Rattus norvegicus

48 known processes

Hsd17b2

hydroxysteroid (17-beta) dehydrogenase 2

Hsd17b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.801
Rat
organic acid metabolic process GO:0006082 292 0.559
Rat
response to corticosteroid GO:0031960 235 0.506
Rat
oxoacid metabolic process GO:0043436 290 0.479
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.459
Rat
response to peptide hormone GO:0043434 278 0.450
Rat
organic acid biosynthetic process GO:0016053 83 0.441
Rat
response to extracellular stimulus GO:0009991 380 0.437
Rat
liver development GO:0001889 90 0.424
Rat
response to glucocorticoid GO:0051384 223 0.389
Rat
response to estrogen GO:0043627 232 0.369
Rat
response to nutrient levels GO:0031667 370 0.347
Rat
response to vitamin GO:0033273 131 0.235
carboxylic acid metabolic process GO:0019752 289 0.232
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.224
Rat
response to transition metal nanoparticle GO:1990267 122 0.224
response to peptide GO:1901652 292 0.200
Rat
response to acid chemical GO:0001101 222 0.188
Human
gland development GO:0048732 155 0.170
Rat
cellular lipid metabolic process GO:0044255 208 0.166
Rat
response to camp GO:0051591 91 0.156
cellular response to hormone stimulus GO:0032870 247 0.156
response to inorganic substance GO:0010035 377 0.147
single organism reproductive process GO:0044702 297 0.144
Mouse
response to metal ion GO:0010038 253 0.136
cellular amino acid metabolic process GO:0006520 107 0.134
cellular response to endogenous stimulus GO:0071495 377 0.129
regulation of hormone levels GO:0010817 187 0.124
response to toxic substance GO:0009636 133 0.121
Rat
intestinal absorption GO:0050892 3 0.113
cellular response to lipid GO:0071396 201 0.100
cellular response to peptide hormone stimulus GO:0071375 120 0.095
multi organism reproductive process GO:0044703 262 0.088
Rat
lipid metabolic process GO:0006629 283 0.081
monocarboxylic acid biosynthetic process GO:0072330 48 0.080
Rat
cellular response to external stimulus GO:0071496 118 0.079
cellular ketone metabolic process GO:0042180 51 0.076
cellular response to organic cyclic compound GO:0071407 202 0.073
regeneration GO:0031099 163 0.072
cellular response to steroid hormone stimulus GO:0071383 93 0.072
response to carbohydrate GO:0009743 183 0.071
cellular response to nitrogen compound GO:1901699 210 0.071
cellular response to corticosteroid stimulus GO:0071384 69 0.070
cellular response to oxygen containing compound GO:1901701 386 0.070
hepaticobiliary system development GO:0061008 90 0.069
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.066
response to acetate GO:0010034 3 0.066
cellular hormone metabolic process GO:0034754 49 0.065
response to organophosphorus GO:0046683 102 0.065
response to estradiol GO:0032355 164 0.063
Rat
macromolecular complex subunit organization GO:0043933 339 0.062
response to food GO:0032094 27 0.061
Rat
response to xenobiotic stimulus GO:0009410 23 0.060
response to decreased oxygen levels GO:0036293 237 0.059
Rat
response to insulin GO:0032868 133 0.059
Rat
multi multicellular organism process GO:0044706 138 0.058
Rat
organ regeneration GO:0031100 101 0.058
multicellular organism reproduction GO:0032504 233 0.058
response to oxygen levels GO:0070482 265 0.056
Rat
cellular response to organonitrogen compound GO:0071417 197 0.054
cellular component assembly GO:0022607 360 0.054
cellular component biogenesis GO:0044085 368 0.052
cellular response to glucocorticoid stimulus GO:0071385 68 0.050
catabolic process GO:0009056 351 0.050
organic anion transport GO:0015711 132 0.050
response to hypoxia GO:0001666 231 0.049
Rat
cellular response to insulin stimulus GO:0032869 81 0.049
amine metabolic process GO:0009308 38 0.048
lipid biosynthetic process GO:0008610 128 0.048
response to purine containing compound GO:0014074 126 0.048
single organism catabolic process GO:0044712 283 0.047
response to vitamin b6 GO:0034516 1 0.045
response to retinoic acid GO:0032526 63 0.044
Human
response to vitamin a GO:0033189 36 0.044
negative regulation of serine type endopeptidase activity GO:1900004 1 0.043
reproductive process GO:0022414 372 0.043
Mouse Rat
cofactor metabolic process GO:0051186 95 0.043
pyruvate metabolic process GO:0006090 27 0.043
response to amino acid GO:0043200 75 0.042
protein complex biogenesis GO:0070271 263 0.042
anion transport GO:0006820 178 0.040
fatty acid oxidation GO:0019395 29 0.040
chemical homeostasis GO:0048878 292 0.039
oxidation reduction process GO:0055114 304 0.038
response to herbicide GO:0009635 16 0.038
coenzyme metabolic process GO:0006732 86 0.038
cellular amine metabolic process GO:0044106 38 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
protein complex subunit organization GO:0071822 302 0.037
isoprenoid metabolic process GO:0006720 45 0.036
Rat
cellular response to peptide GO:1901653 133 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
single organism biosynthetic process GO:0044711 342 0.036
response to oxidative stress GO:0006979 186 0.035
aging GO:0007568 241 0.035
cellular response to stress GO:0033554 269 0.035
response to mechanical stimulus GO:0009612 134 0.035
c21 steroid hormone metabolic process GO:0008207 14 0.034
response to fungicide GO:0060992 20 0.034
programmed cell death GO:0012501 392 0.034
c21 steroid hormone biosynthetic process GO:0006700 10 0.033
diterpenoid metabolic process GO:0016101 33 0.033
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.033
steroid metabolic process GO:0008202 73 0.032
monocarboxylic acid transport GO:0015718 52 0.032
phthalate metabolic process GO:0018963 8 0.031
circadian rhythm GO:0007623 88 0.031
lipid localization GO:0010876 62 0.031
cellular catabolic process GO:0044248 295 0.031
cellular response to camp GO:0071320 26 0.030
response to interleukin 1 GO:0070555 55 0.030
fatty acid metabolic process GO:0006631 99 0.030
regulation of growth GO:0040008 105 0.030
estrogen biosynthetic process GO:0006703 6 0.029
response to other organism GO:0051707 220 0.029
vasodilation GO:0042311 44 0.028
response to triglyceride GO:0034014 3 0.028
regulation of programmed cell death GO:0043067 341 0.028
response to ketone GO:1901654 182 0.028
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.028
acylglycerol metabolic process GO:0006639 21 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
response to zinc ion GO:0010043 39 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
response to ionizing radiation GO:0010212 59 0.027
hepatocyte differentiation GO:0070365 8 0.025
protein complex assembly GO:0006461 263 0.025
homeostatic process GO:0042592 331 0.025
negative regulation of gene expression GO:0010629 199 0.025
reproductive system development GO:0061458 128 0.025
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.025
lipid transport GO:0006869 61 0.025
response to testosterone GO:0033574 55 0.025
response to lead ion GO:0010288 33 0.024
carbohydrate metabolic process GO:0005975 130 0.024
regulation of anatomical structure size GO:0090066 135 0.024
response to external biotic stimulus GO:0043207 221 0.024
cellular response to interferon gamma GO:0071346 14 0.024
response to monosaccharide GO:0034284 159 0.024
androgen biosynthetic process GO:0006702 10 0.024
developmental growth GO:0048589 100 0.024
progesterone metabolic process GO:0042448 8 0.024
spermatogenesis GO:0007283 99 0.024
anion transmembrane transport GO:0098656 77 0.024
organophosphate metabolic process GO:0019637 370 0.024
response to cadmium ion GO:0046686 35 0.024
Rat
organic substance catabolic process GO:1901575 316 0.024
cardiac chamber development GO:0003205 1 0.024
negative regulation of molecular function GO:0044092 133 0.023
cellular response to metal ion GO:0071248 55 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
cellular response to vitamin e GO:0071306 3 0.023
transmission of nerve impulse GO:0019226 42 0.023
hormone metabolic process GO:0042445 69 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
response to bacterium GO:0009617 200 0.022
neutral lipid metabolic process GO:0006638 21 0.022
growth GO:0040007 165 0.022
terpenoid metabolic process GO:0006721 37 0.022
Rat
response to insecticide GO:0017085 21 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
reproduction GO:0000003 245 0.021
circulatory system process GO:0003013 183 0.021
Rat
protein maturation GO:0051604 68 0.021
cellular response to ketone GO:1901655 51 0.021
regulation of molecular function GO:0065009 398 0.020
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.020
extracellular matrix constituent secretion GO:0070278 4 0.020
neuron differentiation GO:0030182 368 0.020
proteolysis GO:0006508 175 0.020
regulation of extracellular matrix constituent secretion GO:0003330 2 0.020
cellular response to gonadotropin stimulus GO:0071371 17 0.020
cellular homeostasis GO:0019725 252 0.020
aromatic compound catabolic process GO:0019439 168 0.020
response to corticosterone GO:0051412 40 0.019
Rat
cellular response to interleukin 1 GO:0071347 37 0.019
carboxylic acid transport GO:0046942 115 0.019
response to cytokine GO:0034097 215 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
heart morphogenesis GO:0003007 3 0.019
regulation of catalytic activity GO:0050790 304 0.019
protein processing GO:0016485 68 0.019
head development GO:0060322 247 0.019
Rat
response to reactive oxygen species GO:0000302 120 0.018
sulfur compound metabolic process GO:0006790 70 0.018
reproductive structure development GO:0048608 128 0.018
Mouse
sexual reproduction GO:0019953 148 0.018
negative regulation of metabolic process GO:0009892 331 0.018
neurological system process GO:0050877 219 0.018
tissue development GO:0009888 252 0.018
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
catenin import into nucleus GO:0035411 1 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.017
nitrogen compound transport GO:0071705 229 0.017
cellular response to xenobiotic stimulus GO:0071466 19 0.017
regulation of cellular component organization GO:0051128 368 0.017
developmental process involved in reproduction GO:0003006 159 0.017
Mouse
amide transport GO:0042886 105 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of blood pressure GO:0008217 83 0.017
Rat
behavior GO:0007610 205 0.016
response to lipopolysaccharide GO:0032496 191 0.016
rhythmic process GO:0048511 156 0.016
hexose metabolic process GO:0019318 58 0.016
pancreatic stellate cell proliferation GO:0072343 2 0.016
macromolecular complex assembly GO:0065003 273 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
vitamin d receptor signaling pathway GO:0070561 1 0.016
response to mercury ion GO:0046689 15 0.016
sterol homeostasis GO:0055092 3 0.016
transcription dna templated GO:0006351 377 0.016
lipid catabolic process GO:0016042 46 0.016
ion homeostasis GO:0050801 212 0.016
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
response to hyperoxia GO:0055093 45 0.016
negative regulation of apoptotic process GO:0043066 181 0.015
insecticide metabolic process GO:0017143 4 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
lipid oxidation GO:0034440 30 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of serine type endopeptidase activity GO:1900003 1 0.015
placenta development GO:0001890 22 0.015
Mouse
regulation of ion transport GO:0043269 245 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
cellular response to oxidative stress GO:0034599 76 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
regulation of apoptotic process GO:0042981 335 0.014
central nervous system development GO:0007417 311 0.014
Rat
bmp signaling pathway GO:0030509 4 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
cholesterol homeostasis GO:0042632 3 0.014
cellular response to inorganic substance GO:0071241 65 0.014
regulation of protein maturation GO:1903317 50 0.014
multicellular organismal signaling GO:0035637 44 0.014
neuron projection development GO:0031175 273 0.014
regulation of phagocytosis engulfment GO:0060099 4 0.014
glial cell differentiation GO:0010001 65 0.014
rhythmic behavior GO:0007622 24 0.014
response to glucose GO:0009749 136 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to hexose GO:0009746 144 0.014
gamete generation GO:0007276 124 0.014
response to chromate GO:0046687 3 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of phagocytosis engulfment GO:0060100 4 0.013
brain renin angiotensin system GO:0002035 3 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of signaling GO:0023056 270 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of peptide secretion GO:0002791 82 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of tube size GO:0035150 89 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
response to vitamin d GO:0033280 34 0.013
negative regulation of serine type peptidase activity GO:1902572 1 0.013
protein oligomerization GO:0051259 191 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to activity GO:0014823 73 0.013
nucleotide metabolic process GO:0009117 279 0.013
response to vitamin e GO:0033197 24 0.013
negative regulation of peptidase activity GO:0010466 38 0.013
locomotion GO:0040011 237 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
positive regulation of developmental process GO:0051094 283 0.013
cell projection organization GO:0030030 302 0.013
regulation of blood circulation GO:1903522 110 0.012
chromosome segregation GO:0007059 2 0.012
single organism carbohydrate catabolic process GO:0044724 40 0.012
regulation of nervous system development GO:0051960 264 0.012
digestive system development GO:0055123 41 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
xenobiotic metabolic process GO:0006805 19 0.012
regulation of neuronal synaptic plasticity GO:0048168 31 0.012
pyridine containing compound metabolic process GO:0072524 32 0.012
vitamin a metabolic process GO:0006776 2 0.012
regulation of protein processing GO:0070613 50 0.012
response to methanol GO:0033986 1 0.012
positive regulation of transport GO:0051050 245 0.012
antibiotic transport GO:0042891 2 0.012
chemosensory behavior GO:0007635 2 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
phenylpropanoid catabolic process GO:0046271 3 0.012
heterocycle catabolic process GO:0046700 167 0.012
response to temperature stimulus GO:0009266 94 0.012
secretion GO:0046903 307 0.012
inorganic anion transport GO:0015698 41 0.012
carbohydrate catabolic process GO:0016052 40 0.012
telencephalon development GO:0021537 62 0.012
positive regulation of protein metabolic process GO:0051247 178 0.011
isoprenoid biosynthetic process GO:0008299 12 0.011
Rat
lipid storage GO:0019915 1 0.011
response to interferon gamma GO:0034341 20 0.011
sulfur compound biosynthetic process GO:0044272 19 0.011
circadian behavior GO:0048512 24 0.011
apoptotic process GO:0006915 381 0.011
small molecule biosynthetic process GO:0044283 124 0.011
Rat
regulation of serine type peptidase activity GO:1902571 1 0.011
response to calcium ion GO:0051592 59 0.011
phosphatidylethanolamine metabolic process GO:0046337 1 0.011
biphenyl metabolic process GO:0018879 10 0.011
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
axis specification GO:0009798 4 0.011
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.011
monosaccharide metabolic process GO:0005996 61 0.011
positive regulation of molecular function GO:0044093 230 0.011
rna metabolic process GO:0016070 406 0.011
neural crest cell differentiation GO:0014033 2 0.011
cellular response to mechanical stimulus GO:0071260 48 0.011
cellular ion homeostasis GO:0006873 184 0.011
rna biosynthetic process GO:0032774 380 0.011
dibenzo p dioxin metabolic process GO:0018894 10 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.011
positive regulation of extracellular matrix organization GO:1903055 4 0.011
regulation of transcription dna templated GO:0006355 374 0.011
positive regulation of growth GO:0045927 55 0.011
neuron development GO:0048666 286 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
inflammatory response GO:0006954 150 0.011
circadian sleep wake cycle GO:0042745 23 0.011
cellular response to fluid shear stress GO:0071498 4 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
nicotinamide nucleotide metabolic process GO:0046496 28 0.010
protein localization to organelle GO:0033365 57 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
odontogenesis GO:0042476 32 0.010
defense response GO:0006952 194 0.010
regulation of hydrolase activity GO:0051336 143 0.010
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of fatty acid oxidation GO:0046321 6 0.010
positive regulation of fibroblast proliferation GO:0048146 15 0.010
toxin transport GO:1901998 3 0.010
androgen metabolic process GO:0008209 14 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
brain development GO:0007420 247 0.010
Rat
wound healing GO:0042060 122 0.010

Hsd17b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.052
congenital adrenal hyperplasia DOID:0050811 0 0.031
lipid metabolism disorder DOID:3146 0 0.031
inherited metabolic disorder DOID:655 0 0.031
steroid inherited metabolic disorder DOID:1701 0 0.031
acquired metabolic disease DOID:0060158 0 0.014
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011