Rattus norvegicus

0 known processes

Hoxd3

homeo box D3

(Aliases: Hox4r6)

Hoxd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gene expression GO:0010628 244 0.578
Human
transcription dna templated GO:0006351 377 0.383
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.305
transcription from rna polymerase ii promoter GO:0006366 252 0.270
negative regulation of rna metabolic process GO:0051253 123 0.268
regulation of rna metabolic process GO:0051252 391 0.265
negative regulation of metabolic process GO:0009892 331 0.265
regulation of rna biosynthetic process GO:2001141 381 0.260
regulation of nucleic acid templated transcription GO:1903506 380 0.250
positive regulation of rna metabolic process GO:0051254 203 0.241
regulation of transcription dna templated GO:0006355 374 0.238
programmed cell death GO:0012501 392 0.232
cellular response to oxygen containing compound GO:1901701 386 0.230
negative regulation of neuron differentiation GO:0045665 62 0.228
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.227
positive regulation of rna biosynthetic process GO:1902680 197 0.205
negative regulation of nucleic acid templated transcription GO:1903507 117 0.197
apoptotic process GO:0006915 381 0.192
negative regulation of gene expression GO:0010629 199 0.159
secretion by cell GO:0032940 248 0.157
positive regulation of transcription dna templated GO:0045893 197 0.154
positive regulation of cell death GO:0010942 184 0.129
rna metabolic process GO:0016070 406 0.127
Human
positive regulation of neuron migration GO:2001224 2 0.126
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.123
regulation of neurogenesis GO:0050767 247 0.121
Mouse
tissue development GO:0009888 252 0.120
Mouse
positive regulation of secretion GO:0051047 140 0.118
brain development GO:0007420 247 0.112
nucleic acid templated transcription GO:0097659 379 0.112
Human
negative regulation of transcription dna templated GO:0045892 116 0.111
regulation of apoptotic process GO:0042981 335 0.110
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.110
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.108
rna biosynthetic process GO:0032774 380 0.105
Human
neurological system process GO:0050877 219 0.103
negative regulation of cellular metabolic process GO:0031324 281 0.102
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.098
positive regulation of secretion by cell GO:1903532 128 0.098
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.095
organ morphogenesis GO:0009887 75 0.094
Mouse
ion transmembrane transport GO:0034220 365 0.094
negative regulation of macromolecule metabolic process GO:0010605 260 0.093
negative regulation of cellular biosynthetic process GO:0031327 161 0.088
motor neuron axon guidance GO:0008045 1 0.087
cellular ion homeostasis GO:0006873 184 0.086
positive regulation of nucleic acid templated transcription GO:1903508 197 0.085
head development GO:0060322 247 0.085
cellular chemical homeostasis GO:0055082 247 0.084
sensory organ development GO:0007423 74 0.083
regulation of axonogenesis GO:0050770 37 0.079
positive regulation of apoptotic process GO:0043065 154 0.077
regulation of cell differentiation GO:0045595 320 0.076
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
transmembrane transport GO:0055085 412 0.070
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.070
homeostatic process GO:0042592 331 0.069
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.068
regulation of cell proliferation GO:0042127 359 0.068
positive regulation of biosynthetic process GO:0009891 319 0.067
cellular homeostasis GO:0019725 252 0.067
positive regulation of nervous system development GO:0051962 178 0.067
Mouse
regulation of secretion GO:0051046 224 0.064
positive regulation of multicellular organismal process GO:0051240 387 0.063
Mouse
sensory perception GO:0007600 101 0.062
inorganic cation transmembrane transport GO:0098662 202 0.062
regulation of neuron projection development GO:0010975 161 0.062
positive regulation of programmed cell death GO:0043068 157 0.062
positive regulation of transport GO:0051050 245 0.062
regulation of cellular component organization GO:0051128 368 0.059
regulation of programmed cell death GO:0043067 341 0.059
positive regulation of cellular biosynthetic process GO:0031328 295 0.059
secretion GO:0046903 307 0.058
catabolic process GO:0009056 351 0.058
immune system process GO:0002376 204 0.057
multicellular organismal reproductive process GO:0048609 233 0.057
regulation of cell development GO:0060284 263 0.057
Mouse
negative regulation of rna biosynthetic process GO:1902679 118 0.054
regulation of nervous system development GO:0051960 264 0.051
Mouse
central nervous system development GO:0007417 311 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
response to hypoxia GO:0001666 231 0.049
skeletal system development GO:0001501 41 0.048
Mouse
regulation of molecular function GO:0065009 398 0.048
chemical homeostasis GO:0048878 292 0.048
cellular catabolic process GO:0044248 295 0.047
regulation of anatomical structure size GO:0090066 135 0.047
neuron apoptotic process GO:0051402 88 0.047
cation transmembrane transport GO:0098655 263 0.046
response to oxygen levels GO:0070482 265 0.046
nitrogen compound transport GO:0071705 229 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
negative regulation of cellular component organization GO:0051129 83 0.044
negative regulation of biosynthetic process GO:0009890 168 0.043
regulation of hormone levels GO:0010817 187 0.043
formation of primary germ layer GO:0001704 1 0.043
negative regulation of multicellular organismal process GO:0051241 203 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
parasympathetic nervous system development GO:0048486 1 0.041
regulation of cellular localization GO:0060341 263 0.041
cardiac ventricle development GO:0003231 1 0.041
regulation of protein metabolic process GO:0051246 289 0.040
reproduction GO:0000003 245 0.039
negative regulation of neurogenesis GO:0050768 78 0.038
inorganic ion transmembrane transport GO:0098660 229 0.038
organelle organization GO:0006996 266 0.038
camera type eye development GO:0043010 48 0.037
cation homeostasis GO:0055080 195 0.036
reproductive structure development GO:0048608 128 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
cellular component biogenesis GO:0044085 368 0.036
single organism reproductive process GO:0044702 297 0.035
carbohydrate metabolic process GO:0005975 130 0.035
cellular metal ion homeostasis GO:0006875 172 0.035
locomotion GO:0040011 237 0.034
Worm
cellular potassium ion transport GO:0071804 72 0.034
axon development GO:0061564 96 0.034
gland development GO:0048732 155 0.033
Mouse
response to corticosteroid GO:0031960 235 0.033
regulation of secretion by cell GO:1903530 208 0.033
calcium ion homeostasis GO:0055074 162 0.033
regulation of cell projection organization GO:0031344 175 0.033
dendrite development GO:0016358 72 0.032
multicellular organism reproduction GO:0032504 233 0.032
cell cell signaling GO:0007267 335 0.032
defense response GO:0006952 194 0.031
response to inorganic substance GO:0010035 377 0.031
response to estradiol GO:0032355 164 0.031
reproductive process GO:0022414 372 0.031
positive regulation of cell proliferation GO:0008284 249 0.030
protein complex assembly GO:0006461 263 0.030
negative regulation of cell development GO:0010721 82 0.030
endocytosis GO:0006897 84 0.030
cellular cation homeostasis GO:0030003 180 0.030
cellular response to stress GO:0033554 269 0.029
eye development GO:0001654 50 0.029
regulation of neuron differentiation GO:0045664 208 0.029
Mouse
response to purine containing compound GO:0014074 126 0.029
localization of cell GO:0051674 202 0.028
regulation of cell morphogenesis GO:0022604 77 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.028
ion homeostasis GO:0050801 212 0.028
reproductive system development GO:0061458 128 0.028
cerebral cortex tangential migration GO:0021800 1 0.027
vesicle mediated transport GO:0016192 181 0.027
neuronal action potential GO:0019228 35 0.026
multi organism reproductive process GO:0044703 262 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
Mouse
response to alkaloid GO:0043279 132 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
Mouse
cellular response to acid chemical GO:0071229 75 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
muscle system process GO:0003012 115 0.026
cell differentiation involved in kidney development GO:0061005 4 0.026
gastrulation GO:0007369 2 0.025
forebrain development GO:0030900 98 0.025
response to growth factor GO:0070848 189 0.025
negative regulation of signal transduction GO:0009968 83 0.025
cellular component movement GO:0006928 248 0.025
metal ion transport GO:0030001 289 0.025
metal ion homeostasis GO:0055065 186 0.025
negative regulation of cell death GO:0060548 229 0.025
neuron projection development GO:0031175 273 0.025
response to extracellular stimulus GO:0009991 380 0.025
signal release GO:0023061 145 0.025
glucose homeostasis GO:0042593 75 0.024
response to external biotic stimulus GO:0043207 221 0.024
cellular component assembly GO:0022607 360 0.024
negative regulation of nervous system development GO:0051961 79 0.024
cell projection organization GO:0030030 302 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
gliogenesis GO:0042063 93 0.023
response to fatty acid GO:0070542 65 0.023
growth GO:0040007 165 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
response to nutrient GO:0007584 248 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
response to decreased oxygen levels GO:0036293 237 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
response to peptide hormone GO:0043434 278 0.022
cellular ketone metabolic process GO:0042180 51 0.022
autonomic nervous system development GO:0048483 3 0.022
schwann cell migration GO:0036135 2 0.022
response to glucose GO:0009749 136 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
Mouse Worm
regulation of blood vessel size GO:0050880 89 0.022
cerebellar cortex formation GO:0021697 2 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.021
cerebral cortex cell migration GO:0021795 4 0.021
thyroid gland development GO:0030878 1 0.021
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.021
dendrite morphogenesis GO:0048813 43 0.021
negative regulation of neuron projection development GO:0010977 46 0.021
negative regulation of cell projection organization GO:0031345 50 0.020
regulation of blood circulation GO:1903522 110 0.020
regulation of immune system process GO:0002682 123 0.020
regulation of hydrolase activity GO:0051336 143 0.020
single organism membrane organization GO:0044802 74 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
mesoderm development GO:0007498 2 0.020
cardiac muscle tissue morphogenesis GO:0055008 1 0.020
regulation of tube size GO:0035150 89 0.020
regulation of stem cell differentiation GO:2000736 2 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.020
positive regulation of response to stimulus GO:0048584 285 0.019
potassium ion transmembrane transport GO:0071805 71 0.019
regulation of cell growth GO:0001558 85 0.019
embryonic skeletal system development GO:0048706 3 0.019
Mouse
action potential GO:0001508 54 0.019
lipid biosynthetic process GO:0008610 128 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of catalytic activity GO:0050790 304 0.019
epithelial cell differentiation GO:0030855 71 0.019
negative regulation of molecular function GO:0044092 133 0.019
single organism biosynthetic process GO:0044711 342 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
feeding behavior GO:0007631 53 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
protein complex biogenesis GO:0070271 263 0.018
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 1 0.018
positive regulation of immune system process GO:0002684 90 0.018
epiboly involved in wound healing GO:0090505 2 0.018
immune effector process GO:0002252 53 0.018
response to metal ion GO:0010038 253 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
Mouse
cation transport GO:0006812 382 0.018
cerebellar cortex morphogenesis GO:0021696 2 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
cell differentiation in hindbrain GO:0021533 2 0.017
embryonic cranial skeleton morphogenesis GO:0048701 2 0.017
response to nutrient levels GO:0031667 370 0.017
positive regulation of ion transport GO:0043270 94 0.017
positive regulation of neuron apoptotic process GO:0043525 33 0.017
diencephalon development GO:0021536 21 0.017
aging GO:0007568 241 0.016
neuron differentiation GO:0030182 368 0.016
Mouse
cartilage development GO:0051216 22 0.016
Mouse
positive regulation of developmental process GO:0051094 283 0.016
Mouse
antral ovarian follicle growth GO:0001547 3 0.016
sex differentiation GO:0007548 113 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
odontogenesis GO:0042476 32 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
cell morphogenesis GO:0000902 142 0.016
regulation of extent of cell growth GO:0061387 25 0.016
nucleoside metabolic process GO:0009116 179 0.015
cellular component morphogenesis GO:0032989 155 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
muscle contraction GO:0006936 88 0.015
regulation of phosphorylation GO:0042325 248 0.015
lymphocyte homeostasis GO:0002260 2 0.015
epithelium development GO:0060429 96 0.015
glial cell migration GO:0008347 11 0.015
behavioral response to nicotine GO:0035095 2 0.015
fatty acid metabolic process GO:0006631 99 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
substrate dependent cerebral cortex tangential migration GO:0021825 1 0.015
single organism organelle organization GO:1902589 180 0.015
amide transport GO:0042886 105 0.015
myeloid cell differentiation GO:0030099 22 0.015
membrane organization GO:0061024 94 0.015
myeloid leukocyte activation GO:0002274 36 0.015
cell proliferation in external granule layer GO:0021924 1 0.015
hormone transport GO:0009914 121 0.014
hematopoietic or lymphoid organ development GO:0048534 36 0.014
regulation of catabolic process GO:0009894 113 0.014
axonogenesis GO:0007409 71 0.014
hindbrain morphogenesis GO:0021575 2 0.014
detection of visible light GO:0009584 3 0.014
mesoderm morphogenesis GO:0048332 1 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
endocrine system development GO:0035270 30 0.014
Mouse
peptide transport GO:0015833 97 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
proteolysis GO:0006508 175 0.014
cardiac chamber development GO:0003205 1 0.014
peptide secretion GO:0002790 86 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
axon choice point recognition GO:0016198 2 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
Mouse
maternal process involved in female pregnancy GO:0060135 38 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
organic hydroxy compound transport GO:0015850 77 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
organic substance catabolic process GO:1901575 316 0.014
behavior GO:0007610 205 0.013
glandular epithelial cell differentiation GO:0002067 4 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
glucagon secretion GO:0070091 5 0.013
mesoderm formation GO:0001707 1 0.013
response to peptide GO:1901652 292 0.013
nucleotide metabolic process GO:0009117 279 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
spermatogenesis GO:0007283 99 0.013
negative regulation of transport GO:0051051 136 0.013
regulation of signal transduction GO:0009966 318 0.013
axon midline choice point recognition GO:0016199 2 0.013
response to biotic stimulus GO:0009607 226 0.013
cell migration GO:0016477 197 0.013
histone h3 acetylation GO:0043966 2 0.013
alcohol metabolic process GO:0006066 77 0.013
cell motility GO:0048870 202 0.013
immune response GO:0006955 104 0.012
mammary gland development GO:0030879 38 0.012
positive regulation of signaling GO:0023056 270 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regulation of calcium ion dependent exocytosis GO:0017158 11 0.012
hormone secretion GO:0046879 115 0.012
neuron development GO:0048666 286 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
protein processing GO:0016485 68 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
developmental growth GO:0048589 100 0.012
cognition GO:0050890 92 0.012
lens fiber cell differentiation GO:0070306 3 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
facial nerve development GO:0021561 1 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of locomotion GO:0040012 148 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
neural crest cell differentiation GO:0014033 2 0.012
fertilization GO:0009566 3 0.012
transmission of nerve impulse GO:0019226 42 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
sensory perception of light stimulus GO:0050953 3 0.012
regulation of axon extension GO:0030516 24 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
forebrain neuron development GO:0021884 3 0.012
positive regulation of neuron death GO:1901216 43 0.012
inflammatory response GO:0006954 150 0.012
positive regulation of molecular function GO:0044093 230 0.012
calcium ion import GO:0070509 22 0.012
positive regulation of cell communication GO:0010647 271 0.012
cell growth GO:0016049 104 0.012
cilium morphogenesis GO:0060271 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
neuron projection guidance GO:0097485 24 0.011
cell fate determination GO:0001709 2 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
epithelial cell proliferation GO:0050673 54 0.011
connective tissue development GO:0061448 33 0.011
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.011
purinergic receptor signaling pathway GO:0035587 10 0.011
tube formation GO:0035148 3 0.011
hypothalamus development GO:0021854 11 0.011
regulation of hormone secretion GO:0046883 106 0.011
heart development GO:0007507 72 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
neuron fate commitment GO:0048663 4 0.011
cellular amine metabolic process GO:0044106 38 0.011
protein phosphorylation GO:0006468 345 0.011
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.011
regulation of growth GO:0040008 105 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
regulation of amine transport GO:0051952 54 0.011
positive regulation of cell development GO:0010720 176 0.011
Mouse
olfactory bulb interneuron differentiation GO:0021889 1 0.011
sexual reproduction GO:0019953 148 0.011
palate development GO:0060021 2 0.011
tube morphogenesis GO:0035239 23 0.011
monovalent inorganic cation homeostasis GO:0055067 36 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
visual perception GO:0007601 3 0.011
epithelial cell differentiation involved in kidney development GO:0035850 3 0.011
neural crest cell development GO:0014032 2 0.011
response to electrical stimulus GO:0051602 56 0.011
regulation of blood pressure GO:0008217 83 0.011
positive regulation of blood circulation GO:1903524 65 0.011
regulation of dendrite development GO:0050773 59 0.010
negative regulation of signaling GO:0023057 157 0.010
carboxylic acid transport GO:0046942 115 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
neural crest cell migration GO:0001755 1 0.010
amine metabolic process GO:0009308 38 0.010
macromolecular complex assembly GO:0065003 273 0.010
cellular protein localization GO:0034613 122 0.010
salivary gland development GO:0007431 3 0.010
regulation of epithelial to mesenchymal transition GO:0010717 2 0.010
dna integrity checkpoint GO:0031570 2 0.010
organic anion transport GO:0015711 132 0.010
response to acid chemical GO:0001101 222 0.010
cellular response to lipid GO:0071396 201 0.010
response to carbohydrate GO:0009743 183 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
cellular protein complex assembly GO:0043623 44 0.010
cerebellum morphogenesis GO:0021587 2 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
female gonad development GO:0008585 53 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
bone development GO:0060348 25 0.010
intestinal absorption GO:0050892 3 0.010
erythrocyte differentiation GO:0030218 1 0.010
single organism intracellular transport GO:1902582 166 0.010
neuron projection morphogenesis GO:0048812 122 0.010
lipid storage GO:0019915 1 0.010

Hoxd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
musculoskeletal system disease DOID:17 0 0.030
connective tissue disease DOID:65 0 0.030
cardiovascular system disease DOID:1287 0 0.028
nervous system disease DOID:863 0 0.028
bone disease DOID:0080001 0 0.018
vascular disease DOID:178 0 0.014
artery disease DOID:0050828 0 0.011
urinary system disease DOID:18 0 0.010
retinal disease DOID:5679 0 0.010
night blindness DOID:8499 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010