Rattus norvegicus

12 known processes

Hbe1

hemoglobin, epsilon 1

Hbe1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphorus metabolic process GO:0051174 349 0.286
regulation of phosphorylation GO:0042325 248 0.247
localization of cell GO:0051674 202 0.243
positive regulation of intracellular signal transduction GO:1902533 138 0.224
cation transport GO:0006812 382 0.213
regulation of ion transport GO:0043269 245 0.212
positive regulation of signaling GO:0023056 270 0.194
positive regulation of phosphate metabolic process GO:0045937 262 0.188
cellular ion homeostasis GO:0006873 184 0.187
inorganic cation transmembrane transport GO:0098662 202 0.186
positive regulation of signal transduction GO:0009967 175 0.185
regulation of signal transduction GO:0009966 318 0.178
single organism reproductive process GO:0044702 297 0.176
positive regulation of cell communication GO:0010647 271 0.170
cellular response to organic cyclic compound GO:0071407 202 0.162
cell cell signaling GO:0007267 335 0.158
inorganic ion transmembrane transport GO:0098660 229 0.156
neuron apoptotic process GO:0051402 88 0.156
positive regulation of phosphorus metabolic process GO:0010562 262 0.154
wound healing GO:0042060 122 0.145
monovalent inorganic cation transport GO:0015672 172 0.140
regulation of mapk cascade GO:0043408 116 0.138
immune system process GO:0002376 204 0.131
homeostatic process GO:0042592 331 0.124
cation transmembrane transport GO:0098655 263 0.123
cellular divalent inorganic cation homeostasis GO:0072503 162 0.119
negative regulation of cell death GO:0060548 229 0.119
response to hypoxia GO:0001666 231 0.114
cellular chemical homeostasis GO:0055082 247 0.112
central nervous system development GO:0007417 311 0.112
regulation of intracellular signal transduction GO:1902531 218 0.104
response to inorganic substance GO:0010035 377 0.103
muscle system process GO:0003012 115 0.103
vesicle mediated transport GO:0016192 181 0.100
regulation of phosphate metabolic process GO:0019220 349 0.097
tissue development GO:0009888 252 0.095
positive regulation of response to stimulus GO:0048584 285 0.093
macromolecular complex subunit organization GO:0043933 339 0.093
regulation of cellular component movement GO:0051270 150 0.091
regulation of locomotion GO:0040012 148 0.091
regulation of protein phosphorylation GO:0001932 183 0.087
intracellular signal transduction GO:0035556 314 0.085
response to estrogen GO:0043627 232 0.085
organophosphate metabolic process GO:0019637 370 0.084
regulation of protein modification process GO:0031399 194 0.082
cell type specific apoptotic process GO:0097285 134 0.081
positive regulation of cellular protein metabolic process GO:0032270 167 0.080
cardiovascular system development GO:0072358 134 0.079
regulation of membrane potential GO:0042391 110 0.079
neuron death GO:0070997 127 0.079
regulation of system process GO:0044057 208 0.078
cellular homeostasis GO:0019725 252 0.077
ion homeostasis GO:0050801 212 0.075
positive regulation of phosphorylation GO:0042327 177 0.074
calcium ion homeostasis GO:0055074 162 0.069
mapk cascade GO:0000165 140 0.067
transcription dna templated GO:0006351 377 0.067
Mouse
leukocyte activation GO:0045321 76 0.066
chemical homeostasis GO:0048878 292 0.065
anatomical structure morphogenesis GO:0009653 298 0.065
positive regulation of protein modification process GO:0031401 142 0.065
brain development GO:0007420 247 0.064
response to wounding GO:0009611 254 0.063
regulation of multicellular organismal development GO:2000026 376 0.063
defense response GO:0006952 194 0.063
regulation of protein metabolic process GO:0051246 289 0.062
rna metabolic process GO:0016070 406 0.062
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.060
regulation of cell migration GO:0030334 128 0.060
regulation of cellular protein metabolic process GO:0032268 267 0.060
response to purine containing compound GO:0014074 126 0.060
action potential GO:0001508 54 0.059
regulation of immune system process GO:0002682 123 0.058
response to growth factor GO:0070848 189 0.058
cell activation GO:0001775 97 0.057
regulation of secretion by cell GO:1903530 208 0.056
negative regulation of apoptotic process GO:0043066 181 0.055
positive regulation of transport GO:0051050 245 0.055
regulation of response to stress GO:0080134 126 0.055
developmental process involved in reproduction GO:0003006 159 0.054
positive regulation of stress activated mapk cascade GO:0032874 17 0.054
cellular cation homeostasis GO:0030003 180 0.054
regulation of molecular function GO:0065009 398 0.053
response to other organism GO:0051707 220 0.052
cellular response to oxygen containing compound GO:1901701 386 0.051
positive regulation of map kinase activity GO:0043406 46 0.051
protein autophosphorylation GO:0046777 66 0.051
regulation of apoptotic process GO:0042981 335 0.051
nucleic acid templated transcription GO:0097659 379 0.051
Mouse
neuron differentiation GO:0030182 368 0.051
cellular component morphogenesis GO:0032989 155 0.050
cation homeostasis GO:0055080 195 0.050
negative regulation of neutrophil apoptotic process GO:0033030 3 0.050
cell adhesion GO:0007155 110 0.050
gland development GO:0048732 155 0.050
rna biosynthetic process GO:0032774 380 0.050
Mouse
positive regulation of mapk cascade GO:0043410 92 0.049
response to extracellular stimulus GO:0009991 380 0.049
positive regulation of protein phosphorylation GO:0001934 135 0.048
immune system development GO:0002520 41 0.048
cellular component biogenesis GO:0044085 368 0.047
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.047
head development GO:0060322 247 0.047
programmed cell death GO:0012501 392 0.047
oxoacid metabolic process GO:0043436 290 0.047
Rat
amine metabolic process GO:0009308 38 0.046
negative regulation of programmed cell death GO:0043069 183 0.045
regulation of stress activated mapk cascade GO:0032872 23 0.045
immune response GO:0006955 104 0.045
protein oligomerization GO:0051259 191 0.045
inflammatory response GO:0006954 150 0.044
regulation of catalytic activity GO:0050790 304 0.044
cellular component assembly GO:0022607 360 0.044
cellular response to hormone stimulus GO:0032870 247 0.044
cell motility GO:0048870 202 0.044
secretion GO:0046903 307 0.043
positive regulation of multicellular organismal process GO:0051240 387 0.043
cytosolic calcium ion homeostasis GO:0051480 140 0.042
protein complex assembly GO:0006461 263 0.042
apoptotic process GO:0006915 381 0.041
cellular calcium ion homeostasis GO:0006874 160 0.041
endocytosis GO:0006897 84 0.041
cellular response to endogenous stimulus GO:0071495 377 0.040
organic acid metabolic process GO:0006082 292 0.039
Rat
ion transmembrane transport GO:0034220 365 0.039
response to biotic stimulus GO:0009607 226 0.038
organ morphogenesis GO:0009887 75 0.038
neutrophil apoptotic process GO:0001781 4 0.037
regulation of cellular localization GO:0060341 263 0.037
positive regulation of cellular component organization GO:0051130 200 0.036
regulation of neuron apoptotic process GO:0043523 83 0.036
muscle contraction GO:0006936 88 0.036
carboxylic acid transport GO:0046942 115 0.036
neurological system process GO:0050877 219 0.036
cellular component movement GO:0006928 248 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.035
myeloid leukocyte activation GO:0002274 36 0.035
carboxylic acid metabolic process GO:0019752 289 0.034
Rat
transmission of nerve impulse GO:0019226 42 0.034
organic anion transport GO:0015711 132 0.034
response to bacterium GO:0009617 200 0.034
sensory perception of pain GO:0019233 73 0.033
hematopoietic or lymphoid organ development GO:0048534 36 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.033
single organism biosynthetic process GO:0044711 342 0.033
cellular amine metabolic process GO:0044106 38 0.033
anion transport GO:0006820 178 0.033
lipid metabolic process GO:0006629 283 0.033
regulation of cellular response to stress GO:0080135 49 0.033
cell migration GO:0016477 197 0.032
positive regulation of jnk cascade GO:0046330 13 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
response to oxygen levels GO:0070482 265 0.031
neuron projection development GO:0031175 273 0.031
response to acid chemical GO:0001101 222 0.031
positive regulation of biosynthetic process GO:0009891 319 0.030
response to peptide hormone GO:0043434 278 0.030
positive regulation of developmental process GO:0051094 283 0.030
transmembrane transport GO:0055085 412 0.030
regulation of homeostatic process GO:0032844 101 0.030
cellular response to stress GO:0033554 269 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
positive regulation of gene expression GO:0010628 244 0.029
regulation of cytokine production GO:0001817 56 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
biological adhesion GO:0022610 110 0.027
response to estradiol GO:0032355 164 0.027
response to external biotic stimulus GO:0043207 221 0.026
protein complex subunit organization GO:0071822 302 0.026
cellular ketone metabolic process GO:0042180 51 0.026
heart morphogenesis GO:0003007 3 0.025
positive regulation of cytokine production GO:0001819 42 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
response to organophosphorus GO:0046683 102 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
regulation of anion transport GO:0044070 43 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
cellular catabolic process GO:0044248 295 0.024
reproductive structure development GO:0048608 128 0.023
positive regulation of molecular function GO:0044093 230 0.023
intracellular transport GO:0046907 185 0.023
response to metal ion GO:0010038 253 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
response to monosaccharide GO:0034284 159 0.023
regulation of rna biosynthetic process GO:2001141 381 0.022
Mouse
regulation of programmed cell death GO:0043067 341 0.022
response to nutrient levels GO:0031667 370 0.022
actin filament based process GO:0030029 86 0.022
single organism intracellular transport GO:1902582 166 0.022
neuron development GO:0048666 286 0.022
hemopoiesis GO:0030097 34 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of cell motility GO:2000145 131 0.021
single organism organelle organization GO:1902589 180 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
multicellular organismal signaling GO:0035637 44 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
glycerolipid metabolic process GO:0046486 67 0.020
negative regulation of transport GO:0051051 136 0.020
response to decreased oxygen levels GO:0036293 237 0.020
non canonical wnt signaling pathway GO:0035567 3 0.020
cellular response to external stimulus GO:0071496 118 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
Mouse
regulation of cell differentiation GO:0045595 320 0.020
sensory perception GO:0007600 101 0.020
regulation of defense response GO:0031347 68 0.020
circulatory system development GO:0072359 134 0.020
negative regulation of neuron apoptotic process GO:0043524 45 0.020
positive regulation of cell motility GO:2000147 97 0.020
coagulation GO:0050817 28 0.020
second messenger mediated signaling GO:0019932 51 0.019
circulatory system process GO:0003013 183 0.019
negative regulation of vesicle fusion GO:0031339 2 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
positive regulation of transferase activity GO:0051347 81 0.019
response to radiation GO:0009314 137 0.019
response to glucose GO:0009749 136 0.019
leukocyte chemotaxis GO:0030595 22 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
response to increased oxygen levels GO:0036296 45 0.018
nucleotide metabolic process GO:0009117 279 0.018
organelle organization GO:0006996 266 0.018
regulation of neutrophil apoptotic process GO:0033029 4 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
nitrogen compound transport GO:0071705 229 0.018
smooth muscle cell proliferation GO:0048659 77 0.018
sex differentiation GO:0007548 113 0.018
regulation of cell proliferation GO:0042127 359 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
locomotion GO:0040011 237 0.018
organic substance catabolic process GO:1901575 316 0.017
regulation of transcription dna templated GO:0006355 374 0.017
Mouse
response to lipopolysaccharide GO:0032496 191 0.017
response to fatty acid GO:0070542 65 0.017
positive regulation of cell adhesion GO:0045785 30 0.017
alcohol metabolic process GO:0006066 77 0.017
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.017
lipid biosynthetic process GO:0008610 128 0.017
regulation of response to wounding GO:1903034 69 0.017
response to hyperoxia GO:0055093 45 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
Mouse
sexual reproduction GO:0019953 148 0.017
macromolecule localization GO:0033036 252 0.017
response to hexose GO:0009746 144 0.016
cell projection organization GO:0030030 302 0.016
reproductive system development GO:0061458 128 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
neuronal action potential GO:0019228 35 0.016
protein complex biogenesis GO:0070271 263 0.016
negative regulation of immune system process GO:0002683 39 0.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
Mouse
regulation of chronic inflammatory response GO:0002676 3 0.016
skeletal system development GO:0001501 41 0.016
protein heterooligomerization GO:0051291 89 0.016
response to camp GO:0051591 91 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
cellular response to camp GO:0071320 26 0.015
defecation GO:0030421 1 0.015
cytoplasmic transport GO:0016482 115 0.015
osteoblast differentiation GO:0001649 26 0.015
t cell migration GO:0072678 2 0.015
sequestering of metal ion GO:0051238 9 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
reproduction GO:0000003 245 0.015
urogenital system development GO:0001655 78 0.015
metal ion transport GO:0030001 289 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
Mouse
synaptic transmission GO:0007268 235 0.015
myeloid leukocyte differentiation GO:0002573 20 0.015
respiratory system development GO:0060541 45 0.015
gamete generation GO:0007276 124 0.015
cytokine biosynthetic process GO:0042089 3 0.014
heart process GO:0003015 57 0.014
cellular response to lipid GO:0071396 201 0.014
regulation of neuron death GO:1901214 115 0.014
gliogenesis GO:0042063 93 0.014
myeloid cell differentiation GO:0030099 22 0.014
phospholipid metabolic process GO:0006644 61 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
cell chemotaxis GO:0060326 31 0.014
eye morphogenesis GO:0048592 4 0.014
regulation of map kinase activity GO:0043405 53 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
regulation of synaptic transmission GO:0050804 141 0.014
regulation of body fluid levels GO:0050878 90 0.014
single organism cell adhesion GO:0098602 46 0.014
macromolecular complex assembly GO:0065003 273 0.014
response to carbohydrate GO:0009743 183 0.014
leukocyte differentiation GO:0002521 30 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
anion transmembrane transport GO:0098656 77 0.013
regulation of jun kinase activity GO:0043506 10 0.013
regulation of epithelial cell migration GO:0010632 17 0.013
negative regulation of metabolic process GO:0009892 331 0.013
Mouse
regulation of muscle system process GO:0090257 79 0.013
organic acid transport GO:0015849 116 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
epithelial cell proliferation GO:0050673 54 0.013
regulation of neurological system process GO:0031644 43 0.013
positive regulation of epithelial cell proliferation GO:0050679 32 0.013
positive regulation of serotonin secretion GO:0014064 1 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Mouse
establishment of protein localization GO:0045184 141 0.013
sequestering of calcium ion GO:0051208 8 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of nervous system development GO:0051960 264 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of neuron apoptotic process GO:0043525 33 0.013
potassium ion transport GO:0006813 97 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
steroid metabolic process GO:0008202 73 0.013
negative regulation of locomotion GO:0040013 41 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
heterocycle catabolic process GO:0046700 167 0.012
response to cytokine GO:0034097 215 0.012
blood circulation GO:0008015 183 0.012
taxis GO:0042330 67 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
Mouse
positive regulation of locomotion GO:0040017 102 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
Mouse
cellular response to molecule of bacterial origin GO:0071219 56 0.012
response to oxidative stress GO:0006979 186 0.012
epithelium development GO:0060429 96 0.012
cytokine production GO:0001816 61 0.012
regulation of metal ion transport GO:0010959 118 0.012
positive regulation of smooth muscle cell migration GO:0014911 27 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cell cycle checkpoint GO:0000075 2 0.012
organelle localization GO:0051640 55 0.012
t cell chemotaxis GO:0010818 2 0.012
secretion by cell GO:0032940 248 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
response to glucocorticoid GO:0051384 223 0.012
axis specification GO:0009798 4 0.012
negative regulation of defecation GO:2000293 1 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
endoplasmic reticulum membrane organization GO:0090158 1 0.012
regeneration GO:0031099 163 0.011
detection of calcium ion GO:0005513 1 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
regulation of ion homeostasis GO:2000021 63 0.011
tube development GO:0035295 89 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
muscle organ development GO:0007517 50 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of heart contraction GO:0008016 48 0.011
positive regulation of neuron death GO:1901216 43 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
tissue morphogenesis GO:0048729 22 0.011
response to reactive oxygen species GO:0000302 120 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of rna metabolic process GO:0051252 391 0.011
Mouse
regulated secretory pathway GO:0045055 17 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
negative regulation of chronic inflammatory response GO:0002677 2 0.011
alcohol biosynthetic process GO:0046165 38 0.010
endomembrane system organization GO:0010256 48 0.010
single organism cellular localization GO:1902580 102 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
proteolysis GO:0006508 175 0.010
nucleobase containing small molecule metabolic process GO:0055086 316 0.010
cellular lipid metabolic process GO:0044255 208 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
Mouse
muscle structure development GO:0061061 87 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
hair follicle development GO:0001942 2 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
regulation of inflammatory response GO:0050727 48 0.010

Hbe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
hemolytic anemia DOID:583 0 0.012
normocytic anemia DOID:720 0 0.012
anemia DOID:2355 0 0.012