Rattus norvegicus

13 known processes

Hoxb13

homeo box B13

Hoxb13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to hormone stimulus GO:0032870 247 0.305
cellular response to organic cyclic compound GO:0071407 202 0.231
response to inorganic substance GO:0010035 377 0.170
cellular response to endogenous stimulus GO:0071495 377 0.169
cellular response to peptide hormone stimulus GO:0071375 120 0.145
regulation of cellular component organization GO:0051128 368 0.140
response to glucocorticoid GO:0051384 223 0.124
cellular response to peptide GO:1901653 133 0.103
response to hypoxia GO:0001666 231 0.096
protein complex biogenesis GO:0070271 263 0.095
response to acid chemical GO:0001101 222 0.092
regulation of cell proliferation GO:0042127 359 0.089
response to extracellular stimulus GO:0009991 380 0.088
immune system process GO:0002376 204 0.088
cellular response to growth factor stimulus GO:0071363 162 0.081
response to peptide GO:1901652 292 0.081
cellular response to lipid GO:0071396 201 0.080
response to peptide hormone GO:0043434 278 0.076
organic substance catabolic process GO:1901575 316 0.074
regulation of anatomical structure morphogenesis GO:0022603 141 0.074
response to corticosteroid GO:0031960 235 0.073
intracellular signal transduction GO:0035556 314 0.071
protein complex assembly GO:0006461 263 0.071
rna biosynthetic process GO:0032774 380 0.070
nucleic acid templated transcription GO:0097659 379 0.068
negative regulation of metabolic process GO:0009892 331 0.065
macromolecular complex subunit organization GO:0043933 339 0.065
response to nutrient levels GO:0031667 370 0.063
negative regulation of cellular biosynthetic process GO:0031327 161 0.061
response to growth factor GO:0070848 189 0.059
negative regulation of cellular metabolic process GO:0031324 281 0.057
single organism reproductive process GO:0044702 297 0.057
rna metabolic process GO:0016070 406 0.056
cellular component biogenesis GO:0044085 368 0.056
transcription dna templated GO:0006351 377 0.055
regulation of nucleic acid templated transcription GO:1903506 380 0.055
positive regulation of multicellular organismal process GO:0051240 387 0.055
carboxylic acid metabolic process GO:0019752 289 0.054
multicellular organism reproduction GO:0032504 233 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
regulation of anatomical structure size GO:0090066 135 0.053
regulation of immune system process GO:0002682 123 0.053
cellular response to alcohol GO:0097306 87 0.053
cellular response to oxygen containing compound GO:1901701 386 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.053
protein phosphorylation GO:0006468 345 0.052
positive regulation of gene expression GO:0010628 244 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
organic acid metabolic process GO:0006082 292 0.050
cellular component assembly GO:0022607 360 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.049
macromolecular complex assembly GO:0065003 273 0.049
protein complex subunit organization GO:0071822 302 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.048
response to oxygen levels GO:0070482 265 0.048
multi organism reproductive process GO:0044703 262 0.048
positive regulation of phosphorylation GO:0042327 177 0.047
wound healing GO:0042060 122 0.047
oxoacid metabolic process GO:0043436 290 0.046
non canonical wnt signaling pathway GO:0035567 3 0.046
tissue development GO:0009888 252 0.046
defense response GO:0006952 194 0.045
response to cytokine GO:0034097 215 0.045
positive regulation of cell motility GO:2000147 97 0.044
aging GO:0007568 241 0.044
neuron differentiation GO:0030182 368 0.043
multi multicellular organism process GO:0044706 138 0.043
regulation of cell motility GO:2000145 131 0.043
regulation of transcription dna templated GO:0006355 374 0.042
protein oligomerization GO:0051259 191 0.042
response to external biotic stimulus GO:0043207 221 0.042
cellular response to nitrogen compound GO:1901699 210 0.041
cellular amine metabolic process GO:0044106 38 0.041
cell cell signaling GO:0007267 335 0.041
negative regulation of nucleic acid templated transcription GO:1903507 117 0.040
positive regulation of developmental process GO:0051094 283 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
positive regulation of cellular amine metabolic process GO:0033240 3 0.039
cellular ketone metabolic process GO:0042180 51 0.038
reproduction GO:0000003 245 0.038
catabolic process GO:0009056 351 0.037
amine metabolic process GO:0009308 38 0.037
negative regulation of biosynthetic process GO:0009890 168 0.037
circulatory system process GO:0003013 183 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
response to biotic stimulus GO:0009607 226 0.037
response to decreased oxygen levels GO:0036293 237 0.036
negative regulation of cell death GO:0060548 229 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.035
regulation of protein metabolic process GO:0051246 289 0.035
cellular response to stress GO:0033554 269 0.035
response to retinoic acid GO:0032526 63 0.035
positive regulation of locomotion GO:0040017 102 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
regulation of response to stress GO:0080134 126 0.034
biological adhesion GO:0022610 110 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
response to metal ion GO:0010038 253 0.033
positive regulation of cellular component movement GO:0051272 102 0.033
negative regulation of rna metabolic process GO:0051253 123 0.033
response to vitamin GO:0033273 131 0.033
response to other organism GO:0051707 220 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
reproductive process GO:0022414 372 0.031
response to estrogen GO:0043627 232 0.031
response to mechanical stimulus GO:0009612 134 0.031
regulation of molecular function GO:0065009 398 0.031
response to nutrient GO:0007584 248 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
cell projection organization GO:0030030 302 0.030
response to purine containing compound GO:0014074 126 0.030
circulatory system development GO:0072359 134 0.030
Human
regulation of cell differentiation GO:0045595 320 0.030
anion transmembrane transport GO:0098656 77 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
regulation of cell projection organization GO:0031344 175 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
Human Rat
negative regulation of gene expression GO:0010629 199 0.029
developmental process involved in reproduction GO:0003006 159 0.029
regulation of rna metabolic process GO:0051252 391 0.029
cellular response to steroid hormone stimulus GO:0071383 93 0.029
chemical homeostasis GO:0048878 292 0.029
regulation of protein modification process GO:0031399 194 0.028
sexual reproduction GO:0019953 148 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cellular response to insulin stimulus GO:0032869 81 0.027
neurological system process GO:0050877 219 0.027
macromolecule localization GO:0033036 252 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
response to ketone GO:1901654 182 0.026
lipid metabolic process GO:0006629 283 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of blood vessel size GO:0050880 89 0.026
neuron projection development GO:0031175 273 0.026
apoptotic process GO:0006915 381 0.025
cellular catabolic process GO:0044248 295 0.025
negative regulation of transport GO:0051051 136 0.025
single organism catabolic process GO:0044712 283 0.025
regulation of cellular component movement GO:0051270 150 0.025
organelle organization GO:0006996 266 0.024
response to camp GO:0051591 91 0.024
response to nicotine GO:0035094 51 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
negative regulation of cell communication GO:0010648 158 0.024
regulation of locomotion GO:0040012 148 0.024
regulation of system process GO:0044057 208 0.024
central nervous system development GO:0007417 311 0.024
cellular lipid metabolic process GO:0044255 208 0.023
intracellular transport GO:0046907 185 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
response to lipopolysaccharide GO:0032496 191 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
response to wounding GO:0009611 254 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
programmed cell death GO:0012501 392 0.022
synaptic transmission GO:0007268 235 0.022
regulation of signal transduction GO:0009966 318 0.022
regulation of jnk cascade GO:0046328 19 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
regulation of synaptic transmission GO:0050804 141 0.022
innate immune response GO:0045087 35 0.021
regulation of phosphorylation GO:0042325 248 0.021
regulation of lipid metabolic process GO:0019216 68 0.021
blood vessel morphogenesis GO:0048514 58 0.021
Human
regulation of apoptotic process GO:0042981 335 0.021
cardiovascular system development GO:0072358 134 0.021
Human
negative regulation of rna biosynthetic process GO:1902679 118 0.021
locomotion GO:0040011 237 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
response to estradiol GO:0032355 164 0.021
regulation of cell development GO:0060284 263 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
regulation of neuron death GO:1901214 115 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
ovulation cycle process GO:0022602 50 0.020
positive regulation of cell migration GO:0030335 96 0.020
organophosphate metabolic process GO:0019637 370 0.020
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.020
signal transduction by phosphorylation GO:0023014 144 0.019
regulation of tube size GO:0035150 89 0.019
regulation of establishment of planar polarity GO:0090175 2 0.019
cellular response to acid chemical GO:0071229 75 0.019
response to bacterium GO:0009617 200 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
regulation of defense response GO:0031347 68 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
positive regulation of transcription dna templated GO:0045893 197 0.018
proteolysis GO:0006508 175 0.018
lipid biosynthetic process GO:0008610 128 0.018
growth GO:0040007 165 0.018
angiogenesis GO:0001525 53 0.018
Human
cellular homeostasis GO:0019725 252 0.018
regulation of catalytic activity GO:0050790 304 0.018
ion transmembrane transport GO:0034220 365 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
response to oxidative stress GO:0006979 186 0.018
cell adhesion GO:0007155 110 0.018
mapk cascade GO:0000165 140 0.018
vasculature development GO:0001944 70 0.018
Human
metestrus GO:0060210 1 0.017
immune response GO:0006955 104 0.017
single organism organelle organization GO:1902589 180 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
fatty acid metabolic process GO:0006631 99 0.017
neuron development GO:0048666 286 0.017
establishment of tissue polarity GO:0007164 2 0.017
vascular process in circulatory system GO:0003018 96 0.017
regulation of response to external stimulus GO:0032101 106 0.017
small molecule biosynthetic process GO:0044283 124 0.017
cation transport GO:0006812 382 0.017
establishment of planar polarity GO:0001736 1 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
epithelial cell differentiation GO:0030855 71 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
positive regulation of immune system process GO:0002684 90 0.016
regulation of ion transport GO:0043269 245 0.016
gonad development GO:0008406 104 0.016
response to insulin GO:0032868 133 0.016
chromosome segregation GO:0007059 2 0.016
response to toxic substance GO:0009636 133 0.016
spermatogenesis GO:0007283 99 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
blood circulation GO:0008015 183 0.016
response to activity GO:0014823 73 0.016
positive regulation of protein modification process GO:0031401 142 0.016
secretion GO:0046903 307 0.016
vasoconstriction GO:0042310 54 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
regeneration GO:0031099 163 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of programmed cell death GO:0043067 341 0.015
regulation of nervous system development GO:0051960 264 0.015
regulation of blood circulation GO:1903522 110 0.015
response to amino acid GO:0043200 75 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
negative regulation of signaling GO:0023057 157 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
salivary gland morphogenesis GO:0007435 1 0.015
regulation of muscle system process GO:0090257 79 0.015
gamete generation GO:0007276 124 0.015
regulation of cellular response to stress GO:0080135 49 0.014
regulation of transferase activity GO:0051338 123 0.014
ovulation cycle GO:0042698 67 0.014
negative regulation of molecular function GO:0044092 133 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
positive regulation of transferase activity GO:0051347 81 0.014
regulation of inflammatory response GO:0050727 48 0.014
regulation of organelle organization GO:0033043 80 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to organophosphorus GO:0046683 102 0.014
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
regulation of cell migration GO:0030334 128 0.014
jnk cascade GO:0007254 28 0.014
muscle system process GO:0003012 115 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
regulation of epithelial cell proliferation GO:0050678 49 0.014
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.014
organ regeneration GO:0031100 101 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
vesicle mediated transport GO:0016192 181 0.013
regulation of response to wounding GO:1903034 69 0.013
ion homeostasis GO:0050801 212 0.013
response to carbohydrate GO:0009743 183 0.013
cellular response to external stimulus GO:0071496 118 0.013
response to temperature stimulus GO:0009266 94 0.013
positive regulation of blood circulation GO:1903524 65 0.013
regulation of immune response GO:0050776 55 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of body fluid levels GO:0050878 90 0.013
stress activated mapk cascade GO:0051403 35 0.013
regulation of cell projection size GO:0032536 1 0.013
regulation of cellular component size GO:0032535 51 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
defense response to gram positive bacterium GO:0050830 2 0.013
ribonucleotide metabolic process GO:0009259 231 0.012
establishment of protein localization GO:0045184 141 0.012
single organism intracellular transport GO:1902582 166 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular response to metal ion GO:0071248 55 0.012
response to ethanol GO:0045471 162 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
mesoderm development GO:0007498 2 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
rhythmic process GO:0048511 156 0.012
epithelium development GO:0060429 96 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
urogenital system development GO:0001655 78 0.012
regulation of membrane potential GO:0042391 110 0.012
cellular amide metabolic process GO:0043603 44 0.012
cellular response to fluid shear stress GO:0071498 4 0.012
positive regulation of transport GO:0051050 245 0.012
organ formation GO:0048645 3 0.012
brain development GO:0007420 247 0.012
female pregnancy GO:0007565 122 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
male gamete generation GO:0048232 99 0.012
negative regulation of innate immune response GO:0045824 4 0.012
muscle structure development GO:0061061 87 0.012
action potential GO:0001508 54 0.012
localization of cell GO:0051674 202 0.012
reproductive system development GO:0061458 128 0.011
behavior GO:0007610 205 0.011
immune effector process GO:0002252 53 0.011
morphogenesis of a polarized epithelium GO:0001738 1 0.011
positive regulation of response to wounding GO:1903036 34 0.011
response to increased oxygen levels GO:0036296 45 0.011
cellular cation homeostasis GO:0030003 180 0.011
positive regulation of signaling GO:0023056 270 0.011
regulation of cell maturation GO:1903429 3 0.011
cellular component movement GO:0006928 248 0.011
regulation of cell cycle GO:0051726 73 0.011
sex differentiation GO:0007548 113 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.011
intracellular protein transport GO:0006886 79 0.011
regulation of cell activation GO:0050865 50 0.011
anion transport GO:0006820 178 0.011
smooth muscle cell migration GO:0014909 36 0.011
homeostatic process GO:0042592 331 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cellular response to inorganic substance GO:0071241 65 0.011
blood vessel development GO:0001568 69 0.010
Human
single organism biosynthetic process GO:0044711 342 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
regulation of cell adhesion GO:0030155 52 0.010
regulation of actin cytoskeleton organization GO:0032956 30 0.010
regulation of mapk cascade GO:0043408 116 0.010
regulation of neuron differentiation GO:0045664 208 0.010
brain renin angiotensin system GO:0002035 3 0.010
regulation of neuron projection development GO:0010975 161 0.010
axis specification GO:0009798 4 0.010
regulation of embryonic development GO:0045995 2 0.010
regulation of growth GO:0040008 105 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of jnk cascade GO:0046330 13 0.010

Hoxb13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
gastrointestinal system disease DOID:77 0 0.015
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011