Rattus norvegicus

109 known processes

Hmbs

hydroxymethylbilane synthase

(Aliases: hemC,URO-S,MGC108753,PBG-D,PBGD)

Hmbs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tetrapyrrole biosynthetic process GO:0033014 7 0.828
tetrapyrrole metabolic process GO:0033013 11 0.806
porphyrin containing compound biosynthetic process GO:0006779 6 0.749
porphyrin containing compound metabolic process GO:0006778 8 0.688
organonitrogen compound biosynthetic process GO:1901566 167 0.414
response to inorganic substance GO:0010035 377 0.252
pigment biosynthetic process GO:0046148 4 0.237
cofactor biosynthetic process GO:0051188 28 0.208
response to toxic substance GO:0009636 133 0.165
pteridine containing compound metabolic process GO:0042558 14 0.134
response to cadmium ion GO:0046686 35 0.127
cofactor metabolic process GO:0051186 95 0.124
pigment metabolic process GO:0042440 7 0.108
response to acid chemical GO:0001101 222 0.104
small molecule catabolic process GO:0044282 59 0.091
response to lead ion GO:0010288 33 0.090
heme biosynthetic process GO:0006783 4 0.077
catabolic process GO:0009056 351 0.077
response to decreased oxygen levels GO:0036293 237 0.075
response to metal ion GO:0010038 253 0.072
cellular response to oxidative stress GO:0034599 76 0.067
cellular modified amino acid metabolic process GO:0006575 61 0.066
single organism biosynthetic process GO:0044711 342 0.059
cellular amino acid metabolic process GO:0006520 107 0.053
carbohydrate derivative metabolic process GO:1901135 346 0.050
cellular response to stress GO:0033554 269 0.046
response to oxidative stress GO:0006979 186 0.043
single organism catabolic process GO:0044712 283 0.042
cellular catabolic process GO:0044248 295 0.042
response to hypoxia GO:0001666 231 0.041
organic substance catabolic process GO:1901575 316 0.041
organic acid metabolic process GO:0006082 292 0.041
reproductive process GO:0022414 372 0.040
single organism reproductive process GO:0044702 297 0.038
response to amino acid GO:0043200 75 0.037
single organism organelle organization GO:1902589 180 0.037
intracellular transport GO:0046907 185 0.037
oxoacid metabolic process GO:0043436 290 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
response to hydrogen peroxide GO:0042542 89 0.035
aging GO:0007568 241 0.035
response to herbicide GO:0009635 16 0.034
small molecule biosynthetic process GO:0044283 124 0.032
response to nutrient GO:0007584 248 0.032
organelle organization GO:0006996 266 0.030
response to cobalt ion GO:0032025 12 0.030
sensory organ development GO:0007423 74 0.028
cellular response to reactive oxygen species GO:0034614 55 0.028
response to ketone GO:1901654 182 0.028
regulation of programmed cell death GO:0043067 341 0.027
response to aluminum ion GO:0010044 10 0.026
central nervous system development GO:0007417 311 0.026
defense response GO:0006952 194 0.025
protein targeting GO:0006605 61 0.025
response to estradiol GO:0032355 164 0.025
cellular ketone metabolic process GO:0042180 51 0.025
single organism intracellular transport GO:1902582 166 0.025
nucleotide metabolic process GO:0009117 279 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of signal transduction GO:0009966 318 0.024
response to reactive oxygen species GO:0000302 120 0.024
reproduction GO:0000003 245 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
cellular modified amino acid biosynthetic process GO:0042398 18 0.022
cellular lipid metabolic process GO:0044255 208 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
response to ethanol GO:0045471 162 0.022
cellular response to metal ion GO:0071248 55 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
rna metabolic process GO:0016070 406 0.022
macromolecular complex assembly GO:0065003 273 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
protein complex assembly GO:0006461 263 0.020
protein localization GO:0008104 191 0.020
macromolecule localization GO:0033036 252 0.020
cellular component assembly GO:0022607 360 0.019
establishment of protein localization to organelle GO:0072594 44 0.019
regulation of cellular component organization GO:0051128 368 0.019
ion homeostasis GO:0050801 212 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
regulation of molecular function GO:0065009 398 0.019
cellular protein localization GO:0034613 122 0.019
sulfur compound metabolic process GO:0006790 70 0.018
carbohydrate metabolic process GO:0005975 130 0.018
embryonic pattern specification GO:0009880 1 0.018
serine family amino acid metabolic process GO:0009069 12 0.018
protein complex biogenesis GO:0070271 263 0.018
reproductive structure development GO:0048608 128 0.018
response to peptide GO:1901652 292 0.018
single organism cellular localization GO:1902580 102 0.018
organ regeneration GO:0031100 101 0.017
protein import GO:0017038 37 0.017
nucleoside metabolic process GO:0009116 179 0.017
gonad development GO:0008406 104 0.017
neurological system process GO:0050877 219 0.016
programmed cell death GO:0012501 392 0.016
deoxyribonucleoside triphosphate metabolic process GO:0009200 6 0.016
response to glucocorticoid GO:0051384 223 0.015
intracellular signal transduction GO:0035556 314 0.015
response to platinum ion GO:0070541 4 0.015
protein localization to organelle GO:0033365 57 0.015
rhythmic process GO:0048511 156 0.015
cell migration GO:0016477 197 0.015
mitochondrial transport GO:0006839 19 0.015
regulation of transcription dna templated GO:0006355 374 0.015
response to vitamin GO:0033273 131 0.015
regulation of growth GO:0040008 105 0.015
cellular homeostasis GO:0019725 252 0.014
response to nutrient levels GO:0031667 370 0.014
ovulation cycle GO:0042698 67 0.014
response to peptide hormone GO:0043434 278 0.014
localization of cell GO:0051674 202 0.014
cellular component biogenesis GO:0044085 368 0.014
heterocycle catabolic process GO:0046700 167 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
rna biosynthetic process GO:0032774 380 0.013
regulation of membrane potential GO:0042391 110 0.013
cellular macromolecule localization GO:0070727 122 0.013
response to biotic stimulus GO:0009607 226 0.013
developmental process involved in reproduction GO:0003006 159 0.012
apoptotic process GO:0006915 381 0.012
cell cycle GO:0007049 101 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
growth GO:0040007 165 0.012
response to bacterium GO:0009617 200 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of cellular localization GO:0060341 263 0.012
cellular chemical homeostasis GO:0055082 247 0.012
brain development GO:0007420 247 0.012
sex differentiation GO:0007548 113 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
protein homooligomerization GO:0051260 91 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
camera type eye development GO:0043010 48 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
single organism membrane organization GO:0044802 74 0.012
oxidation reduction process GO:0055114 304 0.012
protein oligomerization GO:0051259 191 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of cell proliferation GO:0042127 359 0.011
steroid biosynthetic process GO:0006694 48 0.011
response to ionizing radiation GO:0010212 59 0.011
neuronal action potential GO:0019228 35 0.011
response to fatty acid GO:0070542 65 0.011
response to external biotic stimulus GO:0043207 221 0.011
aromatic compound catabolic process GO:0019439 168 0.011
protein phosphorylation GO:0006468 345 0.011
response to radiation GO:0009314 137 0.011
synaptic transmission GO:0007268 235 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
response to temperature stimulus GO:0009266 94 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
response to corticosteroid GO:0031960 235 0.011
reproductive system development GO:0061458 128 0.011
establishment of protein localization GO:0045184 141 0.011
response to oxygen levels GO:0070482 265 0.010
hormone metabolic process GO:0042445 69 0.010
positive regulation of synaptic vesicle transport GO:1902805 3 0.010
response to glucose GO:0009749 136 0.010
cytoplasmic transport GO:0016482 115 0.010
cellular cation homeostasis GO:0030003 180 0.010
regulation of nervous system development GO:0051960 264 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
nucleic acid templated transcription GO:0097659 379 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
cellular amine metabolic process GO:0044106 38 0.010
adult locomotory behavior GO:0008344 4 0.010

Hmbs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org