Rattus norvegicus

0 known processes

Hcn3

hyperpolarization-activated cyclic nucleotide-gated potassium channel 3

Hcn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.396
Human Mouse Rat
cation transmembrane transport GO:0098655 263 0.238
Human Mouse Rat
transmembrane transport GO:0055085 412 0.195
Human Mouse Rat
regulation of phosphate metabolic process GO:0019220 349 0.193
transcription dna templated GO:0006351 377 0.191
inorganic cation transmembrane transport GO:0098662 202 0.171
Human Mouse
central nervous system development GO:0007417 311 0.155
Rat
rna biosynthetic process GO:0032774 380 0.134
regulation of nucleic acid templated transcription GO:1903506 380 0.116
positive regulation of signal transduction GO:0009967 175 0.106
positive regulation of cell communication GO:0010647 271 0.105
rna metabolic process GO:0016070 406 0.095
regulation of signal transduction GO:0009966 318 0.091
nitrogen compound transport GO:0071705 229 0.090
regulation of rna metabolic process GO:0051252 391 0.086
positive regulation of signaling GO:0023056 270 0.085
protein phosphorylation GO:0006468 345 0.082
metal ion transport GO:0030001 289 0.078
Human Mouse
cellular component assembly GO:0022607 360 0.076
Rat
nucleic acid templated transcription GO:0097659 379 0.075
response to external biotic stimulus GO:0043207 221 0.074
protein localization GO:0008104 191 0.066
cellular component biogenesis GO:0044085 368 0.065
Rat
cell cell signaling GO:0007267 335 0.065
single organism intracellular transport GO:1902582 166 0.060
regulation of transcription dna templated GO:0006355 374 0.059
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 3 0.058
reproductive process GO:0022414 372 0.057
neurological system process GO:0050877 219 0.054
negative regulation of cellular metabolic process GO:0031324 281 0.054
sensory perception GO:0007600 101 0.053
response to cytokine GO:0034097 215 0.053
behavior GO:0007610 205 0.051
response to wounding GO:0009611 254 0.050
gonad development GO:0008406 104 0.049
positive regulation of protein modification process GO:0031401 142 0.048
macromolecule localization GO:0033036 252 0.046
negative regulation of metabolic process GO:0009892 331 0.045
macromolecular complex assembly GO:0065003 273 0.045
Rat
sodium ion transport GO:0006814 82 0.045
Human
organelle organization GO:0006996 266 0.045
positive regulation of biosynthetic process GO:0009891 319 0.045
locomotion GO:0040011 237 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.042
neuron differentiation GO:0030182 368 0.042
response to other organism GO:0051707 220 0.042
regulation of rna biosynthetic process GO:2001141 381 0.041
regulation of molecular function GO:0065009 398 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.040
positive regulation of intracellular signal transduction GO:1902533 138 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
intracellular signal transduction GO:0035556 314 0.040
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.040
regulation of intracellular signal transduction GO:1902531 218 0.039
aging GO:0007568 241 0.039
Rat
positive regulation of response to stimulus GO:0048584 285 0.039
neuron projection development GO:0031175 273 0.039
regulation of ion transport GO:0043269 245 0.038
Human Mouse
development of primary sexual characteristics GO:0045137 107 0.038
secretion by cell GO:0032940 248 0.037
positive regulation of phosphorylation GO:0042327 177 0.037
cellular amine metabolic process GO:0044106 38 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
regulation of organ formation GO:0003156 2 0.036
regulation of cellular component organization GO:0051128 368 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
response to lipopolysaccharide GO:0032496 191 0.035
protein complex subunit organization GO:0071822 302 0.034
Rat
regulation of transmembrane transport GO:0034762 122 0.034
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
negative regulation of gene expression GO:0010629 199 0.032
amine metabolic process GO:0009308 38 0.032
regulation of cell differentiation GO:0045595 320 0.032
response to light stimulus GO:0009416 52 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
regulation of neuron projection development GO:0010975 161 0.032
amino acid transport GO:0006865 70 0.032
protein complex biogenesis GO:0070271 263 0.031
Rat
regulation of secretion by cell GO:1903530 208 0.031
head development GO:0060322 247 0.031
Rat
regulation of phosphorylation GO:0042325 248 0.030
detection of stimulus GO:0051606 24 0.030
regulation of protein metabolic process GO:0051246 289 0.030
positive regulation of serotonin secretion GO:0014064 1 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
brain development GO:0007420 247 0.029
Rat
inorganic ion transmembrane transport GO:0098660 229 0.029
Human Mouse
regulation of transmembrane transporter activity GO:0022898 49 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of secretion GO:0051046 224 0.028
reactive nitrogen species metabolic process GO:2001057 1 0.028
regulation of neurogenesis GO:0050767 247 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
mapk cascade GO:0000165 140 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
immune effector process GO:0002252 53 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
intracellular transport GO:0046907 185 0.027
rhythmic process GO:0048511 156 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
defecation GO:0030421 1 0.026
protein oligomerization GO:0051259 191 0.026
Rat
single organism reproductive process GO:0044702 297 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
response to radiation GO:0009314 137 0.025
developmental induction GO:0031128 2 0.025
positive regulation of programmed cell death GO:0043068 157 0.024
regulation of mapk cascade GO:0043408 116 0.024
synaptic transmission GO:0007268 235 0.024
regulation of nervous system development GO:0051960 264 0.024
response to molecule of bacterial origin GO:0002237 194 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
regulation of cellular localization GO:0060341 263 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
sensory organ development GO:0007423 74 0.022
regulation of ion transmembrane transporter activity GO:0032412 48 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of cell projection organization GO:0031344 175 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
positive regulation of transport GO:0051050 245 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
regulation of ion transmembrane transport GO:0034765 121 0.020
Human Mouse
organic acid metabolic process GO:0006082 292 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.020
protein complex assembly GO:0006461 263 0.020
Rat
response to extracellular stimulus GO:0009991 380 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
muscle structure development GO:0061061 87 0.020
hematopoietic progenitor cell differentiation GO:0002244 2 0.020
negative regulation of neuron projection development GO:0010977 46 0.020
regulation of membrane potential GO:0042391 110 0.020
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.019
regulation of protein localization GO:0032880 81 0.019
reproduction GO:0000003 245 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
hormone secretion GO:0046879 115 0.019
response to bacterium GO:0009617 200 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
localization of cell GO:0051674 202 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
positive regulation of mast cell activation GO:0033005 4 0.018
sex differentiation GO:0007548 113 0.018
multicellular organism reproduction GO:0032504 233 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
developmental process involved in reproduction GO:0003006 159 0.017
regulation of protein modification process GO:0031399 194 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
tube development GO:0035295 89 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
sodium ion transmembrane transport GO:0035725 67 0.017
Human
developmental growth involved in morphogenesis GO:0060560 33 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
multi organism reproductive process GO:0044703 262 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
negative regulation of defecation GO:2000293 1 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
neuronal action potential GO:0019228 35 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
calcium ion transport GO:0006816 131 0.016
striated muscle tissue development GO:0014706 58 0.015
carboxylic acid transport GO:0046942 115 0.015
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.015
peptide secretion GO:0002790 86 0.015
cation transport GO:0006812 382 0.015
Human Mouse Rat
regulation of catalytic activity GO:0050790 304 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
sequestering of metal ion GO:0051238 9 0.015
positive regulation of gene expression GO:0010628 244 0.014
response to biotic stimulus GO:0009607 226 0.014
sensory perception of pain GO:0019233 73 0.014
protein transport GO:0015031 132 0.014
cellular component movement GO:0006928 248 0.014
organ induction GO:0001759 1 0.014
coronary vasculature morphogenesis GO:0060977 3 0.014
adult locomotory behavior GO:0008344 4 0.014
protein homooligomerization GO:0051260 91 0.014
peptidyl amino acid modification GO:0018193 126 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
negative regulation of cell communication GO:0010648 158 0.014
anterior posterior pattern specification GO:0009952 1 0.014
amide transport GO:0042886 105 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.013
cellular ketone metabolic process GO:0042180 51 0.013
cell projection organization GO:0030030 302 0.013
specification of organ identity GO:0010092 2 0.013
response to axon injury GO:0048678 59 0.013
regulation of neurotransmitter uptake GO:0051580 1 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
cytoplasmic transport GO:0016482 115 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
circadian rhythm GO:0007623 88 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
male sex differentiation GO:0046661 64 0.013
positive regulation of ion transport GO:0043270 94 0.012
regulation of protein transport GO:0051223 68 0.012
positive regulation of developmental process GO:0051094 283 0.012
negative regulation of molecular function GO:0044092 133 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
response to growth factor GO:0070848 189 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of organelle organization GO:0033043 80 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
regeneration GO:0031099 163 0.012
single organism cellular localization GO:1902580 102 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
divalent inorganic cation transport GO:0072511 134 0.012
reproductive structure development GO:0048608 128 0.012
negative regulation of signaling GO:0023057 157 0.012
defense response GO:0006952 194 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
sensory perception of light stimulus GO:0050953 3 0.012
regulation of cation channel activity GO:2001257 23 0.012
erk1 and erk2 cascade GO:0070371 48 0.012
gamete generation GO:0007276 124 0.012
motor neuron axon guidance GO:0008045 1 0.012
neuromuscular process GO:0050905 2 0.012
single organism organelle organization GO:1902589 180 0.012
regulation of developmental growth GO:0048638 45 0.012
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
locomotory behavior GO:0007626 15 0.012
tube formation GO:0035148 3 0.012
transmission of nerve impulse GO:0019226 42 0.012
developmental growth GO:0048589 100 0.011
cellular ion homeostasis GO:0006873 184 0.011
Rat
regulation of locomotion GO:0040012 148 0.011
regulation of growth GO:0040008 105 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of metal ion transport GO:0010959 118 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of cell development GO:0060284 263 0.011
organ formation GO:0048645 3 0.011
axis specification GO:0009798 4 0.011
positive regulation of molecular function GO:0044093 230 0.011
negative regulation of luteinizing hormone secretion GO:0033685 4 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
muscle tissue development GO:0060537 58 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
l glutamate import GO:0051938 2 0.011
cellular response to lipid GO:0071396 201 0.011
peptide hormone secretion GO:0030072 84 0.011
positive regulation of transferase activity GO:0051347 81 0.011
peptide transport GO:0015833 97 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.011
locomotor rhythm GO:0045475 1 0.011
ras protein signal transduction GO:0007265 29 0.011
apoptotic process GO:0006915 381 0.011
small gtpase mediated signal transduction GO:0007264 36 0.010
axon development GO:0061564 96 0.010
rhythmic behavior GO:0007622 24 0.010
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.010
gastric motility GO:0035482 3 0.010
cell cycle GO:0007049 101 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
response to amine GO:0014075 46 0.010
response to estrogen GO:0043627 232 0.010

Hcn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.027
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.022
retinal disease DOID:5679 0 0.017
retinal degeneration DOID:8466 0 0.016
retinitis pigmentosa DOID:10584 0 0.016