Rattus norvegicus

308 known processes

Il18

interleukin 18

(Aliases: IL-18)

Il18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to stress GO:0033554 269 0.443
intracellular signal transduction GO:0035556 314 0.345
response to oxidative stress GO:0006979 186 0.320
cellular response to endogenous stimulus GO:0071495 377 0.313
regulation of phosphorus metabolic process GO:0051174 349 0.297
response to biotic stimulus GO:0009607 226 0.289
cellular component biogenesis GO:0044085 368 0.279
regulation of phosphate metabolic process GO:0019220 349 0.268
cellular response to hormone stimulus GO:0032870 247 0.250
protein complex subunit organization GO:0071822 302 0.242
cellular response to organonitrogen compound GO:0071417 197 0.219
defense response GO:0006952 194 0.212
monocarboxylic acid metabolic process GO:0032787 152 0.207
response to purine containing compound GO:0014074 126 0.205
response to metal ion GO:0010038 253 0.203
response to inorganic substance GO:0010035 377 0.203
secretion GO:0046903 307 0.200
organic substance catabolic process GO:1901575 316 0.195
response to extracellular stimulus GO:0009991 380 0.194
programmed cell death GO:0012501 392 0.190
regulation of programmed cell death GO:0043067 341 0.185
regulation of apoptotic process GO:0042981 335 0.177
behavior GO:0007610 205 0.175
positive regulation of phosphate metabolic process GO:0045937 262 0.175
organophosphate metabolic process GO:0019637 370 0.174
negative regulation of response to stimulus GO:0048585 155 0.168
reproductive structure development GO:0048608 128 0.168
negative regulation of metabolic process GO:0009892 331 0.158
response to wounding GO:0009611 254 0.154
positive regulation of t cell migration GO:2000406 1 0.153
single organism biosynthetic process GO:0044711 342 0.153
positive regulation of cellular protein metabolic process GO:0032270 167 0.147
positive regulation of cell communication GO:0010647 271 0.146
lipid biosynthetic process GO:0008610 128 0.143
tissue development GO:0009888 252 0.142
regulation of catalytic activity GO:0050790 304 0.141
protein phosphorylation GO:0006468 345 0.140
apoptotic process GO:0006915 381 0.139
vesicle mediated transport GO:0016192 181 0.138
aging GO:0007568 241 0.137
rna metabolic process GO:0016070 406 0.137
negative regulation of cell death GO:0060548 229 0.137
response to molecule of bacterial origin GO:0002237 194 0.136
regulation of protein modification process GO:0031399 194 0.135
response to estrogen GO:0043627 232 0.134
macromolecular complex assembly GO:0065003 273 0.131
cellular response to nitrogen compound GO:1901699 210 0.131
cellular component assembly GO:0022607 360 0.130
regulation of b cell mediated immunity GO:0002712 2 0.129
inflammatory response GO:0006954 150 0.126
nucleoside metabolic process GO:0009116 179 0.124
negative regulation of signaling GO:0023057 157 0.124
protein complex biogenesis GO:0070271 263 0.124
response to zinc ion GO:0010043 39 0.122
regulation of cellular component organization GO:0051128 368 0.122
positive regulation of transport GO:0051050 245 0.121
aromatic compound catabolic process GO:0019439 168 0.121
carbohydrate derivative catabolic process GO:1901136 147 0.120
regulation of cellular protein metabolic process GO:0032268 267 0.119
regulation of t cell migration GO:2000404 1 0.119
positive regulation of cellular biosynthetic process GO:0031328 295 0.118
regulation of system process GO:0044057 208 0.118
response to external biotic stimulus GO:0043207 221 0.117
response to corticosteroid GO:0031960 235 0.117
cellular response to molecule of bacterial origin GO:0071219 56 0.117
response to transition metal nanoparticle GO:1990267 122 0.117
muscle system process GO:0003012 115 0.115
cellular response to organic cyclic compound GO:0071407 202 0.114
response to peptide GO:1901652 292 0.113
positive regulation of response to stimulus GO:0048584 285 0.113
cellular catabolic process GO:0044248 295 0.110
single organism catabolic process GO:0044712 283 0.110
negative regulation of programmed cell death GO:0043069 183 0.109
cell cell signaling GO:0007267 335 0.108
nucleobase containing small molecule metabolic process GO:0055086 316 0.107
protein complex assembly GO:0006461 263 0.105
regulation of lymphocyte migration GO:2000401 1 0.104
cellular response to lipid GO:0071396 201 0.103
negative regulation of macromolecule metabolic process GO:0010605 260 0.102
positive regulation of protein metabolic process GO:0051247 178 0.101
cellular response to peptide hormone stimulus GO:0071375 120 0.100
actin filament based process GO:0030029 86 0.098
cellular response to hydroperoxide GO:0071447 2 0.095
regulation of protein phosphorylation GO:0001932 183 0.093
response to glucocorticoid GO:0051384 223 0.092
response to organophosphorus GO:0046683 102 0.092
organonitrogen compound catabolic process GO:1901565 179 0.091
positive regulation of cell death GO:0010942 184 0.088
cognition GO:0050890 92 0.087
response to nutrient GO:0007584 248 0.087
immune system process GO:0002376 204 0.086
negative regulation of gene expression GO:0010629 199 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.084
membrane organization GO:0061024 94 0.084
neurological system process GO:0050877 219 0.083
regulation of mononuclear cell proliferation GO:0032944 26 0.083
reproductive system development GO:0061458 128 0.082
lipid metabolic process GO:0006629 283 0.082
positive regulation of multicellular organismal process GO:0051240 387 0.080
glycosyl compound catabolic process GO:1901658 126 0.080
transcription dna templated GO:0006351 377 0.079
cytoskeleton organization GO:0007010 111 0.079
cellular response to oxygen containing compound GO:1901701 386 0.079
purine nucleoside triphosphate metabolic process GO:0009144 141 0.078
catabolic process GO:0009056 351 0.078
negative regulation of multicellular organismal process GO:0051241 203 0.077
secretion by cell GO:0032940 248 0.077
response to oxygen levels GO:0070482 265 0.077
negative regulation of apoptotic process GO:0043066 181 0.076
regulation of cellular localization GO:0060341 263 0.076
central nervous system development GO:0007417 311 0.075
development of primary sexual characteristics GO:0045137 107 0.075
anatomical structure morphogenesis GO:0009653 298 0.074
carboxylic acid metabolic process GO:0019752 289 0.074
macromolecular complex subunit organization GO:0043933 339 0.074
oxoacid metabolic process GO:0043436 290 0.073
small molecule biosynthetic process GO:0044283 124 0.073
reactive oxygen species metabolic process GO:0072593 37 0.072
response to estradiol GO:0032355 164 0.071
mononuclear cell proliferation GO:0032943 29 0.069
lymphocyte activation GO:0046649 43 0.069
response to cytokine GO:0034097 215 0.068
response to temperature stimulus GO:0009266 94 0.068
response to bacterium GO:0009617 200 0.067
single organism intracellular transport GO:1902582 166 0.066
regulation of rna biosynthetic process GO:2001141 381 0.066
regulation of molecular function GO:0065009 398 0.066
cell activation GO:0001775 97 0.066
organic acid metabolic process GO:0006082 292 0.066
nucleoside phosphate metabolic process GO:0006753 283 0.065
negative regulation of neutrophil apoptotic process GO:0033030 3 0.065
cellular response to external stimulus GO:0071496 118 0.065
cellular ketone metabolic process GO:0042180 51 0.064
nitrogen compound transport GO:0071705 229 0.064
hormone transport GO:0009914 121 0.064
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.064
positive regulation of molecular function GO:0044093 230 0.063
cellular response to oxidative stress GO:0034599 76 0.063
regulation of cell proliferation GO:0042127 359 0.063
hormone secretion GO:0046879 115 0.062
response to ketone GO:1901654 182 0.062
nucleoside catabolic process GO:0009164 126 0.061
cellular response to insulin stimulus GO:0032869 81 0.061
negative regulation of phosphorus metabolic process GO:0010563 80 0.060
t cell migration GO:0072678 2 0.060
endocytosis GO:0006897 84 0.059
cell motility GO:0048870 202 0.059
nucleotide catabolic process GO:0009166 139 0.058
organic cyclic compound catabolic process GO:1901361 175 0.058
response to peptide hormone GO:0043434 278 0.058
cellular chemical homeostasis GO:0055082 247 0.058
cellular metal ion homeostasis GO:0006875 172 0.058
regulation of intracellular signal transduction GO:1902531 218 0.058
response to growth factor GO:0070848 189 0.058
negative regulation of cellular biosynthetic process GO:0031327 161 0.058
response to hydrogen peroxide GO:0042542 89 0.056
ribonucleoside metabolic process GO:0009119 174 0.056
response to other organism GO:0051707 220 0.056
purine nucleoside metabolic process GO:0042278 169 0.056
positive regulation of secretion GO:0051047 140 0.056
icosanoid biosynthetic process GO:0046456 18 0.056
regulation of t cell proliferation GO:0042129 17 0.054
regulation of immunoglobulin production GO:0002637 4 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.054
calcium ion homeostasis GO:0055074 162 0.054
cell type specific apoptotic process GO:0097285 134 0.054
response to hypoxia GO:0001666 231 0.053
cation transport GO:0006812 382 0.053
neuron differentiation GO:0030182 368 0.053
cellular response to reactive oxygen species GO:0034614 55 0.052
signal release GO:0023061 145 0.052
cellular lipid metabolic process GO:0044255 208 0.052
regulation of secretion GO:0051046 224 0.052
response to nutrient levels GO:0031667 370 0.051
regulation of response to wounding GO:1903034 69 0.051
regulation of vesicle mediated transport GO:0060627 81 0.051
myeloid cell apoptotic process GO:0033028 6 0.050
gonad development GO:0008406 104 0.050
cell projection organization GO:0030030 302 0.050
response to amino acid GO:0043200 75 0.050
nucleotide metabolic process GO:0009117 279 0.049
positive regulation of signaling GO:0023056 270 0.049
regulation of protein metabolic process GO:0051246 289 0.049
epithelium development GO:0060429 96 0.049
negative regulation of biosynthetic process GO:0009890 168 0.048
response to alkaloid GO:0043279 132 0.048
homeostatic process GO:0042592 331 0.047
multi organism reproductive process GO:0044703 262 0.047
protein oligomerization GO:0051259 191 0.047
ribose phosphate metabolic process GO:0019693 235 0.047
regulation of signal transduction GO:0009966 318 0.046
response to axon injury GO:0048678 59 0.046
regulation of cell activation GO:0050865 50 0.046
single organism reproductive process GO:0044702 297 0.046
positive regulation of catalytic activity GO:0043085 184 0.046
ribonucleotide metabolic process GO:0009259 231 0.045
divalent inorganic cation transport GO:0072511 134 0.045
regulation of reactive oxygen species metabolic process GO:2000377 26 0.045
unsaturated fatty acid metabolic process GO:0033559 39 0.045
regulation of multicellular organismal development GO:2000026 376 0.044
regulation of endocytosis GO:0030100 42 0.044
reactive nitrogen species metabolic process GO:2001057 1 0.044
purine ribonucleotide catabolic process GO:0009154 136 0.044
regulation of body fluid levels GO:0050878 90 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.043
mapk cascade GO:0000165 140 0.043
ribonucleoside triphosphate metabolic process GO:0009199 141 0.043
negative regulation of cell proliferation GO:0008285 119 0.042
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.042
response to ethanol GO:0045471 162 0.042
positive regulation of biosynthetic process GO:0009891 319 0.042
wound healing GO:0042060 122 0.041
response to carbohydrate GO:0009743 183 0.041
positive regulation of programmed cell death GO:0043068 157 0.041
brain development GO:0007420 247 0.041
negative regulation of rna biosynthetic process GO:1902679 118 0.041
organonitrogen compound biosynthetic process GO:1901566 167 0.040
regulation of cell cycle g1 s phase transition GO:1902806 7 0.040
cellular component morphogenesis GO:0032989 155 0.040
response to reactive oxygen species GO:0000302 120 0.040
amide transport GO:0042886 105 0.040
blood circulation GO:0008015 183 0.039
regulation of cell cycle GO:0051726 73 0.039
organophosphate catabolic process GO:0046434 148 0.039
developmental process involved in reproduction GO:0003006 159 0.039
cell morphogenesis involved in differentiation GO:0000904 119 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
regulation of secretion by cell GO:1903530 208 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
intracellular transport GO:0046907 185 0.038
cytosolic calcium ion homeostasis GO:0051480 140 0.038
heterocycle catabolic process GO:0046700 167 0.038
leukocyte activation GO:0045321 76 0.038
purine ribonucleotide metabolic process GO:0009150 227 0.038
glial cell development GO:0021782 19 0.038
cellular component movement GO:0006928 248 0.037
chemical homeostasis GO:0048878 292 0.037
regulation of response to external stimulus GO:0032101 106 0.037
regulation of hormone levels GO:0010817 187 0.037
regulation of rna metabolic process GO:0051252 391 0.037
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.037
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.037
nucleoside triphosphate metabolic process GO:0009141 144 0.037
head development GO:0060322 247 0.037
organelle organization GO:0006996 266 0.037
regulation of immunoglobulin mediated immune response GO:0002889 2 0.036
cellular nitrogen compound catabolic process GO:0044270 163 0.036
cellular response to peptide GO:1901653 133 0.036
positive regulation of response to external stimulus GO:0032103 51 0.036
purine containing compound metabolic process GO:0072521 253 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
cellular amine metabolic process GO:0044106 38 0.035
ribonucleoside catabolic process GO:0042454 126 0.035
positive regulation of protein phosphorylation GO:0001934 135 0.035
activation of protein kinase b activity GO:0032148 3 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
response to decreased oxygen levels GO:0036293 237 0.035
nucleic acid templated transcription GO:0097659 379 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
icosanoid metabolic process GO:0006690 38 0.035
positive regulation of phosphorylation GO:0042327 177 0.034
purine ribonucleoside metabolic process GO:0046128 168 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
purine containing compound catabolic process GO:0072523 138 0.034
negative regulation of rna metabolic process GO:0051253 123 0.034
regulation of cell development GO:0060284 263 0.034
synaptic growth at neuromuscular junction GO:0051124 1 0.034
negative regulation of cell communication GO:0010648 158 0.034
peptidyl amino acid modification GO:0018193 126 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
cell cycle phase transition GO:0044770 21 0.033
regulation of phosphorylation GO:0042325 248 0.033
nucleoside triphosphate catabolic process GO:0009143 123 0.033
g protein coupled receptor signaling pathway GO:0007186 242 0.033
peptidyl serine phosphorylation GO:0018105 33 0.032
smooth muscle cell proliferation GO:0048659 77 0.032
proteolysis GO:0006508 175 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
positive regulation of intracellular signal transduction GO:1902533 138 0.032
learning GO:0007612 33 0.032
regulation of cell differentiation GO:0045595 320 0.032
locomotion GO:0040011 237 0.032
negative regulation of signal transduction GO:0009968 83 0.031
regulation of nervous system development GO:0051960 264 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
negative regulation of neuron apoptotic process GO:0043524 45 0.031
positive regulation of lymphocyte migration GO:2000403 1 0.031
positive regulation of cellular component organization GO:0051130 200 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
positive regulation of hydrolase activity GO:0051345 86 0.030
peptidyl tyrosine phosphorylation GO:0018108 72 0.030
regulation of neurogenesis GO:0050767 247 0.029
regulation of leukocyte proliferation GO:0070663 26 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.029
negative regulation of cellular component organization GO:0051129 83 0.029
axonogenesis GO:0007409 71 0.029
neuron death GO:0070997 127 0.029
activation of protein kinase activity GO:0032147 47 0.029
single organism cellular localization GO:1902580 102 0.029
positive regulation of protein modification process GO:0031401 142 0.029
amine metabolic process GO:0009308 38 0.029
response to electrical stimulus GO:0051602 56 0.028
cellular homeostasis GO:0019725 252 0.028
single organism behavior GO:0044708 130 0.028
positive regulation of cell motility GO:2000147 97 0.028
regulation of transcription dna templated GO:0006355 374 0.028
localization of cell GO:0051674 202 0.028
cell cycle GO:0007049 101 0.028
axis specification GO:0009798 4 0.028
learning or memory GO:0007611 90 0.028
ribonucleotide catabolic process GO:0009261 136 0.028
immune response regulating signaling pathway GO:0002764 19 0.028
reproductive process GO:0022414 372 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
negative regulation of cellular protein metabolic process GO:0032269 106 0.026
rna biosynthetic process GO:0032774 380 0.026
response to vitamin GO:0033273 131 0.026
divalent metal ion transport GO:0070838 132 0.026
response to heat GO:0009408 60 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
ras protein signal transduction GO:0007265 29 0.026
regulation of lipid metabolic process GO:0019216 68 0.026
purine nucleoside catabolic process GO:0006152 124 0.026
positive regulation of nervous system development GO:0051962 178 0.026
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
peptide secretion GO:0002790 86 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
stress activated protein kinase signaling cascade GO:0031098 37 0.025
fatty acid derivative metabolic process GO:1901568 38 0.025
regulation of cellular component movement GO:0051270 150 0.025
cellular response to interferon gamma GO:0071346 14 0.025
olfactory behavior GO:0042048 2 0.025
cellular cation homeostasis GO:0030003 180 0.025
signal transduction by phosphorylation GO:0023014 144 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
positive regulation of signal transduction GO:0009967 175 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.024
neuron projection development GO:0031175 273 0.024
taxis GO:0042330 67 0.024
regulation of metal ion transport GO:0010959 118 0.024
regulation of cellular catabolic process GO:0031329 101 0.024
synaptic transmission GO:0007268 235 0.024
cation homeostasis GO:0055080 195 0.024
response to lipopolysaccharide GO:0032496 191 0.024
regulation of hydrolase activity GO:0051336 143 0.024
response to insulin GO:0032868 133 0.024
neuron development GO:0048666 286 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.023
response to mechanical stimulus GO:0009612 134 0.023
multicellular organism reproduction GO:0032504 233 0.023
ribonucleoside monophosphate metabolic process GO:0009161 88 0.023
ion homeostasis GO:0050801 212 0.023
response to hexose GO:0009746 144 0.023
gtp catabolic process GO:0006184 71 0.023
cell cycle process GO:0022402 57 0.023
regulation of anatomical structure size GO:0090066 135 0.023
fatty acid metabolic process GO:0006631 99 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
cellular response to steroid hormone stimulus GO:0071383 93 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.022
negative regulation of homeostatic process GO:0032845 47 0.022
nucleoside monophosphate metabolic process GO:0009123 93 0.022
metal ion transport GO:0030001 289 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
olfactory learning GO:0008355 1 0.022
regulation of lymphocyte proliferation GO:0050670 26 0.022
positive regulation of gene expression GO:0010628 244 0.022
negative regulation of response to external stimulus GO:0032102 37 0.022
carbohydrate metabolic process GO:0005975 130 0.022
positive regulation of cell development GO:0010720 176 0.022
single organism organelle organization GO:1902589 180 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
cell part morphogenesis GO:0032990 123 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
anion transport GO:0006820 178 0.021
regulation of proteasomal protein catabolic process GO:0061136 4 0.021
cellular macromolecular complex assembly GO:0034622 58 0.021
regulation of ion transport GO:0043269 245 0.021
regulation of nucleoside metabolic process GO:0009118 66 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
regulation of leukocyte activation GO:0002694 45 0.021
response to interferon gamma GO:0034341 20 0.021
peptidyl tyrosine modification GO:0018212 72 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.021
positive regulation of smooth muscle cell migration GO:0014911 27 0.021
macromolecule localization GO:0033036 252 0.021
organic acid biosynthetic process GO:0016053 83 0.020
positive regulation of nucleotide metabolic process GO:0045981 91 0.020
regulation of response to stress GO:0080134 126 0.020
immune response GO:0006955 104 0.020
protein secretion GO:0009306 34 0.020
epithelial cell differentiation GO:0030855 71 0.020
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
positive regulation of defense response GO:0031349 37 0.020
cellular ion homeostasis GO:0006873 184 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
positive regulation of locomotion GO:0040017 102 0.020
digestive system development GO:0055123 41 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
regulation of mapk cascade GO:0043408 116 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
response to isoquinoline alkaloid GO:0014072 28 0.019
maintenance of location GO:0051235 17 0.019
regulation of immune response GO:0050776 55 0.019
positive regulation of catabolic process GO:0009896 78 0.019
lymphocyte proliferation GO:0046651 29 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
reproduction GO:0000003 245 0.019
programmed necrotic cell death GO:0097300 2 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
regulation of cytokine production GO:0001817 56 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
response to glucose GO:0009749 136 0.018
positive regulation of developmental process GO:0051094 283 0.018
single organism membrane organization GO:0044802 74 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
cytoplasmic transport GO:0016482 115 0.018
defense response to gram positive bacterium GO:0050830 2 0.018
regulation of catabolic process GO:0009894 113 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
digestive tract development GO:0048565 39 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
cell chemotaxis GO:0060326 31 0.017
regulation of synaptic plasticity GO:0048167 70 0.017
regulation of locomotion GO:0040012 148 0.017
negative regulation of growth GO:0045926 37 0.017
gliogenesis GO:0042063 93 0.017
chemotaxis GO:0006935 66 0.017
response to camp GO:0051591 91 0.017
sensory perception GO:0007600 101 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
calcium ion transport GO:0006816 131 0.017
response to acid chemical GO:0001101 222 0.017
dna metabolic process GO:0006259 96 0.017
regulation of transferase activity GO:0051338 123 0.017
positive regulation of leukocyte proliferation GO:0070665 20 0.017
leukocyte proliferation GO:0070661 29 0.017
acute inflammatory response GO:0002526 58 0.017
b cell differentiation GO:0030183 2 0.017
positive regulation of cell migration GO:0030335 96 0.017
cell migration GO:0016477 197 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
metal ion homeostasis GO:0055065 186 0.017
hemostasis GO:0007599 26 0.017
regulation of inflammatory response GO:0050727 48 0.017
cell projection morphogenesis GO:0048858 123 0.017
memory GO:0007613 54 0.017
protein autophosphorylation GO:0046777 66 0.017
response to ammonium ion GO:0060359 71 0.016
tissue remodeling GO:0048771 40 0.016
negative regulation of molecular function GO:0044092 133 0.016
purine nucleoside monophosphate catabolic process GO:0009128 55 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
cellular response to biotic stimulus GO:0071216 59 0.016
neurotrophin trk receptor signaling pathway GO:0048011 10 0.016
sex differentiation GO:0007548 113 0.016
leukocyte migration GO:0050900 38 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
phospholipid metabolic process GO:0006644 61 0.016
regulation of immune system process GO:0002682 123 0.015
t cell activation GO:0042110 29 0.015
cellular response to acid chemical GO:0071229 75 0.015
atp metabolic process GO:0046034 72 0.015
gtp metabolic process GO:0046039 72 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
smooth muscle cell migration GO:0014909 36 0.015
glial cell differentiation GO:0010001 65 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of cell cycle process GO:0010564 31 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cell cycle g1 s phase transition GO:0044843 13 0.015
positive regulation of immune system process GO:0002684 90 0.015
sensory perception of pain GO:0019233 73 0.015
actin filament bundle assembly GO:0051017 19 0.015
response to monosaccharide GO:0034284 159 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
cation transmembrane transport GO:0098655 263 0.015
muscle cell proliferation GO:0033002 84 0.015
regulation of membrane potential GO:0042391 110 0.015
muscle structure development GO:0061061 87 0.015
negative regulation of developmental process GO:0051093 125 0.014

Il18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
connective tissue disease DOID:65 0 0.022