Rattus norvegicus

6 known processes

Hspb7

heat shock protein family, member 7 (cardiovascular)

(Aliases: Hsp25-2)

Hspb7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex assembly GO:0006461 263 0.248
protein complex biogenesis GO:0070271 263 0.245
protein complex subunit organization GO:0071822 302 0.202
muscle system process GO:0003012 115 0.190
blood circulation GO:0008015 183 0.170
regulation of cellular component organization GO:0051128 368 0.164
cellular component biogenesis GO:0044085 368 0.155
striated muscle contraction GO:0006941 44 0.154
cellular component movement GO:0006928 248 0.146
heart contraction GO:0060047 57 0.143
cardiac muscle contraction GO:0060048 27 0.131
cellular response to mechanical stimulus GO:0071260 48 0.128
cellular component morphogenesis GO:0032989 155 0.128
macromolecular complex assembly GO:0065003 273 0.126
muscle contraction GO:0006936 88 0.120
circulatory system process GO:0003013 183 0.117
anatomical structure morphogenesis GO:0009653 298 0.110
response to nutrient GO:0007584 248 0.108
regulation of multicellular organismal development GO:2000026 376 0.107
cellular component assembly GO:0022607 360 0.102
macromolecular complex subunit organization GO:0043933 339 0.091
response to wounding GO:0009611 254 0.088
chemical homeostasis GO:0048878 292 0.086
inflammatory response GO:0006954 150 0.077
metal ion homeostasis GO:0055065 186 0.076
regulation of system process GO:0044057 208 0.075
regulation of molecular function GO:0065009 398 0.073
response to mechanical stimulus GO:0009612 134 0.073
cellular metal ion homeostasis GO:0006875 172 0.072
defense response GO:0006952 194 0.071
regulation of blood circulation GO:1903522 110 0.070
cellular homeostasis GO:0019725 252 0.068
homeostatic process GO:0042592 331 0.063
ion homeostasis GO:0050801 212 0.062
actin mediated cell contraction GO:0070252 12 0.061
muscle tissue development GO:0060537 58 0.057
muscle structure development GO:0061061 87 0.054
neuron projection morphogenesis GO:0048812 122 0.054
cellular calcium ion homeostasis GO:0006874 160 0.053
heart process GO:0003015 57 0.053
regulation of muscle contraction GO:0006937 53 0.051
cellular cation homeostasis GO:0030003 180 0.049
response to extracellular stimulus GO:0009991 380 0.049
actin filament based movement GO:0030048 16 0.048
divalent inorganic cation homeostasis GO:0072507 165 0.046
cell projection organization GO:0030030 302 0.046
positive regulation of cell communication GO:0010647 271 0.045
cardiac muscle cell development GO:0055013 16 0.044
regulation of muscle system process GO:0090257 79 0.043
positive regulation of response to stimulus GO:0048584 285 0.043
actin filament based process GO:0030029 86 0.041
regulation of cell projection organization GO:0031344 175 0.041
response to heat GO:0009408 60 0.041
cardiac myofibril assembly GO:0055003 1 0.041
intracellular signal transduction GO:0035556 314 0.040
cation transmembrane transport GO:0098655 263 0.038
cell part morphogenesis GO:0032990 123 0.038
organelle organization GO:0006996 266 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
cytoskeleton organization GO:0007010 111 0.036
regulation of catalytic activity GO:0050790 304 0.036
muscle cell proliferation GO:0033002 84 0.035
establishment of tissue polarity GO:0007164 2 0.034
response to vitamin GO:0033273 131 0.034
regulation of heart contraction GO:0008016 48 0.033
cell projection morphogenesis GO:0048858 123 0.032
positive regulation of developmental process GO:0051094 283 0.032
heart morphogenesis GO:0003007 3 0.032
positive regulation of nervous system development GO:0051962 178 0.031
cardiac muscle tissue morphogenesis GO:0055008 1 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
cardiac conduction GO:0061337 2 0.031
schwann cell migration GO:0036135 2 0.030
potassium ion transmembrane transport GO:0071805 71 0.030
cellular response to abiotic stimulus GO:0071214 85 0.030
inorganic cation transmembrane transport GO:0098662 202 0.030
response to biotic stimulus GO:0009607 226 0.030
positive regulation of catalytic activity GO:0043085 184 0.029
cellular chemical homeostasis GO:0055082 247 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
cell growth GO:0016049 104 0.029
regulation of cellular component biogenesis GO:0044087 86 0.029
regulation of neurogenesis GO:0050767 247 0.029
striated muscle tissue development GO:0014706 58 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
regulation of neuron differentiation GO:0045664 208 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
regulation of establishment of planar polarity GO:0090175 2 0.027
actin cytoskeleton organization GO:0030036 73 0.027
response to muscle stretch GO:0035994 2 0.026
cardiac cell development GO:0055006 16 0.026
positive regulation of molecular function GO:0044093 230 0.026
response to nutrient levels GO:0031667 370 0.026
cardiovascular system development GO:0072358 134 0.026
neuron projection development GO:0031175 273 0.025
response to ionizing radiation GO:0010212 59 0.025
calcium ion homeostasis GO:0055074 162 0.025
response to molecule of bacterial origin GO:0002237 194 0.024
establishment of planar polarity GO:0001736 1 0.024
single organism organelle organization GO:1902589 180 0.024
cellular potassium ion transport GO:0071804 72 0.023
cellular ion homeostasis GO:0006873 184 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
growth GO:0040007 165 0.023
regulation of cell development GO:0060284 263 0.023
neuron development GO:0048666 286 0.022
positive regulation of signal transduction GO:0009967 175 0.022
locomotion GO:0040011 237 0.022
regulation of body fluid levels GO:0050878 90 0.021
regulation of striated muscle contraction GO:0006942 21 0.021
response to peptide hormone GO:0043434 278 0.021
positive regulation of cell development GO:0010720 176 0.021
cardiac ventricle development GO:0003231 1 0.021
lipid metabolic process GO:0006629 283 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of neuron projection development GO:0010975 161 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
cell motility GO:0048870 202 0.020
cell morphogenesis GO:0000902 142 0.020
muscle organ development GO:0007517 50 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
protein polymerization GO:0051258 22 0.019
wound healing GO:0042060 122 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
cellular protein complex assembly GO:0043623 44 0.019
regulation of programmed cell death GO:0043067 341 0.019
circulatory system development GO:0072359 134 0.018
cardiac chamber development GO:0003205 1 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
transmembrane transport GO:0055085 412 0.018
muscle cell differentiation GO:0042692 52 0.017
muscle cell development GO:0055001 26 0.017
immune system process GO:0002376 204 0.017
response to other organism GO:0051707 220 0.017
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.017
response to decreased oxygen levels GO:0036293 237 0.017
striated muscle cell development GO:0055002 26 0.017
regulation of hormone levels GO:0010817 187 0.017
reproductive system development GO:0061458 128 0.017
metal ion transport GO:0030001 289 0.017
cellular response to lipid GO:0071396 201 0.017
regulation of membrane potential GO:0042391 110 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
cation homeostasis GO:0055080 195 0.016
cation transport GO:0006812 382 0.016
axonogenesis GO:0007409 71 0.016
response to bacterium GO:0009617 200 0.016
neuron death GO:0070997 127 0.016
potassium ion transport GO:0006813 97 0.016
negative regulation of programmed cell death GO:0043069 183 0.015
multicellular organismal movement GO:0050879 17 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
actomyosin structure organization GO:0031032 22 0.015
regulation of cardiac muscle contraction GO:0055117 17 0.015
single organism biosynthetic process GO:0044711 342 0.015
localization of cell GO:0051674 202 0.015
rna biosynthetic process GO:0032774 380 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
response to peptide GO:1901652 292 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
skeletal muscle tissue development GO:0007519 31 0.014
protein homooligomerization GO:0051260 91 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of membrane repolarization GO:0060306 1 0.014
protein oligomerization GO:0051259 191 0.014
regulation of cell growth GO:0001558 85 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
cellular amine metabolic process GO:0044106 38 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
negative regulation of cell communication GO:0010648 158 0.013
neuron differentiation GO:0030182 368 0.013
ventricular cardiac muscle cell action potential GO:0086005 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 17 0.013
tissue development GO:0009888 252 0.013
cardiocyte differentiation GO:0035051 22 0.013
positive regulation of cellular component organization GO:0051130 200 0.012
regulation of apoptotic process GO:0042981 335 0.012
regulation of protein kinase activity GO:0045859 105 0.012
anterior posterior pattern specification GO:0009952 1 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
ras protein signal transduction GO:0007265 29 0.012
apoptotic process GO:0006915 381 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of schwann cell migration GO:1900147 2 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of cellular component movement GO:0051270 150 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of ion transport GO:0043269 245 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of growth GO:0040008 105 0.011
cellular response to external stimulus GO:0071496 118 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
multicellular organismal signaling GO:0035637 44 0.011
response to hypoxia GO:0001666 231 0.011
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
behavior GO:0007610 205 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
positive regulation of signaling GO:0023056 270 0.011
epithelium development GO:0060429 96 0.011
negative regulation of metabolic process GO:0009892 331 0.011
skeletal muscle organ development GO:0060538 33 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of cardiac muscle cell contraction GO:0086004 11 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of nervous system development GO:0051960 264 0.011
regulation of anatomical structure size GO:0090066 135 0.011
amine metabolic process GO:0009308 38 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
epithelial cell differentiation GO:0030855 71 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
protein maturation GO:0051604 68 0.010
response to activity GO:0014823 73 0.010
muscle tissue morphogenesis GO:0060415 1 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
negative regulation of heart growth GO:0061117 3 0.010
multi organism reproductive process GO:0044703 262 0.010
nucleotide catabolic process GO:0009166 139 0.010

Hspb7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.813
cardiovascular system disease DOID:1287 0 0.813
heart disease DOID:114 0 0.436
myopathy DOID:423 0 0.407
musculoskeletal system disease DOID:17 0 0.407
muscle tissue disease DOID:66 0 0.407
muscular disease DOID:0080000 0 0.407
cardiomyopathy DOID:0050700 0 0.395
intrinsic cardiomyopathy DOID:0060036 0 0.164
muscular dystrophy DOID:9884 0 0.029
hypertrophic cardiomyopathy DOID:11984 0 0.027
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
congenital heart disease DOID:1682 0 0.022
heart septal defect DOID:1681 0 0.022
dilated cardiomyopathy DOID:12930 0 0.021
eye disease DOID:5614 0 0.011
retinal disease DOID:5679 0 0.011