Rattus norvegicus

29 known processes

Il2rb

interleukin 2 receptor, beta

(Aliases: IL2RBC)

Il2rb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 61 0.761
immune response GO:0006955 104 0.640
positive regulation of cytokine production GO:0001819 42 0.574
eosinophil migration GO:0072677 3 0.553
t cell migration GO:0072678 2 0.514
regulation of cytokine production GO:0001817 56 0.470
cytosolic calcium ion homeostasis GO:0051480 140 0.457
regulation of necroptotic process GO:0060544 2 0.453
t cell chemotaxis GO:0010818 2 0.418
neutrophil migration GO:1990266 12 0.413
myeloid leukocyte activation GO:0002274 36 0.390
leukocyte activation GO:0045321 76 0.388
defense response GO:0006952 194 0.386
eosinophil chemotaxis GO:0048245 3 0.368
positive regulation of locomotion GO:0040017 102 0.366
immune system process GO:0002376 204 0.351
regulation of cell differentiation GO:0045595 320 0.342
regulation of cell activation GO:0050865 50 0.338
positive regulation of necroptotic process GO:0060545 2 0.336
leukocyte activation involved in immune response GO:0002366 16 0.335
t cell activation GO:0042110 29 0.328
response to cytokine GO:0034097 215 0.317
cellular ion homeostasis GO:0006873 184 0.301
cell activation GO:0001775 97 0.297
regulation of homeostatic process GO:0032844 101 0.290
positive regulation of leukocyte differentiation GO:1902107 13 0.290
divalent metal ion transport GO:0070838 132 0.287
lymphocyte chemotaxis GO:0048247 3 0.285
response to other organism GO:0051707 220 0.279
macrophage chemotaxis GO:0048246 2 0.266
response to oxidative stress GO:0006979 186 0.265
cellular metal ion homeostasis GO:0006875 172 0.259
glycerolipid metabolic process GO:0046486 67 0.253
t cell proliferation GO:0042098 19 0.252
leukocyte differentiation GO:0002521 30 0.252
granulocyte migration GO:0097530 16 0.250
regulation of lymphocyte chemotaxis GO:1901623 1 0.244
negative regulation of developmental process GO:0051093 125 0.239
cellular calcium ion homeostasis GO:0006874 160 0.237
lipid metabolic process GO:0006629 283 0.230
positive regulation of multicellular organismal process GO:0051240 387 0.226
response to biotic stimulus GO:0009607 226 0.218
regulation of cellular component movement GO:0051270 150 0.214
cell activation involved in immune response GO:0002263 16 0.212
lymphocyte migration GO:0072676 3 0.211
response to radiation GO:0009314 137 0.198
positive regulation of apoptotic process GO:0043065 154 0.195
cellular homeostasis GO:0019725 252 0.195
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 5 0.191
cellular response to lipopolysaccharide GO:0071222 55 0.191
cytokine secretion GO:0050663 15 0.185
positive regulation of cell death GO:0010942 184 0.185
mast cell migration GO:0097531 4 0.185
cytokine mediated signaling pathway GO:0019221 43 0.179
apoptotic process GO:0006915 381 0.178
regulation of cellular localization GO:0060341 263 0.177
positive regulation of leukocyte activation GO:0002696 30 0.176
osteoclast differentiation GO:0030316 11 0.175
metal ion homeostasis GO:0055065 186 0.173
divalent inorganic cation transport GO:0072511 134 0.166
response to external biotic stimulus GO:0043207 221 0.166
cellular response to cytokine stimulus GO:0071345 127 0.162
positive regulation of interleukin 1 alpha production GO:0032730 1 0.154
myeloid leukocyte differentiation GO:0002573 20 0.152
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.151
regulation of cell proliferation GO:0042127 359 0.147
positive regulation of immune system process GO:0002684 90 0.147
response to lipopolysaccharide GO:0032496 191 0.146
positive regulation of cell activation GO:0050867 34 0.144
regulation of molecular function GO:0065009 398 0.143
leukocyte cell cell adhesion GO:0007159 4 0.141
negative regulation of neutrophil apoptotic process GO:0033030 3 0.141
cellular chemical homeostasis GO:0055082 247 0.138
cellular response to lipid GO:0071396 201 0.138
positive regulation of response to stimulus GO:0048584 285 0.136
cellular cation homeostasis GO:0030003 180 0.135
divalent inorganic cation homeostasis GO:0072507 165 0.135
lymphocyte activation GO:0046649 43 0.132
nitrogen compound transport GO:0071705 229 0.131
positive regulation of cellular component movement GO:0051272 102 0.130
b cell activation involved in immune response GO:0002312 1 0.129
regulation of multicellular organismal development GO:2000026 376 0.128
negative regulation of response to stimulus GO:0048585 155 0.127
response to bacterium GO:0009617 200 0.126
positive regulation of programmed cell death GO:0043068 157 0.124
immune effector process GO:0002252 53 0.122
response to amino acid GO:0043200 75 0.122
negative regulation of multicellular organismal process GO:0051241 203 0.121
positive regulation of signaling GO:0023056 270 0.120
leukocyte proliferation GO:0070661 29 0.119
cell type specific apoptotic process GO:0097285 134 0.117
fatty acid derivative metabolic process GO:1901568 38 0.116
regulation of programmed cell death GO:0043067 341 0.115
response to ketone GO:1901654 182 0.114
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.112
positive regulation of leukocyte migration GO:0002687 21 0.110
positive regulation of cellular biosynthetic process GO:0031328 295 0.110
homeostatic process GO:0042592 331 0.108
t cell differentiation GO:0030217 9 0.108
regulation of t cell activation GO:0050863 23 0.106
response to virus GO:0009615 17 0.106
chronic inflammatory response GO:0002544 16 0.104
innate immune response GO:0045087 35 0.103
response to molecule of bacterial origin GO:0002237 194 0.102
negative regulation of immune system process GO:0002683 39 0.102
response to transforming growth factor beta GO:0071559 46 0.101
regulation of cellular protein metabolic process GO:0032268 267 0.098
response to glucocorticoid GO:0051384 223 0.097
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.097
response to inorganic substance GO:0010035 377 0.096
positive regulation of myeloid leukocyte differentiation GO:0002763 7 0.096
organophosphate metabolic process GO:0019637 370 0.095
cellular response to tumor necrosis factor GO:0071356 46 0.095
cellular divalent inorganic cation homeostasis GO:0072503 162 0.094
cation homeostasis GO:0055080 195 0.094
cellular response to molecule of bacterial origin GO:0071219 56 0.094
regulation of rna metabolic process GO:0051252 391 0.093
positive regulation of cell development GO:0010720 176 0.093
negative regulation of cell death GO:0060548 229 0.092
positive regulation of cell motility GO:2000147 97 0.091
regulation of protein transport GO:0051223 68 0.091
amide transport GO:0042886 105 0.090
response to corticosteroid GO:0031960 235 0.089
leukocyte mediated immunity GO:0002443 28 0.088
fever generation GO:0001660 9 0.088
intracellular signal transduction GO:0035556 314 0.087
angioblast cell migration GO:0035476 1 0.087
icosanoid metabolic process GO:0006690 38 0.086
reproductive process GO:0022414 372 0.086
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.085
neutrophil chemotaxis GO:0030593 11 0.085
regulation of granulocyte chemotaxis GO:0071622 8 0.084
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.084
positive regulation of cell migration GO:0030335 96 0.084
nucleoside phosphate metabolic process GO:0006753 283 0.084
regulation of cell motility GO:2000145 131 0.083
regulation of cell killing GO:0031341 12 0.082
cation transport GO:0006812 382 0.082
proteolysis GO:0006508 175 0.082
aging GO:0007568 241 0.081
inflammatory response to antigenic stimulus GO:0002437 18 0.081
positive regulation of lymphocyte activation GO:0051251 25 0.081
cellular amino acid metabolic process GO:0006520 107 0.079
regulation of calcium ion transport GO:0051924 77 0.078
regulation of neurogenesis GO:0050767 247 0.078
regulation of immune system process GO:0002682 123 0.078
single organism organelle organization GO:1902589 180 0.078
programmed cell death GO:0012501 392 0.077
neuron differentiation GO:0030182 368 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.076
regulation of regulatory t cell differentiation GO:0045589 2 0.075
response to reactive oxygen species GO:0000302 120 0.075
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.074
negative regulation of apoptotic process GO:0043066 181 0.074
gland development GO:0048732 155 0.073
regulation of myeloid leukocyte differentiation GO:0002761 12 0.073
regulation of ion transport GO:0043269 245 0.073
positive regulation of necrotic cell death GO:0010940 4 0.071
regulation of cell development GO:0060284 263 0.071
mast cell chemotaxis GO:0002551 4 0.071
response to hydrogen peroxide GO:0042542 89 0.071
response to vitamin GO:0033273 131 0.070
regulation of t cell differentiation GO:0045580 7 0.070
response to tumor cell GO:0002347 4 0.069
cellular component biogenesis GO:0044085 368 0.069
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.068
fluorene metabolic process GO:0018917 1 0.067
positive regulation of angiogenesis GO:0045766 28 0.066
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 8 0.066
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.066
single organism catabolic process GO:0044712 283 0.065
ion homeostasis GO:0050801 212 0.065
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.064
positive regulation of leukocyte chemotaxis GO:0002690 10 0.064
pseudopodium organization GO:0031268 3 0.064
inflammatory response GO:0006954 150 0.063
response to hypoxia GO:0001666 231 0.062
cellular response to oxygen containing compound GO:1901701 386 0.062
response to nutrient levels GO:0031667 370 0.062
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.061
response to wounding GO:0009611 254 0.061
hematopoietic or lymphoid organ development GO:0048534 36 0.061
hemopoiesis GO:0030097 34 0.061
regulation of leukocyte differentiation GO:1902105 20 0.061
regulation of phosphorylation GO:0042325 248 0.061
positive regulation of cell differentiation GO:0045597 217 0.061
regulation of osteoclast differentiation GO:0045670 8 0.060
negative regulation of cell differentiation GO:0045596 99 0.060
regulation of protein localization GO:0032880 81 0.060
mapk cascade GO:0000165 140 0.059
chemical homeostasis GO:0048878 292 0.059
regulation of neutrophil migration GO:1902622 6 0.059
positive regulation of neurogenesis GO:0050769 165 0.059
regulation of lymphocyte migration GO:2000401 1 0.059
phosphatidylinositol mediated signaling GO:0048015 18 0.058
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.058
negative regulation of cellular metabolic process GO:0031324 281 0.058
chemokine mediated signaling pathway GO:0070098 5 0.058
calcium ion homeostasis GO:0055074 162 0.057
response to estrogen GO:0043627 232 0.057
regulation of response to external stimulus GO:0032101 106 0.057
regulation of cellular ketone metabolic process GO:0010565 27 0.057
carbohydrate derivative metabolic process GO:1901135 346 0.057
regulation of nervous system development GO:0051960 264 0.057
acute inflammatory response GO:0002526 58 0.057
pseudopodium assembly GO:0031269 3 0.055
regulation of leukocyte apoptotic process GO:2000106 5 0.055
ribonucleotide metabolic process GO:0009259 231 0.055
negative regulation of long term synaptic potentiation GO:1900272 1 0.054
regulation of neuron death GO:1901214 115 0.054
positive regulation of cell communication GO:0010647 271 0.054
intracellular transport GO:0046907 185 0.054
regulation of neuron differentiation GO:0045664 208 0.054
regulation of intracellular signal transduction GO:1902531 218 0.053
immunoglobulin mediated immune response GO:0016064 4 0.053
vasculature development GO:0001944 70 0.053
cell cell signaling GO:0007267 335 0.052
leukocyte migration GO:0050900 38 0.052
t helper 1 cell extravasation GO:0035687 1 0.052
cell projection organization GO:0030030 302 0.051
response to high density lipoprotein particle GO:0055099 2 0.051
response to tumor necrosis factor GO:0034612 56 0.051
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.050
cellular response to stress GO:0033554 269 0.050
secretion by cell GO:0032940 248 0.050
single organism biosynthetic process GO:0044711 342 0.050
b cell mediated immunity GO:0019724 4 0.050
regulation of defense response GO:0031347 68 0.050
regulation of alpha beta t cell activation GO:0046634 2 0.050
positive regulation of molecular function GO:0044093 230 0.049
transcription dna templated GO:0006351 377 0.049
muscle contraction GO:0006936 88 0.049
regulation of angiogenesis GO:0045765 39 0.049
negative regulation of t cell apoptotic process GO:0070233 1 0.049
cellular response to hydroperoxide GO:0071447 2 0.049
immune system development GO:0002520 41 0.049
regulation of secretion by cell GO:1903530 208 0.048
activation of phospholipase d activity GO:0031584 2 0.048
negative regulation of metabolic process GO:0009892 331 0.048
positive regulation of biosynthetic process GO:0009891 319 0.048
cellular component movement GO:0006928 248 0.048
regulation of behavior GO:0050795 61 0.047
regulation of cytokine biosynthetic process GO:0042035 3 0.047
circulatory system process GO:0003013 183 0.046
lymphocyte proliferation GO:0046651 29 0.046
positive regulation of signal transduction GO:0009967 175 0.046
regulation of protein modification process GO:0031399 194 0.046
regulation of anatomical structure morphogenesis GO:0022603 141 0.046
single organism intracellular transport GO:1902582 166 0.046
localization of cell GO:0051674 202 0.046
negative regulation of cell proliferation GO:0008285 119 0.046
positive regulation of developmental process GO:0051094 283 0.046
response to ionizing radiation GO:0010212 59 0.045
protein localization GO:0008104 191 0.044
secretion GO:0046903 307 0.044
positive regulation of neuron differentiation GO:0045666 126 0.044
regulation of immunoglobulin production GO:0002637 4 0.044
granulocyte chemotaxis GO:0071621 15 0.044
brain development GO:0007420 247 0.044
signal transduction by phosphorylation GO:0023014 144 0.043
positive regulation of immune response GO:0050778 42 0.043
organic cyclic compound catabolic process GO:1901361 175 0.043
positive regulation of t cell differentiation GO:0045582 6 0.043
regulation of fever generation GO:0031620 6 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
positive regulation of immune effector process GO:0002699 19 0.043
negative regulation of signaling GO:0023057 157 0.043
positive regulation of intracellular signal transduction GO:1902533 138 0.042
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.042
response to growth factor GO:0070848 189 0.041
negative regulation of molecular function GO:0044092 133 0.041
organic acid metabolic process GO:0006082 292 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.041
positive regulation of myeloid cell differentiation GO:0045639 7 0.041
positive regulation of transport GO:0051050 245 0.041
regulation of leukocyte mediated immunity GO:0002703 19 0.041
regulation of apoptotic process GO:0042981 335 0.041
activation of protein kinase b activity GO:0032148 3 0.041
positive regulation of regulatory t cell differentiation GO:0045591 2 0.040
regulation of cell migration GO:0030334 128 0.040
cellular lipid metabolic process GO:0044255 208 0.040
negative regulation of viral process GO:0048525 4 0.040
response to metal ion GO:0010038 253 0.039
response to acid chemical GO:0001101 222 0.039
taxis GO:0042330 67 0.039
regulation of cytokine secretion GO:0050707 11 0.039
synaptic growth at neuromuscular junction GO:0051124 1 0.039
erbb signaling pathway GO:0038127 23 0.039
positive regulation of nervous system development GO:0051962 178 0.039
sequestering of metal ion GO:0051238 9 0.039
cell motility GO:0048870 202 0.038
protein oligomerization GO:0051259 191 0.038
regulation of mononuclear cell proliferation GO:0032944 26 0.038
negative regulation of innate immune response GO:0045824 4 0.038
neuron projection development GO:0031175 273 0.038
response to extracellular stimulus GO:0009991 380 0.038
regulation of protein metabolic process GO:0051246 289 0.038
positive regulation of behavior GO:0048520 38 0.038
negative regulation of homeostatic process GO:0032845 47 0.038
positive regulation of t cell migration GO:2000406 1 0.038
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.038
positive regulation of immunoglobulin production GO:0002639 4 0.038
positive regulation of cell killing GO:0031343 9 0.037
anion transport GO:0006820 178 0.037
response to cholesterol GO:0070723 13 0.037
regulation of response to stress GO:0080134 126 0.037
metanephric tubule morphogenesis GO:0072173 2 0.037
learning or memory GO:0007611 90 0.037
phospholipid metabolic process GO:0006644 61 0.037
oxoacid metabolic process GO:0043436 290 0.037
positive regulation of defense response GO:0031349 37 0.037
organophosphate catabolic process GO:0046434 148 0.036
regulation of adaptive immune response GO:0002819 8 0.036
cellular response to ketone GO:1901655 51 0.036
multicellular organismal homeostasis GO:0048871 49 0.036
positive regulation of osteoclast differentiation GO:0045672 5 0.036
t cell receptor signaling pathway GO:0050852 1 0.036
regulation of signal transduction GO:0009966 318 0.036
regulation of catalytic activity GO:0050790 304 0.036
response to gamma radiation GO:0010332 24 0.035
regulation of phagocytosis engulfment GO:0060099 4 0.035
cellular component assembly GO:0022607 360 0.035
vitamin biosynthetic process GO:0009110 3 0.035
defense response to other organism GO:0098542 17 0.035
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.035
positive regulation of cell proliferation GO:0008284 249 0.035
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.034
macromolecule localization GO:0033036 252 0.034
cell junction assembly GO:0034329 18 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
gamete generation GO:0007276 124 0.034
renal system development GO:0072001 67 0.034
cellular response to biotic stimulus GO:0071216 59 0.034
regulation of protein secretion GO:0050708 28 0.034
positive regulation of response to external stimulus GO:0032103 51 0.034
organ morphogenesis GO:0009887 75 0.033
myeloid leukocyte migration GO:0097529 20 0.033
cellular response to oxidative stress GO:0034599 76 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
establishment of protein localization GO:0045184 141 0.033
wound healing GO:0042060 122 0.033
interleukin 1 biosynthetic process GO:0042222 1 0.033
cytoplasmic transport GO:0016482 115 0.033
regulation of leukocyte migration GO:0002685 24 0.033
cytokine biosynthetic process GO:0042089 3 0.032
interleukin 1 alpha production GO:0032610 1 0.032
regulation of neural precursor cell proliferation GO:2000177 16 0.032
regulation of hormone secretion GO:0046883 106 0.032
response to vitamin k GO:0032571 4 0.032
protein transport GO:0015031 132 0.032
response to alkyl hydroperoxide GO:0033195 1 0.032
sequestering of calcium ion GO:0051208 8 0.032
regulation of dna metabolic process GO:0051052 60 0.032
organelle organization GO:0006996 266 0.032
neuron development GO:0048666 286 0.032
leukocyte apoptotic process GO:0071887 6 0.031
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.031
regulation of transferase activity GO:0051338 123 0.031
response to insulin GO:0032868 133 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
regulation of myeloid cell differentiation GO:0045637 12 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
cellular response to ammonium ion GO:0071242 17 0.031
protein secretion GO:0009306 34 0.031
helper t cell diapedesis GO:0035685 1 0.031
cellular catabolic process GO:0044248 295 0.030
regulation of intracellular transport GO:0032386 65 0.030
response to peptide GO:1901652 292 0.030
positive regulation of chemotaxis GO:0050921 23 0.030
blood vessel development GO:0001568 69 0.030
gliogenesis GO:0042063 93 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
neuron apoptotic process GO:0051402 88 0.030
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.029
olfactory learning GO:0008355 1 0.029
histamine production involved in inflammatory response GO:0002349 3 0.029
programmed necrotic cell death GO:0097300 2 0.029
response to sterol GO:0036314 13 0.029
regulated secretory pathway GO:0045055 17 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
cell chemotaxis GO:0060326 31 0.028
regulation of kinase activity GO:0043549 117 0.028
response to molecule of fungal origin GO:0002238 3 0.028
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.028
regulation of chemotaxis GO:0050920 29 0.028
response to alkaloid GO:0043279 132 0.028
lipid biosynthetic process GO:0008610 128 0.028
negative regulation of neuron death GO:1901215 69 0.028
cellular response to alkyl hydroperoxide GO:0071448 1 0.028
regulation of vasculature development GO:1901342 44 0.028
nucleotide metabolic process GO:0009117 279 0.027
positive regulation of b cell mediated immunity GO:0002714 2 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
epithelium development GO:0060429 96 0.027
positive regulation of lipid kinase activity GO:0090218 2 0.027
response to transition metal nanoparticle GO:1990267 122 0.027
amino acid transmembrane transport GO:0003333 33 0.027
hormone secretion GO:0046879 115 0.027
regulation of locomotion GO:0040012 148 0.027
response to ethanol GO:0045471 162 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.027
lymphocyte activation involved in immune response GO:0002285 3 0.027
antigen receptor mediated signaling pathway GO:0050851 1 0.026
regulation of mast cell chemotaxis GO:0060753 1 0.026
response to mineralocorticoid GO:0051385 49 0.026
histamine secretion involved in inflammatory response GO:0002441 3 0.026
cellular amine metabolic process GO:0044106 38 0.026
helper t cell extravasation GO:0035684 1 0.026
regulation of interleukin 1 production GO:0032652 11 0.026
response to toxic substance GO:0009636 133 0.026
positive regulation of camp metabolic process GO:0030816 31 0.026
regulation of secretion GO:0051046 224 0.026
necroptotic process GO:0070266 2 0.026
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 13 0.026
regulation of lymphocyte activation GO:0051249 34 0.026
cellular response to interleukin 1 GO:0071347 37 0.026
single organism cell adhesion GO:0098602 46 0.026
cell migration GO:0016477 197 0.026
signal transduction in absence of ligand GO:0038034 5 0.026
sensory organ development GO:0007423 74 0.026
transmembrane transport GO:0055085 412 0.026
anatomical structure formation involved in morphogenesis GO:0048646 83 0.026
peptide transport GO:0015833 97 0.026
response to interleukin 1 GO:0070555 55 0.025
regulation of leukocyte chemotaxis GO:0002688 12 0.025
insulin secretion GO:0030073 69 0.025
positive regulation of hydrolase activity GO:0051345 86 0.025
striated muscle contraction GO:0006941 44 0.025
positive regulation of gamma delta t cell activation GO:0046645 1 0.025
locomotion GO:0040011 237 0.025
regulation of homotypic cell cell adhesion GO:0034110 4 0.025
positive regulation of alpha beta t cell activation GO:0046635 2 0.025
sexual reproduction GO:0019953 148 0.025
developmental process involved in reproduction GO:0003006 159 0.025
interleukin 1 production GO:0032612 11 0.025
mononuclear cell proliferation GO:0032943 29 0.025
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.025
positive regulation of neutrophil migration GO:1902624 6 0.025
response to osmotic stress GO:0006970 42 0.025
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
negative regulation of leukocyte apoptotic process GO:2000107 4 0.024
organic substance catabolic process GO:1901575 316 0.024
reactive oxygen species metabolic process GO:0072593 37 0.024
purine containing compound metabolic process GO:0072521 253 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
alcohol metabolic process GO:0006066 77 0.024
eye development GO:0001654 50 0.024
exocytosis GO:0006887 60 0.024
calcium ion transport GO:0006816 131 0.023
hormone transport GO:0009914 121 0.023
protein complex subunit organization GO:0071822 302 0.023
cellular response to nutrient levels GO:0031669 60 0.023
positive regulation of leukocyte degranulation GO:0043302 4 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
regulation of lymphocyte proliferation GO:0050670 26 0.023
regulation of neuron apoptotic process GO:0043523 83 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
negative regulation of cell matrix adhesion GO:0001953 3 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
defense response to virus GO:0051607 9 0.022
neurotrophin trk receptor signaling pathway GO:0048011 10 0.022
behavior GO:0007610 205 0.022
regulation of hydrolase activity GO:0051336 143 0.022
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.022
regulation of immune response GO:0050776 55 0.022
regulation of leukocyte activation GO:0002694 45 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
vascular process in circulatory system GO:0003018 96 0.022
cellular ketone metabolic process GO:0042180 51 0.022
cell communication involved in cardiac conduction GO:0086065 2 0.022
lysosome localization GO:0032418 10 0.021
single organism reproductive process GO:0044702 297 0.021
lymphocyte differentiation GO:0030098 10 0.021
t cell tolerance induction GO:0002517 3 0.021
regulation of metal ion transport GO:0010959 118 0.021
gastrulation GO:0007369 2 0.021
lymphocyte mediated immunity GO:0002449 14 0.021
regulation of peptide secretion GO:0002791 82 0.020
icosanoid biosynthetic process GO:0046456 18 0.020
response to interleukin 13 GO:0035962 3 0.020
regulation of protein kinase activity GO:0045859 105 0.020
response to peptide hormone GO:0043434 278 0.020
positive regulation of leukocyte proliferation GO:0070665 20 0.020
regulation of response to wounding GO:1903034 69 0.020
positive regulation of isotype switching GO:0045830 1 0.020
positive regulation of cytokine biosynthetic process GO:0042108 1 0.020
acute phase response GO:0006953 20 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of immunoglobulin secretion GO:0051023 1 0.020

Il2rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.038
cancer DOID:162 0 0.037
organ system cancer DOID:0050686 0 0.037