Rattus norvegicus

105 known processes

Hnf1b

HNF1 homeobox B

(Aliases: MGC93549,Tcf2,VHNF1,LF-B3)

Hnf1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.577
cation transmembrane transport GO:0098655 263 0.536
ion transmembrane transport GO:0034220 365 0.478
antibiotic transport GO:0042891 2 0.315
cation transport GO:0006812 382 0.310
aging GO:0007568 241 0.305
inorganic cation transmembrane transport GO:0098662 202 0.280
inorganic ion transmembrane transport GO:0098660 229 0.258
reproductive system development GO:0061458 128 0.195
organic anion transport GO:0015711 132 0.185
sodium ion transport GO:0006814 82 0.157
neuron differentiation GO:0030182 368 0.156
regulation of neurogenesis GO:0050767 247 0.155
nucleic acid templated transcription GO:0097659 379 0.155
metal ion transport GO:0030001 289 0.150
localization of cell GO:0051674 202 0.150
lipid biosynthetic process GO:0008610 128 0.149
regulation of locomotion GO:0040012 148 0.148
neurological system process GO:0050877 219 0.145
blood circulation GO:0008015 183 0.141
response to extracellular stimulus GO:0009991 380 0.138
lipid metabolic process GO:0006629 283 0.133
cellular component movement GO:0006928 248 0.126
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.124
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.124
hepaticobiliary system development GO:0061008 90 0.122
locomotion GO:0040011 237 0.112
tissue development GO:0009888 252 0.103
regulation of rna biosynthetic process GO:2001141 381 0.103
single organism reproductive process GO:0044702 297 0.100
cell motility GO:0048870 202 0.099
glutathione transport GO:0034635 2 0.094
anion transmembrane transport GO:0098656 77 0.093
tripeptide transport GO:0042939 2 0.092
transcription dna templated GO:0006351 377 0.089
response to hexose GO:0009746 144 0.089
oligopeptide transport GO:0006857 4 0.087
response to nutrient GO:0007584 248 0.086
choline transport GO:0015871 4 0.085
single organism catabolic process GO:0044712 283 0.084
cellular component biogenesis GO:0044085 368 0.081
sterol homeostasis GO:0055092 3 0.077
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.077
response to molecule of fungal origin GO:0002238 3 0.076
positive regulation of transport GO:0051050 245 0.076
response to monosaccharide GO:0034284 159 0.075
sodium ion transmembrane transport GO:0035725 67 0.073
cell part morphogenesis GO:0032990 123 0.072
rna biosynthetic process GO:0032774 380 0.070
macromolecular complex assembly GO:0065003 273 0.068
chemical homeostasis GO:0048878 292 0.068
homeostatic process GO:0042592 331 0.067
response to ethanol GO:0045471 162 0.067
circulatory system development GO:0072359 134 0.066
cardiovascular system development GO:0072358 134 0.066
negative regulation of developmental process GO:0051093 125 0.065
cellular response to hormone stimulus GO:0032870 247 0.064
response to molecule of bacterial origin GO:0002237 194 0.064
transcription from rna polymerase ii promoter GO:0006366 252 0.064
cellular component assembly GO:0022607 360 0.063
cell cell signaling GO:0007267 335 0.063
circulatory system process GO:0003013 183 0.062
reproductive structure development GO:0048608 128 0.061
protein complex assembly GO:0006461 263 0.061
response to inorganic substance GO:0010035 377 0.060
g protein coupled receptor signaling pathway GO:0007186 242 0.060
regulation of cellular component movement GO:0051270 150 0.059
response to biotic stimulus GO:0009607 226 0.059
reproductive process GO:0022414 372 0.058
epithelium development GO:0060429 96 0.058
organic acid transport GO:0015849 116 0.058
heart development GO:0007507 72 0.057
cell projection morphogenesis GO:0048858 123 0.057
lipid localization GO:0010876 62 0.057
monocarboxylic acid metabolic process GO:0032787 152 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.055
protein complex biogenesis GO:0070271 263 0.054
monocarboxylic acid transport GO:0015718 52 0.054
developmental process involved in reproduction GO:0003006 159 0.053
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.053
positive regulation of phosphorus metabolic process GO:0010562 262 0.052
regulation of multicellular organismal development GO:2000026 376 0.052
negative regulation of metabolic process GO:0009892 331 0.052
response to other organism GO:0051707 220 0.051
single organism biosynthetic process GO:0044711 342 0.051
protein complex subunit organization GO:0071822 302 0.049
secretion GO:0046903 307 0.048
organic hydroxy compound transport GO:0015850 77 0.048
response to peptide hormone GO:0043434 278 0.048
response to carbohydrate GO:0009743 183 0.047
liver development GO:0001889 90 0.045
cholesterol homeostasis GO:0042632 3 0.045
response to external biotic stimulus GO:0043207 221 0.045
multicellular organismal signaling GO:0035637 44 0.045
calcium ion transport GO:0006816 131 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
nitrogen compound transport GO:0071705 229 0.044
cell projection organization GO:0030030 302 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
response to lipopolysaccharide GO:0032496 191 0.043
neuron development GO:0048666 286 0.042
multi organism reproductive process GO:0044703 262 0.042
positive regulation of ion transport GO:0043270 94 0.042
response to corticosteroid GO:0031960 235 0.042
regulation of cell development GO:0060284 263 0.041
regulation of cell migration GO:0030334 128 0.041
regulation of ion transmembrane transport GO:0034765 121 0.041
protein oligomerization GO:0051259 191 0.040
anion transport GO:0006820 178 0.040
neuron projection development GO:0031175 273 0.040
hepatocyte differentiation GO:0070365 8 0.040
regulation of ion transport GO:0043269 245 0.039
cell migration GO:0016477 197 0.039
cellular response to steroid hormone stimulus GO:0071383 93 0.039
sodium independent organic anion transport GO:0043252 2 0.039
steroid biosynthetic process GO:0006694 48 0.039
positive regulation of transcription dna templated GO:0045893 197 0.038
regulation of cell proliferation GO:0042127 359 0.038
reproduction GO:0000003 245 0.037
behavioral response to nicotine GO:0035095 2 0.037
regulation of lipid biosynthetic process GO:0046890 38 0.037
carboxylic acid metabolic process GO:0019752 289 0.036
response to estradiol GO:0032355 164 0.036
oxidation reduction process GO:0055114 304 0.035
monovalent inorganic cation transport GO:0015672 172 0.035
positive regulation of rna biosynthetic process GO:1902680 197 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
oxoacid metabolic process GO:0043436 290 0.035
negative regulation of innate immune response GO:0045824 4 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
taxis GO:0042330 67 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
vitamin a metabolic process GO:0006776 2 0.033
response to vitamin GO:0033273 131 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
regulation of metal ion transport GO:0010959 118 0.032
response to estrogen GO:0043627 232 0.032
positive regulation of gene expression GO:0010628 244 0.031
modified amino acid transport GO:0072337 12 0.031
regulation of anatomical structure morphogenesis GO:0022603 141 0.031
cellular catabolic process GO:0044248 295 0.031
regulation of epithelial cell proliferation GO:0050678 49 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
synaptic transmission GO:0007268 235 0.030
amino acid transmembrane transport GO:0003333 33 0.030
sex differentiation GO:0007548 113 0.029
amino acid transport GO:0006865 70 0.029
response to hypoxia GO:0001666 231 0.029
regulation of microvillus organization GO:0032530 1 0.028
biological adhesion GO:0022610 110 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
apoptotic process GO:0006915 381 0.028
potassium ion transmembrane transport GO:0071805 71 0.028
glucose homeostasis GO:0042593 75 0.028
positive regulation of molecular function GO:0044093 230 0.028
epithelial cell proliferation GO:0050673 54 0.027
carnitine transport GO:0015879 1 0.027
ion homeostasis GO:0050801 212 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
divalent metal ion transport GO:0070838 132 0.026
positive regulation of cell migration GO:0030335 96 0.026
toxin transport GO:1901998 3 0.026
small molecule biosynthetic process GO:0044283 124 0.026
response to glucocorticoid GO:0051384 223 0.026
carboxylic acid transport GO:0046942 115 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
regulation of growth GO:0040008 105 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
regulation of cell projection organization GO:0031344 175 0.025
lipid storage GO:0019915 1 0.025
axon development GO:0061564 96 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
regulation of stem cell differentiation GO:2000736 2 0.025
hepatocyte proliferation GO:0072574 3 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
response to glucose GO:0009749 136 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
cellular lipid metabolic process GO:0044255 208 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
drug transmembrane transport GO:0006855 13 0.024
lipid transport GO:0006869 61 0.024
activation of protein kinase activity GO:0032147 47 0.024
regulation of cell differentiation GO:0045595 320 0.024
carboxylic acid biosynthetic process GO:0046394 83 0.024
quaternary ammonium group transport GO:0015697 6 0.023
response to bacterium GO:0009617 200 0.023
multicellular organism reproduction GO:0032504 233 0.023
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.023
regulation of cell motility GO:2000145 131 0.023
smooth muscle cell migration GO:0014909 36 0.023
regulation of body fluid levels GO:0050878 90 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
sensory perception GO:0007600 101 0.023
hexose metabolic process GO:0019318 58 0.023
response to peptide GO:1901652 292 0.023
positive regulation of developmental process GO:0051094 283 0.022
neuronal action potential GO:0019228 35 0.022
response to tumor cell GO:0002347 4 0.022
organ morphogenesis GO:0009887 75 0.022
response to heat GO:0009408 60 0.022
secretion by cell GO:0032940 248 0.022
cellular potassium ion transport GO:0071804 72 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.021
regulation of transcription dna templated GO:0006355 374 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cell morphogenesis GO:0000902 142 0.021
regulation of blood pressure GO:0008217 83 0.021
catabolic process GO:0009056 351 0.021
ensheathment of neurons GO:0007272 40 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
single organism intracellular transport GO:1902582 166 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
positive regulation of nervous system development GO:0051962 178 0.020
response to nutrient levels GO:0031667 370 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
response to wounding GO:0009611 254 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
positive regulation of phagocytosis engulfment GO:0060100 4 0.019
sexual reproduction GO:0019953 148 0.019
regulation of hormone levels GO:0010817 187 0.019
hormone mediated signaling pathway GO:0009755 23 0.019
somatostatin receptor signaling pathway GO:0038169 4 0.019
insecticide metabolic process GO:0017143 4 0.019
macromolecule localization GO:0033036 252 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
gonad development GO:0008406 104 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
defense response to gram negative bacterium GO:0050829 3 0.019
organelle organization GO:0006996 266 0.019
regulation of carbohydrate metabolic process GO:0006109 41 0.018
positive regulation of epithelial cell proliferation GO:0050679 32 0.018
cellular amine metabolic process GO:0044106 38 0.018
rna metabolic process GO:0016070 406 0.018
single organism organelle organization GO:1902589 180 0.018
regulation of phagocytosis engulfment GO:0060099 4 0.018
organic substance catabolic process GO:1901575 316 0.018
dendrite morphogenesis GO:0048813 43 0.018
regulation of neuron projection development GO:0010975 161 0.018
transmission of nerve impulse GO:0019226 42 0.018
bile acid and bile salt transport GO:0015721 12 0.018
epithelial cell differentiation GO:0030855 71 0.018
regulation of nervous system development GO:0051960 264 0.018
muscle cell migration GO:0014812 36 0.017
positive regulation of locomotion GO:0040017 102 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
tube development GO:0035295 89 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
regulation of signal transduction GO:0009966 318 0.017
brain development GO:0007420 247 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
ossification GO:0001503 70 0.017
regulation of synaptic transmission GO:0050804 141 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
positive regulation of signaling GO:0023056 270 0.017
action potential GO:0001508 54 0.017
positive regulation of cell development GO:0010720 176 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
carbohydrate homeostasis GO:0033500 75 0.016
negative regulation of gene expression GO:0010629 199 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
neuron projection morphogenesis GO:0048812 122 0.016
cellular chemical homeostasis GO:0055082 247 0.016
negative regulation of cell development GO:0010721 82 0.016
forebrain development GO:0030900 98 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
female pregnancy GO:0007565 122 0.016
alcohol metabolic process GO:0006066 77 0.016
monosaccharide metabolic process GO:0005996 61 0.016
maintenance of location GO:0051235 17 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.016
cellular response to peptide GO:1901653 133 0.016
multicellular organismal water homeostasis GO:0050891 4 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
organophosphate metabolic process GO:0019637 370 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
dendrite development GO:0016358 72 0.016
nucleotide metabolic process GO:0009117 279 0.015
response to toxic substance GO:0009636 133 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
regulation of rna metabolic process GO:0051252 391 0.015
negative regulation of molecular function GO:0044092 133 0.015
negative regulation of response to wounding GO:1903035 23 0.015
regulation of transferase activity GO:0051338 123 0.015
wound healing spreading of cells GO:0044319 2 0.015
drug transport GO:0015893 18 0.015
amine metabolic process GO:0009308 38 0.015
programmed cell death GO:0012501 392 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
regulation of amine transport GO:0051952 54 0.015
regulation of cell growth GO:0001558 85 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
developmental induction GO:0031128 2 0.015
carbohydrate metabolic process GO:0005975 130 0.015
regulation of protein modification process GO:0031399 194 0.015
cellular ketone metabolic process GO:0042180 51 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
cell junction organization GO:0034330 21 0.015
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.015
behavior GO:0007610 205 0.015
glucose metabolic process GO:0006006 52 0.014
regulation of cellular component organization GO:0051128 368 0.014
multi multicellular organism process GO:0044706 138 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
divalent inorganic cation transport GO:0072511 134 0.014
regulation of catalytic activity GO:0050790 304 0.014
potassium ion transport GO:0006813 97 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
regulation of system process GO:0044057 208 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
vitamin d receptor signaling pathway GO:0070561 1 0.014
wound healing GO:0042060 122 0.014
embryo development GO:0009790 49 0.014
defense response GO:0006952 194 0.014
intracellular signal transduction GO:0035556 314 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
cellular amide metabolic process GO:0043603 44 0.014
muscle organ development GO:0007517 50 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
gamete generation GO:0007276 124 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
steroid metabolic process GO:0008202 73 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
sulfur compound transport GO:0072348 8 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
spermatogenesis GO:0007283 99 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of response to external stimulus GO:0032101 106 0.013
dopamine transport GO:0015872 18 0.013
organic acid metabolic process GO:0006082 292 0.013
regulation of smooth muscle cell migration GO:0014910 36 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
positive regulation of cell motility GO:2000147 97 0.013
response to vitamin a GO:0033189 36 0.013
response to metal ion GO:0010038 253 0.013
axon ensheathment GO:0008366 40 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
negative regulation of cell death GO:0060548 229 0.013
cellular component morphogenesis GO:0032989 155 0.012
peptidyl amino acid modification GO:0018193 126 0.012
glycerol transport GO:0015793 2 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of membrane potential GO:0042391 110 0.012
response to decreased oxygen levels GO:0036293 237 0.012
positive regulation of hepatocyte differentiation GO:0070368 2 0.012
positive regulation of amine transport GO:0051954 26 0.012
hormone transport GO:0009914 121 0.012
regeneration GO:0031099 163 0.012
regulation of calcium ion transport GO:0051924 77 0.012
establishment of tissue polarity GO:0007164 2 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
male gamete generation GO:0048232 99 0.012
regulation of sodium ion transport GO:0002028 21 0.012
ameboidal type cell migration GO:0001667 26 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cytoskeleton organization GO:0007010 111 0.012
positive regulation of lipid biosynthetic process GO:0046889 25 0.012
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
immune system process GO:0002376 204 0.012
chromosome segregation GO:0007059 2 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.012
gastrulation GO:0007369 2 0.012
visual learning GO:0008542 8 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of secretion GO:0051046 224 0.012
negative regulation of feeding behavior GO:2000252 8 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
gland development GO:0048732 155 0.012
gliogenesis GO:0042063 93 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
vesicle mediated transport GO:0016192 181 0.012
negative regulation of cellular component organization GO:0051129 83 0.011
amino acid betaine transport GO:0015838 1 0.011
acid secretion GO:0046717 48 0.011
muscle structure development GO:0061061 87 0.011
signal transduction involved in regulation of gene expression GO:0023019 4 0.011
fatty acid metabolic process GO:0006631 99 0.011
monoamine transport GO:0015844 43 0.011
response to insulin GO:0032868 133 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cell growth GO:0016049 104 0.011
cellular response to external stimulus GO:0071496 118 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
chemotaxis GO:0006935 66 0.011
positive regulation of immune system process GO:0002684 90 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
cellular response to glucose stimulus GO:0071333 65 0.010
muscle system process GO:0003012 115 0.010
response to axon injury GO:0048678 59 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
positive regulation of dendrite development GO:1900006 35 0.010
cellular response to alcohol GO:0097306 87 0.010
cellular glucose homeostasis GO:0001678 66 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
response to starvation GO:0042594 59 0.010
acetate ester transport GO:1901374 7 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
myelination GO:0042552 39 0.010
regulation of intracellular transport GO:0032386 65 0.010
sensory perception of pain GO:0019233 73 0.010

Hnf1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.107
respiratory system disease DOID:1579 0 0.107
lower respiratory tract disease DOID:0050161 0 0.107
disease of metabolism DOID:0014667 0 0.031
nervous system disease DOID:863 0 0.022
maturity onset diabetes of the young DOID:0050524 0 0.015
sensory system disease DOID:0050155 0 0.013
inherited metabolic disorder DOID:655 0 0.011