Rattus norvegicus

40 known processes

Icos

inducible T-cell co-stimulator

(Aliases: Ailim)

Icos biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of locomotion GO:0040012 148 0.267
positive regulation of cellular component movement GO:0051272 102 0.233
cell motility GO:0048870 202 0.221
cellular component movement GO:0006928 248 0.189
cellular amino acid metabolic process GO:0006520 107 0.187
response to acid chemical GO:0001101 222 0.185
immune system process GO:0002376 204 0.184
regulation of cell proliferation GO:0042127 359 0.181
neuron apoptotic process GO:0051402 88 0.177
regulation of cellular component movement GO:0051270 150 0.161
apoptotic process GO:0006915 381 0.158
rna biosynthetic process GO:0032774 380 0.151
positive regulation of cell motility GO:2000147 97 0.150
response to monosaccharide GO:0034284 159 0.149
cellular response to lipid GO:0071396 201 0.137
cellular response to stress GO:0033554 269 0.135
cell adhesion GO:0007155 110 0.133
tissue development GO:0009888 252 0.117
transcription dna templated GO:0006351 377 0.116
response to hypoxia GO:0001666 231 0.113
regulation of cell motility GO:2000145 131 0.113
cell activation GO:0001775 97 0.111
localization of cell GO:0051674 202 0.108
response to toxic substance GO:0009636 133 0.105
regulation of nucleic acid templated transcription GO:1903506 380 0.104
macromolecule localization GO:0033036 252 0.103
neuron death GO:0070997 127 0.102
response to inorganic substance GO:0010035 377 0.101
response to oxygen levels GO:0070482 265 0.099
multicellular organism reproduction GO:0032504 233 0.097
programmed cell death GO:0012501 392 0.096
regulation of protein metabolic process GO:0051246 289 0.093
antigen receptor mediated signaling pathway GO:0050851 1 0.092
response to metal ion GO:0010038 253 0.091
response to carbohydrate GO:0009743 183 0.090
response to nutrient levels GO:0031667 370 0.090
positive regulation of multicellular organismal process GO:0051240 387 0.089
positive regulation of cell proliferation GO:0008284 249 0.088
regulation of cellular protein metabolic process GO:0032268 267 0.087
reproductive process GO:0022414 372 0.087
regulation of molecular function GO:0065009 398 0.085
positive regulation of molecular function GO:0044093 230 0.083
oxoacid metabolic process GO:0043436 290 0.083
cell migration GO:0016477 197 0.081
cellular response to oxygen containing compound GO:1901701 386 0.081
sex differentiation GO:0007548 113 0.080
negative regulation of gene expression GO:0010629 199 0.079
regulation of rna biosynthetic process GO:2001141 381 0.079
blood circulation GO:0008015 183 0.079
cellular ketone metabolic process GO:0042180 51 0.079
leukocyte activation GO:0045321 76 0.078
neuron projection development GO:0031175 273 0.078
anatomical structure morphogenesis GO:0009653 298 0.077
locomotion GO:0040011 237 0.074
regulation of programmed cell death GO:0043067 341 0.074
formation of primary germ layer GO:0001704 1 0.072
protein maturation GO:0051604 68 0.071
negative regulation of cell death GO:0060548 229 0.071
development of primary sexual characteristics GO:0045137 107 0.071
regulation of system process GO:0044057 208 0.070
response to extracellular stimulus GO:0009991 380 0.068
proteolysis GO:0006508 175 0.068
rna metabolic process GO:0016070 406 0.068
regulation of phosphorylation GO:0042325 248 0.068
positive regulation of cellular biosynthetic process GO:0031328 295 0.067
response to corticosteroid GO:0031960 235 0.066
negative regulation of programmed cell death GO:0043069 183 0.066
single organism catabolic process GO:0044712 283 0.065
regulation of transcription dna templated GO:0006355 374 0.064
regulation of signal transduction GO:0009966 318 0.064
appendage morphogenesis GO:0035107 4 0.063
vesicle mediated transport GO:0016192 181 0.063
regulation of protein modification process GO:0031399 194 0.063
response to growth factor GO:0070848 189 0.062
positive regulation of leukocyte activation GO:0002696 30 0.062
positive regulation of protein metabolic process GO:0051247 178 0.062
nucleic acid templated transcription GO:0097659 379 0.061
organic acid metabolic process GO:0006082 292 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
positive regulation of hydrolase activity GO:0051345 86 0.060
positive regulation of phosphate metabolic process GO:0045937 262 0.060
negative regulation of metabolic process GO:0009892 331 0.058
transcription from rna polymerase ii promoter GO:0006366 252 0.058
cytokine mediated signaling pathway GO:0019221 43 0.057
response to bacterium GO:0009617 200 0.056
regulation of neuron death GO:1901214 115 0.056
positive regulation of nervous system development GO:0051962 178 0.056
regulation of apoptotic process GO:0042981 335 0.055
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.055
regulation of phosphate metabolic process GO:0019220 349 0.054
reproduction GO:0000003 245 0.054
cell morphogenesis involved in differentiation GO:0000904 119 0.054
cellular response to extracellular stimulus GO:0031668 73 0.053
regulation of blood circulation GO:1903522 110 0.053
negative regulation of cellular biosynthetic process GO:0031327 161 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
positive regulation of transcription dna templated GO:0045893 197 0.052
cellular response to hormone stimulus GO:0032870 247 0.051
positive regulation of catalytic activity GO:0043085 184 0.051
multi organism reproductive process GO:0044703 262 0.051
regulation of catalytic activity GO:0050790 304 0.051
sexual reproduction GO:0019953 148 0.050
biological adhesion GO:0022610 110 0.050
positive regulation of rna biosynthetic process GO:1902680 197 0.050
regulation of hydrolase activity GO:0051336 143 0.050
regulation of cellular amino acid metabolic process GO:0006521 2 0.049
catabolic process GO:0009056 351 0.049
positive regulation of cell activation GO:0050867 34 0.049
regulation of cellular localization GO:0060341 263 0.049
gonad development GO:0008406 104 0.049
cellular response to biotic stimulus GO:0071216 59 0.048
intracellular signal transduction GO:0035556 314 0.048
t cell activation GO:0042110 29 0.048
muscle contraction GO:0006936 88 0.047
protein phosphorylation GO:0006468 345 0.047
regulation of neuron apoptotic process GO:0043523 83 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
positive regulation of immune system process GO:0002684 90 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
negative regulation of apoptotic process GO:0043066 181 0.045
chemotaxis GO:0006935 66 0.045
circulatory system process GO:0003013 183 0.045
response to nutrient GO:0007584 248 0.045
cell growth GO:0016049 104 0.044
negative regulation of multicellular organismal process GO:0051241 203 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.044
regulation of anatomical structure morphogenesis GO:0022603 141 0.044
regulation of cell migration GO:0030334 128 0.044
cell projection organization GO:0030030 302 0.043
epithelium development GO:0060429 96 0.043
positive regulation of response to stimulus GO:0048584 285 0.043
cell type specific apoptotic process GO:0097285 134 0.042
regulation of secretion by cell GO:1903530 208 0.042
positive regulation of biosynthetic process GO:0009891 319 0.041
regulation of rna metabolic process GO:0051252 391 0.040
regulation of leukocyte activation GO:0002694 45 0.040
single organism reproductive process GO:0044702 297 0.040
positive regulation of locomotion GO:0040017 102 0.040
muscle system process GO:0003012 115 0.040
wound healing GO:0042060 122 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
positive regulation of gene expression GO:0010628 244 0.039
defense response GO:0006952 194 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
cellular catabolic process GO:0044248 295 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.037
chemical homeostasis GO:0048878 292 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
positive regulation of programmed cell death GO:0043068 157 0.036
cellular response to growth factor stimulus GO:0071363 162 0.036
cellular response to endogenous stimulus GO:0071495 377 0.036
response to oxidative stress GO:0006979 186 0.036
response to vitamin GO:0033273 131 0.035
reproductive structure development GO:0048608 128 0.035
mononuclear cell proliferation GO:0032943 29 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
organic substance catabolic process GO:1901575 316 0.035
regulation of cellular component organization GO:0051128 368 0.035
regulation of cell projection organization GO:0031344 175 0.035
cell activation involved in immune response GO:0002263 16 0.034
negative regulation of transcription dna templated GO:0045892 116 0.034
response to glucocorticoid GO:0051384 223 0.034
cellular chemical homeostasis GO:0055082 247 0.033
cellular response to molecule of bacterial origin GO:0071219 56 0.033
single organism carbohydrate metabolic process GO:0044723 118 0.033
response to hydrogen peroxide GO:0042542 89 0.033
response to cytokine GO:0034097 215 0.033
single organismal cell cell adhesion GO:0016337 42 0.032
cellular response to peptide GO:1901653 133 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
regulation of immune system process GO:0002682 123 0.032
neuron differentiation GO:0030182 368 0.032
cellular carbohydrate metabolic process GO:0044262 72 0.032
carbohydrate metabolic process GO:0005975 130 0.031
positive regulation of transport GO:0051050 245 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
regulation of protein kinase activity GO:0045859 105 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
regulation of transferase activity GO:0051338 123 0.031
cellular amine metabolic process GO:0044106 38 0.031
urogenital system development GO:0001655 78 0.031
positive regulation of cell projection organization GO:0031346 111 0.031
t cell receptor signaling pathway GO:0050852 1 0.030
gastrulation GO:0007369 2 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
growth GO:0040007 165 0.030
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
aging GO:0007568 241 0.030
positive regulation of lymphocyte activation GO:0051251 25 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
hindlimb morphogenesis GO:0035137 2 0.029
secretion by cell GO:0032940 248 0.029
leukocyte proliferation GO:0070661 29 0.029
cellular response to external stimulus GO:0071496 118 0.029
leukocyte activation involved in immune response GO:0002366 16 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
developmental process involved in reproduction GO:0003006 159 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.027
protein processing GO:0016485 68 0.027
neuromuscular process GO:0050905 2 0.027
immune response GO:0006955 104 0.027
gamete generation GO:0007276 124 0.027
membrane organization GO:0061024 94 0.027
regulation of cell differentiation GO:0045595 320 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
response to estrogen GO:0043627 232 0.026
neuron development GO:0048666 286 0.026
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
regulation of cell growth GO:0001558 85 0.026
lymphocyte activation GO:0046649 43 0.026
positive regulation of developmental process GO:0051094 283 0.026
cell morphogenesis GO:0000902 142 0.026
positive regulation of cell death GO:0010942 184 0.026
positive regulation of mapk cascade GO:0043410 92 0.026
response to heat GO:0009408 60 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
cell cycle GO:0007049 101 0.026
cell part morphogenesis GO:0032990 123 0.026
regulation of cell development GO:0060284 263 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.025
positive regulation of protein modification process GO:0031401 142 0.025
positive regulation of cell migration GO:0030335 96 0.025
protein complex assembly GO:0006461 263 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
developmental growth GO:0048589 100 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
regulation of mapk cascade GO:0043408 116 0.025
leukocyte migration GO:0050900 38 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
sequestering of metal ion GO:0051238 9 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
oxidation reduction process GO:0055114 304 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
activation of protein kinase b activity GO:0032148 3 0.024
protein complex subunit organization GO:0071822 302 0.024
brain development GO:0007420 247 0.024
negative regulation of protein metabolic process GO:0051248 114 0.024
response to ketone GO:1901654 182 0.024
regulation of hormone levels GO:0010817 187 0.023
cytokine biosynthetic process GO:0042089 3 0.023
amine metabolic process GO:0009308 38 0.023
cytokine production GO:0001816 61 0.023
regulation of secretion GO:0051046 224 0.023
embryonic limb morphogenesis GO:0030326 4 0.023
positive regulation of cell adhesion GO:0045785 30 0.023
neurological system process GO:0050877 219 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
positive regulation of cell development GO:0010720 176 0.023
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.023
regulation of protein processing GO:0070613 50 0.023
angioblast cell migration GO:0035476 1 0.023
homeostatic process GO:0042592 331 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
b cell activation involved in immune response GO:0002312 1 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
response to decreased oxygen levels GO:0036293 237 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
regulation of nervous system development GO:0051960 264 0.022
ion homeostasis GO:0050801 212 0.022
mapk cascade GO:0000165 140 0.022
regulation of dna metabolic process GO:0051052 60 0.022
coagulation GO:0050817 28 0.021
response to insulin GO:0032868 133 0.021
protein autophosphorylation GO:0046777 66 0.021
cellular response to nutrient levels GO:0031669 60 0.021
regulation of phagocytosis engulfment GO:0060099 4 0.021
positive regulation of immune response GO:0050778 42 0.020
peptidyl tyrosine phosphorylation GO:0018108 72 0.020
regulation of anatomical structure size GO:0090066 135 0.020
regulation of vasculature development GO:1901342 44 0.020
regulation of neurogenesis GO:0050767 247 0.020
response to peptide GO:1901652 292 0.020
muscle cell migration GO:0014812 36 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
spermatogenesis GO:0007283 99 0.020
cellular component biogenesis GO:0044085 368 0.020
platelet aggregation GO:0070527 4 0.020
sequestering of calcium ion GO:0051208 8 0.020
cardiovascular system development GO:0072358 134 0.020
negative regulation of long term synaptic potentiation GO:1900272 1 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
epithelial cell differentiation GO:0030855 71 0.019
gland development GO:0048732 155 0.019
regulation of blood vessel endothelial cell migration GO:0043535 4 0.019
response to biotic stimulus GO:0009607 226 0.019
cellular cation homeostasis GO:0030003 180 0.019
central nervous system development GO:0007417 311 0.019
regulation of t cell activation GO:0050863 23 0.019
response to external biotic stimulus GO:0043207 221 0.019
regulation of growth GO:0040008 105 0.019
regulation of muscle contraction GO:0006937 53 0.019
purine containing compound metabolic process GO:0072521 253 0.019
regulation of ion transport GO:0043269 245 0.019
immune system development GO:0002520 41 0.019
hemopoiesis GO:0030097 34 0.018
blood vessel morphogenesis GO:0048514 58 0.018
positive regulation of map kinase activity GO:0043406 46 0.018
reproductive system development GO:0061458 128 0.018
regulation of immunoglobulin secretion GO:0051023 1 0.018
tube development GO:0035295 89 0.018
positive regulation of lymphocyte proliferation GO:0050671 20 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
cellular homeostasis GO:0019725 252 0.017
somatic stem cell division GO:0048103 2 0.017
positive regulation of kinase activity GO:0033674 77 0.017
response to mechanical stimulus GO:0009612 134 0.017
positive regulation of leukocyte proliferation GO:0070665 20 0.017
regulation of transmembrane transporter activity GO:0022898 49 0.017
neuron projection morphogenesis GO:0048812 122 0.017
organ formation GO:0048645 3 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
response to alkaloid GO:0043279 132 0.017
regulation of smooth muscle cell migration GO:0014910 36 0.017
ras protein signal transduction GO:0007265 29 0.017
embryonic appendage morphogenesis GO:0035113 4 0.017
positive regulation of cell growth GO:0030307 44 0.017
regulation of endopeptidase activity GO:0052548 51 0.017
regulation of cell morphogenesis GO:0022604 77 0.017
negative regulation of rna splicing GO:0033119 3 0.017
cellular ion homeostasis GO:0006873 184 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
protein complex biogenesis GO:0070271 263 0.017
negative regulation of signaling GO:0023057 157 0.016
response to purine containing compound GO:0014074 126 0.016
cell cycle process GO:0022402 57 0.016
regulation of kinase activity GO:0043549 117 0.016
peptidyl amino acid modification GO:0018193 126 0.016
response to hexose GO:0009746 144 0.016
regulation of behavior GO:0050795 61 0.016
dephosphorylation GO:0016311 98 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of protein transport GO:0051223 68 0.016
response to increased oxygen levels GO:0036296 45 0.016
mast cell activation GO:0045576 15 0.016
regulation of cell activation GO:0050865 50 0.016
cell projection morphogenesis GO:0048858 123 0.016
single organism cell adhesion GO:0098602 46 0.016
response to osmotic stress GO:0006970 42 0.016
positive regulation of neuron apoptotic process GO:0043525 33 0.016
cerebral cortex tangential migration GO:0021800 1 0.015
telencephalon development GO:0021537 62 0.015
immune effector process GO:0002252 53 0.015
cellular response to ketone GO:1901655 51 0.015
b cell differentiation GO:0030183 2 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cellular response to vitamin GO:0071295 21 0.015
single organism membrane organization GO:0044802 74 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
taxis GO:0042330 67 0.015
regulation of transmembrane transport GO:0034762 122 0.015
regulation of neuron differentiation GO:0045664 208 0.015
energy derivation by oxidation of organic compounds GO:0015980 46 0.015
intracellular transport GO:0046907 185 0.015
positive regulation of cell communication GO:0010647 271 0.015
single organism biosynthetic process GO:0044711 342 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.015
axonogenesis GO:0007409 71 0.015
regulation of vasoconstriction GO:0019229 44 0.015
salivary gland morphogenesis GO:0007435 1 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
regulation of cell adhesion GO:0030155 52 0.015
negative regulation of homeostatic process GO:0032845 47 0.015
positive regulation of neuron projection development GO:0010976 99 0.014
regulation of immune response GO:0050776 55 0.014
vasculature development GO:0001944 70 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
myeloid leukocyte activation GO:0002274 36 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
organelle organization GO:0006996 266 0.014
leukocyte differentiation GO:0002521 30 0.014
embryonic hindlimb morphogenesis GO:0035116 2 0.014
neutrophil apoptotic process GO:0001781 4 0.014
response to tumor necrosis factor GO:0034612 56 0.014
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.014
histamine production involved in inflammatory response GO:0002349 3 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
sensory perception GO:0007600 101 0.014
tissue remodeling GO:0048771 40 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
regulation of homotypic cell cell adhesion GO:0034110 4 0.014
activation of phospholipase d activity GO:0031584 2 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
exocytosis GO:0006887 60 0.014
positive regulation of positive chemotaxis GO:0050927 7 0.014
regulation of neutrophil migration GO:1902622 6 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.013
clustering of voltage gated potassium channels GO:0045163 1 0.013
regulation of map kinase activity GO:0043405 53 0.013
regulation of cell cycle GO:0051726 73 0.013
substrate dependent cell migration GO:0006929 1 0.013
cellular response to lipopolysaccharide GO:0071222 55 0.013
adaptive immune response GO:0002250 14 0.013
response to hyperoxia GO:0055093 45 0.013
response to antibiotic GO:0046677 39 0.013
response to glucose GO:0009749 136 0.013
regulation of smooth muscle contraction GO:0006940 29 0.013
regulation of cytokine biosynthetic process GO:0042035 3 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
protein localization GO:0008104 191 0.013
regulation of axonogenesis GO:0050770 37 0.013
regulation of carbohydrate metabolic process GO:0006109 41 0.013
cation homeostasis GO:0055080 195 0.013
myeloid cell activation involved in immune response GO:0002275 13 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
axis specification GO:0009798 4 0.013
salivary gland development GO:0007431 3 0.013
response to activity GO:0014823 73 0.013
regulation of mononuclear cell proliferation GO:0032944 26 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
response to vitamin d GO:0033280 34 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
sensory perception of bitter taste GO:0050913 4 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of peptidase activity GO:0052547 55 0.012
stem cell division GO:0017145 4 0.012
response to wounding GO:0009611 254 0.012
epithelial cell migration GO:0010631 19 0.012
protein oligomerization GO:0051259 191 0.012
renal system development GO:0072001 67 0.012
cell fate determination GO:0001709 2 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to peptide hormone GO:0043434 278 0.012
cellular component assembly GO:0022607 360 0.012
cellular protein localization GO:0034613 122 0.012
blood vessel development GO:0001568 69 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
regulation of axon extension GO:0030516 24 0.012
positive regulation of signal transduction GO:0009967 175 0.012
mitotic spindle organization GO:0007052 2 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
lymphocyte activation involved in immune response GO:0002285 3 0.012
positive regulation of alpha beta t cell activation GO:0046635 2 0.012
prostate gland morphogenesis GO:0060512 2 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
organophosphate metabolic process GO:0019637 370 0.012
olfactory bulb interneuron differentiation GO:0021889 1 0.011
neuron projection extension GO:1990138 26 0.011
response to other organism GO:0051707 220 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
regulation of exocytosis GO:0017157 37 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.011
limb morphogenesis GO:0035108 4 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
macromolecular complex assembly GO:0065003 273 0.011
male gamete generation GO:0048232 99 0.011
lipid metabolic process GO:0006629 283 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
negative regulation of developmental process GO:0051093 125 0.011
cell cell signaling GO:0007267 335 0.011
calcium ion homeostasis GO:0055074 162 0.011
secretion GO:0046903 307 0.011
regulation of protein maturation GO:1903317 50 0.011
divalent inorganic cation transport GO:0072511 134 0.011
male sex differentiation GO:0046661 64 0.011
response to retinoic acid GO:0032526 63 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of transferase activity GO:0051347 81 0.011
positive regulation of smooth muscle cell migration GO:0014911 27 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
metanephric tubule morphogenesis GO:0072173 2 0.011
hormone metabolic process GO:0042445 69 0.011
positive regulation of secretion GO:0051047 140 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.011
leukocyte mediated immunity GO:0002443 28 0.011
regulation of proteolysis GO:0030162 66 0.011
kidney development GO:0001822 67 0.010
negative regulation of signal transduction GO:0009968 83 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.010
regulation of leukocyte proliferation GO:0070663 26 0.010
regulation of cell cell adhesion GO:0022407 14 0.010
negative regulation of bone resorption GO:0045779 5 0.010
response to estradiol GO:0032355 164 0.010
bmp signaling pathway GO:0030509 4 0.010
regulation of lymphocyte proliferation GO:0050670 26 0.010
negative regulation of osteoblast differentiation GO:0045668 2 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
regulation of extent of cell growth GO:0061387 25 0.010

Icos disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
musculoskeletal system disease DOID:17 0 0.057
connective tissue disease DOID:65 0 0.057