Rattus norvegicus

329 known processes

Hdac2

histone deacetylase 2

Hdac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.527
regulation of transcription dna templated GO:0006355 374 0.367
negative regulation of cellular metabolic process GO:0031324 281 0.343
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.322
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.282
regulation of rna metabolic process GO:0051252 391 0.273
rna metabolic process GO:0016070 406 0.242
regulation of nucleic acid templated transcription GO:1903506 380 0.238
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.203
single organism reproductive process GO:0044702 297 0.199
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.185
transcription from rna polymerase ii promoter GO:0006366 252 0.169
regulation of protein metabolic process GO:0051246 289 0.160
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.152
regulation of rna biosynthetic process GO:2001141 381 0.147
negative regulation of metabolic process GO:0009892 331 0.147
negative regulation of gene expression GO:0010629 199 0.146
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.142
nucleic acid templated transcription GO:0097659 379 0.140
negative regulation of nucleic acid templated transcription GO:1903507 117 0.129
developmental process involved in reproduction GO:0003006 159 0.128
negative regulation of macromolecule metabolic process GO:0010605 260 0.116
negative regulation of biosynthetic process GO:0009890 168 0.113
multicellular organism reproduction GO:0032504 233 0.112
reproductive process GO:0022414 372 0.109
negative regulation of cellular biosynthetic process GO:0031327 161 0.105
rna biosynthetic process GO:0032774 380 0.104
multi multicellular organism process GO:0044706 138 0.101
organelle organization GO:0006996 266 0.093
negative regulation of rna metabolic process GO:0051253 123 0.090
multicellular organismal reproductive process GO:0048609 233 0.090
multi organism reproductive process GO:0044703 262 0.089
single organism organelle organization GO:1902589 180 0.087
positive regulation of biosynthetic process GO:0009891 319 0.077
reproductive system development GO:0061458 128 0.073
hemidesmosome assembly GO:0031581 1 0.071
regulation of signal transduction GO:0009966 318 0.071
reproduction GO:0000003 245 0.070
circadian regulation of gene expression GO:0032922 3 0.066
negative regulation of rna biosynthetic process GO:1902679 118 0.066
positive regulation of protein dephosphorylation GO:0035307 4 0.066
cellular component movement GO:0006928 248 0.061
gamete generation GO:0007276 124 0.060
cell migration GO:0016477 197 0.059
chromosome condensation GO:0030261 3 0.058
regulation of cell migration GO:0030334 128 0.058
photoperiodism GO:0009648 4 0.055
development of primary sexual characteristics GO:0045137 107 0.051
sexual reproduction GO:0019953 148 0.051
positive regulation of response to stimulus GO:0048584 285 0.049
cell motility GO:0048870 202 0.048
cellular component biogenesis GO:0044085 368 0.047
ncrna processing GO:0034470 3 0.046
protein complex biogenesis GO:0070271 263 0.046
single organism carbohydrate metabolic process GO:0044723 118 0.046
regulation of cell proliferation GO:0042127 359 0.044
gonad development GO:0008406 104 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
locomotion GO:0040011 237 0.044
response to extracellular stimulus GO:0009991 380 0.044
protein complex subunit organization GO:0071822 302 0.042
macromolecule localization GO:0033036 252 0.042
protein localization to chromosome centromeric region GO:0071459 1 0.042
intracellular transport GO:0046907 185 0.041
positive regulation of cellular protein metabolic process GO:0032270 167 0.040
tissue development GO:0009888 252 0.040
response to temperature stimulus GO:0009266 94 0.040
cellular response to stress GO:0033554 269 0.039
dna packaging GO:0006323 4 0.039
growth GO:0040007 165 0.039
protein localization GO:0008104 191 0.037
regulation of cellular component organization GO:0051128 368 0.036
negative regulation of response to stimulus GO:0048585 155 0.035
central nervous system development GO:0007417 311 0.035
nuclear transport GO:0051169 49 0.034
positive regulation of gene expression GO:0010628 244 0.033
reproductive structure development GO:0048608 128 0.033
response to radiation GO:0009314 137 0.033
cell cycle process GO:0022402 57 0.032
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
cellular glucan metabolic process GO:0006073 23 0.031
negative regulation of cell communication GO:0010648 158 0.030
protein complex assembly GO:0006461 263 0.030
aging GO:0007568 241 0.030
regulation of gene expression epigenetic GO:0040029 10 0.030
response to toxic substance GO:0009636 133 0.029
chromosome segregation GO:0007059 2 0.029
response to nutrient levels GO:0031667 370 0.028
negative regulation of transcription dna templated GO:0045892 116 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
entrainment of circadian clock GO:0009649 3 0.027
behavior GO:0007610 205 0.027
apoptotic process GO:0006915 381 0.026
regulation of cellular localization GO:0060341 263 0.026
defense response GO:0006952 194 0.026
negative regulation of rna splicing GO:0033119 3 0.025
proteolysis GO:0006508 175 0.025
response to biotic stimulus GO:0009607 226 0.025
single organism intracellular transport GO:1902582 166 0.025
carbohydrate metabolic process GO:0005975 130 0.025
sex differentiation GO:0007548 113 0.025
regulation of sister chromatid segregation GO:0033045 1 0.025
regulation of cell differentiation GO:0045595 320 0.024
polysaccharide metabolic process GO:0005976 25 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
cell cycle GO:0007049 101 0.023
learning or memory GO:0007611 90 0.023
glycogen metabolic process GO:0005977 23 0.022
response to other organism GO:0051707 220 0.022
negative regulation of developmental process GO:0051093 125 0.022
mitotic sister chromatid separation GO:0051306 1 0.022
embryo development GO:0009790 49 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
regulation of chromosome segregation GO:0051983 1 0.022
cellular component morphogenesis GO:0032989 155 0.021
negative regulation of signaling GO:0023057 157 0.021
chemosensory behavior GO:0007635 2 0.021
cell cell signaling GO:0007267 335 0.021
catabolic process GO:0009056 351 0.020
dna metabolic process GO:0006259 96 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
cellular macromolecule localization GO:0070727 122 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of cell projection organization GO:0031344 175 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of neuron differentiation GO:0045664 208 0.020
cellular component assembly GO:0022607 360 0.019
response to ethanol GO:0045471 162 0.019
spermatogenesis GO:0007283 99 0.019
cytoplasmic transport GO:0016482 115 0.018
anterior posterior pattern specification GO:0009952 1 0.018
cellular catabolic process GO:0044248 295 0.018
cellular ion homeostasis GO:0006873 184 0.017
cell morphogenesis GO:0000902 142 0.017
cellular chemical homeostasis GO:0055082 247 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
macromolecular complex assembly GO:0065003 273 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
eye morphogenesis GO:0048592 4 0.017
response to inorganic substance GO:0010035 377 0.016
covalent chromatin modification GO:0016569 30 0.016
ncrna metabolic process GO:0034660 8 0.016
regeneration GO:0031099 163 0.016
response to cytokine GO:0034097 215 0.016
male gamete generation GO:0048232 99 0.016
oxidation reduction process GO:0055114 304 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of apoptotic process GO:0042981 335 0.016
regulation of programmed cell death GO:0043067 341 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
response to starvation GO:0042594 59 0.016
dephosphorylation GO:0016311 98 0.016
regulation of growth GO:0040008 105 0.015
neuron development GO:0048666 286 0.015
chemical homeostasis GO:0048878 292 0.015
negative regulation of signal transduction GO:0009968 83 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
female gonad development GO:0008585 53 0.015
trna metabolic process GO:0006399 4 0.015
axis specification GO:0009798 4 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
taxis GO:0042330 67 0.015
posttranscriptional regulation of gene expression GO:0010608 37 0.015
immune response GO:0006955 104 0.015
positive regulation of neurogenesis GO:0050769 165 0.014
regulation of nucleocytoplasmic transport GO:0046822 28 0.014
response to acid chemical GO:0001101 222 0.014
olfactory learning GO:0008355 1 0.014
homeostatic process GO:0042592 331 0.014
translation GO:0006412 35 0.014
spindle organization GO:0007051 2 0.014
response to peptide hormone GO:0043434 278 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
regulation of intracellular transport GO:0032386 65 0.013
cellular polysaccharide metabolic process GO:0044264 23 0.013
positive regulation of cell communication GO:0010647 271 0.013
regulation of catalytic activity GO:0050790 304 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
axon development GO:0061564 96 0.013
response to monosaccharide GO:0034284 159 0.013
protein localization to organelle GO:0033365 57 0.013
response to bacterium GO:0009617 200 0.013
regulation of cellular component movement GO:0051270 150 0.013
neurological system process GO:0050877 219 0.012
microtubule based process GO:0007017 36 0.012
localization of cell GO:0051674 202 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
cellular homeostasis GO:0019725 252 0.012
response to light stimulus GO:0009416 52 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
circadian rhythm GO:0007623 88 0.012
nitrogen compound transport GO:0071705 229 0.012
protein localization to chromosome GO:0034502 1 0.012
rna processing GO:0006396 22 0.012
regulation of defense response GO:0031347 68 0.012
embryonic pattern specification GO:0009880 1 0.012
neuron differentiation GO:0030182 368 0.012
regulation of dna metabolic process GO:0051052 60 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of cell division GO:0051782 1 0.011
rna localization GO:0006403 4 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
response to heat GO:0009408 60 0.011
chromatin modification GO:0016568 33 0.011
regulation of hormone levels GO:0010817 187 0.011
developmental growth GO:0048589 100 0.011
regulation of cell growth GO:0001558 85 0.011
hexose metabolic process GO:0019318 58 0.011
programmed cell death GO:0012501 392 0.011
regulation of translation GO:0006417 27 0.011
regulation of organelle organization GO:0033043 80 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
organic substance catabolic process GO:1901575 316 0.010
ion homeostasis GO:0050801 212 0.010
cell projection organization GO:0030030 302 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
monosaccharide metabolic process GO:0005996 61 0.010
rhythmic process GO:0048511 156 0.010
olfactory behavior GO:0042048 2 0.010
chromosome organization GO:0051276 36 0.010

Hdac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.016
disease of anatomical entity DOID:7 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016
eye disease DOID:5614 0 0.016