Rattus norvegicus

18 known processes

Hcrtr2

hypocretin (orexin) receptor 2

Hcrtr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.377
cytosolic calcium ion homeostasis GO:0051480 140 0.362
Rat
feeding behavior GO:0007631 53 0.328
chemical homeostasis GO:0048878 292 0.320
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.312
synaptic transmission gabaergic GO:0051932 22 0.283
Rat
cellular response to endogenous stimulus GO:0071495 377 0.270
inorganic ion transmembrane transport GO:0098660 229 0.258
positive regulation of phosphate metabolic process GO:0045937 262 0.241
calcium ion homeostasis GO:0055074 162 0.229
Rat
response to peptide hormone GO:0043434 278 0.221
Rat
cellular response to hormone stimulus GO:0032870 247 0.213
heart contraction GO:0060047 57 0.213
Rat
transcription dna templated GO:0006351 377 0.205
carbohydrate metabolic process GO:0005975 130 0.205
positive regulation of signaling GO:0023056 270 0.204
Rat
cellular response to organic cyclic compound GO:0071407 202 0.203
inorganic cation transmembrane transport GO:0098662 202 0.199
regulation of ion transport GO:0043269 245 0.197
Rat
response to glucocorticoid GO:0051384 223 0.194
homeostatic process GO:0042592 331 0.191
Rat
lipid biosynthetic process GO:0008610 128 0.177
organic acid metabolic process GO:0006082 292 0.172
ion homeostasis GO:0050801 212 0.172
Rat
reproductive process GO:0022414 372 0.171
Rat
multicellular organismal reproductive process GO:0048609 233 0.170
Rat
cation transport GO:0006812 382 0.168
Rat
secretion GO:0046903 307 0.167
Rat
hormone secretion GO:0046879 115 0.166
Rat
cation homeostasis GO:0055080 195 0.165
Rat
steroid metabolic process GO:0008202 73 0.163
regulation of cellular component movement GO:0051270 150 0.160
Rat
positive regulation of cell communication GO:0010647 271 0.160
Rat
positive regulation of response to stimulus GO:0048584 285 0.160
Rat
multi organism reproductive process GO:0044703 262 0.159
Rat
transmembrane transport GO:0055085 412 0.158
hormone transport GO:0009914 121 0.158
Rat
regulation of phosphorylation GO:0042325 248 0.155
response to peptide GO:1901652 292 0.154
Rat
eating behavior GO:0042755 21 0.154
Rat
multi multicellular organism process GO:0044706 138 0.153
Rat
response to estradiol GO:0032355 164 0.152
Rat
phenol containing compound metabolic process GO:0018958 30 0.150
Rat
regulation of catalytic activity GO:0050790 304 0.149
positive regulation of developmental process GO:0051094 283 0.148
ion transmembrane transport GO:0034220 365 0.145
cation transmembrane transport GO:0098655 263 0.145
regulation of lipid metabolic process GO:0019216 68 0.143
cellular ion homeostasis GO:0006873 184 0.143
Rat
regulation of secretion GO:0051046 224 0.143
Rat
regulation of cellular localization GO:0060341 263 0.139
Rat
cellular metal ion homeostasis GO:0006875 172 0.137
Rat
cellular cation homeostasis GO:0030003 180 0.135
Rat
regulation of rna biosynthetic process GO:2001141 381 0.134
cellular ketone metabolic process GO:0042180 51 0.134
regulation of nucleic acid templated transcription GO:1903506 380 0.133
lipid metabolic process GO:0006629 283 0.128
cellular response to peptide hormone stimulus GO:0071375 120 0.126
oxoacid metabolic process GO:0043436 290 0.126
regulation of transcription dna templated GO:0006355 374 0.125
regulation of membrane potential GO:0042391 110 0.124
Rat
neurological system process GO:0050877 219 0.124
Rat
metal ion transport GO:0030001 289 0.123
organic hydroxy compound metabolic process GO:1901615 115 0.122
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.117
response to estrogen GO:0043627 232 0.117
Rat
amine metabolic process GO:0009308 38 0.117
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.115
protein phosphorylation GO:0006468 345 0.113
sodium ion transmembrane transport GO:0035725 67 0.112
regulation of anatomical structure size GO:0090066 135 0.109
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.109
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.107
Rat
alcohol metabolic process GO:0006066 77 0.106
regulation of secretion by cell GO:1903530 208 0.102
Rat
nitrogen compound transport GO:0071705 229 0.101
Rat
regulation of blood circulation GO:1903522 110 0.101
Rat
regulation of phosphate metabolic process GO:0019220 349 0.098
regulation of tube size GO:0035150 89 0.097
Rat
cellular calcium ion homeostasis GO:0006874 160 0.096
Rat
carboxylic acid transport GO:0046942 115 0.095
Rat
cellular response to lipid GO:0071396 201 0.095
positive regulation of protein phosphorylation GO:0001934 135 0.094
response to corticosteroid GO:0031960 235 0.093
hormone metabolic process GO:0042445 69 0.092
regulation of hormone levels GO:0010817 187 0.090
Rat
nucleic acid templated transcription GO:0097659 379 0.089
positive regulation of phosphorus metabolic process GO:0010562 262 0.088
intracellular signal transduction GO:0035556 314 0.086
Rat
response to alkaloid GO:0043279 132 0.085
Rat
regulation of calcium ion transport GO:0051924 77 0.085
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.084
cellular divalent inorganic cation homeostasis GO:0072503 162 0.083
Rat
circulatory system process GO:0003013 183 0.083
Rat
regulation of saliva secretion GO:0046877 3 0.082
Rat
steroid biosynthetic process GO:0006694 48 0.082
cellular response to oxygen containing compound GO:1901701 386 0.082
rna biosynthetic process GO:0032774 380 0.081
positive regulation of epithelial cell proliferation GO:0050679 32 0.081
Rat
heart process GO:0003015 57 0.081
Rat
positive regulation of phosphorylation GO:0042327 177 0.080
regulation of muscle system process GO:0090257 79 0.079
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.078
peptidyl tyrosine modification GO:0018212 72 0.078
sensory perception GO:0007600 101 0.077
Rat
positive regulation of blood circulation GO:1903524 65 0.076
Rat
carboxylic acid metabolic process GO:0019752 289 0.076
positive regulation of transport GO:0051050 245 0.076
Rat
positive regulation of molecular function GO:0044093 230 0.076
sexual reproduction GO:0019953 148 0.073
Rat
regulation of protein modification process GO:0031399 194 0.073
peptide secretion GO:0002790 86 0.073
Rat
response to ethanol GO:0045471 162 0.070
Rat
learning or memory GO:0007611 90 0.070
Rat
positive regulation of protein modification process GO:0031401 142 0.069
cellular amine metabolic process GO:0044106 38 0.069
Rat
positive regulation of biosynthetic process GO:0009891 319 0.068
regulation of rna metabolic process GO:0051252 391 0.068
cellular chemical homeostasis GO:0055082 247 0.068
Rat
halogenated hydrocarbon metabolic process GO:0042197 4 0.068
regulation of metal ion transport GO:0010959 118 0.066
olfactory learning GO:0008355 1 0.066
regulation of molecular function GO:0065009 398 0.066
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.065
Mouse
multicellular organism reproduction GO:0032504 233 0.065
Rat
negative regulation of amine transport GO:0051953 24 0.063
Rat
androgen metabolic process GO:0008209 14 0.063
positive regulation of secretion by cell GO:1903532 128 0.063
Rat
cellular amino acid metabolic process GO:0006520 107 0.062
regulation of feeding behavior GO:0060259 14 0.062
Rat
positive regulation of saliva secretion GO:0046878 3 0.062
Rat
chlorinated hydrocarbon metabolic process GO:0042196 4 0.062
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.061
cellular response to organonitrogen compound GO:0071417 197 0.061
peptidyl amino acid modification GO:0018193 126 0.061
head development GO:0060322 247 0.060
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.060
regulation of signal transduction GO:0009966 318 0.059
anion transport GO:0006820 178 0.059
Rat
neuropeptide signaling pathway GO:0007218 29 0.058
rna metabolic process GO:0016070 406 0.058
forebrain development GO:0030900 98 0.057
regulation of locomotion GO:0040012 148 0.057
Rat
negative regulation of ion transport GO:0043271 51 0.057
Rat
cellular lipid metabolic process GO:0044255 208 0.057
regulation of protein phosphorylation GO:0001932 183 0.057
response to mechanical stimulus GO:0009612 134 0.057
Rat
signal transduction by phosphorylation GO:0023014 144 0.056
Rat
signal release GO:0023061 145 0.056
Rat
female pregnancy GO:0007565 122 0.055
organophosphate biosynthetic process GO:0090407 143 0.055
cellular component assembly GO:0022607 360 0.055
Rat
positive regulation of hormone secretion GO:0046887 65 0.055
Rat
memory GO:0007613 54 0.054
Rat
positive regulation of secretion GO:0051047 140 0.054
Rat
muscle system process GO:0003012 115 0.054
Rat
sequestering of metal ion GO:0051238 9 0.054
protein localization GO:0008104 191 0.053
positive regulation of transferase activity GO:0051347 81 0.053
regulation of homeostatic process GO:0032844 101 0.053
Rat
organophosphate metabolic process GO:0019637 370 0.053
single organism behavior GO:0044708 130 0.052
Rat
peptide transport GO:0015833 97 0.052
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.052
macromolecule localization GO:0033036 252 0.049
regulation of cellular protein metabolic process GO:0032268 267 0.049
positive regulation of cellular protein metabolic process GO:0032270 167 0.049
synaptic vesicle amine transport GO:0015842 3 0.049
membrane hyperpolarization GO:0060081 11 0.048
positive regulation of signal transduction GO:0009967 175 0.048
positive regulation of protein metabolic process GO:0051247 178 0.047
positive regulation of rna metabolic process GO:0051254 203 0.047
neuron neuron synaptic transmission GO:0007270 60 0.046
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.046
positive regulation of multicellular organismal process GO:0051240 387 0.046
Rat
blood circulation GO:0008015 183 0.046
Rat
regulation of multicellular organismal development GO:2000026 376 0.046
neuron development GO:0048666 286 0.046
cell projection organization GO:0030030 302 0.045
metal ion homeostasis GO:0055065 186 0.045
Rat
circadian rhythm GO:0007623 88 0.045
cellular carbohydrate metabolic process GO:0044262 72 0.045
regulation of peptide transport GO:0090087 87 0.045
Rat
neuron projection development GO:0031175 273 0.045
cellular response to alcohol GO:0097306 87 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
maintenance of location GO:0051235 17 0.045
cellular homeostasis GO:0019725 252 0.044
Rat
regulation of kinase activity GO:0043549 117 0.044
regulation of cell proliferation GO:0042127 359 0.044
Rat
phasic smooth muscle contraction GO:0014821 3 0.044
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
regulation of system process GO:0044057 208 0.043
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.043
cellular response to steroid hormone stimulus GO:0071383 93 0.042
neuronal action potential GO:0019228 35 0.042
sequestering of calcium ion GO:0051208 8 0.042
negative regulation of signaling GO:0023057 157 0.042
Rat
regeneration GO:0031099 163 0.042
choline transport GO:0015871 4 0.042
regulation of cell motility GO:2000145 131 0.042
Rat
tube development GO:0035295 89 0.042
small molecule biosynthetic process GO:0044283 124 0.041
positive regulation of nervous system development GO:0051962 178 0.041
response to temperature stimulus GO:0009266 94 0.040
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.040
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.040
negative regulation of homeostatic process GO:0032845 47 0.040
single organism carbohydrate metabolic process GO:0044723 118 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
negative regulation of secretion GO:0051048 82 0.039
Rat
response to nutrient levels GO:0031667 370 0.039
regulation of action potential GO:0098900 14 0.038
Rat
oxidation reduction process GO:0055114 304 0.038
regulation of nervous system development GO:0051960 264 0.038
endoplasmic reticulum to cytosol transport GO:1903513 4 0.037
response to mineralocorticoid GO:0051385 49 0.037
single organism reproductive process GO:0044702 297 0.037
Rat
potassium ion transport GO:0006813 97 0.037
positive regulation of intracellular signal transduction GO:1902533 138 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.037
brain development GO:0007420 247 0.036
cell cell signaling GO:0007267 335 0.036
Rat
cellular response to peptide GO:1901653 133 0.036
hormone biosynthetic process GO:0042446 25 0.036
negative regulation of neuron death GO:1901215 69 0.036
response to starvation GO:0042594 59 0.036
negative regulation of hormone secretion GO:0046888 46 0.035
Rat
regulation of synaptic transmission GO:0050804 141 0.035
Rat
regulation of protein metabolic process GO:0051246 289 0.035
regulation of protein kinase activity GO:0045859 105 0.035
response to inorganic substance GO:0010035 377 0.035
Rat
sodium ion transport GO:0006814 82 0.035
defense response GO:0006952 194 0.035
Rat
mapk cascade GO:0000165 140 0.034
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.034
positive regulation of kinase activity GO:0033674 77 0.034
calcium ion transport into cytosol GO:0060402 38 0.034
gland development GO:0048732 155 0.034
response to testosterone GO:0033574 55 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
urinary tract smooth muscle contraction GO:0014848 4 0.034
Rat
phospholipid metabolic process GO:0006644 61 0.033
cellular response to ketone GO:1901655 51 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
behavior GO:0007610 205 0.033
negative regulation of gene expression GO:0010629 199 0.033
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
negative regulation of transport GO:0051051 136 0.032
Rat
regulation of transferase activity GO:0051338 123 0.032
diterpenoid metabolic process GO:0016101 33 0.032
catecholamine metabolic process GO:0006584 19 0.031
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.031
regulation of leukocyte activation GO:0002694 45 0.031
Rat
regulation of blood vessel size GO:0050880 89 0.031
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.031
l glutamate import GO:0051938 2 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
Rat
response to herbicide GO:0009635 16 0.031
regulation of peptide hormone secretion GO:0090276 80 0.031
Rat
response to radiation GO:0009314 137 0.030
adult behavior GO:0030534 16 0.030
negative regulation of glutamate secretion GO:0014050 9 0.030
Rat
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
Rat
positive regulation of cell motility GO:2000147 97 0.030
Rat
regulation of behavior GO:0050795 61 0.030
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
vascular process in circulatory system GO:0003018 96 0.029
Rat
organic acid transport GO:0015849 116 0.029
Rat
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.029
monovalent inorganic cation transport GO:0015672 172 0.029
regulation of cell differentiation GO:0045595 320 0.029
cell motility GO:0048870 202 0.029
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.029
Rat
response to cocaine GO:0042220 39 0.029
Rat
response to vitamin e GO:0033197 24 0.029
central nervous system development GO:0007417 311 0.029
response to acid chemical GO:0001101 222 0.029
Rat
cellular response to insulin stimulus GO:0032869 81 0.029
regulation of calcium ion transport into cytosol GO:0010522 25 0.028
regulation of blood pressure GO:0008217 83 0.028
Rat
response to ketone GO:1901654 182 0.028
Rat
negative regulation of biosynthetic process GO:0009890 168 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
regulation of neuron differentiation GO:0045664 208 0.028
regulation of synaptic transmission glutamatergic GO:0051966 26 0.028
Rat
cellular protein localization GO:0034613 122 0.027
alcohol biosynthetic process GO:0046165 38 0.027
cognition GO:0050890 92 0.027
Rat
regulation of muscle contraction GO:0006937 53 0.027
Rat
activation of protein kinase activity GO:0032147 47 0.027
calcium ion transport GO:0006816 131 0.027
organic hydroxy compound transport GO:0015850 77 0.027
regulation of cell development GO:0060284 263 0.027
regulation of cell migration GO:0030334 128 0.026
Rat
negative regulation of programmed cell death GO:0043069 183 0.026
Rat
response to oxygen levels GO:0070482 265 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
regulation of jak stat cascade GO:0046425 21 0.026
response to dexamethasone GO:0071548 49 0.026
circadian sleep wake cycle process GO:0022410 21 0.026
glutamate secretion GO:0014047 19 0.025
Rat
chemosensory behavior GO:0007635 2 0.025
regulation of epithelial cell proliferation GO:0050678 49 0.025
Rat
protein transport GO:0015031 132 0.025
telencephalon development GO:0021537 62 0.025
response to monosaccharide GO:0034284 159 0.025
camp biosynthetic process GO:0006171 47 0.025
rhythmic behavior GO:0007622 24 0.025
parturition GO:0007567 10 0.025
response to mercury ion GO:0046689 15 0.025
camp metabolic process GO:0046058 63 0.025
positive regulation of protein kinase activity GO:0045860 73 0.025
ossification GO:0001503 70 0.025
Rat
aging GO:0007568 241 0.024
Rat
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.024
growth GO:0040007 165 0.024
saliva secretion GO:0046541 3 0.024
Rat
response to nicotine GO:0035094 51 0.024
Rat
isoprenoid metabolic process GO:0006720 45 0.024
regulation of peptide secretion GO:0002791 82 0.024
Rat
cellular amino acid biosynthetic process GO:0008652 32 0.024
positive regulation of peptide hormone secretion GO:0090277 50 0.023
Rat
single organism catabolic process GO:0044712 283 0.023
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.023
learning GO:0007612 33 0.023
Rat
circadian sleep wake cycle GO:0042745 23 0.023
cellular response to corticosteroid stimulus GO:0071384 69 0.023
digestive system process GO:0022600 24 0.023
Rat
androgen biosynthetic process GO:0006702 10 0.023
response to cytokine GO:0034097 215 0.023
micturition GO:0060073 4 0.023
Rat
positive regulation of catalytic activity GO:0043085 184 0.023
glycerolipid metabolic process GO:0046486 67 0.022
regulation of neurological system process GO:0031644 43 0.022
Rat
regulation of intracellular transport GO:0032386 65 0.022
progesterone biosynthetic process GO:0006701 3 0.022
regulation of hormone secretion GO:0046883 106 0.022
Rat
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.022
positive regulation of heart rate GO:0010460 9 0.022
Rat
lipid catabolic process GO:0016042 46 0.022
positive regulation of camp biosynthetic process GO:0030819 28 0.022
anion transmembrane transport GO:0098656 77 0.022
organic hydroxy compound biosynthetic process GO:1901617 51 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
negative regulation of cell death GO:0060548 229 0.022
Rat
limbic system development GO:0021761 38 0.022
multicellular organismal signaling GO:0035637 44 0.022
muscle contraction GO:0006936 88 0.021
Rat
regulation of heart contraction GO:0008016 48 0.021
Rat
release of sequestered calcium ion into cytosol GO:0051209 25 0.021
ensheathment of neurons GO:0007272 40 0.021
embryonic skeletal system development GO:0048706 3 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
positive regulation of jak stat cascade GO:0046427 19 0.021
divalent metal ion transport GO:0070838 132 0.021
negative regulation of metabolic process GO:0009892 331 0.021
actin filament based process GO:0030029 86 0.021
Rat
regulation of response to external stimulus GO:0032101 106 0.021
Rat
positive regulation of immune system process GO:0002684 90 0.021
Rat
operant conditioning GO:0035106 4 0.021
Rat
immune system process GO:0002376 204 0.021
Rat
regulation of synaptic transmission gabaergic GO:0032228 17 0.021
Rat
dicarboxylic acid transport GO:0006835 34 0.021
Rat
positive regulation of gene expression GO:0010628 244 0.020
regulation of lipid biosynthetic process GO:0046890 38 0.020
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.020
Rat
epithelial cell proliferation GO:0050673 54 0.020
Rat
positive regulation of nucleotide metabolic process GO:0045981 91 0.020
negative regulation of cell communication GO:0010648 158 0.020
Rat
regulation of nucleotide biosynthetic process GO:0030808 47 0.020
positive regulation of peptide secretion GO:0002793 52 0.020
Rat
cellular macromolecule localization GO:0070727 122 0.020
synaptic transmission glutamatergic GO:0035249 33 0.020
Rat
tissue development GO:0009888 252 0.020
vasoconstriction GO:0042310 54 0.020
Rat
positive regulation of mapk cascade GO:0043410 92 0.020
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.020
regulation of smooth muscle cell migration GO:0014910 36 0.020
Rat
vasodilation GO:0042311 44 0.020
regulation of transmembrane transport GO:0034762 122 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.019
protein complex subunit organization GO:0071822 302 0.019
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.019
response to activity GO:0014823 73 0.019
regulation of carbohydrate metabolic process GO:0006109 41 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
terpenoid metabolic process GO:0006721 37 0.019
regulation of smooth muscle contraction GO:0006940 29 0.019
Rat
circadian behavior GO:0048512 24 0.019
organic anion transport GO:0015711 132 0.019
Rat
regulation of camp biosynthetic process GO:0030817 38 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
Rat
positive regulation of growth GO:0045927 55 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
Rat
rhythmic process GO:0048511 156 0.019
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.019
establishment of protein localization GO:0045184 141 0.019
regulation of ion homeostasis GO:2000021 63 0.019
Rat
regulation of sequestering of calcium ion GO:0051282 26 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
regulation of cardiac muscle contraction GO:0055117 17 0.018
cell projection morphogenesis GO:0048858 123 0.018
jak stat cascade GO:0007259 26 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of neuron death GO:1901214 115 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
Rat
regulation of amino acid transport GO:0051955 25 0.018
Rat
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of cell activation GO:0050865 50 0.018
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
gamete generation GO:0007276 124 0.018
urinary bladder smooth muscle contraction GO:0014832 4 0.018
Rat
negative regulation of rna metabolic process GO:0051253 123 0.018
regulation of ossification GO:0030278 32 0.018
Rat
regulation of ion transmembrane transport GO:0034765 121 0.017
reproduction GO:0000003 245 0.017
Rat
amide transport GO:0042886 105 0.017
Rat
dibenzo p dioxin metabolic process GO:0018894 10 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
action potential GO:0001508 54 0.017
Rat
nucleotide metabolic process GO:0009117 279 0.017
organ regeneration GO:0031100 101 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of heart contraction GO:0045823 15 0.017
Rat
response to axon injury GO:0048678 59 0.017
regulation of neurotransmitter levels GO:0001505 42 0.017
cellular hormone metabolic process GO:0034754 49 0.017
response to electrical stimulus GO:0051602 56 0.017
Rat
spermatogenesis GO:0007283 99 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
serotonin receptor signaling pathway GO:0007210 10 0.017
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.017
response to decreased oxygen levels GO:0036293 237 0.017
heart morphogenesis GO:0003007 3 0.017
dopamine secretion GO:0014046 15 0.017
regulation of immune system process GO:0002682 123 0.017
Rat
carbohydrate biosynthetic process GO:0016051 42 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
multicellular organism growth GO:0035264 1 0.016
immune response GO:0006955 104 0.016
membrane organization GO:0061024 94 0.016
camera type eye morphogenesis GO:0048593 2 0.016
negative regulation of amino acid transport GO:0051956 13 0.016
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
smooth muscle contraction GO:0006939 37 0.016
Rat
response to light stimulus GO:0009416 52 0.016
cytosolic calcium ion transport GO:0060401 39 0.016
testosterone biosynthetic process GO:0061370 5 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
Rat
calcium mediated signaling GO:0019722 23 0.016
regulation of growth GO:0040008 105 0.016
response to nutrient GO:0007584 248 0.016
inorganic anion transport GO:0015698 41 0.016
circadian sleep wake cycle sleep GO:0050802 21 0.016
positive regulation of renin secretion into blood stream GO:1900135 1 0.015
response to ammonium ion GO:0060359 71 0.015
Rat
single organism cellular localization GO:1902580 102 0.015
developmental growth GO:0048589 100 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
positive regulation of locomotion GO:0040017 102 0.015
Rat
monoamine transport GO:0015844 43 0.015
positive regulation of action potential GO:0045760 8 0.015
Rat
negative regulation of molecular function GO:0044092 133 0.015
catecholamine transport GO:0051937 37 0.015
cytoplasmic transport GO:0016482 115 0.015
regulation of hydrolase activity GO:0051336 143 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of cation channel activity GO:2001257 23 0.015
pallium development GO:0021543 42 0.015
appendage morphogenesis GO:0035107 4 0.015
response to glucose GO:0009749 136 0.015
response to carbohydrate GO:0009743 183 0.015
negative regulation of organic acid transport GO:0032891 14 0.015
Rat
acid secretion GO:0046717 48 0.015
Rat
single organism intracellular transport GO:1902582 166 0.015
regulation of heart rate GO:0002027 16 0.015
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
lipid localization GO:0010876 62 0.015
male gamete generation GO:0048232 99 0.015

Hcrtr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
nervous system disease DOID:863 0 0.035
disease of anatomical entity DOID:7 0 0.035
musculoskeletal system disease DOID:17 0 0.027
inherited metabolic disorder DOID:655 0 0.020
congenital adrenal hyperplasia DOID:0050811 0 0.016
lipid metabolism disorder DOID:3146 0 0.016
steroid inherited metabolic disorder DOID:1701 0 0.016