Rattus norvegicus

0 known processes

Ifit3

interferon-induced protein with tetratricopeptide repeats 3

(Aliases: MGC94037)

Ifit3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.900
Human
response to virus GO:0009615 17 0.825
Human
negative regulation of viral genome replication GO:0045071 1 0.787
cellular response to interleukin 1 GO:0071347 37 0.748
immune response GO:0006955 104 0.640
response to cytokine GO:0034097 215 0.445
Mouse
myeloid leukocyte migration GO:0097529 20 0.420
positive regulation of t cell migration GO:2000406 1 0.360
response to external biotic stimulus GO:0043207 221 0.336
Human
response to other organism GO:0051707 220 0.335
Human
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.220
regulation of jak stat cascade GO:0046425 21 0.188
reproductive process GO:0022414 372 0.178
negative regulation of viral process GO:0048525 4 0.167
viral genome replication GO:0019079 2 0.166
negative regulation of cellular metabolic process GO:0031324 281 0.154
innate immune response GO:0045087 35 0.153
response to dsrna GO:0043331 9 0.128
cellular response to oxygen containing compound GO:1901701 386 0.126
immune system process GO:0002376 204 0.126
t cell chemotaxis GO:0010818 2 0.119
defense response GO:0006952 194 0.115
response to exogenous dsrna GO:0043330 3 0.110
positive regulation of jak stat cascade GO:0046427 19 0.106
positive regulation of multicellular organismal process GO:0051240 387 0.098
regulation of t cell migration GO:2000404 1 0.092
acute inflammatory response GO:0002526 58 0.091
jak stat cascade GO:0007259 26 0.089
response to extracellular stimulus GO:0009991 380 0.087
nucleotide metabolic process GO:0009117 279 0.083
defense response to other organism GO:0098542 17 0.082
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.081
homeostatic process GO:0042592 331 0.080
response to estrogen GO:0043627 232 0.080
cellular response to lipid GO:0071396 201 0.072
response to nutrient levels GO:0031667 370 0.072
regulation of viral genome replication GO:0045069 2 0.070
cellular response to biotic stimulus GO:0071216 59 0.067
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.066
response to nutrient GO:0007584 248 0.063
response to interleukin 1 GO:0070555 55 0.059
multi organism reproductive process GO:0044703 262 0.056
response to vitamin GO:0033273 131 0.056
metal ion transport GO:0030001 289 0.055
response to mechanical stimulus GO:0009612 134 0.052
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.051
positive regulation of lymphocyte migration GO:2000403 1 0.050
cellular response to external stimulus GO:0071496 118 0.050
lymphocyte chemotaxis GO:0048247 3 0.049
carboxylic acid metabolic process GO:0019752 289 0.049
regulation of nervous system development GO:0051960 264 0.048
response to acid chemical GO:0001101 222 0.048
positive regulation of programmed cell death GO:0043068 157 0.047
cellular response to stress GO:0033554 269 0.046
macromolecular complex assembly GO:0065003 273 0.046
positive regulation of nervous system development GO:0051962 178 0.045
regulation of rna metabolic process GO:0051252 391 0.045
regulation of immune system process GO:0002682 123 0.044
negative regulation of metabolic process GO:0009892 331 0.044
lymphocyte migration GO:0072676 3 0.043
regulation of response to external stimulus GO:0032101 106 0.043
regulation of necroptotic process GO:0060544 2 0.042
metal ion homeostasis GO:0055065 186 0.042
response to purine containing compound GO:0014074 126 0.041
positive regulation of camp mediated signaling GO:0043950 2 0.041
negative regulation of protein metabolic process GO:0051248 114 0.041
regulation of catalytic activity GO:0050790 304 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.040
cation transport GO:0006812 382 0.040
necroptotic process GO:0070266 2 0.040
regulation of protein metabolic process GO:0051246 289 0.040
response to interferon beta GO:0035456 1 0.039
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.038
cellular response to endogenous stimulus GO:0071495 377 0.038
positive regulation of potassium ion transport GO:0043268 13 0.038
positive regulation of cell migration GO:0030335 96 0.038
positive regulation of rna metabolic process GO:0051254 203 0.037
g protein coupled receptor signaling pathway GO:0007186 242 0.037
positive regulation of cell projection organization GO:0031346 111 0.037
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.037
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.036
response to amine GO:0014075 46 0.036
response to glucocorticoid GO:0051384 223 0.036
regulation of hydrolase activity GO:0051336 143 0.036
developmental process involved in reproduction GO:0003006 159 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
reproduction GO:0000003 245 0.035
protein oligomerization GO:0051259 191 0.034
positive regulation of response to external stimulus GO:0032103 51 0.034
regulation of response to stress GO:0080134 126 0.034
organophosphate metabolic process GO:0019637 370 0.033
regulation of tolerance induction to nonself antigen GO:0002655 1 0.033
amine metabolic process GO:0009308 38 0.033
regulation of cell motility GO:2000145 131 0.033
positive regulation of gene expression GO:0010628 244 0.033
response to lipopolysaccharide GO:0032496 191 0.033
transcription dna templated GO:0006351 377 0.033
cardiovascular system development GO:0072358 134 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.033
cytokine mediated signaling pathway GO:0019221 43 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.032
protein phosphorylation GO:0006468 345 0.032
ion homeostasis GO:0050801 212 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
vasculature development GO:0001944 70 0.032
oxoacid metabolic process GO:0043436 290 0.031
cytokine production GO:0001816 61 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
negative regulation of innate immune response GO:0045824 4 0.031
positive regulation of neuron projection development GO:0010976 99 0.031
regulation of programmed cell death GO:0043067 341 0.031
Human
rna metabolic process GO:0016070 406 0.031
regulation of lymphocyte migration GO:2000401 1 0.031
divalent inorganic cation transport GO:0072511 134 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of intracellular transport GO:0032388 39 0.030
negative regulation of response to stimulus GO:0048585 155 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
response to low density lipoprotein particle GO:0055098 4 0.029
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.028
response to interferon alpha GO:0035455 1 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
cellular response to molecule of bacterial origin GO:0071219 56 0.028
eosinophil chemotaxis GO:0048245 3 0.028
inflammatory response GO:0006954 150 0.027
circulatory system development GO:0072359 134 0.027
defense response to virus GO:0051607 9 0.027
regulation of cell development GO:0060284 263 0.027
regulation of neuron projection development GO:0010975 161 0.027
response to growth factor GO:0070848 189 0.027
multicellular organism reproduction GO:0032504 233 0.027
regulation of chemotaxis GO:0050920 29 0.026
protein transport GO:0015031 132 0.026
positive regulation of cell development GO:0010720 176 0.026
intracellular signal transduction GO:0035556 314 0.026
macromolecule localization GO:0033036 252 0.026
organ regeneration GO:0031100 101 0.026
aging GO:0007568 241 0.026
regulation of phosphorylation GO:0042325 248 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.025
negative regulation of protein phosphorylation GO:0001933 44 0.025
single organism reproductive process GO:0044702 297 0.025
calcium ion transport GO:0006816 131 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
sequestering of metal ion GO:0051238 9 0.024
reproductive structure development GO:0048608 128 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
regulation of camp metabolic process GO:0030814 43 0.024
response to corticosteroid GO:0031960 235 0.024
cellular response to iron iii ion GO:0071283 3 0.024
chemical homeostasis GO:0048878 292 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.023
maintenance of location GO:0051235 17 0.023
cellular response to reactive oxygen species GO:0034614 55 0.023
response to heat GO:0009408 60 0.023
localization of cell GO:0051674 202 0.023
positive regulation of chemotaxis GO:0050921 23 0.023
cellular response to nutrient levels GO:0031669 60 0.022
immune effector process GO:0002252 53 0.022
regulation of cellular component movement GO:0051270 150 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
cell migration GO:0016477 197 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
response to inorganic substance GO:0010035 377 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
positive regulation of behavior GO:0048520 38 0.021
negative regulation of cell communication GO:0010648 158 0.021
response to organophosphorus GO:0046683 102 0.021
regulation of neuron differentiation GO:0045664 208 0.021
cellular ketone metabolic process GO:0042180 51 0.021
regulation of calcium ion transport into cytosol GO:0010522 25 0.021
protein complex assembly GO:0006461 263 0.021
negative regulation of blood vessel morphogenesis GO:2000181 10 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
cellular amine metabolic process GO:0044106 38 0.020
maternal process involved in female pregnancy GO:0060135 38 0.020
regulation of molecular function GO:0065009 398 0.020
response to monosaccharide GO:0034284 159 0.020
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.020
sodium ion transport GO:0006814 82 0.020
response to bacterium GO:0009617 200 0.020
negative regulation of vasculature development GO:1901343 11 0.020
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.020
regeneration GO:0031099 163 0.019
negative regulation of gene expression GO:0010629 199 0.019
granulocyte migration GO:0097530 16 0.019
regulation of serine type peptidase activity GO:1902571 1 0.019
negative regulation of molecular function GO:0044092 133 0.019
response to wounding GO:0009611 254 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
proteolysis GO:0006508 175 0.019
positive regulation of cytokine production GO:0001819 42 0.019
t cell migration GO:0072678 2 0.019
stress activated protein kinase signaling cascade GO:0031098 37 0.019
cellular chemical homeostasis GO:0055082 247 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
response to tumor necrosis factor GO:0034612 56 0.018
positive regulation of cytoplasmic transport GO:1903651 32 0.018
neurological system process GO:0050877 219 0.018
t helper 1 cell diapedesis GO:0035688 1 0.018
tolerance induction dependent upon immune response GO:0002461 2 0.018
regulation of potassium ion transport GO:0043266 29 0.018
cellular ion homeostasis GO:0006873 184 0.018
glucose homeostasis GO:0042593 75 0.018
tolerance induction to nonself antigen GO:0002462 2 0.018
positive regulation of necrotic cell death GO:0010940 4 0.018
cellular component assembly GO:0022607 360 0.018
regulation of cytokine biosynthetic process GO:0042035 3 0.018
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 2 0.017
heterotypic cell cell adhesion GO:0034113 2 0.017
regulation of cell migration GO:0030334 128 0.017
neuron projection development GO:0031175 273 0.017
potassium ion transport GO:0006813 97 0.017
response to starvation GO:0042594 59 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
response to vitamin d GO:0033280 34 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
reactive nitrogen species metabolic process GO:2001057 1 0.016
regulation of calcium ion transport GO:0051924 77 0.016
programmed necrotic cell death GO:0097300 2 0.016
neuron differentiation GO:0030182 368 0.016
regulation of neurogenesis GO:0050767 247 0.016
protein homooligomerization GO:0051260 91 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
response to retinoic acid GO:0032526 63 0.016
intracellular transport GO:0046907 185 0.016
positive regulation of cell death GO:0010942 184 0.016
cellular lipid metabolic process GO:0044255 208 0.016
regulation of cell differentiation GO:0045595 320 0.016
female pregnancy GO:0007565 122 0.016
response to amphetamine GO:0001975 25 0.016
cellular homeostasis GO:0019725 252 0.016
cell chemotaxis GO:0060326 31 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
locomotion GO:0040011 237 0.016
renal system development GO:0072001 67 0.015
secretion GO:0046903 307 0.015
myeloid leukocyte activation GO:0002274 36 0.015
protein localization GO:0008104 191 0.015
negative regulation of response to tumor cell GO:0002835 2 0.015
organic acid metabolic process GO:0006082 292 0.015
cellular response to lipopolysaccharide GO:0071222 55 0.015
negative regulation of developmental process GO:0051093 125 0.015
sexual reproduction GO:0019953 148 0.015
endothelial cell proliferation GO:0001935 20 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of cell proliferation GO:0042127 359 0.015
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
central nervous system development GO:0007417 311 0.015
cellular response to metal ion GO:0071248 55 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
negative regulation of signaling GO:0023057 157 0.014
peptide transport GO:0015833 97 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
negative regulation of proteolysis GO:0045861 41 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
blood circulation GO:0008015 183 0.014
cellular response to tumor necrosis factor GO:0071356 46 0.014
epithelium development GO:0060429 96 0.014
release of sequestered calcium ion into cytosol GO:0051209 25 0.014
viral transcription GO:0019083 2 0.014
cellular cation homeostasis GO:0030003 180 0.014
negative regulation of jak stat cascade GO:0046426 3 0.014
response to oxygen levels GO:0070482 265 0.014
protein maturation GO:0051604 68 0.014
regulation of monocyte chemotaxis GO:0090025 3 0.014
cell motility GO:0048870 202 0.014
response to alkyl hydroperoxide GO:0033195 1 0.014
negative regulation of homeostatic process GO:0032845 47 0.014
regulation of vasculature development GO:1901342 44 0.014
positive regulation of humoral immune response GO:0002922 2 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of apoptotic process GO:0042981 335 0.013
Human
regulation of protein modification process GO:0031399 194 0.013
rna biosynthetic process GO:0032774 380 0.013
apoptotic process GO:0006915 381 0.013
Human
prostate gland epithelium morphogenesis GO:0060740 2 0.013
regulation of response to wounding GO:1903034 69 0.013
regulation of leukocyte chemotaxis GO:0002688 12 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of developmental process GO:0051094 283 0.013
brain development GO:0007420 247 0.013
muscle structure development GO:0061061 87 0.013
regulation of tube size GO:0035150 89 0.013
protein complex subunit organization GO:0071822 302 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
neutrophil chemotaxis GO:0030593 11 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of ion homeostasis GO:2000021 63 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
neuron development GO:0048666 286 0.013
multi multicellular organism process GO:0044706 138 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
cytoplasmic transport GO:0016482 115 0.013
negative regulation of immune response GO:0050777 15 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
protein complex biogenesis GO:0070271 263 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
camp metabolic process GO:0046058 63 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
positive regulation of immune system process GO:0002684 90 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
cellular response to oxidative stress GO:0034599 76 0.012
response to hypoxia GO:0001666 231 0.012
response to activity GO:0014823 73 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
secretion by cell GO:0032940 248 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of transport GO:0051050 245 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of phagocytosis engulfment GO:0060099 4 0.012
cation homeostasis GO:0055080 195 0.012
leukocyte chemotaxis GO:0030595 22 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
positive regulation of interleukin 1 alpha production GO:0032730 1 0.012
regulation of interferon gamma production GO:0032649 3 0.012
amide transport GO:0042886 105 0.012
positive regulation of t cell mediated immunity GO:0002711 4 0.012
blood vessel development GO:0001568 69 0.012
positive regulation of biosynthetic process GO:0009891 319 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
regulation of defense response GO:0031347 68 0.011
positive regulation of leukocyte chemotaxis GO:0002690 10 0.011
positive regulation of tolerance induction GO:0002645 1 0.011
regulation of leukocyte migration GO:0002685 24 0.011
positive regulation of leukocyte migration GO:0002687 21 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
response to peptide hormone GO:0043434 278 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
interleukin 1 alpha production GO:0032610 1 0.011
response to camp GO:0051591 91 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
positive regulation of calcium ion transport GO:0051928 36 0.011
gamete generation GO:0007276 124 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
calcium ion transport into cytosol GO:0060402 38 0.011
regulation of cellular localization GO:0060341 263 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
carbohydrate homeostasis GO:0033500 75 0.011
divalent metal ion transport GO:0070838 132 0.011
regulation of interleukin 1 beta secretion GO:0050706 3 0.011
calcium ion homeostasis GO:0055074 162 0.011
skeletal muscle tissue development GO:0007519 31 0.011
response to ionizing radiation GO:0010212 59 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
response to vitamin k GO:0032571 4 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
positive regulation of cytokine biosynthetic process GO:0042108 1 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
regulation of hormone levels GO:0010817 187 0.010
interferon gamma production GO:0032609 3 0.010
interleukin 1 secretion GO:0050701 3 0.010
multicellular organismal homeostasis GO:0048871 49 0.010
cytokine biosynthetic process GO:0042089 3 0.010
positive regulation of leukocyte mediated immunity GO:0002705 13 0.010
regulation of transcription dna templated GO:0006355 374 0.010
defense response to gram positive bacterium GO:0050830 2 0.010
regulation of signal transduction GO:0009966 318 0.010
positive regulation of molecular function GO:0044093 230 0.010
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.010

Ifit3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017
eye and adnexa disease DOID:1492 0 0.017
sensory system disease DOID:0050155 0 0.017
retinal disease DOID:5679 0 0.014
glucose metabolism disease DOID:4194 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
disease of metabolism DOID:0014667 0 0.011
type 1 diabetes mellitus DOID:9744 0 0.011
diabetes mellitus DOID:9351 0 0.011