Rattus norvegicus

0 known processes

Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

Hsd17b7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 128 0.410
lipid metabolic process GO:0006629 283 0.345
cholesterol metabolic process GO:0008203 17 0.278
cellular lipid metabolic process GO:0044255 208 0.219
steroid metabolic process GO:0008202 73 0.182
single organism biosynthetic process GO:0044711 342 0.162
cellular response to nitrogen compound GO:1901699 210 0.146
steroid biosynthetic process GO:0006694 48 0.088
cellular response to oxygen containing compound GO:1901701 386 0.082
response to biotic stimulus GO:0009607 226 0.079
secretion GO:0046903 307 0.077
transmembrane transport GO:0055085 412 0.070
response to inorganic substance GO:0010035 377 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
regulation of phosphate metabolic process GO:0019220 349 0.053
response to extracellular stimulus GO:0009991 380 0.053
organic hydroxy compound metabolic process GO:1901615 115 0.053
cellular response to stress GO:0033554 269 0.051
cellular response to lipid GO:0071396 201 0.050
response to nutrient GO:0007584 248 0.050
alcohol biosynthetic process GO:0046165 38 0.049
macromolecular complex assembly GO:0065003 273 0.049
regulation of rna biosynthetic process GO:2001141 381 0.048
positive regulation of cell communication GO:0010647 271 0.047
response to nutrient levels GO:0031667 370 0.046
alcohol metabolic process GO:0006066 77 0.046
small molecule biosynthetic process GO:0044283 124 0.041
organic anion transport GO:0015711 132 0.041
tube development GO:0035295 89 0.040
regulation of cellular component organization GO:0051128 368 0.040
regulation of transcription dna templated GO:0006355 374 0.039
chemical homeostasis GO:0048878 292 0.039
brain development GO:0007420 247 0.038
rna metabolic process GO:0016070 406 0.037
programmed cell death GO:0012501 392 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
cofactor metabolic process GO:0051186 95 0.036
positive regulation of cell proliferation GO:0008284 249 0.036
growth GO:0040007 165 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.036
response to other organism GO:0051707 220 0.036
intracellular signal transduction GO:0035556 314 0.035
head development GO:0060322 247 0.035
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.035
transcription dna templated GO:0006351 377 0.034
regulation of rna metabolic process GO:0051252 391 0.034
response to metal ion GO:0010038 253 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.034
anion transport GO:0006820 178 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
response to external biotic stimulus GO:0043207 221 0.033
response to lipopolysaccharide GO:0032496 191 0.033
reproductive process GO:0022414 372 0.032
ion transmembrane transport GO:0034220 365 0.032
organic acid metabolic process GO:0006082 292 0.032
homeostatic process GO:0042592 331 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
cell cell signaling GO:0007267 335 0.032
tissue development GO:0009888 252 0.032
response to ethanol GO:0045471 162 0.031
metal ion transport GO:0030001 289 0.031
cation transport GO:0006812 382 0.031
regulation of secretion GO:0051046 224 0.030
cellular amine metabolic process GO:0044106 38 0.030
regulation of hormone levels GO:0010817 187 0.030
cellular response to organic cyclic compound GO:0071407 202 0.030
cellular response to organonitrogen compound GO:0071417 197 0.030
response to fatty acid GO:0070542 65 0.030
rna biosynthetic process GO:0032774 380 0.030
neuron development GO:0048666 286 0.030
oxoacid metabolic process GO:0043436 290 0.030
cation transmembrane transport GO:0098655 263 0.029
negative regulation of metabolic process GO:0009892 331 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
cellular response to peptide GO:1901653 133 0.029
central nervous system development GO:0007417 311 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.028
cell projection organization GO:0030030 302 0.028
response to organophosphorus GO:0046683 102 0.028
cellular component assembly GO:0022607 360 0.028
positive regulation of signaling GO:0023056 270 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
protein complex assembly GO:0006461 263 0.027
nitrogen compound transport GO:0071705 229 0.027
response to ketone GO:1901654 182 0.027
aging GO:0007568 241 0.027
nucleic acid templated transcription GO:0097659 379 0.027
protein complex biogenesis GO:0070271 263 0.027
regulation of molecular function GO:0065009 398 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
neuron differentiation GO:0030182 368 0.026
response to corticosteroid GO:0031960 235 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
cellular component biogenesis GO:0044085 368 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
regulation of programmed cell death GO:0043067 341 0.026
regulation of cell proliferation GO:0042127 359 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
reproduction GO:0000003 245 0.025
isoprenoid metabolic process GO:0006720 45 0.025
signal release GO:0023061 145 0.024
single organism catabolic process GO:0044712 283 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
multi organism reproductive process GO:0044703 262 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
catabolic process GO:0009056 351 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
protein complex subunit organization GO:0071822 302 0.023
cellular chemical homeostasis GO:0055082 247 0.022
response to oxygen levels GO:0070482 265 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
cellular response to insulin stimulus GO:0032869 81 0.022
macromolecule localization GO:0033036 252 0.022
amide transport GO:0042886 105 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
vesicle mediated transport GO:0016192 181 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
organic substance catabolic process GO:1901575 316 0.021
hormone transport GO:0009914 121 0.021
neuron projection morphogenesis GO:0048812 122 0.021
cellular catabolic process GO:0044248 295 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of transport GO:0051050 245 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
response to peptide GO:1901652 292 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cholesterol biosynthetic process GO:0006695 10 0.020
rhythmic process GO:0048511 156 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
neuron projection development GO:0031175 273 0.020
cellular component morphogenesis GO:0032989 155 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
negative regulation of gene expression GO:0010629 199 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
positive regulation of transcription dna templated GO:0045893 197 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
lipid transport GO:0006869 61 0.019
protein oligomerization GO:0051259 191 0.019
fatty acid metabolic process GO:0006631 99 0.019
cellular response to alcohol GO:0097306 87 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
response to peptide hormone GO:0043434 278 0.019
single organism reproductive process GO:0044702 297 0.019
response to starvation GO:0042594 59 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
heart morphogenesis GO:0003007 3 0.018
regulation of phosphorylation GO:0042325 248 0.018
organelle organization GO:0006996 266 0.018
protein phosphorylation GO:0006468 345 0.018
positive regulation of signal transduction GO:0009967 175 0.018
gonad development GO:0008406 104 0.018
reproductive structure development GO:0048608 128 0.018
sex differentiation GO:0007548 113 0.018
neurological system process GO:0050877 219 0.018
response to radiation GO:0009314 137 0.018
synaptic transmission GO:0007268 235 0.018
regulation of signal transduction GO:0009966 318 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of apoptotic process GO:0042981 335 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
peptide transport GO:0015833 97 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
response to purine containing compound GO:0014074 126 0.017
regulation of nervous system development GO:0051960 264 0.017
sterol metabolic process GO:0016125 18 0.017
axis specification GO:0009798 4 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
cellular component movement GO:0006928 248 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of secretion by cell GO:1903530 208 0.017
cell motility GO:0048870 202 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
cellular response to molecule of bacterial origin GO:0071219 56 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
ras protein signal transduction GO:0007265 29 0.016
regulation of cell growth GO:0001558 85 0.016
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.016
regulation of ion transport GO:0043269 245 0.016
regulation of catalytic activity GO:0050790 304 0.016
cellular cation homeostasis GO:0030003 180 0.016
response to glucose GO:0009749 136 0.016
organic acid transport GO:0015849 116 0.016
regulation of cell differentiation GO:0045595 320 0.016
response to acid chemical GO:0001101 222 0.016
positive regulation of molecular function GO:0044093 230 0.016
response to growth factor GO:0070848 189 0.016
negative regulation of cell death GO:0060548 229 0.016
cell morphogenesis GO:0000902 142 0.016
localization of cell GO:0051674 202 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
response to wounding GO:0009611 254 0.016
hepaticobiliary system development GO:0061008 90 0.016
cell part morphogenesis GO:0032990 123 0.016
regulation of peptide transport GO:0090087 87 0.016
metanephric tubule development GO:0072170 4 0.015
response to low light intensity stimulus GO:0009645 2 0.015
negative regulation of molecular function GO:0044092 133 0.015
response to estradiol GO:0032355 164 0.015
regulation of growth GO:0040008 105 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
carboxylic acid transport GO:0046942 115 0.015
cell growth GO:0016049 104 0.015
regulation of neurogenesis GO:0050767 247 0.015
anterior posterior pattern specification GO:0009952 1 0.015
response to monosaccharide GO:0034284 159 0.015
organic hydroxy compound transport GO:0015850 77 0.015
hormone secretion GO:0046879 115 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of cell development GO:0060284 263 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
cellular metal ion homeostasis GO:0006875 172 0.014
mesoderm development GO:0007498 2 0.014
sterol homeostasis GO:0055092 3 0.014
multicellular organism reproduction GO:0032504 233 0.014
lipid localization GO:0010876 62 0.014
regulation of cellular localization GO:0060341 263 0.014
single organism intracellular transport GO:1902582 166 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
purine containing compound metabolic process GO:0072521 253 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
regulation of neuron differentiation GO:0045664 208 0.014
embryonic pattern specification GO:0009880 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
apoptotic process GO:0006915 381 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
metal ion homeostasis GO:0055065 186 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
response to hexose GO:0009746 144 0.014
response to insulin GO:0032868 133 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
cardiovascular system development GO:0072358 134 0.014
response to interleukin 1 GO:0070555 55 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
secretion by cell GO:0032940 248 0.013
peptide secretion GO:0002790 86 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
proteolysis GO:0006508 175 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
positive regulation of cell growth GO:0030307 44 0.013
ion homeostasis GO:0050801 212 0.013
cellular ion homeostasis GO:0006873 184 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
cholesterol homeostasis GO:0042632 3 0.013
regulation of protein localization GO:0032880 81 0.013
cell migration GO:0016477 197 0.013
forebrain development GO:0030900 98 0.013
multi multicellular organism process GO:0044706 138 0.013
peptide hormone secretion GO:0030072 84 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
cation homeostasis GO:0055080 195 0.013
behavior GO:0007610 205 0.013
locomotion GO:0040011 237 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of anatomical structure size GO:0090066 135 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to estrogen GO:0043627 232 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to hypoxia GO:0001666 231 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
response to bacterium GO:0009617 200 0.012
response to temperature stimulus GO:0009266 94 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
renal system development GO:0072001 67 0.012
regeneration GO:0031099 163 0.012
intracellular transport GO:0046907 185 0.012
regulation of protein metabolic process GO:0051246 289 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
regulation of system process GO:0044057 208 0.012
organophosphate metabolic process GO:0019637 370 0.012
single organism behavior GO:0044708 130 0.012
endoplasmic reticulum organization GO:0007029 1 0.012
response to cytokine GO:0034097 215 0.012
regulation of hormone secretion GO:0046883 106 0.012
circulatory system development GO:0072359 134 0.012
gamete generation GO:0007276 124 0.012
positive regulation of developmental process GO:0051094 283 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
cell type specific apoptotic process GO:0097285 134 0.012
immune system process GO:0002376 204 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
regulation of neuron projection development GO:0010975 161 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of developmental growth GO:0048638 45 0.011
membrane organization GO:0061024 94 0.011
positive regulation of gene expression GO:0010628 244 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
adult locomotory behavior GO:0008344 4 0.011
circadian regulation of gene expression GO:0032922 3 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
rna localization GO:0006403 4 0.011
carbohydrate homeostasis GO:0033500 75 0.011
urea cycle GO:0000050 5 0.011
regulation of peptide secretion GO:0002791 82 0.011
striated muscle tissue development GO:0014706 58 0.011
salivary gland development GO:0007431 3 0.011
digestive system development GO:0055123 41 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
cell cycle checkpoint GO:0000075 2 0.011
eye morphogenesis GO:0048592 4 0.011
response to vitamin GO:0033273 131 0.011
regulation of response to stress GO:0080134 126 0.011
peptidyl amino acid modification GO:0018193 126 0.011
defense response GO:0006952 194 0.011
positive regulation of apoptotic process GO:0043065 154 0.010
positive regulation of isotype switching GO:0045830 1 0.010
positive regulation of nervous system development GO:0051962 178 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
nucleoside metabolic process GO:0009116 179 0.010
muscle cell apoptotic process GO:0010657 30 0.010
nucleotide metabolic process GO:0009117 279 0.010
female pregnancy GO:0007565 122 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
response to oxidative stress GO:0006979 186 0.010
wound healing GO:0042060 122 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
single organism organelle organization GO:1902589 180 0.010
regulation of cell projection organization GO:0031344 175 0.010
negative regulation of developmental process GO:0051093 125 0.010
divalent inorganic cation transport GO:0072511 134 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
s shaped body morphogenesis GO:0072050 2 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
gland development GO:0048732 155 0.010

Hsd17b7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.011