Rattus norvegicus

0 known processes

Ica1l

islet cell autoantigen 1-like

Ica1l biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound biosynthetic process GO:1901566 167 0.265
transmembrane transport GO:0055085 412 0.222
ion transmembrane transport GO:0034220 365 0.201
cation transmembrane transport GO:0098655 263 0.183
intracellular signal transduction GO:0035556 314 0.147
regulation of ion transmembrane transport GO:0034765 121 0.139
sodium ion transport GO:0006814 82 0.134
regulation of molecular function GO:0065009 398 0.134
Rat
inorganic ion transmembrane transport GO:0098660 229 0.130
single organism biosynthetic process GO:0044711 342 0.124
cell cell signaling GO:0007267 335 0.113
inorganic cation transmembrane transport GO:0098662 202 0.108
regulation of multicellular organismal development GO:2000026 376 0.106
macromolecule localization GO:0033036 252 0.103
divalent inorganic cation homeostasis GO:0072507 165 0.101
cation transport GO:0006812 382 0.096
nucleoside phosphate metabolic process GO:0006753 283 0.095
organophosphate biosynthetic process GO:0090407 143 0.090
regulation of ion transmembrane transporter activity GO:0032412 48 0.080
secretion GO:0046903 307 0.080
positive regulation of multicellular organismal process GO:0051240 387 0.077
protein complex biogenesis GO:0070271 263 0.075
secretion by cell GO:0032940 248 0.070
regulation of cellular localization GO:0060341 263 0.068
metal ion transport GO:0030001 289 0.067
positive regulation of developmental process GO:0051094 283 0.067
organophosphate metabolic process GO:0019637 370 0.065
cellular component biogenesis GO:0044085 368 0.064
g protein coupled receptor signaling pathway GO:0007186 242 0.064
positive regulation of signaling GO:0023056 270 0.062
regulation of transmembrane transport GO:0034762 122 0.060
nucleotide metabolic process GO:0009117 279 0.058
positive regulation of cell differentiation GO:0045597 217 0.057
regulation of cell differentiation GO:0045595 320 0.057
response to inorganic substance GO:0010035 377 0.057
cation homeostasis GO:0055080 195 0.056
purine ribonucleotide metabolic process GO:0009150 227 0.055
camp metabolic process GO:0046058 63 0.055
cellular component assembly GO:0022607 360 0.055
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.055
purine containing compound metabolic process GO:0072521 253 0.055
regulation of membrane potential GO:0042391 110 0.055
cellular metal ion homeostasis GO:0006875 172 0.054
protein complex assembly GO:0006461 263 0.053
chemical homeostasis GO:0048878 292 0.052
protein phosphorylation GO:0006468 345 0.052
multicellular organismal reproductive process GO:0048609 233 0.052
ribose phosphate metabolic process GO:0019693 235 0.051
regulation of transmembrane transporter activity GO:0022898 49 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.049
protein complex subunit organization GO:0071822 302 0.045
macromolecular complex assembly GO:0065003 273 0.044
fat cell proliferation GO:0070341 2 0.043
regulation of ion transport GO:0043269 245 0.043
protein heterooligomerization GO:0051291 89 0.043
metal ion homeostasis GO:0055065 186 0.043
apoptotic process GO:0006915 381 0.043
response to metal ion GO:0010038 253 0.042
regulation of synaptic transmission GO:0050804 141 0.042
ion homeostasis GO:0050801 212 0.042
reproductive process GO:0022414 372 0.042
neuromuscular process GO:0050905 2 0.042
positive regulation of cell communication GO:0010647 271 0.041
response to molecule of bacterial origin GO:0002237 194 0.041
monovalent inorganic cation transport GO:0015672 172 0.041
vasculature development GO:0001944 70 0.041
cellular cation homeostasis GO:0030003 180 0.040
ribonucleotide metabolic process GO:0009259 231 0.040
purine ribonucleotide biosynthetic process GO:0009152 81 0.039
purine nucleotide metabolic process GO:0006163 229 0.038
regulation of nucleotide metabolic process GO:0006140 117 0.037
homeostatic process GO:0042592 331 0.037
muscle contraction GO:0006936 88 0.037
nucleoside phosphate biosynthetic process GO:1901293 102 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
head development GO:0060322 247 0.036
positive regulation of cell proliferation GO:0008284 249 0.035
cyclic nucleotide metabolic process GO:0009187 80 0.035
sexual reproduction GO:0019953 148 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
regulation of sodium ion transport GO:0002028 21 0.033
signal transduction by phosphorylation GO:0023014 144 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
small gtpase mediated signal transduction GO:0007264 36 0.032
cellular ion homeostasis GO:0006873 184 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
cellular lipid metabolic process GO:0044255 208 0.032
regulation of apoptotic process GO:0042981 335 0.032
regulation of cellular component organization GO:0051128 368 0.031
neurological system process GO:0050877 219 0.031
signal release GO:0023061 145 0.031
mapk cascade GO:0000165 140 0.031
regulation of muscle contraction GO:0006937 53 0.030
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.030
neuron neuron synaptic transmission GO:0007270 60 0.029
reproduction GO:0000003 245 0.029
regulation of catalytic activity GO:0050790 304 0.029
synaptic growth at neuromuscular junction GO:0051124 1 0.029
cellular homeostasis GO:0019725 252 0.028
sodium ion transmembrane transport GO:0035725 67 0.027
gland development GO:0048732 155 0.027
multicellular organism growth GO:0035264 1 0.026
regulation of programmed cell death GO:0043067 341 0.026
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.026
biological adhesion GO:0022610 110 0.026
gamete generation GO:0007276 124 0.026
growth GO:0040007 165 0.026
cell adhesion GO:0007155 110 0.026
ribonucleotide biosynthetic process GO:0009260 85 0.026
regulation of growth GO:0040008 105 0.026
neuron development GO:0048666 286 0.025
glutamate receptor signaling pathway GO:0007215 43 0.025
calcium ion homeostasis GO:0055074 162 0.025
regulation of signal transduction GO:0009966 318 0.025
blood circulation GO:0008015 183 0.025
developmental growth GO:0048589 100 0.025
heart contraction GO:0060047 57 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
regulation of hydrolase activity GO:0051336 143 0.024
ribose phosphate biosynthetic process GO:0046390 87 0.024
multicellular organism reproduction GO:0032504 233 0.024
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.024
cyclic purine nucleotide metabolic process GO:0052652 62 0.024
regulation of intracellular signal transduction GO:1902531 218 0.023
membrane depolarization GO:0051899 32 0.023
regulation of camp metabolic process GO:0030814 43 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
synaptic transmission glutamatergic GO:0035249 33 0.023
regulation of metal ion transport GO:0010959 118 0.023
positive regulation of secretion GO:0051047 140 0.023
synapse assembly GO:0007416 29 0.022
tissue development GO:0009888 252 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of mapk cascade GO:0043408 116 0.022
response to peptide hormone GO:0043434 278 0.022
organic substance catabolic process GO:1901575 316 0.022
positive regulation of cell death GO:0010942 184 0.022
protein localization GO:0008104 191 0.022
regulation of protein metabolic process GO:0051246 289 0.021
multi organism reproductive process GO:0044703 262 0.021
regulation of camp biosynthetic process GO:0030817 38 0.021
response to ammonium ion GO:0060359 71 0.021
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.021
response to cytokine GO:0034097 215 0.021
actin filament based process GO:0030029 86 0.021
regulation of muscle system process GO:0090257 79 0.021
blood vessel development GO:0001568 69 0.020
positive regulation of fat cell proliferation GO:0070346 1 0.020
organelle organization GO:0006996 266 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
positive regulation of synaptic transmission GO:0050806 62 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
muscle system process GO:0003012 115 0.019
regulation of cell development GO:0060284 263 0.019
ras protein signal transduction GO:0007265 29 0.019
positive regulation of signal transduction GO:0009967 175 0.019
coronary vasculature morphogenesis GO:0060977 3 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
response to peptide GO:1901652 292 0.019
regulation of phosphorylation GO:0042325 248 0.019
potassium ion transport GO:0006813 97 0.019
regulation of brown fat cell proliferation GO:0070347 1 0.019
regulation of secretion by cell GO:1903530 208 0.018
brain development GO:0007420 247 0.018
purine nucleotide biosynthetic process GO:0006164 83 0.018
regulation of heart contraction GO:0008016 48 0.018
purine containing compound catabolic process GO:0072523 138 0.018
response to lipopolysaccharide GO:0032496 191 0.018
proteolysis GO:0006508 175 0.018
establishment of protein localization GO:0045184 141 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
cellular macromolecule localization GO:0070727 122 0.018
response to histamine GO:0034776 3 0.018
response to estrogen GO:0043627 232 0.018
regulation of fat cell proliferation GO:0070344 1 0.017
response to ketone GO:1901654 182 0.017
regulation of potassium ion transport GO:0043266 29 0.017
cellular amine metabolic process GO:0044106 38 0.017
single organism reproductive process GO:0044702 297 0.017
single organism membrane organization GO:0044802 74 0.017
nucleoside metabolic process GO:0009116 179 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
catabolic process GO:0009056 351 0.017
glycerolipid metabolic process GO:0046486 67 0.017
positive regulation of heart contraction GO:0045823 15 0.016
action potential GO:0001508 54 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.016
phosphatidylcholine biosynthetic process GO:0006656 5 0.016
feeding behavior GO:0007631 53 0.016
regulation of anion transport GO:0044070 43 0.016
cellular protein localization GO:0034613 122 0.016
camp biosynthetic process GO:0006171 47 0.016
positive regulation of molecular function GO:0044093 230 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
circulatory system process GO:0003013 183 0.016
regulation of homeostatic process GO:0032844 101 0.016
response to wounding GO:0009611 254 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
developmental induction GO:0031128 2 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
response to alkaloid GO:0043279 132 0.016
angiogenesis GO:0001525 53 0.015
spermatogenesis GO:0007283 99 0.015
hormone transport GO:0009914 121 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
neuron differentiation GO:0030182 368 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regulation of nucleotide biosynthetic process GO:0030808 47 0.015
regulation of lyase activity GO:0051339 22 0.015
oxoacid metabolic process GO:0043436 290 0.015
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.015
negative regulation of cell communication GO:0010648 158 0.015
nucleotide catabolic process GO:0009166 139 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.015
divalent metal ion transport GO:0070838 132 0.015
amine metabolic process GO:0009308 38 0.014
programmed cell death GO:0012501 392 0.014
positive regulation of cardiac muscle tissue growth GO:0055023 9 0.014
positive regulation of synaptic vesicle transport GO:1902805 3 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
neurotransmitter secretion GO:0007269 33 0.014
lipid metabolic process GO:0006629 283 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
defecation GO:0030421 1 0.014
neuron projection development GO:0031175 273 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
male gamete generation GO:0048232 99 0.014
regulation of organ formation GO:0003156 2 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.014
negative regulation of long term synaptic potentiation GO:1900272 1 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
protein oligomerization GO:0051259 191 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
reproductive system development GO:0061458 128 0.013
rna biosynthetic process GO:0032774 380 0.013
muscle structure development GO:0061061 87 0.013
positive regulation of voltage gated calcium channel activity GO:1901387 1 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
phospholipid biosynthetic process GO:0008654 29 0.013
axis specification GO:0009798 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of blood circulation GO:1903522 110 0.013
response to oxygen levels GO:0070482 265 0.013
response to toxic substance GO:0009636 133 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
response to bacterium GO:0009617 200 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
response to hypoxia GO:0001666 231 0.013
cardiovascular system development GO:0072358 134 0.013
response to external biotic stimulus GO:0043207 221 0.013
cell migration GO:0016477 197 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
regulation of body fluid levels GO:0050878 90 0.012
small molecule biosynthetic process GO:0044283 124 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of calcium ion transport GO:0051924 77 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
forebrain development GO:0030900 98 0.012
positive regulation of cell development GO:0010720 176 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
negative regulation of metabolic process GO:0009892 331 0.012
striated muscle contraction GO:0006941 44 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
n methyl d aspartate receptor clustering GO:0097114 2 0.012
aging GO:0007568 241 0.012
neuronal action potential GO:0019228 35 0.012
regulation of striated muscle contraction GO:0006942 21 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
calcium ion transport GO:0006816 131 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
organ induction GO:0001759 1 0.011
sex differentiation GO:0007548 113 0.011
regulation of developmental growth GO:0048638 45 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of saliva secretion GO:0046877 3 0.011
cellular response to metal ion GO:0071248 55 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
regulation of secretion GO:0051046 224 0.011
cellular catabolic process GO:0044248 295 0.011
protein homooligomerization GO:0051260 91 0.011
nitrogen compound transport GO:0071705 229 0.011
synaptic transmission GO:0007268 235 0.011
regulation of neuron differentiation GO:0045664 208 0.011
muscle organ development GO:0007517 50 0.011
regulation of system process GO:0044057 208 0.011
multicellular organismal signaling GO:0035637 44 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
regulation of nervous system development GO:0051960 264 0.011
regulation of cell projection organization GO:0031344 175 0.011
potassium ion transmembrane transport GO:0071805 71 0.011
positive regulation of protein modification process GO:0031401 142 0.011
single organism catabolic process GO:0044712 283 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
positive regulation of ion transport GO:0043270 94 0.011
regulation of cardiac muscle tissue growth GO:0055021 12 0.011
neuronal ion channel clustering GO:0045161 3 0.010
synapse organization GO:0050808 46 0.010
negative regulation of nucleotide metabolic process GO:0045980 23 0.010
heterocycle catabolic process GO:0046700 167 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
sequestering of metal ion GO:0051238 9 0.010
regulation of heart growth GO:0060420 12 0.010
developmental process involved in reproduction GO:0003006 159 0.010
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cellular chemical homeostasis GO:0055082 247 0.010

Ica1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011