Rattus norvegicus

164 known processes

Hspa1a

heat shock 70kD protein 1A

(Aliases: Hspa1b,Hspa1,HSP72,Hsp70-1)

Hspa1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to heat GO:0009408 60 0.863
Yeast
protein refolding GO:0042026 3 0.821
cold acclimation GO:0009631 1 0.684
regulation of programmed cell death GO:0043067 341 0.557
negative regulation of cellular metabolic process GO:0031324 281 0.401
regulation of cell development GO:0060284 263 0.372
programmed cell death GO:0012501 392 0.361
cellular component biogenesis GO:0044085 368 0.334
chlorinated hydrocarbon metabolic process GO:0042196 4 0.307
multicellular organism reproduction GO:0032504 233 0.305
regulation of catalytic activity GO:0050790 304 0.281
positive regulation of cell death GO:0010942 184 0.278
negative regulation of programmed cell death GO:0043069 183 0.278
tissue development GO:0009888 252 0.268
response to temperature stimulus GO:0009266 94 0.267
Yeast
negative regulation of cell death GO:0060548 229 0.261
signal transduction by phosphorylation GO:0023014 144 0.259
protein targeting GO:0006605 61 0.247
Yeast
response to hydrogen peroxide GO:0042542 89 0.247
mapk cascade GO:0000165 140 0.230
regulation of rna biosynthetic process GO:2001141 381 0.220
purine containing compound metabolic process GO:0072521 253 0.219
Rat
regulation of phosphate metabolic process GO:0019220 349 0.214
cellular response to stress GO:0033554 269 0.211
Yeast Fly
negative regulation of molecular function GO:0044092 133 0.196
positive regulation of multicellular organismal process GO:0051240 387 0.193
response to inorganic substance GO:0010035 377 0.190
response to other organism GO:0051707 220 0.184
regulation of phosphorus metabolic process GO:0051174 349 0.182
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.174
reproductive process GO:0022414 372 0.173
positive regulation of rna metabolic process GO:0051254 203 0.171
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.166
stress activated protein kinase signaling cascade GO:0031098 37 0.166
angiogenesis GO:0001525 53 0.166
negative regulation of apoptotic process GO:0043066 181 0.160
apoptotic process GO:0006915 381 0.157
neuron differentiation GO:0030182 368 0.150
regulation of angiogenesis GO:0045765 39 0.149
ribonucleoside triphosphate catabolic process GO:0009203 122 0.147
Rat
aromatic compound catabolic process GO:0019439 168 0.147
Rat
negative regulation of protein metabolic process GO:0051248 114 0.146
localization of cell GO:0051674 202 0.141
reactive oxygen species metabolic process GO:0072593 37 0.138
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.134
cellular response to oxygen containing compound GO:1901701 386 0.134
response to cold GO:0009409 29 0.133
protein phosphorylation GO:0006468 345 0.128
negative regulation of metabolic process GO:0009892 331 0.128
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.127
cellular response to cytokine stimulus GO:0071345 127 0.127
organelle organization GO:0006996 266 0.126
regulation of cell proliferation GO:0042127 359 0.125
regulation of phosphorylation GO:0042325 248 0.124
cellular response to hormone stimulus GO:0032870 247 0.123
nucleoside catabolic process GO:0009164 126 0.123
Rat
regulation of rna metabolic process GO:0051252 391 0.122
cellular catabolic process GO:0044248 295 0.121
Rat
blood vessel development GO:0001568 69 0.119
response to oxidative stress GO:0006979 186 0.119
response to estradiol GO:0032355 164 0.119
response to hypoxia GO:0001666 231 0.114
nucleoside metabolic process GO:0009116 179 0.114
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.114
Rat
negative regulation of gene expression GO:0010629 199 0.111
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.107
single organism reproductive process GO:0044702 297 0.107
intracellular signal transduction GO:0035556 314 0.106
positive regulation of molecular function GO:0044093 230 0.106
regulation of system process GO:0044057 208 0.106
response to reactive oxygen species GO:0000302 120 0.106
vasculature development GO:0001944 70 0.105
cell growth GO:0016049 104 0.104
negative regulation of cellular protein metabolic process GO:0032269 106 0.103
regulation of signal transduction GO:0009966 318 0.100
regulation of reactive oxygen species metabolic process GO:2000377 26 0.099
cellular component assembly GO:0022607 360 0.098
response to extracellular stimulus GO:0009991 380 0.097
nucleoside triphosphate catabolic process GO:0009143 123 0.097
Rat
gamete generation GO:0007276 124 0.096
regulation of nucleic acid templated transcription GO:1903506 380 0.096
regulation of apoptotic process GO:0042981 335 0.095
positive regulation of developmental process GO:0051094 283 0.094
chaperone mediated protein folding GO:0061077 6 0.094
Rat
circulatory system development GO:0072359 134 0.094
purine nucleotide catabolic process GO:0006195 136 0.093
Rat
neuron development GO:0048666 286 0.092
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.091
regulation of protein kinase activity GO:0045859 105 0.090
purine ribonucleoside metabolic process GO:0046128 168 0.088
Rat
response to molecule of bacterial origin GO:0002237 194 0.088
nucleoside phosphate metabolic process GO:0006753 283 0.088
Rat
regulation of protein phosphorylation GO:0001932 183 0.087
response to bacterium GO:0009617 200 0.085
glycosyl compound metabolic process GO:1901657 182 0.085
Rat
stress activated mapk cascade GO:0051403 35 0.085
female pregnancy GO:0007565 122 0.083
regulation of cellular component organization GO:0051128 368 0.083
aging GO:0007568 241 0.082
positive regulation of rna biosynthetic process GO:1902680 197 0.081
positive regulation of cell proliferation GO:0008284 249 0.081
carbohydrate derivative catabolic process GO:1901136 147 0.080
Rat
cell type specific apoptotic process GO:0097285 134 0.079
positive regulation of programmed cell death GO:0043068 157 0.079
halogenated hydrocarbon metabolic process GO:0042197 4 0.077
regulation of intracellular signal transduction GO:1902531 218 0.074
cellular response to fluid shear stress GO:0071498 4 0.074
muscle system process GO:0003012 115 0.074
response to biotic stimulus GO:0009607 226 0.074
regulation of molecular function GO:0065009 398 0.073
anatomical structure morphogenesis GO:0009653 298 0.072
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.072
cellular response to oxidative stress GO:0034599 76 0.071
positive regulation of gene expression GO:0010628 244 0.070
response to peptide GO:1901652 292 0.069
rna biosynthetic process GO:0032774 380 0.069
negative regulation of neuron apoptotic process GO:0043524 45 0.069
detection of stimulus GO:0051606 24 0.069
response to estrogen GO:0043627 232 0.067
regulation of cytokine production GO:0001817 56 0.067
response to oxygen levels GO:0070482 265 0.066
regulation of muscle system process GO:0090257 79 0.066
locomotion GO:0040011 237 0.066
Fly
single organism organelle organization GO:1902589 180 0.065
regulation of catabolic process GO:0009894 113 0.065
cell projection organization GO:0030030 302 0.065
Fly
nucleoside monophosphate catabolic process GO:0009125 56 0.065
Rat
cell motility GO:0048870 202 0.064
purine nucleoside triphosphate metabolic process GO:0009144 141 0.063
Rat
positive regulation of neurogenesis GO:0050769 165 0.063
cellular protein localization GO:0034613 122 0.063
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.063
Rat
purine nucleoside metabolic process GO:0042278 169 0.061
Rat
response to purine containing compound GO:0014074 126 0.061
cellular response to endogenous stimulus GO:0071495 377 0.061
regulation of neurogenesis GO:0050767 247 0.061
response to decreased oxygen levels GO:0036293 237 0.060
organic acid metabolic process GO:0006082 292 0.060
negative regulation of nucleic acid templated transcription GO:1903507 117 0.060
regulation of muscle contraction GO:0006937 53 0.060
response to laminar fluid shear stress GO:0034616 9 0.059
nucleic acid templated transcription GO:0097659 379 0.058
regulation of cellular protein metabolic process GO:0032268 267 0.058
transcription dna templated GO:0006351 377 0.057
growth GO:0040007 165 0.057
regulation of cellular component movement GO:0051270 150 0.056
regulation of vasculature development GO:1901342 44 0.056
cellular nitrogen compound catabolic process GO:0044270 163 0.055
Rat
regulation of cellular catabolic process GO:0031329 101 0.055
microtubule polymerization or depolymerization GO:0031109 13 0.054
regulation of protein metabolic process GO:0051246 289 0.054
negative regulation of phosphate metabolic process GO:0045936 80 0.054
cellular response to organic cyclic compound GO:0071407 202 0.053
organophosphate metabolic process GO:0019637 370 0.053
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.053
Rat
positive regulation of angiogenesis GO:0045766 28 0.053
multicellular organismal reproductive process GO:0048609 233 0.053
regulation of purine nucleotide metabolic process GO:1900542 115 0.053
purine containing compound catabolic process GO:0072523 138 0.051
Rat
response to cytokine GO:0034097 215 0.051
regulation of nervous system development GO:0051960 264 0.051
protein folding GO:0006457 12 0.051
Yeast Rat
response to corticosteroid GO:0031960 235 0.050
positive regulation of transcription dna templated GO:0045893 197 0.050
intracellular transport GO:0046907 185 0.050
Yeast
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.050
Fly
multi organism reproductive process GO:0044703 262 0.049
positive regulation of catalytic activity GO:0043085 184 0.049
synaptic growth at neuromuscular junction GO:0051124 1 0.049
response to mechanical stimulus GO:0009612 134 0.049
nucleotide catabolic process GO:0009166 139 0.049
Rat
transmembrane transport GO:0055085 412 0.048
Yeast
blood vessel morphogenesis GO:0048514 58 0.048
response to transforming growth factor beta GO:0071559 46 0.047
gland development GO:0048732 155 0.046
negative regulation of transcription dna templated GO:0045892 116 0.046
response to external biotic stimulus GO:0043207 221 0.046
negative regulation of cellular component organization GO:0051129 83 0.045
muscle contraction GO:0006936 88 0.045
cellular response to lipid GO:0071396 201 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
regulation of cellular component biogenesis GO:0044087 86 0.044
regulation of transferase activity GO:0051338 123 0.044
regulation of transcription dna templated GO:0006355 374 0.043
positive regulation of biosynthetic process GO:0009891 319 0.043
negative regulation of cell proliferation GO:0008285 119 0.043
carboxylic acid biosynthetic process GO:0046394 83 0.042
axon development GO:0061564 96 0.042
Fly
kidney development GO:0001822 67 0.042
positive regulation of cellular component organization GO:0051130 200 0.042
positive regulation of cell differentiation GO:0045597 217 0.042
response to fluid shear stress GO:0034405 16 0.041
ribonucleoside catabolic process GO:0042454 126 0.041
Rat
purine nucleoside triphosphate catabolic process GO:0009146 122 0.041
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
carboxylic acid metabolic process GO:0019752 289 0.039
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.039
cytokine biosynthetic process GO:0042089 3 0.039
rna metabolic process GO:0016070 406 0.039
rhythmic process GO:0048511 156 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
cytokine production GO:0001816 61 0.038
regulation of protein modification process GO:0031399 194 0.038
response to wounding GO:0009611 254 0.038
dna metabolic process GO:0006259 96 0.037
cellular response to growth factor stimulus GO:0071363 162 0.037
sexual reproduction GO:0019953 148 0.037
regulation of cell migration GO:0030334 128 0.036
response to ketone GO:1901654 182 0.036
response to growth factor GO:0070848 189 0.036
cardiovascular system development GO:0072358 134 0.035
response to radiation GO:0009314 137 0.035
positive regulation of nucleoside metabolic process GO:0045979 55 0.035
response to organophosphorus GO:0046683 102 0.035
cellular component morphogenesis GO:0032989 155 0.035
Fly
cellular response to molecule of bacterial origin GO:0071219 56 0.035
regulation of protein serine threonine kinase activity GO:0071900 64 0.035
glycosyl compound catabolic process GO:1901658 126 0.035
Rat
regulation of cell differentiation GO:0045595 320 0.034
protein transmembrane transport GO:0071806 2 0.034
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
establishment of protein localization to organelle GO:0072594 44 0.034
Yeast
single organism biosynthetic process GO:0044711 342 0.034
positive regulation of neuron apoptotic process GO:0043525 33 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
collateral sprouting GO:0048668 2 0.033
bmp signaling pathway GO:0030509 4 0.033
secretion by cell GO:0032940 248 0.033
Fly
regulation of response to stress GO:0080134 126 0.033
positive regulation of nervous system development GO:0051962 178 0.033
feeding behavior GO:0007631 53 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.033
negative regulation of protein phosphorylation GO:0001933 44 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
regulation of neuron apoptotic process GO:0043523 83 0.032
negative regulation of response to stimulus GO:0048585 155 0.032
cell migration GO:0016477 197 0.032
positive regulation of apoptotic process GO:0043065 154 0.032
positive regulation of cardiac muscle contraction GO:0060452 4 0.031
ribonucleoside triphosphate metabolic process GO:0009199 141 0.031
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.031
single organism catabolic process GO:0044712 283 0.031
Rat
negative regulation of biosynthetic process GO:0009890 168 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
Rat
defense response GO:0006952 194 0.030
negative regulation of cytokine production GO:0001818 16 0.030
regulation of nucleotide catabolic process GO:0030811 65 0.030
response to ionizing radiation GO:0010212 59 0.030
behavior GO:0007610 205 0.030
nucleoside phosphate catabolic process GO:1901292 140 0.030
Rat
ribose phosphate metabolic process GO:0019693 235 0.030
Rat
secretion GO:0046903 307 0.030
Fly
response to glucocorticoid GO:0051384 223 0.029
atp catabolic process GO:0006200 54 0.029
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.029
ribonucleoside metabolic process GO:0009119 174 0.029
Rat
response to nutrient levels GO:0031667 370 0.029
cell projection morphogenesis GO:0048858 123 0.029
Fly
response to camp GO:0051591 91 0.029
positive regulation of immune system process GO:0002684 90 0.029
nucleoside triphosphate metabolic process GO:0009141 144 0.028
Rat
purine nucleoside monophosphate catabolic process GO:0009128 55 0.028
Rat
cell morphogenesis GO:0000902 142 0.028
Fly
reproduction GO:0000003 245 0.028
response to light stimulus GO:0009416 52 0.028
urogenital system development GO:0001655 78 0.028
regulation of cytokine biosynthetic process GO:0042035 3 0.027
amine metabolic process GO:0009308 38 0.027
epithelium development GO:0060429 96 0.027
response to starvation GO:0042594 59 0.027
organophosphate catabolic process GO:0046434 148 0.027
Rat
inactivation of mapk activity GO:0000188 2 0.027
protein complex biogenesis GO:0070271 263 0.026
regulation of cardiac muscle contraction GO:0055117 17 0.026
cellular chemical homeostasis GO:0055082 247 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
neuron death GO:0070997 127 0.026
cellular response to reactive oxygen species GO:0034614 55 0.026
regulation of purine nucleotide catabolic process GO:0033121 65 0.026
cellular response to cycloheximide GO:0071409 4 0.026
developmental process involved in reproduction GO:0003006 159 0.026
tissue regeneration GO:0042246 36 0.026
regulation of hormone levels GO:0010817 187 0.026
heart morphogenesis GO:0003007 3 0.025
blood circulation GO:0008015 183 0.025
dna replication GO:0006260 37 0.025
gastrulation GO:0007369 2 0.025
organ regeneration GO:0031100 101 0.025
organic acid biosynthetic process GO:0016053 83 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
cytoskeleton organization GO:0007010 111 0.025
positive regulation of cellular component movement GO:0051272 102 0.025
positive regulation of cell development GO:0010720 176 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
positive regulation of fat cell differentiation GO:0045600 2 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.024
catabolic process GO:0009056 351 0.024
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.024
regulation of neuron differentiation GO:0045664 208 0.024
small molecule biosynthetic process GO:0044283 124 0.024
cellular component movement GO:0006928 248 0.024
Fly
negative regulation of growth GO:0045926 37 0.024
circadian rhythm GO:0007623 88 0.024
response to mineralocorticoid GO:0051385 49 0.023
regulation of cell projection organization GO:0031344 175 0.023
mitochondrion organization GO:0007005 35 0.023
regulation of cell motility GO:2000145 131 0.023
de novo posttranslational protein folding GO:0051084 2 0.023
Rat
immune system process GO:0002376 204 0.023
ribonucleoside monophosphate catabolic process GO:0009158 55 0.023
Rat
renal system development GO:0072001 67 0.023
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.023
protein homooligomerization GO:0051260 91 0.022
negative regulation of protein modification process GO:0031400 52 0.022
cellular response to lipopolysaccharide GO:0071222 55 0.022
macromolecular complex assembly GO:0065003 273 0.022
protein transport GO:0015031 132 0.022
Yeast
macromolecule localization GO:0033036 252 0.022
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.022
Rat
cellular amino acid metabolic process GO:0006520 107 0.022
negative regulation of phosphorylation GO:0042326 57 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
Rat
regulation of kinase activity GO:0043549 117 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of signaling GO:0023056 270 0.021
negative regulation of neuron death GO:1901215 69 0.021
embryonic skeletal system morphogenesis GO:0048704 3 0.021
positive regulation of locomotion GO:0040017 102 0.021
regeneration GO:0031099 163 0.020
positive regulation of fibroblast proliferation GO:0048146 15 0.020
multi multicellular organism process GO:0044706 138 0.020
mesoderm development GO:0007498 2 0.020
regulation of hydrolase activity GO:0051336 143 0.020
response to axon injury GO:0048678 59 0.020
response to xenobiotic stimulus GO:0009410 23 0.020
locomotor rhythm GO:0045475 1 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
sex differentiation GO:0007548 113 0.019
placenta development GO:0001890 22 0.019
positive regulation of catabolic process GO:0009896 78 0.019
myeloid leukocyte differentiation GO:0002573 20 0.019
regulation of neuron death GO:1901214 115 0.019
myeloid cell differentiation GO:0030099 22 0.019
regulation of fat cell differentiation GO:0045598 3 0.019
nucleotide metabolic process GO:0009117 279 0.019
Rat
dendrite morphogenesis GO:0048813 43 0.019
mesenchymal cell proliferation GO:0010463 4 0.019
muscle cell proliferation GO:0033002 84 0.019
single organism cellular localization GO:1902580 102 0.019
Yeast
conditioned taste aversion GO:0001661 2 0.019
purine nucleoside catabolic process GO:0006152 124 0.018
Rat
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.018
regulation of cellular localization GO:0060341 263 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
Rat
dephosphorylation GO:0016311 98 0.018
cellular amine metabolic process GO:0044106 38 0.018
protein localization to organelle GO:0033365 57 0.018
Yeast
organic substance catabolic process GO:1901575 316 0.018
Rat
regulation of response to external stimulus GO:0032101 106 0.018
apoptotic signaling pathway GO:0097190 27 0.018
monosaccharide metabolic process GO:0005996 61 0.018
regulation of mapk cascade GO:0043408 116 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.018
response to metal ion GO:0010038 253 0.018
muscle structure development GO:0061061 87 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
homeostatic process GO:0042592 331 0.018
immune response GO:0006955 104 0.018
regulation of defense response GO:0031347 68 0.018
positive regulation of g0 to g1 transition GO:0070318 2 0.018
nucleoside monophosphate metabolic process GO:0009123 93 0.017
Rat
positive regulation of cellular catabolic process GO:0031331 71 0.017
negative regulation of cell communication GO:0010648 158 0.017
activation of cysteine type endopeptidase activity GO:0097202 4 0.017
erk1 and erk2 cascade GO:0070371 48 0.017
positive regulation of response to external stimulus GO:0032103 51 0.017
neuron projection regeneration GO:0031102 35 0.017
male gamete generation GO:0048232 99 0.017
response to dexamethasone GO:0071548 49 0.017
mitochondrial transport GO:0006839 19 0.017
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
circulatory system process GO:0003013 183 0.016
response to alkaloid GO:0043279 132 0.016
embryonic placenta development GO:0001892 1 0.016
wound healing GO:0042060 122 0.016
axon regeneration GO:0031103 28 0.016
protein import GO:0017038 37 0.016
negative regulation of signaling GO:0023057 157 0.016
regulation of cellular response to stress GO:0080135 49 0.016
response to hexose GO:0009746 144 0.016
lipid metabolic process GO:0006629 283 0.016
response to peptide hormone GO:0043434 278 0.016
response to lipopolysaccharide GO:0032496 191 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
regulation of nucleoside metabolic process GO:0009118 66 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
regulation of blood circulation GO:1903522 110 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
regulation of cell growth GO:0001558 85 0.015
response to acid chemical GO:0001101 222 0.015
dendrite development GO:0016358 72 0.015
developmental growth involved in morphogenesis GO:0060560 33 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of dna metabolic process GO:0051052 60 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
Rat
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 1 0.015
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.015
regulation of peptidase activity GO:0052547 55 0.015
lens fiber cell differentiation GO:0070306 3 0.015
negative regulation of erk1 and erk2 cascade GO:0070373 9 0.015
single organism behavior GO:0044708 130 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regulation of neuron projection development GO:0010975 161 0.015
sensory organ development GO:0007423 74 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
microtubule based process GO:0007017 36 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
response to fatty acid GO:0070542 65 0.014
response to gamma radiation GO:0010332 24 0.014
positive regulation of atpase activity GO:0032781 6 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
response to corticosterone GO:0051412 40 0.014
ras protein signal transduction GO:0007265 29 0.014
response to glucose GO:0009749 136 0.014
head development GO:0060322 247 0.014
myosin filament assembly GO:0031034 1 0.014
cytokine mediated signaling pathway GO:0019221 43 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.013
heart contraction GO:0060047 57 0.013
regulation of jnk cascade GO:0046328 19 0.013
negative regulation of signal transduction GO:0009968 83 0.013
establishment of protein localization GO:0045184 141 0.013
Yeast
regulation of locomotion GO:0040012 148 0.013
vesicle mediated transport GO:0016192 181 0.013
Fly
ossification GO:0001503 70 0.013
proteolysis GO:0006508 175 0.013
spermatogenesis GO:0007283 99 0.013
developmental growth GO:0048589 100 0.013
response to cycloheximide GO:0046898 6 0.013
oxoacid metabolic process GO:0043436 290 0.013
cellular response to acid chemical GO:0071229 75 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
ovulation GO:0030728 17 0.013
cellular macromolecule localization GO:0070727 122 0.013
Yeast
neuron projection development GO:0031175 273 0.012
Fly
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
regulation of map kinase activity GO:0043405 53 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
nitrogen compound transport GO:0071705 229 0.012
positive regulation of blood circulation GO:1903524 65 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
cell cell signaling GO:0007267 335 0.012
Fly
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
regulation of growth GO:0040008 105 0.012
heart process GO:0003015 57 0.012
transmission of nerve impulse GO:0019226 42 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
central nervous system development GO:0007417 311 0.012
fibroblast proliferation GO:0048144 22 0.012
positive regulation of immunoglobulin production GO:0002639 4 0.012
positive regulation of leukocyte differentiation GO:1902107 13 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of myeloid leukocyte differentiation GO:0002761 12 0.012
protein dephosphorylation GO:0006470 38 0.012
eye development GO:0001654 50 0.012
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.012
regulation of protein localization GO:0032880 81 0.012
regulation of secretion by cell GO:1903530 208 0.012
cellular response to peptide GO:1901653 133 0.012
carbohydrate metabolic process GO:0005975 130 0.012
small gtpase mediated signal transduction GO:0007264 36 0.011

Hspa1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.064
sensory system disease DOID:0050155 0 0.062
cardiovascular system disease DOID:1287 0 0.041
myopathy DOID:423 0 0.036
muscular disease DOID:0080000 0 0.036
musculoskeletal system disease DOID:17 0 0.036
muscle tissue disease DOID:66 0 0.036
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
heart disease DOID:114 0 0.017
cardiomyopathy DOID:0050700 0 0.017
gastrointestinal system cancer DOID:3119 0 0.013