Rattus norvegicus

0 known processes

Htra3

HtrA serine peptidase 3

(Aliases: RGD1308120)

Htra3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
kidney development GO:0001822 67 0.210
renal system development GO:0072001 67 0.087
positive regulation of response to external stimulus GO:0032103 51 0.074
reproductive process GO:0022414 372 0.070
multi organism reproductive process GO:0044703 262 0.067
tissue development GO:0009888 252 0.064
head development GO:0060322 247 0.062
multi multicellular organism process GO:0044706 138 0.061
cellular response to hormone stimulus GO:0032870 247 0.059
response to dexamethasone GO:0071548 49 0.057
rna biosynthetic process GO:0032774 380 0.049
aging GO:0007568 241 0.049
cell cell signaling GO:0007267 335 0.048
behavior GO:0007610 205 0.047
response to wounding GO:0009611 254 0.045
regulation of rna metabolic process GO:0051252 391 0.044
Mouse
response to corticosteroid GO:0031960 235 0.043
central nervous system development GO:0007417 311 0.042
transcription dna templated GO:0006351 377 0.039
response to oxygen levels GO:0070482 265 0.039
regeneration GO:0031099 163 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
oxoacid metabolic process GO:0043436 290 0.037
brain development GO:0007420 247 0.037
female pregnancy GO:0007565 122 0.037
positive regulation of cell proliferation GO:0008284 249 0.036
Rat
anatomical structure morphogenesis GO:0009653 298 0.036
Rat
organ regeneration GO:0031100 101 0.035
cellular component movement GO:0006928 248 0.034
catabolic process GO:0009056 351 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
ossification GO:0001503 70 0.034
response to nutrient GO:0007584 248 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
multicellular organism reproduction GO:0032504 233 0.030
regulation of defense response GO:0031347 68 0.030
Rat
negative regulation of cell death GO:0060548 229 0.030
Rat
regulation of immune system process GO:0002682 123 0.029
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
response to hypoxia GO:0001666 231 0.029
regulation of response to external stimulus GO:0032101 106 0.029
Rat
regulation of cellular localization GO:0060341 263 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
positive regulation of transport GO:0051050 245 0.027
cardiovascular system development GO:0072358 134 0.027
reproduction GO:0000003 245 0.027
regulation of multicellular organismal development GO:2000026 376 0.026
positive regulation of gene expression GO:0010628 244 0.026
chemical homeostasis GO:0048878 292 0.025
response to decreased oxygen levels GO:0036293 237 0.025
rna metabolic process GO:0016070 406 0.024
single organism biosynthetic process GO:0044711 342 0.024
regulation of transcription dna templated GO:0006355 374 0.024
Mouse
positive regulation of signaling GO:0023056 270 0.024
cellular homeostasis GO:0019725 252 0.024
protein homooligomerization GO:0051260 91 0.024
single organism catabolic process GO:0044712 283 0.024
organic substance catabolic process GO:1901575 316 0.023
cellular amine metabolic process GO:0044106 38 0.023
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.023
response to glucocorticoid GO:0051384 223 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
homeostatic process GO:0042592 331 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of ion transport GO:0043269 245 0.022
regulation of cellular component movement GO:0051270 150 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
vasculature development GO:0001944 70 0.022
response to external biotic stimulus GO:0043207 221 0.022
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of inflammatory response GO:0050727 48 0.022
positive regulation of cell motility GO:2000147 97 0.021
cell migration GO:0016477 197 0.021
cell migration involved in kidney development GO:0035787 2 0.021
response to estrogen GO:0043627 232 0.021
positive regulation of developmental process GO:0051094 283 0.021
single organism reproductive process GO:0044702 297 0.021
organophosphate metabolic process GO:0019637 370 0.020
metal ion homeostasis GO:0055065 186 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
Mouse
positive regulation of response to stimulus GO:0048584 285 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
Mouse
amine metabolic process GO:0009308 38 0.019
regulation of body fluid levels GO:0050878 90 0.019
cellular response to lipid GO:0071396 201 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
response to peptide hormone GO:0043434 278 0.019
regulation of cell motility GO:2000145 131 0.019
regulation of programmed cell death GO:0043067 341 0.019
Rat
positive regulation of leukocyte migration GO:0002687 21 0.018
regulation of blood pressure GO:0008217 83 0.018
response to peptide GO:1901652 292 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
response to metal ion GO:0010038 253 0.018
positive regulation of cell migration GO:0030335 96 0.018
positive regulation of locomotion GO:0040017 102 0.018
positive regulation of cellular component movement GO:0051272 102 0.018
response to extracellular stimulus GO:0009991 380 0.018
cellular component biogenesis GO:0044085 368 0.018
apoptotic process GO:0006915 381 0.018
Rat
cellular response to organic cyclic compound GO:0071407 202 0.018
cellular ketone metabolic process GO:0042180 51 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
positive regulation of metanephros development GO:0072216 2 0.018
cellular catabolic process GO:0044248 295 0.018
response to insulin GO:0032868 133 0.017
male gonad development GO:0008584 59 0.017
regulation of response to stress GO:0080134 126 0.017
Rat
negative regulation of programmed cell death GO:0043069 183 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
blood circulation GO:0008015 183 0.016
regulation of response to wounding GO:1903034 69 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
response to retinoic acid GO:0032526 63 0.016
negative regulation of signaling GO:0023057 157 0.016
Mouse
programmed cell death GO:0012501 392 0.016
Rat
positive regulation of cell development GO:0010720 176 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
cellular chemical homeostasis GO:0055082 247 0.016
regulation of vasculature development GO:1901342 44 0.016
cellular response to alcohol GO:0097306 87 0.016
response to inorganic substance GO:0010035 377 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
cellular response to peptide GO:1901653 133 0.016
cellular ion homeostasis GO:0006873 184 0.016
feeding behavior GO:0007631 53 0.016
response to hexose GO:0009746 144 0.016
cellular response to acid chemical GO:0071229 75 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
response to estradiol GO:0032355 164 0.015
circulatory system process GO:0003013 183 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
regulation of kinase activity GO:0043549 117 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regulation of synaptic transmission GO:0050804 141 0.015
inflammatory response GO:0006954 150 0.015
positive regulation of inflammatory response GO:0050729 24 0.015
development of primary sexual characteristics GO:0045137 107 0.015
anion transport GO:0006820 178 0.015
defense response GO:0006952 194 0.015
Rat
regulation of phosphorylation GO:0042325 248 0.015
response to growth factor GO:0070848 189 0.015
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.015
sexual reproduction GO:0019953 148 0.015
leukocyte migration GO:0050900 38 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
circulatory system development GO:0072359 134 0.014
odontogenesis GO:0042476 32 0.014
Rat
urinary bladder smooth muscle contraction GO:0014832 4 0.014
cellular cation homeostasis GO:0030003 180 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
organic acid biosynthetic process GO:0016053 83 0.014
response to lipopolysaccharide GO:0032496 191 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
artery development GO:0060840 3 0.014
response to mechanical stimulus GO:0009612 134 0.014
negative regulation of gene expression GO:0010629 199 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
Mouse
negative regulation of metabolic process GO:0009892 331 0.014
response to carbohydrate GO:0009743 183 0.013
positive regulation of hormone secretion GO:0046887 65 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
coronary vasculature morphogenesis GO:0060977 3 0.013
organic acid metabolic process GO:0006082 292 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
reproductive system development GO:0061458 128 0.013
cation homeostasis GO:0055080 195 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
tolerance induction to nonself antigen GO:0002462 2 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
Mouse
vasoconstriction GO:0042310 54 0.013
vascular process in circulatory system GO:0003018 96 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of signal transduction GO:0009966 318 0.013
Mouse
synaptic transmission GO:0007268 235 0.013
urogenital system development GO:0001655 78 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
transmission of nerve impulse GO:0019226 42 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
appendage morphogenesis GO:0035107 4 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
response to acid chemical GO:0001101 222 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regulation of leukocyte migration GO:0002685 24 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
male sex differentiation GO:0046661 64 0.012
connective tissue development GO:0061448 33 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
nucleic acid templated transcription GO:0097659 379 0.012
immune system process GO:0002376 204 0.012
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
comma shaped body morphogenesis GO:0072049 2 0.012
response to glucose GO:0009749 136 0.012
positive regulation of defense response GO:0031349 37 0.011
negative regulation of cell communication GO:0010648 158 0.011
Mouse
tissue remodeling GO:0048771 40 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of membrane potential GO:0042391 110 0.011
regulation of system process GO:0044057 208 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cell motility GO:0048870 202 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Mouse Rat
neurological system process GO:0050877 219 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
secretion GO:0046903 307 0.011
lipid metabolic process GO:0006629 283 0.011
Rat
hormone metabolic process GO:0042445 69 0.011
positive regulation of nervous system development GO:0051962 178 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of secretion by cell GO:1903530 208 0.011
response to cytokine GO:0034097 215 0.011
response to activity GO:0014823 73 0.011
cellular component assembly GO:0022607 360 0.011
regulation of protein metabolic process GO:0051246 289 0.011
regulation of cell migration GO:0030334 128 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
regulation of angiogenesis GO:0045765 39 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
macromolecular complex assembly GO:0065003 273 0.010
regulation of blood vessel endothelial cell migration GO:0043535 4 0.010
gamete generation GO:0007276 124 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
kidney vasculature development GO:0061440 6 0.010
blood vessel development GO:0001568 69 0.010
regulation of cell proliferation GO:0042127 359 0.010
Rat
male gamete generation GO:0048232 99 0.010

Htra3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.101
musculoskeletal system disease DOID:17 0 0.101
nervous system disease DOID:863 0 0.050
bone disease DOID:0080001 0 0.021
connective tissue disease DOID:65 0 0.021
sensory system disease DOID:0050155 0 0.013
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
retinal disease DOID:5679 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011