Rattus norvegicus

27 known processes

Hdc

histidine decarboxylase

(Aliases: MGC156577)

Hdc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to peptide GO:1901652 292 0.124
homeostatic process GO:0042592 331 0.087
single organism biosynthetic process GO:0044711 342 0.086
response to hexose GO:0009746 144 0.085
fibrinolysis GO:0042730 2 0.083
regulation of response to external stimulus GO:0032101 106 0.081
negative regulation of cell death GO:0060548 229 0.078
cellular component morphogenesis GO:0032989 155 0.077
defense response GO:0006952 194 0.072
regulation of molecular function GO:0065009 398 0.067
cellular component assembly GO:0022607 360 0.065
chemical homeostasis GO:0048878 292 0.065
regulation of programmed cell death GO:0043067 341 0.065
protein complex assembly GO:0006461 263 0.065
cation transport GO:0006812 382 0.064
cellular chemical homeostasis GO:0055082 247 0.060
fatty acid metabolic process GO:0006631 99 0.060
cell projection organization GO:0030030 302 0.059
single organism reproductive process GO:0044702 297 0.058
oxoacid metabolic process GO:0043436 290 0.056
macromolecular complex assembly GO:0065003 273 0.056
regulation of signal transduction GO:0009966 318 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.054
regulation of response to stress GO:0080134 126 0.052
gland development GO:0048732 155 0.051
hepatocyte proliferation GO:0072574 3 0.049
cellular response to endogenous stimulus GO:0071495 377 0.048
Rat
response to wounding GO:0009611 254 0.048
positive regulation of blood coagulation GO:0030194 4 0.047
regeneration GO:0031099 163 0.047
response to carbohydrate GO:0009743 183 0.046
transmembrane transport GO:0055085 412 0.046
multi organism reproductive process GO:0044703 262 0.046
wound healing GO:0042060 122 0.045
response to glucocorticoid GO:0051384 223 0.045
response to extracellular stimulus GO:0009991 380 0.044
multicellular organismal signaling GO:0035637 44 0.044
reproduction GO:0000003 245 0.043
rna biosynthetic process GO:0032774 380 0.043
macromolecular complex subunit organization GO:0043933 339 0.042
cellular homeostasis GO:0019725 252 0.042
response to nutrient levels GO:0031667 370 0.042
carboxylic acid metabolic process GO:0019752 289 0.041
central nervous system development GO:0007417 311 0.041
organic acid metabolic process GO:0006082 292 0.040
positive regulation of response to stimulus GO:0048584 285 0.040
negative regulation of programmed cell death GO:0043069 183 0.040
positive regulation of signal transduction GO:0009967 175 0.040
positive regulation of developmental process GO:0051094 283 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
rna metabolic process GO:0016070 406 0.039
response to monosaccharide GO:0034284 159 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
proteolysis GO:0006508 175 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
regulation of fibrinolysis GO:0051917 2 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
programmed cell death GO:0012501 392 0.037
response to external biotic stimulus GO:0043207 221 0.037
enzyme linked receptor protein signaling pathway GO:0007167 116 0.037
multicellular organism reproduction GO:0032504 233 0.037
regulation of cellular localization GO:0060341 263 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.035
regulation of response to wounding GO:1903034 69 0.035
response to glucose GO:0009749 136 0.034
lipid metabolic process GO:0006629 283 0.034
regulation of cell differentiation GO:0045595 320 0.034
organic hydroxy compound metabolic process GO:1901615 115 0.033
Rat
regulation of phosphate metabolic process GO:0019220 349 0.033
neuronal action potential GO:0019228 35 0.033
lipid transport GO:0006869 61 0.032
positive regulation of secretion by cell GO:1903532 128 0.032
positive regulation of secretion GO:0051047 140 0.032
cellular component biogenesis GO:0044085 368 0.032
organic anion transport GO:0015711 132 0.032
multicellular organismal reproductive process GO:0048609 233 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
immune response GO:0006955 104 0.031
response to cytokine GO:0034097 215 0.031
regulation of ion transport GO:0043269 245 0.031
reproductive process GO:0022414 372 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of catalytic activity GO:0050790 304 0.030
intracellular signal transduction GO:0035556 314 0.030
cation transmembrane transport GO:0098655 263 0.030
neuron death GO:0070997 127 0.030
regulation of apoptotic process GO:0042981 335 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
protein oligomerization GO:0051259 191 0.029
neuron differentiation GO:0030182 368 0.029
response to bacterium GO:0009617 200 0.029
glucose homeostasis GO:0042593 75 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
inorganic ion transmembrane transport GO:0098660 229 0.028
regulation of cellular component organization GO:0051128 368 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
metal ion transport GO:0030001 289 0.028
spermatogenesis GO:0007283 99 0.028
positive regulation of coagulation GO:0050820 5 0.028
neuron projection development GO:0031175 273 0.028
regulation of cell development GO:0060284 263 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
regulation of protein metabolic process GO:0051246 289 0.026
positive regulation of signaling GO:0023056 270 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
protein phosphorylation GO:0006468 345 0.026
head development GO:0060322 247 0.026
positive regulation of nervous system development GO:0051962 178 0.026
response to peptide hormone GO:0043434 278 0.025
regulation of neuron differentiation GO:0045664 208 0.025
regulation of neurogenesis GO:0050767 247 0.025
response to other organism GO:0051707 220 0.025
response to metal ion GO:0010038 253 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
response to corticosteroid GO:0031960 235 0.025
negative regulation of metabolic process GO:0009892 331 0.025
alcohol metabolic process GO:0006066 77 0.025
regulation of nervous system development GO:0051960 264 0.025
ion transmembrane transport GO:0034220 365 0.025
secretion by cell GO:0032940 248 0.024
hemostasis GO:0007599 26 0.024
regulation of phosphorylation GO:0042325 248 0.024
regulation of membrane potential GO:0042391 110 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
small molecule biosynthetic process GO:0044283 124 0.023
regulation of transcription dna templated GO:0006355 374 0.023
regulation of hormone levels GO:0010817 187 0.023
response to biotic stimulus GO:0009607 226 0.023
positive regulation of cell development GO:0010720 176 0.023
cellular amine metabolic process GO:0044106 38 0.023
divalent metal ion transport GO:0070838 132 0.023
mapk cascade GO:0000165 140 0.023
cellular ketone metabolic process GO:0042180 51 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
transmission of nerve impulse GO:0019226 42 0.023
circulatory system process GO:0003013 183 0.023
anion transport GO:0006820 178 0.022
positive regulation of transport GO:0051050 245 0.022
organ regeneration GO:0031100 101 0.022
negative regulation of molecular function GO:0044092 133 0.022
cellular cation homeostasis GO:0030003 180 0.022
response to inorganic substance GO:0010035 377 0.022
negative regulation of fibrinolysis GO:0051918 2 0.022
cell projection morphogenesis GO:0048858 123 0.022
negative regulation of response to external stimulus GO:0032102 37 0.022
plasminogen activation GO:0031639 2 0.022
negative regulation of cell communication GO:0010648 158 0.021
nucleic acid templated transcription GO:0097659 379 0.021
regulation of body fluid levels GO:0050878 90 0.021
carbohydrate homeostasis GO:0033500 75 0.021
negative regulation of response to wounding GO:1903035 23 0.021
positive regulation of cellular component organization GO:0051130 200 0.020
lipid biosynthetic process GO:0008610 128 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
neuron development GO:0048666 286 0.020
hormone metabolic process GO:0042445 69 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
Rat
nitrogen compound transport GO:0071705 229 0.020
Rat
regulation of rna metabolic process GO:0051252 391 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cell motility GO:0048870 202 0.020
cell morphogenesis GO:0000902 142 0.019
cellular response to oxidative stress GO:0034599 76 0.019
protein complex biogenesis GO:0070271 263 0.019
brain development GO:0007420 247 0.019
macromolecule localization GO:0033036 252 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
response to radiation GO:0009314 137 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
Rat
regulation of cell proliferation GO:0042127 359 0.019
cellular component movement GO:0006928 248 0.019
protein complex subunit organization GO:0071822 302 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
negative regulation of signaling GO:0023057 157 0.018
transcription dna templated GO:0006351 377 0.018
amine metabolic process GO:0009308 38 0.018
response to organophosphorus GO:0046683 102 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
epithelial cell proliferation involved in liver morphogenesis GO:0072575 3 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
cellular lipid metabolic process GO:0044255 208 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
Rat
cellular response to hexose stimulus GO:0071331 65 0.017
biological adhesion GO:0022610 110 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
response to insulin GO:0032868 133 0.017
positive regulation of cell communication GO:0010647 271 0.017
regulation of transporter activity GO:0032409 50 0.017
positive regulation of gene expression GO:0010628 244 0.017
regulation of protein modification process GO:0031399 194 0.017
protein homooligomerization GO:0051260 91 0.017
catabolic process GO:0009056 351 0.016
Human Mouse
forebrain development GO:0030900 98 0.016
male gamete generation GO:0048232 99 0.016
apoptotic process GO:0006915 381 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
positive regulation of hemostasis GO:1900048 4 0.016
negative regulation of gene expression GO:0010629 199 0.016
action potential GO:0001508 54 0.016
regulation of secretion by cell GO:1903530 208 0.016
positive regulation of molecular function GO:0044093 230 0.016
cellular response to glucose stimulus GO:0071333 65 0.016
calcium ion transport GO:0006816 131 0.016
cell type specific apoptotic process GO:0097285 134 0.016
developmental growth GO:0048589 100 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
gamete generation GO:0007276 124 0.016
response to decreased oxygen levels GO:0036293 237 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
regulation of cellular response to stress GO:0080135 49 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
response to growth factor GO:0070848 189 0.015
Rat
sexual reproduction GO:0019953 148 0.015
positive regulation of protein modification process GO:0031401 142 0.015
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.015
tissue development GO:0009888 252 0.015
purine containing compound metabolic process GO:0072521 253 0.015
protein processing GO:0016485 68 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
secretion GO:0046903 307 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
Human Mouse Rat
synaptic transmission GO:0007268 235 0.014
Rat
metal ion homeostasis GO:0055065 186 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
response to ketone GO:1901654 182 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
regulation of neuron projection development GO:0010975 161 0.014
cation homeostasis GO:0055080 195 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
axis specification GO:0009798 4 0.014
neurological system process GO:0050877 219 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular response to ketone GO:1901655 51 0.014
tissue regeneration GO:0042246 36 0.014
protein maturation GO:0051604 68 0.014
nucleotide metabolic process GO:0009117 279 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
regulation of anatomical structure size GO:0090066 135 0.013
negative regulation of immune system process GO:0002683 39 0.013
regulation of protein maturation GO:1903317 50 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
dephosphorylation GO:0016311 98 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
liver morphogenesis GO:0072576 3 0.013
coagulation GO:0050817 28 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
Human Mouse
organophosphate metabolic process GO:0019637 370 0.013
oxidation reduction process GO:0055114 304 0.013
cellular ion homeostasis GO:0006873 184 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to vitamin GO:0033273 131 0.013
positive regulation of immunoglobulin production GO:0002639 4 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
cellular amide metabolic process GO:0043603 44 0.013
cellular response to monosaccharide stimulus GO:0071326 67 0.012
organelle assembly GO:0070925 22 0.012
cell part morphogenesis GO:0032990 123 0.012
cofactor metabolic process GO:0051186 95 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
ensheathment of neurons GO:0007272 40 0.012
localization of cell GO:0051674 202 0.012
regulation of immune response GO:0050776 55 0.012
embryonic pattern specification GO:0009880 1 0.012
negative regulation of signal transduction GO:0009968 83 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
regulation of mapk cascade GO:0043408 116 0.012
growth GO:0040007 165 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
carboxylic acid transport GO:0046942 115 0.012
immune effector process GO:0002252 53 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
regulation of transmembrane transport GO:0034762 122 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
calcium ion homeostasis GO:0055074 162 0.012
lipid catabolic process GO:0016042 46 0.011
negative regulation of defense response GO:0031348 19 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
vesicle mediated transport GO:0016192 181 0.011
Rat
divalent inorganic cation transport GO:0072511 134 0.011
protein transport GO:0015031 132 0.011
organelle organization GO:0006996 266 0.011
regulation of transferase activity GO:0051338 123 0.011
cellular response to stress GO:0033554 269 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
negative regulation of cell development GO:0010721 82 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of plasminogen activation GO:0010755 2 0.011
regulation of b cell mediated immunity GO:0002712 2 0.011
intracellular transport GO:0046907 185 0.011
organic substance catabolic process GO:1901575 316 0.011
Human Mouse
maintenance of location GO:0051235 17 0.011
organic acid biosynthetic process GO:0016053 83 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
myelination GO:0042552 39 0.011
regulation of cell projection organization GO:0031344 175 0.011
ion homeostasis GO:0050801 212 0.011
peptide transport GO:0015833 97 0.011
steroid biosynthetic process GO:0006694 48 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
negative regulation of neuron death GO:1901215 69 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of growth GO:0040008 105 0.011
regulation of cell morphogenesis GO:0022604 77 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
regulation of cellular component movement GO:0051270 150 0.010
actin filament based process GO:0030029 86 0.010
regulation of protein transport GO:0051223 68 0.010
peptidyl amino acid modification GO:0018193 126 0.010
fertilization GO:0009566 3 0.010
hormone transport GO:0009914 121 0.010
response to acid chemical GO:0001101 222 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to lipopolysaccharide GO:0032496 191 0.010

Hdc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.047
inherited metabolic disorder DOID:655 0 0.011
disease of anatomical entity DOID:7 0 0.010
musculoskeletal system disease DOID:17 0 0.010