Rattus norvegicus

0 known processes

Gzmc

granzyme C

(Aliases: Rnpk4,Rnpk-4)

Gzmc biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to cytokine stimulus GO:0071345 127 0.164
regulation of necroptotic process GO:0060544 2 0.121
regulation of neurogenesis GO:0050767 247 0.114
amine metabolic process GO:0009308 38 0.108
regulation of cell development GO:0060284 263 0.103
cellular amino acid metabolic process GO:0006520 107 0.097
response to bacterium GO:0009617 200 0.094
t cell chemotaxis GO:0010818 2 0.091
response to cytokine GO:0034097 215 0.087
regulation of neuron differentiation GO:0045664 208 0.086
positive regulation of cell development GO:0010720 176 0.085
positive regulation of necrotic cell death GO:0010940 4 0.081
organic acid metabolic process GO:0006082 292 0.080
cellular response to alkaloid GO:0071312 25 0.079
response to corticosteroid GO:0031960 235 0.075
response to other organism GO:0051707 220 0.074
regulation of cell differentiation GO:0045595 320 0.073
pseudopodium organization GO:0031268 3 0.072
response to nicotine GO:0035094 51 0.070
response to oxidative stress GO:0006979 186 0.070
response to wounding GO:0009611 254 0.067
regulation of metal ion transport GO:0010959 118 0.066
regulation of nervous system development GO:0051960 264 0.064
carboxylic acid metabolic process GO:0019752 289 0.063
cellular component biogenesis GO:0044085 368 0.063
anatomical structure morphogenesis GO:0009653 298 0.061
neuron death GO:0070997 127 0.061
cell projection organization GO:0030030 302 0.061
positive regulation of nervous system development GO:0051962 178 0.058
response to vitamin GO:0033273 131 0.055
response to amino acid GO:0043200 75 0.055
response to extracellular stimulus GO:0009991 380 0.054
response to external biotic stimulus GO:0043207 221 0.053
cellular response to endogenous stimulus GO:0071495 377 0.052
cellular amine metabolic process GO:0044106 38 0.051
eosinophil migration GO:0072677 3 0.051
innate immune response GO:0045087 35 0.050
response to molecule of bacterial origin GO:0002237 194 0.050
intracellular signal transduction GO:0035556 314 0.050
regulation of cellular ketone metabolic process GO:0010565 27 0.049
peptidyl amino acid modification GO:0018193 126 0.048
response to growth factor GO:0070848 189 0.046
protein complex subunit organization GO:0071822 302 0.046
anion transport GO:0006820 178 0.045
programmed necrotic cell death GO:0097300 2 0.045
localization of cell GO:0051674 202 0.044
lipid metabolic process GO:0006629 283 0.044
cellular component assembly GO:0022607 360 0.043
leukocyte chemotaxis GO:0030595 22 0.043
response to ketone GO:1901654 182 0.042
positive regulation of cell communication GO:0010647 271 0.041
positive regulation of cell differentiation GO:0045597 217 0.041
taxis GO:0042330 67 0.040
regulation of body fluid levels GO:0050878 90 0.039
cellular ketone metabolic process GO:0042180 51 0.039
regulation of neuron death GO:1901214 115 0.038
appendage morphogenesis GO:0035107 4 0.038
cellular response to tumor necrosis factor GO:0071356 46 0.037
aging GO:0007568 241 0.037
regulation of molecular function GO:0065009 398 0.037
developmental growth GO:0048589 100 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
monocarboxylic acid metabolic process GO:0032787 152 0.036
response to biotic stimulus GO:0009607 226 0.036
homeostatic process GO:0042592 331 0.036
regulation of intracellular signal transduction GO:1902531 218 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
pseudopodium assembly GO:0031269 3 0.033
urogenital system development GO:0001655 78 0.033
negative regulation of cell differentiation GO:0045596 99 0.033
chemical homeostasis GO:0048878 292 0.033
circulatory system process GO:0003013 183 0.033
cellular response to vitamin k GO:0071307 1 0.032
cellular response to organic cyclic compound GO:0071407 202 0.032
protein oligomerization GO:0051259 191 0.032
response to alkaloid GO:0043279 132 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
cellular chemical homeostasis GO:0055082 247 0.032
cellular lipid metabolic process GO:0044255 208 0.031
organophosphate metabolic process GO:0019637 370 0.031
positive regulation of neuron differentiation GO:0045666 126 0.031
oxoacid metabolic process GO:0043436 290 0.031
response to glucocorticoid GO:0051384 223 0.031
protein complex biogenesis GO:0070271 263 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
mast cell migration GO:0097531 4 0.030
regulation of ion transport GO:0043269 245 0.030
positive regulation of cell proliferation GO:0008284 249 0.029
metal ion transport GO:0030001 289 0.029
regulation of cell proliferation GO:0042127 359 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
positive regulation of apoptotic process GO:0043065 154 0.029
positive regulation of intracellular signal transduction GO:1902533 138 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
rhythmic process GO:0048511 156 0.028
tube development GO:0035295 89 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
wound healing GO:0042060 122 0.028
apoptotic process GO:0006915 381 0.028
positive regulation of signal transduction GO:0009967 175 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
mast cell chemotaxis GO:0002551 4 0.027
negative regulation of viral process GO:0048525 4 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
secretion by cell GO:0032940 248 0.027
l glutamate import GO:0051938 2 0.027
regulation of cellular localization GO:0060341 263 0.027
positive regulation of molecular function GO:0044093 230 0.026
defense response GO:0006952 194 0.026
intracellular transport GO:0046907 185 0.026
cellular response to external stimulus GO:0071496 118 0.026
neuron development GO:0048666 286 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
eye morphogenesis GO:0048592 4 0.025
cellular response to lipid GO:0071396 201 0.025
chemotaxis GO:0006935 66 0.025
cellular response to stress GO:0033554 269 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
locomotor rhythm GO:0045475 1 0.024
epithelium development GO:0060429 96 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
peptidyl tyrosine modification GO:0018212 72 0.023
regulation of cell projection organization GO:0031344 175 0.023
macromolecular complex assembly GO:0065003 273 0.023
vesicle mediated transport GO:0016192 181 0.023
kidney development GO:0001822 67 0.023
limb morphogenesis GO:0035108 4 0.023
response to axon injury GO:0048678 59 0.023
response to blue light GO:0009637 1 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
positive regulation of t cell migration GO:2000406 1 0.023
response to nutrient levels GO:0031667 370 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
organic acid transport GO:0015849 116 0.022
protein phosphorylation GO:0006468 345 0.022
regeneration GO:0031099 163 0.022
positive regulation of necroptotic process GO:0060545 2 0.022
response to tumor necrosis factor GO:0034612 56 0.022
blood circulation GO:0008015 183 0.022
lipid biosynthetic process GO:0008610 128 0.021
negative regulation of neuron death GO:1901215 69 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cellular component movement GO:0006928 248 0.021
response to inorganic substance GO:0010035 377 0.021
ethanolamine containing compound metabolic process GO:0042439 14 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
helper t cell diapedesis GO:0035685 1 0.021
neuron projection development GO:0031175 273 0.020
positive regulation of cell death GO:0010942 184 0.020
phospholipid metabolic process GO:0006644 61 0.020
regulation of axonogenesis GO:0050770 37 0.020
synaptic growth at neuromuscular junction GO:0051124 1 0.020
regulation of cell motility GO:2000145 131 0.020
vascular process in circulatory system GO:0003018 96 0.020
positive regulation of gene expression GO:0010628 244 0.020
purine containing compound metabolic process GO:0072521 253 0.020
cytoplasmic transport GO:0016482 115 0.020
immune system process GO:0002376 204 0.020
neuron differentiation GO:0030182 368 0.019
regulation of lymphocyte migration GO:2000401 1 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
protein complex assembly GO:0006461 263 0.019
interleukin 18 production GO:0032621 1 0.019
catabolic process GO:0009056 351 0.019
negative regulation of molecular function GO:0044092 133 0.019
cell migration GO:0016477 197 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
t cell migration GO:0072678 2 0.019
single organism intracellular transport GO:1902582 166 0.019
immune response GO:0006955 104 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
response to peptide hormone GO:0043434 278 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
eosinophil chemotaxis GO:0048245 3 0.019
fatty acid metabolic process GO:0006631 99 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
response to camp GO:0051591 91 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of transport GO:0051050 245 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
cation homeostasis GO:0055080 195 0.018
necroptotic process GO:0070266 2 0.018
sensory perception of pain GO:0019233 73 0.018
negative regulation of neuron differentiation GO:0045665 62 0.018
cation transport GO:0006812 382 0.018
circadian rhythm GO:0007623 88 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
response to metal ion GO:0010038 253 0.017
protein homooligomerization GO:0051260 91 0.017
cellular response to acid chemical GO:0071229 75 0.017
cellular response to metal ion GO:0071248 55 0.017
response to activity GO:0014823 73 0.017
organelle organization GO:0006996 266 0.016
regulation of lymphocyte chemotaxis GO:1901623 1 0.016
establishment of protein localization GO:0045184 141 0.016
regulation of neuron projection development GO:0010975 161 0.016
interleukin 1 alpha production GO:0032610 1 0.016
leukocyte activation GO:0045321 76 0.016
positive regulation of response to wounding GO:1903036 34 0.016
multicellular organismal homeostasis GO:0048871 49 0.016
regulation of programmed cell death GO:0043067 341 0.016
cellular response to vitamin GO:0071295 21 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
proteolysis GO:0006508 175 0.016
Human
response to alkyl hydroperoxide GO:0033195 1 0.016
retinal ganglion cell axon guidance GO:0031290 1 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
sodium ion transport GO:0006814 82 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of response to external stimulus GO:0032101 106 0.016
jak stat cascade GO:0007259 26 0.015
single organism reproductive process GO:0044702 297 0.015
cell growth GO:0016049 104 0.015
regulation of protein metabolic process GO:0051246 289 0.015
lymphocyte chemotaxis GO:0048247 3 0.015
small molecule biosynthetic process GO:0044283 124 0.015
epithelial cell proliferation GO:0050673 54 0.015
organelle localization GO:0051640 55 0.015
single organism biosynthetic process GO:0044711 342 0.015
exocytosis GO:0006887 60 0.015
cellular homeostasis GO:0019725 252 0.015
t helper 1 cell diapedesis GO:0035688 1 0.015
response to glucose GO:0009749 136 0.015
tissue development GO:0009888 252 0.015
gland development GO:0048732 155 0.014
response to hexose GO:0009746 144 0.014
single organism catabolic process GO:0044712 283 0.014
positive regulation of immune system process GO:0002684 90 0.014
regulation of signal transduction GO:0009966 318 0.014
regulation of immune system process GO:0002682 123 0.014
negative regulation of cell development GO:0010721 82 0.014
sequestering of calcium ion GO:0051208 8 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
positive regulation of potassium ion transport GO:0043268 13 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
cell type specific apoptotic process GO:0097285 134 0.014
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.014
locomotion GO:0040011 237 0.013
reproductive process GO:0022414 372 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
axis specification GO:0009798 4 0.013
monosaccharide metabolic process GO:0005996 61 0.013
regulation of cellular component organization GO:0051128 368 0.013
response to tumor cell GO:0002347 4 0.013
t helper 1 cell extravasation GO:0035687 1 0.013
negative regulation of cell death GO:0060548 229 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
negative regulation of signal transduction GO:0009968 83 0.013
response to insulin GO:0032868 133 0.013
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.013
response to hydrogen peroxide GO:0042542 89 0.013
cellular cation homeostasis GO:0030003 180 0.013
regulation of interleukin 1 alpha production GO:0032650 1 0.013
forebrain development GO:0030900 98 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
response to transforming growth factor beta GO:0071559 46 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
myeloid leukocyte migration GO:0097529 20 0.013
response to peptide GO:1901652 292 0.013
positive regulation of interleukin 18 production GO:0032741 1 0.012
regulation of catalytic activity GO:0050790 304 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
optic nerve development GO:0021554 3 0.012
endocrine system development GO:0035270 30 0.012
protein maturation GO:0051604 68 0.012
glucose homeostasis GO:0042593 75 0.012
behavior GO:0007610 205 0.012
cardiac chamber development GO:0003205 1 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of calcium ion transport GO:0051924 77 0.012
regulation of anatomical structure size GO:0090066 135 0.012
respiratory system development GO:0060541 45 0.012
cell projection morphogenesis GO:0048858 123 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 2 0.012
negative regulation of l glutamate transport GO:0002037 1 0.012
programmed cell death GO:0012501 392 0.012
positive regulation of brown fat cell proliferation GO:0070349 1 0.012
regulation of secretion by cell GO:1903530 208 0.012
cellular response to oxidative stress GO:0034599 76 0.012
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of fat cell proliferation GO:0070344 1 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
muscle system process GO:0003012 115 0.011
dibenzo p dioxin metabolic process GO:0018894 10 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
cellular response to inorganic substance GO:0071241 65 0.011
positive regulation of secretion GO:0051047 140 0.011
leukocyte migration GO:0050900 38 0.011
metanephric s shaped body morphogenesis GO:0072284 2 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
organic anion transport GO:0015711 132 0.011
regulation of growth GO:0040008 105 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
viral transcription GO:0019083 2 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of hydrolase activity GO:0051336 143 0.011
axonogenesis GO:0007409 71 0.011
negative regulation of nervous system development GO:0051961 79 0.011
phenol containing compound metabolic process GO:0018958 30 0.011
regulation of protein localization GO:0032880 81 0.011
response to lipopolysaccharide GO:0032496 191 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
regulation of cellular component movement GO:0051270 150 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
blood vessel morphogenesis GO:0048514 58 0.011
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.011
regulation of membrane potential GO:0042391 110 0.011
cellular response to nutrient levels GO:0031669 60 0.011
regulation of interferon gamma production GO:0032649 3 0.011
cellular response to interferon gamma GO:0071346 14 0.011
divalent inorganic cation transport GO:0072511 134 0.011
sulfur compound metabolic process GO:0006790 70 0.010
protein transport GO:0015031 132 0.010
negative regulation of innate immune response GO:0045824 4 0.010
salivary gland development GO:0007431 3 0.010
sex differentiation GO:0007548 113 0.010
response to ethanol GO:0045471 162 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
response to hypoxia GO:0001666 231 0.010
response to ionizing radiation GO:0010212 59 0.010
response to acid chemical GO:0001101 222 0.010
regulation of sodium ion transport GO:0002028 21 0.010
regulation of immune response to tumor cell GO:0002837 3 0.010
cellular response to alcohol GO:0097306 87 0.010
calcium ion homeostasis GO:0055074 162 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010

Gzmc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org