure morphogenesis GO:0009653 298 0.046
renin angiotensin regulation of aldosterone production GO:0002018 3 0.046
positive regulation of catalytic activity GO:0043085 184 0.046
response to lipopolysaccharide GO:0032496 191 0.046
cell migration GO:0016477 197 0.046
cellular component assembly GO:0022607 360 0.044
negative regulation of developmental process GO:0051093 125 0.044
organonitrogen compound biosynthetic process GO:1901566 167 0.044
Rat
regulation of molecular function GO:0065009 398 0.044
neuron development GO:0048666 286 0.043
regulation of protein metabolic process GO:0051246 289 0.043
response to oxidative stress GO:0006979 186 0.043
regulation of calcium ion transport GO:0051924 77 0.043
transmission of nerve impulse GO:0019226 42 0.042
blood circulation GO:0008015 183 0.042
ion homeostasis GO:0050801 212 0.042
positive regulation of cell development GO:0010720 176 0.041
apoptotic process GO:0006915 381 0.041
response to extracellular stimulus GO:0009991 380 0.041
homeostatic process GO:0042592 331 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.041
metal ion transport GO:0030001 289 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
positive regulation of cellular component organization GO:0051130 200 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
organic acid metabolic process GO:0006082 292 0.040
positive regulation of cell projection organization GO:0031346 111 0.039
cellular response to stress GO:0033554 269 0.039
regulation of hydrolase activity GO:0051336 143 0.038
regulation of nervous system development GO:0051960 264 0.038
negative regulation of metabolic process GO:0009892 331 0.038
organic anion transport GO:0015711 132 0.038
circulatory system process GO:0003013 183 0.038
cell motility GO:0048870 202 0.038
positive regulation of cell differentiation GO:0045597 217 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of neuron projection development GO:0010975 161 0.037
cellular ion homeostasis GO:0006873 184 0.037
amine metabolic process GO:0009308 38 0.037
response to nutrient levels GO:0031667 370 0.037
cell cell signaling GO:0007267 335 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
intracellular signal transduction GO:0035556 314 0.036
Rat
positive regulation of transport GO:0051050 245 0.036
cation homeostasis GO:0055080 195 0.036
response to nutrient GO:0007584 248 0.036
neuron projection development GO:0031175 273 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
oxidation reduction process GO:0055114 304 0.035
monocarboxylic acid metabolic process GO:0032787 152 0.034
negative regulation of ion transport GO:0043271 51 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
cell projection organization GO:0030030 302 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of cell proliferation GO:0042127 359 0.034
negative regulation of gene expression GO:0010629 199 0.033
small molecule biosynthetic process GO:0044283 124 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
cellular amine metabolic process GO:0044106 38 0.032
protein complex subunit organization GO:0071822 302 0.032
organophosphate metabolic process GO:0019637 370 0.032
Rat
regulation of cell differentiation GO:0045595 320 0.032
positive regulation of neuron differentiation GO:0045666 126 0.032
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
regulation of synaptic transmission GO:0050804 141 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
Rat
intracellular transport GO:0046907 185 0.031
cellular cation homeostasis GO:0030003 180 0.031
response to wounding GO:0009611 254 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
response to estrogen GO:0043627 232 0.030
response to external biotic stimulus GO:0043207 221 0.030
tonic smooth muscle contraction GO:0014820 4 0.030
aging GO:0007568 241 0.030
regulation of catecholamine secretion GO:0050433 32 0.029
regulation of cellular localization GO:0060341 263 0.029
muscle system process GO:0003012 115 0.029
purine containing compound metabolic process GO:0072521 253 0.029
Rat
response to vitamin b6 GO:0034516 1 0.029
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.028
protein heterooligomerization GO:0051291 89 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
Rat
lipid transport GO:0006869 61 0.028
catenin import into nucleus GO:0035411 1 0.028
ras protein signal transduction GO:0007265 29 0.028
brain development GO:0007420 247 0.028
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.028
cellular component biogenesis GO:0044085 368 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
catabolic process GO:0009056 351 0.028
response to triglyceride GO:0034014 3 0.028
regulation of immune system process GO:0002682 123 0.028
smooth muscle contraction GO:0006939 37 0.027
growth GO:0040007 165 0.027
positive regulation of serotonin secretion GO:0014064 1 0.027
positive regulation of developmental process GO:0051094 283 0.027
central nervous system development GO:0007417 311 0.026
organ regeneration GO:0031100 101 0.026
lipid localization GO:0010876 62 0.026
response to reactive oxygen species GO:0000302 120 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.025
positive regulation of molecular function GO:0044093 230 0.025
calcium ion transport GO:0006816 131 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of homeostatic process GO:0032844 101 0.025
b cell differentiation GO:0030183 2 0.025
regulation of blood pressure GO:0008217 83 0.024
response to bacterium GO:0009617 200 0.024
defense response GO:0006952 194 0.024
positive regulation of secretion GO:0051047 140 0.024
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.024
regulation of neurogenesis GO:0050767 247 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
small gtpase mediated signal transduction GO:0007264 36 0.023
glutathione transport GO:0034635 2 0.023
lipid metabolic process GO:0006629 283 0.023
developmental growth GO:0048589 100 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
response to mineralocorticoid GO:0051385 49 0.022
response to ethanol GO:0045471 162 0.022
response to molecule of fungal origin GO:0002238 3 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
negative regulation of cell differentiation GO:0045596 99 0.022
neuron neuron synaptic transmission GO:0007270 60 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of neuron differentiation GO:0045664 208 0.022
regulation of muscle system process GO:0090257 79 0.022
reactive nitrogen species metabolic process GO:2001057 1 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
striated muscle tissue development GO:0014706 58 0.022
cellular homeostasis GO:0019725 252 0.022
positive regulation of signal transduction GO:0009967 175 0.022
response to corticosterone GO:0051412 40 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
Rat
regulation of phosphate metabolic process GO:0019220 349 0.021
positive regulation of homeostatic process GO:0032846 49 0.021
multicellular organism growth GO:0035264 1 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
negative regulation of molecular function GO:0044092 133 0.021
regulation of blood circulation GO:1903522 110 0.021
regeneration GO:0031099 163 0.021
chemotaxis GO:0006935 66 0.021
rna biosynthetic process GO:0032774 380 0.021
oligopeptide transport GO:0006857 4 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
response to chromate GO:0046687 3 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to carbohydrate GO:0009743 183 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
immune system development GO:0002520 41 0.020
localization of cell GO:0051674 202 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
negative regulation of catalytic activity GO:0043086 103 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
Rat
multicellular organismal signaling GO:0035637 44 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.019
neurological system process GO:0050877 219 0.019
protein transport GO:0015031 132 0.019
cellular response to lipid GO:0071396 201 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.019
organic substance catabolic process GO:1901575 316 0.019
multi multicellular organism process GO:0044706 138 0.019
response to food GO:0032094 27 0.019
female pregnancy GO:0007565 122 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to vitamin GO:0033273 131 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
nucleocytoplasmic transport GO:0006913 48 0.019
tissue development GO:0009888 252 0.019
organic hydroxy compound biosynthetic process GO:1901617 51 0.019
negative regulation of vasculature development GO:1901343 11 0.018
regulation of extracellular matrix constituent secretion GO:0003330 2 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.018
regulation of cell growth GO:0001558 85 0.018
anion transport GO:0006820 178 0.018
cellular response to external stimulus GO:0071496 118 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
monoamine transport GO:0015844 43 0.018
regulation of growth GO:0040008 105 0.018
regulation of serine type peptidase activity GO:1902571 1 0.018
positive regulation of camp biosynthetic process GO:0030819 28 0.018
cellular component movement GO:0006928 248 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
Rat
respiratory system process GO:0003016 3 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
Rat
reproductive process GO:0022414 372 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cell growth GO:0016049 104 0.017
organelle organization GO:0006996 266 0.017
response to peptide GO:1901652 292 0.017
positive regulation of ion transport GO:0043270 94 0.017
cellular catabolic process GO:0044248 295 0.017
negative regulation of cell death GO:0060548 229 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
chemical homeostasis GO:0048878 292 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
protein targeting GO:0006605 61 0.016
temperature homeostasis GO:0001659 17 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
muscle tissue development GO:0060537 58 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of neurological system process GO:0031644 43 0.015
regulation of transmembrane transport GO:0034762 122 0.015
sodium ion transport GO:0006814 82 0.015
locomotion GO:0040011 237 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
nucleic acid templated transcription GO:0097659 379 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of signaling GO:0023057 157 0.015
organic acid transport GO:0015849 116 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
Rat
leukocyte differentiation GO:0002521 30 0.015
transcription dna templated GO:0006351 377 0.015
intracellular protein transport GO:0006886 79 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
brain renin angiotensin system GO:0002035 3 0.014
alcohol metabolic process GO:0006066 77 0.014
organic acid biosynthetic process GO:0016053 83 0.014
organophosphate catabolic process GO:0046434 148 0.014
artery smooth muscle contraction GO:0014824 4 0.014
inflammatory response GO:0006954 150 0.014
secretion GO:0046903 307 0.014
cytoplasmic transport GO:0016482 115 0.014
proteolysis GO:0006508 175 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cellular macromolecule localization GO:0070727 122 0.014
membrane organization GO:0061024 94 0.014
cellular protein localization GO:0034613 122 0.014
secretion by cell GO:0032940 248 0.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
monocarboxylic acid transport GO:0015718 52 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
single organism catabolic process GO:0044712 283 0.013
trichloroethylene metabolic process GO:0018979 1 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
neutral lipid metabolic process GO:0006638 21 0.013
coenzyme metabolic process GO:0006732 86 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of fibroblast proliferation GO:0048146 15 0.013
regulation of anatomical structure size GO:0090066 135 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
regulation of phosphorylation GO:0042325 248 0.013
protein homooligomerization GO:0051260 91 0.013
cellular response to oxidative stress GO:0034599 76 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of innate immune response GO:0045824 4 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
regulation of membrane potential GO:0042391 110 0.012
multi organism reproductive process GO:0044703 262 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of peptide transport GO:0090087 87 0.012
response to hypoxia GO:0001666 231 0.012
reproduction GO:0000003 245 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of blood vessel morphogenesis GO:2000181 10 0.012
single organism biosynthetic process GO:0044711 342 0.012
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cellular ketone metabolic process GO:0042180 51 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
muscle cell proliferation GO:0033002 84 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.011
lipid biosynthetic process GO:0008610 128 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
fatty acid metabolic process GO:0006631 99 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
vasculature development GO:0001944 70 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
lipid storage GO:0019915 1 0.011
camp metabolic process GO:0046058 63 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
neuronal action potential GO:0019228 35 0.011
single organism nuclear import GO:1902593 35 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
Rat
regulation of secretion GO:0051046 224 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of transcription dna templated GO:0006355 374 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
biological adhesion GO:0022610 110 0.011
forebrain development GO:0030900 98 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
fatty acid transport GO:0015908 25 0.011
fertilization GO:0009566 3 0.011
positive regulation of gene expression GO:0010628 244 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to testosterone GO:0033574 55 0.011
response to monosaccharide GO:0034284 159 0.011
response to glucose GO:0009749 136 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
rho protein signal transduction GO:0007266 11 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of leukocyte mediated immunity GO:0002703 19 0.010
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
establishment of protein localization to organelle GO:0072594 44 0.010
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
extracellular matrix constituent secretion GO:0070278 4 0.010
response to peptide hormone GO:0043434 278 0.010
positive regulation of protein modification process GO:0031401 142 0.010

Gucy1b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011