|
|
synaptic transmission
|
GO:0007268 |
235 |
0.899
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.896
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.835
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.833
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.820
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.760
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.726
|
Rat |
|
|
neuropeptide signaling pathway
|
GO:0007218 |
29 |
0.637
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.634
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.565
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.532
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.515
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.508
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.499
|
Rat |
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
4 |
0.484
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.483
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.477
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.471
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.465
|
Rat |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.463
|
Rat |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.459
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.454
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.441
|
Rat |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.431
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.431
|
Rat |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.417
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.384
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.383
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.367
|
Rat |
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.358
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.348
|
Rat |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.345
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.343
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.341
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.333
|
Rat |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.333
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.331
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.325
|
Rat |
|
|
adenylate cyclase inhibiting opioid receptor signaling pathway
|
GO:0031635 |
2 |
0.324
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.320
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.313
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.310
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.293
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.289
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
3 |
0.288
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.271
|
Rat |
|
|
neurological system process
|
GO:0050877 |
219 |
0.269
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.268
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.265
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.265
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.264
|
Rat |
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.262
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.260
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.260
|
Rat |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.259
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.252
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.251
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.251
|
Rat |
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.248
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
24 |
0.247
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.244
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.238
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.236
|
Rat |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.234
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.233
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.231
|
Rat |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.228
|
Rat |
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.226
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.226
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.225
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.220
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.217
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.215
|
Rat |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.212
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.209
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.207
|
Rat |
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.207
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.203
|
|
|
|
amino acid transport
|
GO:0006865 |
70 |
0.202
|
|
|
|
acid secretion
|
GO:0046717 |
48 |
0.202
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.197
|
Rat |
|
|
single organism behavior
|
GO:0044708 |
130 |
0.195
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
26 |
0.195
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.195
|
Rat |
|
|
sensory perception
|
GO:0007600 |
101 |
0.195
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.194
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.193
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.191
|
Rat |
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.189
|
Rat |
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.187
|
Rat |
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.187
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.181
|
Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.179
|
Rat |
|
|
locomotion
|
GO:0040011 |
237 |
0.178
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.177
|
|
|
|
response to cocaine
|
GO:0042220 |
39 |
0.177
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.174
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.174
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.171
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.170
|
Rat |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.169
|
Rat |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.167
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.166
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.162
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.162
|
Rat |
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.162
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.161
|
Rat |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.161
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.154
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.154
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.153
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.152
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.151
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.151
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.150
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.148
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.145
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.143
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.141
|
Rat |
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.141
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.139
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.139
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.138
|
Rat |
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.138
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.138
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.138
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.137
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.136
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.135
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.133
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.133
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.132
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.130
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.128
|
Rat |
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.127
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
18 |
0.127
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.126
|
Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.126
|
Rat |
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.125
|
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
4 |
0.125
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.123
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.123
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
3 |
0.122
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.122
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.121
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
77 |
0.121
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.120
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
43 |
0.119
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.119
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.116
|
Rat |
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.115
|
|
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.115
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.112
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.112
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.112
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
35 |
0.111
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.111
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.110
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.109
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.108
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.107
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.107
|
|
|
|
learning
|
GO:0007612 |
33 |
0.106
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.106
|
Rat |
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.106
|
Rat |
|
|
defense response
|
GO:0006952 |
194 |
0.106
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.106
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.105
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.105
|
Rat |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.105
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.104
|
Rat |
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.104
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.103
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.103
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.103
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.102
|
Rat |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.102
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.102
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.101
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.100
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.100
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.098
|
Rat |
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.098
|
Rat |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.097
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.097
|
Rat |
|
|
regulation of excretion
|
GO:0044062 |
21 |
0.096
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.095
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.095
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.095
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.095
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.094
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.094
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.093
|
|
|
|
calcium ion import
|
GO:0070509 |
22 |
0.090
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.089
|
|
|
|
peristalsis
|
GO:0030432 |
2 |
0.089
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.089
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.088
|
|
|
|
choline transport
|
GO:0015871 |
4 |
0.088
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
52 |
0.088
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.088
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.088
|
Rat |
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
18 |
0.087
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.087
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.087
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.086
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.086
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.086
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.084
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.084
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.083
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.083
|
|
|
|
response to nicotine
|
GO:0035094 |
51 |
0.082
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
42 |
0.082
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.082
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.082
|
|
|
|
head development
|
GO:0060322 |
247 |
0.082
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
55 |
0.082
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.082
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.080
|
Rat |
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.079
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.079
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.078
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.078
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
3 |
0.078
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.077
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.077
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.077
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.077
|
Rat |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
36 |
0.076
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.076
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.075
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.075
|
Rat |
|
|
regulation of heart rate
|
GO:0002027 |
16 |
0.074
|
Rat |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.074
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.073
|
Rat |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
68 |
0.073
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.073
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
29 |
0.072
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
51 |
0.072
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.072
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.071
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.071
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.071
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.070
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.070
|
|
|
|
telencephalon development
|
GO:0021537 |
62 |
0.070
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.070
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.070
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.070
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.069
|
|
|
|
response to fatty acid
|
GO:0070542 |
65 |
0.069
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
48 |
0.068
|
|
|
|
gamma aminobutyric acid transport
|
GO:0015812 |
8 |
0.068
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.068
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.068
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.068
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.067
|
|
|
|
vasoconstriction
|
GO:0042310 |
54 |
0.067
|
Rat |
|
|
kidney development
|
GO:0001822 |
67 |
0.067
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.066
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
6 |
0.066
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.066
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.065
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.065
|
Rat |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.065
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.065
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.065
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
33 |
0.064
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.064
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.064
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.062
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.062
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.062
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.062
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.062
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.062
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.062
|
|
|
|
growth
|
GO:0040007 |
165 |
0.062
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.061
|
|
|
|
dicarboxylic acid transport
|
GO:0006835 |
34 |
0.061
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.061
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.061
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.061
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.060
|
Rat |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.060
|
Rat |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.060
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.060
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.060
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.059
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.059
|
|
|
|
saliva secretion
|
GO:0046541 |
3 |
0.059
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.059
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
83 |
0.059
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.058
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.058
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.058
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.058
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
28 |
0.058
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.058
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.057
|
Rat |
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.057
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.057
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.056
|
Rat |
|
|
neuron death
|
GO:0070997 |
127 |
0.056
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
10 |
0.055
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.055
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.055
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.052
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.052
|
|
|
|
aging
|
GO:0007568 |
241 |
0.052
|
Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.052
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.051
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
87 |
0.051
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
47 |
0.051
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.050
|
|
|
|
hormone secretion
|
GO:0046879 |
115 |
0.050
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.049
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.049
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.049
|
Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.049
|
|
|
|
catecholamine transport
|
GO:0051937 |
37 |
0.048
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.048
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.048
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.048
|
Rat |
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.048
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.047
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.047
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
33 |
0.047
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
25 |
0.047
|
|
|
|
protein homooligomerization
|
GO:0051260 |
91 |
0.047
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.047
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.046
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.046
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.046
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.046
|
|
|
|
memory
|
GO:0007613 |
54 |
0.046
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.045
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.045
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.045
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
72 |
0.044
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.044
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.044
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
70 |
0.044
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
29 |
0.043
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.043
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.042
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.042
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.042
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.042
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.042
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.041
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.041
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.041
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.041
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.041
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.041
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.040
|
|
|
|
negative regulation of camp metabolic process
|
GO:0030815 |
14 |
0.040
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.040
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.040
|
|
|
|
positive regulation of saliva secretion
|
GO:0046878 |
3 |
0.040
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.039
|
Rat |
|
|
smooth muscle cell proliferation
|
GO:0048659 |
77 |
0.039
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.039
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.038
|
|
|
|
negative regulation of adenylate cyclase activity
|
GO:0007194 |
7 |
0.038
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.037
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.037
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.037
|
|
|
|
associative learning
|
GO:0008306 |
19 |
0.037
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
25 |
0.037
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
42 |
0.037
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.037
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.036
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
51 |
0.036
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.036
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.036
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.036
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.035
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.035
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.035
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.035
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
51 |
0.035
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.035
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.035
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.035
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
87 |
0.035
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.034
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.034
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.034
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.034
|
|
|
|
oxidation reduction process
|
GO:0055114 |
304 |
0.034
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.034
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
82 |
0.034
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.034
|
Rat |
|
|
positive regulation of lyase activity
|
GO:0051349 |
15 |
0.034
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.034
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.034
|
|
|
|
synapse assembly
|
GO:0007416 |
29 |
0.034
|
|
|
|
regulation of amino acid transport
|
GO:0051955 |
25 |
0.033
|
|
|
|
angiotensin mediated drinking behavior
|
GO:0003051 |
2 |
0.033
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.033
|
|
|
|
glutamate secretion
|
GO:0014047 |
19 |
0.033
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.033
|
Rat |
|
|
positive regulation of the force of heart contraction by epinephrine
|
GO:0003059 |
1 |
0.033
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
21 |
0.033
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.033
|
Rat |
|
|
peptide secretion
|
GO:0002790 |
86 |
0.033
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.033
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.032
|
|
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.032
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.032
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.032
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.032
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.032
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.032
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.032
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
26 |
0.032
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.032
|
Rat |
|
|
regulation of sensory perception
|
GO:0051931 |
29 |
0.032
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
19 |
0.031
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.031
|
|
|
|
long chain fatty acid transport
|
GO:0015909 |
14 |
0.031
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
99 |
0.031
|
|
|
|
epithelial cell migration
|
GO:0010631 |
19 |
0.031
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.031
|
Rat |
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.031
|
|
|
|
male gonad development
|
GO:0008584 |
59 |
0.031
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.030
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
30 |
0.030
|
Rat |
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
10 |
0.030
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.030
|
Rat |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
67 |
0.030
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.030
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.030
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
56 |
0.030
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.030
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
80 |
0.030
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.029
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.029
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.029
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.029
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.029
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.029
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.029
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.029
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.029
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.029
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.029
|
|
|
|
behavioral response to cocaine
|
GO:0048148 |
6 |
0.029
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.029
|
|
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.029
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.028
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.028
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.028
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.028
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.028
|
|
|
|
positive regulation of appetite
|
GO:0032100 |
2 |
0.028
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.028
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.028
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.028
|
|
|
|
ovulation cycle
|
GO:0042698 |
67 |
0.028
|
|
|
|
renal system development
|
GO:0072001 |
67 |
0.028
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.028
|
|
|
|
regulation of long term synaptic potentiation
|
GO:1900271 |
5 |
0.028
|
|
|
|
positive regulation of response to food
|
GO:0032097 |
3 |
0.027
|
|
|
|
gamma aminobutyric acid secretion
|
GO:0014051 |
6 |
0.027
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.027
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
21 |
0.027
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.027
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.027
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.027
|
|
|
|
limbic system development
|
GO:0021761 |
38 |
0.027
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.026
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.026
|
Rat |
|
|
cellular response to acid chemical
|
GO:0071229 |
75 |
0.026
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
71 |
0.026
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.026
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.026
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
21 |
0.026
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.026
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.026
|
Rat |
|
|
fertilization
|
GO:0009566 |
3 |
0.026
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.026
|
|
|
|
negative regulation of cyclase activity
|
GO:0031280 |
7 |
0.026
|
|
