Rattus norvegicus

0 known processes

Higd1a

HIG1 hypoxia inducible domain family, member 1A

(Aliases: Hig1)

Higd1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.214
Mouse
programmed cell death GO:0012501 392 0.137
Mouse
apoptotic process GO:0006915 381 0.129
Mouse
transmembrane transport GO:0055085 412 0.096
catabolic process GO:0009056 351 0.087
proteolysis GO:0006508 175 0.083
intracellular transport GO:0046907 185 0.078
regulation of apoptotic process GO:0042981 335 0.076
Mouse
cell type specific apoptotic process GO:0097285 134 0.074
rna metabolic process GO:0016070 406 0.068
organic acid metabolic process GO:0006082 292 0.060
neuron death GO:0070997 127 0.057
cellular component biogenesis GO:0044085 368 0.053
negative regulation of response to stimulus GO:0048585 155 0.052
Mouse
regulation of cell differentiation GO:0045595 320 0.051
cellular component assembly GO:0022607 360 0.051
protein complex biogenesis GO:0070271 263 0.051
cellular response to stress GO:0033554 269 0.048
Mouse
cation transmembrane transport GO:0098655 263 0.046
response to ethanol GO:0045471 162 0.046
Fly
negative regulation of metabolic process GO:0009892 331 0.046
multi organism reproductive process GO:0044703 262 0.045
carboxylic acid metabolic process GO:0019752 289 0.045
negative regulation of programmed cell death GO:0043069 183 0.042
Mouse
response to inorganic substance GO:0010035 377 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
organic substance catabolic process GO:1901575 316 0.040
cellular catabolic process GO:0044248 295 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
ion transmembrane transport GO:0034220 365 0.037
regulation of molecular function GO:0065009 398 0.037
cellular amine metabolic process GO:0044106 38 0.036
intracellular protein transport GO:0006886 79 0.036
regulation of multicellular organismal development GO:2000026 376 0.034
regulation of cellular component organization GO:0051128 368 0.033
Mouse
response to oxygen levels GO:0070482 265 0.033
Mouse
response to hypoxia GO:0001666 231 0.032
Mouse
modification dependent macromolecule catabolic process GO:0043632 14 0.032
regulation of cell development GO:0060284 263 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
protein transport GO:0015031 132 0.031
mitochondrial transport GO:0006839 19 0.030
central nervous system development GO:0007417 311 0.030
protein oligomerization GO:0051259 191 0.030
macromolecular complex assembly GO:0065003 273 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.029
protein complex subunit organization GO:0071822 302 0.029
regulation of cell proliferation GO:0042127 359 0.029
positive regulation of apoptotic process GO:0043065 154 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
positive regulation of cell death GO:0010942 184 0.028
single organism cellular localization GO:1902580 102 0.028
multicellular organism reproduction GO:0032504 233 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
negative regulation of rna metabolic process GO:0051253 123 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
negative regulation of cell death GO:0060548 229 0.026
Mouse
establishment of protein localization GO:0045184 141 0.026
macromolecule catabolic process GO:0009057 58 0.026
cellular protein localization GO:0034613 122 0.025
brain development GO:0007420 247 0.025
nucleotide biosynthetic process GO:0009165 98 0.025
homeostatic process GO:0042592 331 0.025
regulation of transmembrane transport GO:0034762 122 0.025
neuron differentiation GO:0030182 368 0.024
neuron development GO:0048666 286 0.024
cell projection organization GO:0030030 302 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
aging GO:0007568 241 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
protein transmembrane transport GO:0071806 2 0.022
protein complex assembly GO:0006461 263 0.021
metal ion transport GO:0030001 289 0.021
regulation of neurogenesis GO:0050767 247 0.021
regulation of transcription dna templated GO:0006355 374 0.021
anterior posterior pattern specification GO:0009952 1 0.021
regulation of nervous system development GO:0051960 264 0.020
response to decreased oxygen levels GO:0036293 237 0.020
Mouse
protein targeting GO:0006605 61 0.020
response to corticosteroid GO:0031960 235 0.020
regulation of ion transmembrane transport GO:0034765 121 0.020
epidermal growth factor receptor signaling pathway GO:0007173 23 0.020
sequestering of calcium ion GO:0051208 8 0.020
negative regulation of molecular function GO:0044092 133 0.020
negative regulation of cell communication GO:0010648 158 0.020
Mouse
response to acid chemical GO:0001101 222 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
divalent inorganic cation transport GO:0072511 134 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
amine metabolic process GO:0009308 38 0.019
response to camp GO:0051591 91 0.019
single organism biosynthetic process GO:0044711 342 0.019
oxoacid metabolic process GO:0043436 290 0.019
negative regulation of gene expression GO:0010629 199 0.019
protein localization GO:0008104 191 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
mitochondrion organization GO:0007005 35 0.018
Mouse
cellular homeostasis GO:0019725 252 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.018
single organism reproductive process GO:0044702 297 0.018
modification dependent protein catabolic process GO:0019941 14 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
head development GO:0060322 247 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
regulation of ion transmembrane transporter activity GO:0032412 48 0.017
proteasomal protein catabolic process GO:0010498 8 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
pyridine containing compound metabolic process GO:0072524 32 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of neuron death GO:1901214 115 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
Mouse
positive regulation of programmed cell death GO:0043068 157 0.016
response to nutrient levels GO:0031667 370 0.016
Mouse
organelle organization GO:0006996 266 0.016
Mouse
protein import GO:0017038 37 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cytoplasmic transport GO:0016482 115 0.015
response to gonadotropin GO:0034698 34 0.015
response to organophosphorus GO:0046683 102 0.015
positive regulation of gene expression GO:0010628 244 0.015
positive regulation of cell development GO:0010720 176 0.015
reproductive process GO:0022414 372 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
single organism catabolic process GO:0044712 283 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
response to metal ion GO:0010038 253 0.015
regulation of calcium ion transmembrane transport GO:1903169 18 0.014
response to testosterone GO:0033574 55 0.014
transcription dna templated GO:0006351 377 0.014
cellular ketone metabolic process GO:0042180 51 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
calcium ion transport GO:0006816 131 0.014
nucleic acid templated transcription GO:0097659 379 0.014
rna biosynthetic process GO:0032774 380 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of signal transduction GO:0009966 318 0.014
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.013
regulation of cell growth GO:0001558 85 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
negative regulation of developmental process GO:0051093 125 0.013
reproduction GO:0000003 245 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
response to hexose GO:0009746 144 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
response to ketone GO:1901654 182 0.013
response to glucose GO:0009749 136 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
divalent metal ion transport GO:0070838 132 0.013
synaptic transmission GO:0007268 235 0.013
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of molecular function GO:0044093 230 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.012
chemical homeostasis GO:0048878 292 0.012
response to carbohydrate GO:0009743 183 0.012
positive regulation of developmental process GO:0051094 283 0.012
response to biotic stimulus GO:0009607 226 0.012
cellular response to peptide GO:1901653 133 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.011
regulation of transporter activity GO:0032409 50 0.011
cellular response to lipid GO:0071396 201 0.011
autophagic cell death GO:0048102 4 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
negative regulation of innate immune response GO:0045824 4 0.011
response to extracellular stimulus GO:0009991 380 0.011
Mouse
dendrite development GO:0016358 72 0.011
halogenated hydrocarbon metabolic process GO:0042197 4 0.011
cellular macromolecule localization GO:0070727 122 0.011
neuron projection development GO:0031175 273 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
neuron apoptotic process GO:0051402 88 0.011
cellular response to oxidative stress GO:0034599 76 0.011
carboxylic acid transport GO:0046942 115 0.011
negative regulation of signaling GO:0023057 157 0.011
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of phosphorylation GO:0042325 248 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
single organism intracellular transport GO:1902582 166 0.011
mesoderm development GO:0007498 2 0.011
embryo development GO:0009790 49 0.010
cation transport GO:0006812 382 0.010
male gamete generation GO:0048232 99 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
regulation of metal ion transport GO:0010959 118 0.010
gamete generation GO:0007276 124 0.010
cellular component morphogenesis GO:0032989 155 0.010
regulation of protein metabolic process GO:0051246 289 0.010
carbohydrate homeostasis GO:0033500 75 0.010

Higd1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016