Rattus norvegicus

0 known processes

Hbb-b1

hemoglobin, beta adult major chain

(Aliases: MGC72973)

Hbb-b1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hydrogen peroxide metabolic process GO:0042743 13 0.947
glutathione metabolic process GO:0006749 15 0.938
Rat
peptide metabolic process GO:0006518 32 0.668
Rat
erythrocyte differentiation GO:0030218 1 0.568
cellular amide metabolic process GO:0043603 44 0.421
Rat
homeostatic process GO:0042592 331 0.410
carboxylic acid metabolic process GO:0019752 289 0.397
Rat
oxoacid metabolic process GO:0043436 290 0.315
Rat
protein complex biogenesis GO:0070271 263 0.313
Rat
cellular component assembly GO:0022607 360 0.305
Rat
regulation of blood pressure GO:0008217 83 0.267
organic acid metabolic process GO:0006082 292 0.214
Rat
protein heterooligomerization GO:0051291 89 0.210
Rat
sensory perception of pain GO:0019233 73 0.196
gas transport GO:0015669 4 0.192
Rat
blood circulation GO:0008015 183 0.182
cellular modified amino acid metabolic process GO:0006575 61 0.179
Rat
response to oxidative stress GO:0006979 186 0.166
cellular catabolic process GO:0044248 295 0.165
cellular response to oxygen containing compound GO:1901701 386 0.163
regulation of sensory perception GO:0051931 29 0.157
macromolecular complex assembly GO:0065003 273 0.148
Rat
cellular amino acid metabolic process GO:0006520 107 0.146
Rat
cellular response to stress GO:0033554 269 0.140
homeostasis of number of cells GO:0048872 10 0.134
response to inorganic substance GO:0010035 377 0.131
macromolecular complex subunit organization GO:0043933 339 0.129
Rat
regulation of translational initiation GO:0006446 6 0.124
cellular response to oxidative stress GO:0034599 76 0.123
protein complex subunit organization GO:0071822 302 0.120
Rat
protein complex assembly GO:0006461 263 0.111
Rat
cellular component biogenesis GO:0044085 368 0.106
Rat
secretion GO:0046903 307 0.104
cellular component movement GO:0006928 248 0.085
protein oligomerization GO:0051259 191 0.074
Rat
immune system process GO:0002376 204 0.070
regulation of neurological system process GO:0031644 43 0.068
neurological system process GO:0050877 219 0.066
catabolic process GO:0009056 351 0.064
reactive oxygen species metabolic process GO:0072593 37 0.063
cell motility GO:0048870 202 0.063
response to biotic stimulus GO:0009607 226 0.061
response to other organism GO:0051707 220 0.061
single organism catabolic process GO:0044712 283 0.061
protein phosphorylation GO:0006468 345 0.059
hematopoietic or lymphoid organ development GO:0048534 36 0.058
regulation of phosphorylation GO:0042325 248 0.055
response to oxygen levels GO:0070482 265 0.055
regulation of sensory perception of pain GO:0051930 29 0.054
cellular response to hydrogen peroxide GO:0070301 42 0.054
myeloid cell development GO:0061515 1 0.053
regulation of system process GO:0044057 208 0.053
apoptotic process GO:0006915 381 0.052
cellular response to reactive oxygen species GO:0034614 55 0.051
response to stilbenoid GO:0035634 1 0.045
synaptic transmission GO:0007268 235 0.045
single organism biosynthetic process GO:0044711 342 0.044
hemopoiesis GO:0030097 34 0.042
negative regulation of blood pressure GO:0045776 29 0.042
response to hydrogen peroxide GO:0042542 89 0.042
response to nutrient levels GO:0031667 370 0.041
oxygen transport GO:0015671 2 0.041
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.040
immune system development GO:0002520 41 0.039
programmed cell death GO:0012501 392 0.039
regulation of cellular protein metabolic process GO:0032268 267 0.038
positive regulation of cell death GO:0010942 184 0.038
response to extracellular stimulus GO:0009991 380 0.037
circulatory system process GO:0003013 183 0.036
oxidation reduction process GO:0055114 304 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
cellular response to lipid GO:0071396 201 0.035
response to molecule of bacterial origin GO:0002237 194 0.034
regulation of protein metabolic process GO:0051246 289 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
regeneration GO:0031099 163 0.031
cell projection organization GO:0030030 302 0.031
inorganic cation transmembrane transport GO:0098662 202 0.030
regulation of molecular function GO:0065009 398 0.030
cellular homeostasis GO:0019725 252 0.030
regulation of protein modification process GO:0031399 194 0.030
response to nutrient GO:0007584 248 0.030
response to lead ion GO:0010288 33 0.029
response to external biotic stimulus GO:0043207 221 0.029
nucleotide metabolic process GO:0009117 279 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
response to glucocorticoid GO:0051384 223 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
reproductive process GO:0022414 372 0.028
myeloid cell homeostasis GO:0002262 6 0.028
regulation of protein phosphorylation GO:0001932 183 0.027
regulation of cellular component organization GO:0051128 368 0.027
regulation of programmed cell death GO:0043067 341 0.027
regulation of secretion GO:0051046 224 0.026
response to hypoxia GO:0001666 231 0.026
regulation of secretion by cell GO:1903530 208 0.026
regulation of apoptotic process GO:0042981 335 0.025
chemotaxis GO:0006935 66 0.024
secretion by cell GO:0032940 248 0.024
cellular ion homeostasis GO:0006873 184 0.023
response to corticosteroid GO:0031960 235 0.023
positive regulation of transport GO:0051050 245 0.023
aging GO:0007568 241 0.023
regulation of response to wounding GO:1903034 69 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
nitrogen compound transport GO:0071705 229 0.023
positive regulation of developmental process GO:0051094 283 0.022
regulation of synaptic plasticity GO:0048167 70 0.022
metal ion transport GO:0030001 289 0.022
cellular cation homeostasis GO:0030003 180 0.022
regulation of hormone levels GO:0010817 187 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
rna metabolic process GO:0016070 406 0.022
multi organism reproductive process GO:0044703 262 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
metal ion homeostasis GO:0055065 186 0.021
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
organophosphate metabolic process GO:0019637 370 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
regulation of transcription dna templated GO:0006355 374 0.021
amine metabolic process GO:0009308 38 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of catalytic activity GO:0050790 304 0.021
gland development GO:0048732 155 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
response to wounding GO:0009611 254 0.020
cellular chemical homeostasis GO:0055082 247 0.020
negative regulation of metabolic process GO:0009892 331 0.020
response to bacterium GO:0009617 200 0.020
single organism reproductive process GO:0044702 297 0.020
hormone transport GO:0009914 121 0.020
regulation of cell proliferation GO:0042127 359 0.020
localization of cell GO:0051674 202 0.020
chemical homeostasis GO:0048878 292 0.020
head development GO:0060322 247 0.020
cell cell signaling GO:0007267 335 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
organ regeneration GO:0031100 101 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
response to monosaccharide GO:0034284 159 0.019
regulation of neurogenesis GO:0050767 247 0.019
cellular response to alcohol GO:0097306 87 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
locomotion GO:0040011 237 0.018
regulation of membrane potential GO:0042391 110 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
response to metal ion GO:0010038 253 0.018
developmental process involved in reproduction GO:0003006 159 0.018
macromolecule localization GO:0033036 252 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
regulation of response to external stimulus GO:0032101 106 0.018
heart morphogenesis GO:0003007 3 0.018
myeloid cell differentiation GO:0030099 22 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
positive regulation of gene expression GO:0010628 244 0.018
neuron differentiation GO:0030182 368 0.018
divalent inorganic cation transport GO:0072511 134 0.018
calcium ion transmembrane transport GO:0070588 70 0.018
regulation of nervous system development GO:0051960 264 0.017
behavior GO:0007610 205 0.017
cellular ketone metabolic process GO:0042180 51 0.017
sensory perception GO:0007600 101 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
cellular amine metabolic process GO:0044106 38 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.017
calcium ion homeostasis GO:0055074 162 0.017
translational initiation GO:0006413 8 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
response to reactive oxygen species GO:0000302 120 0.017
rna biosynthetic process GO:0032774 380 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
intracellular transport GO:0046907 185 0.017
regulation of hydrolase activity GO:0051336 143 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
multicellular organismal reproductive process GO:0048609 233 0.016
inflammatory response GO:0006954 150 0.016
central nervous system development GO:0007417 311 0.016
ion homeostasis GO:0050801 212 0.016
response to lipopolysaccharide GO:0032496 191 0.016
regulation of peptide transport GO:0090087 87 0.016
purine containing compound metabolic process GO:0072521 253 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
response to estrogen GO:0043627 232 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
regulation of ion transport GO:0043269 245 0.016
establishment of protein localization GO:0045184 141 0.016
ion transmembrane transport GO:0034220 365 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
regulation of cell differentiation GO:0045595 320 0.015
regulation of metal ion transport GO:0010959 118 0.015
reproduction GO:0000003 245 0.015
sexual reproduction GO:0019953 148 0.015
aromatic compound catabolic process GO:0019439 168 0.015
organic substance catabolic process GO:1901575 316 0.015
cation homeostasis GO:0055080 195 0.015
second messenger mediated signaling GO:0019932 51 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
response to alkaloid GO:0043279 132 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
transmembrane transport GO:0055085 412 0.014
cation transport GO:0006812 382 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
protein localization GO:0008104 191 0.014
response to mechanical stimulus GO:0009612 134 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
regulation of immune system process GO:0002682 123 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
organelle organization GO:0006996 266 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
erythrocyte homeostasis GO:0034101 2 0.014
positive regulation of cell development GO:0010720 176 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
negative regulation of cell death GO:0060548 229 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of transmembrane transport GO:0034762 122 0.014
response to glucose GO:0009749 136 0.014
transcription dna templated GO:0006351 377 0.013
granulocyte chemotaxis GO:0071621 15 0.013
regulation of cell projection organization GO:0031344 175 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
brain development GO:0007420 247 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of camp metabolic process GO:0030814 43 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
neuronal action potential GO:0019228 35 0.013
calcium ion transport GO:0006816 131 0.013
defense response GO:0006952 194 0.013
positive regulation of secretion GO:0051047 140 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
neuron projection development GO:0031175 273 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
gamete generation GO:0007276 124 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.013
positive regulation of signaling GO:0023056 270 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
regulation of rna metabolic process GO:0051252 391 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
positive regulation of molecular function GO:0044093 230 0.013
response to ketone GO:1901654 182 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
response to carbohydrate GO:0009743 183 0.013
lipid metabolic process GO:0006629 283 0.013
cytoplasmic transport GO:0016482 115 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
regulation of translational initiation in response to stress GO:0043558 4 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
cation transmembrane transport GO:0098655 263 0.012
peptide transport GO:0015833 97 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
signal release GO:0023061 145 0.012
amide transport GO:0042886 105 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
response to vitamin GO:0033273 131 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
membrane organization GO:0061024 94 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
neuron development GO:0048666 286 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
axis specification GO:0009798 4 0.012
eye morphogenesis GO:0048592 4 0.012
positive regulation of protein modification process GO:0031401 142 0.012
protein transport GO:0015031 132 0.012
regulation of synaptic transmission GO:0050804 141 0.012
negative regulation of transport GO:0051051 136 0.012
hormone secretion GO:0046879 115 0.012
camp metabolic process GO:0046058 63 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
rna localization GO:0006403 4 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of neuron projection development GO:0010975 161 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of hormone secretion GO:0046883 106 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
male gamete generation GO:0048232 99 0.011
multicellular organismal signaling GO:0035637 44 0.011
sex differentiation GO:0007548 113 0.011
anterior posterior pattern specification GO:0009952 1 0.011
regulation of peptide secretion GO:0002791 82 0.011
response to hexose GO:0009746 144 0.011
negative regulation of secretion GO:0051048 82 0.011
regulation of cellular component movement GO:0051270 150 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
tissue remodeling GO:0048771 40 0.011
actin filament based movement GO:0030048 16 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
positive regulation of cell communication GO:0010647 271 0.011
positive regulation of endothelial cell differentiation GO:0045603 2 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
response to tumor necrosis factor GO:0034612 56 0.011
chemosensory behavior GO:0007635 2 0.011
halogenated hydrocarbon metabolic process GO:0042197 4 0.011
cell cycle checkpoint GO:0000075 2 0.011
chromosome segregation GO:0007059 2 0.011
peptide secretion GO:0002790 86 0.011
spindle organization GO:0007051 2 0.011
regulation of calcium ion transport GO:0051924 77 0.011
gonad development GO:0008406 104 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
action potential GO:0001508 54 0.011
response to estradiol GO:0032355 164 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
negative regulation of innate immune response GO:0045824 4 0.010
monosaccharide metabolic process GO:0005996 61 0.010
cardiovascular system development GO:0072358 134 0.010
regulation of neuron differentiation GO:0045664 208 0.010
response to cold GO:0009409 29 0.010
nucleoside metabolic process GO:0009116 179 0.010
organic acid catabolic process GO:0016054 49 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
male gonad development GO:0008584 59 0.010
single organism organelle organization GO:1902589 180 0.010
detection of calcium ion GO:0005513 1 0.010
cell chemotaxis GO:0060326 31 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010

Hbb-b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.024
musculoskeletal system disease DOID:17 0 0.022
disease of anatomical entity DOID:7 0 0.022
muscular disease DOID:0080000 0 0.022
nervous system disease DOID:863 0 0.018
cardiovascular system disease DOID:1287 0 0.014
central nervous system disease DOID:331 0 0.013
muscle tissue disease DOID:66 0 0.012