Rattus norvegicus

426 known processes

Il6

interleukin 6

(Aliases: Ifnb2,ILg6)

Il6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of fever generation GO:0031622 5 0.953
cellular response to tumor necrosis factor GO:0071356 46 0.898
regulation of fever generation GO:0031620 6 0.889
cellular response to cytokine stimulus GO:0071345 127 0.888
response to lipopolysaccharide GO:0032496 191 0.879
granulocyte migration GO:0097530 16 0.836
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.818
cellular response to lipoteichoic acid GO:0071223 1 0.812
response to biotic stimulus GO:0009607 226 0.810
granulocyte chemotaxis GO:0071621 15 0.806
cellular response to lipopolysaccharide GO:0071222 55 0.780
neutrophil migration GO:1990266 12 0.745
leukocyte migration GO:0050900 38 0.732
neutrophil chemotaxis GO:0030593 11 0.713
positive regulation of leukocyte chemotaxis GO:0002690 10 0.695
regulation of cellular extravasation GO:0002691 2 0.684
response to dexamethasone GO:0071548 49 0.676
cell chemotaxis GO:0060326 31 0.668
cellular response to interleukin 1 GO:0071347 37 0.654
response to tumor necrosis factor GO:0034612 56 0.621
response to oxidative stress GO:0006979 186 0.611
cellular response to molecule of bacterial origin GO:0071219 56 0.599
response to bacterium GO:0009617 200 0.592
response to external biotic stimulus GO:0043207 221 0.586
positive regulation of response to stimulus GO:0048584 285 0.568
response to peptide hormone GO:0043434 278 0.566
response to insulin GO:0032868 133 0.565
cellular response to high density lipoprotein particle stimulus GO:0071403 2 0.561
regulation of intracellular signal transduction GO:1902531 218 0.532
response to cytokine GO:0034097 215 0.531
cellular response to peptide hormone stimulus GO:0071375 120 0.530
cytokine mediated signaling pathway GO:0019221 43 0.525
immune response GO:0006955 104 0.525
response to interleukin 1 GO:0070555 55 0.524
response to high density lipoprotein particle GO:0055099 2 0.514
positive regulation of immune system process GO:0002684 90 0.513
cytokine production GO:0001816 61 0.512
response to peptide GO:1901652 292 0.502
cellular response to hydroperoxide GO:0071447 2 0.499
interleukin 1 biosynthetic process GO:0042222 1 0.491
cellular response to biotic stimulus GO:0071216 59 0.490
response to molecule of bacterial origin GO:0002237 194 0.485
cellular extravasation GO:0045123 5 0.476
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.475
fever generation GO:0001660 9 0.473
diapedesis GO:0050904 1 0.464
t helper 1 cell extravasation GO:0035687 1 0.461
regulation of leukocyte migration GO:0002685 24 0.459
response to glucocorticoid GO:0051384 223 0.453
immune system process GO:0002376 204 0.446
response to corticosteroid GO:0031960 235 0.445
positive regulation of intracellular signal transduction GO:1902533 138 0.445
regulation of leukocyte chemotaxis GO:0002688 12 0.440
positive regulation of cell differentiation GO:0045597 217 0.437
leukocyte chemotaxis GO:0030595 22 0.430
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.429
positive regulation of multicellular organismal process GO:0051240 387 0.407
t cell extravasation GO:0072683 1 0.402
myeloid leukocyte migration GO:0097529 20 0.393
leukocyte activation GO:0045321 76 0.392
response to other organism GO:0051707 220 0.391
response to wounding GO:0009611 254 0.390
cellular response to endogenous stimulus GO:0071495 377 0.376
cellular response to alkyl hydroperoxide GO:0071448 1 0.367
regulation of cellular component movement GO:0051270 150 0.365
positive regulation of leukocyte migration GO:0002687 21 0.364
cellular response to interferon gamma GO:0071346 14 0.363
regulation of t cell migration GO:2000404 1 0.356
regulation of immune system process GO:0002682 123 0.347
cellular response to stress GO:0033554 269 0.343
regulation of lymphocyte chemotaxis GO:1901623 1 0.341
regulation of cytokine production GO:0001817 56 0.329
response to mechanical stimulus GO:0009612 134 0.320
defense response GO:0006952 194 0.320
response to extracellular stimulus GO:0009991 380 0.318
reproductive structure development GO:0048608 128 0.316
regulation of anatomical structure morphogenesis GO:0022603 141 0.315
positive regulation of cell communication GO:0010647 271 0.313
regulation of ion transport GO:0043269 245 0.308
cellular response to peptide GO:1901653 133 0.307
regulation of signal transduction GO:0009966 318 0.306
response to estrogen GO:0043627 232 0.287
response to alkyl hydroperoxide GO:0033195 1 0.287
neuron death GO:0070997 127 0.285
negative regulation of vasculature development GO:1901343 11 0.282
positive regulation of signal transduction GO:0009967 175 0.276
negative regulation of apoptotic process GO:0043066 181 0.270
cellular divalent inorganic cation homeostasis GO:0072503 162 0.268
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.267
regulation of cell motility GO:2000145 131 0.266
response to ketone GO:1901654 182 0.258
positive regulation of locomotion GO:0040017 102 0.256
response to reactive oxygen species GO:0000302 120 0.255
reproductive process GO:0022414 372 0.250
regulation of response to stress GO:0080134 126 0.249
regulation of immune response to tumor cell GO:0002837 3 0.249
regulation of t cell chemotaxis GO:0010819 1 0.244
acute phase response GO:0006953 20 0.243
regulation of cell differentiation GO:0045595 320 0.242
negative regulation of cell death GO:0060548 229 0.240
regulation of immunoglobulin secretion GO:0051023 1 0.239
cellular response to nitrogen compound GO:1901699 210 0.231
response to organophosphorus GO:0046683 102 0.230
inflammatory response GO:0006954 150 0.228
cellular calcium ion homeostasis GO:0006874 160 0.225
intracellular signal transduction GO:0035556 314 0.214
response to interleukin 13 GO:0035962 3 0.211
response to hypoxia GO:0001666 231 0.210
response to nutrient levels GO:0031667 370 0.210
regulation of inflammatory response GO:0050727 48 0.208
positive regulation of signaling GO:0023056 270 0.208
positive regulation of t cell migration GO:2000406 1 0.206
regulation of cell migration GO:0030334 128 0.206
positive regulation of apoptotic process GO:0043065 154 0.203
protein phosphorylation GO:0006468 345 0.201
blood vessel development GO:0001568 69 0.200
positive regulation of cell proliferation GO:0008284 249 0.194
cellular component movement GO:0006928 248 0.192
response to temperature stimulus GO:0009266 94 0.192
t cell chemotaxis GO:0010818 2 0.191
lymphocyte chemotaxis GO:0048247 3 0.191
localization of cell GO:0051674 202 0.190
positive regulation of neurogenesis GO:0050769 165 0.187
regulation of apoptotic process GO:0042981 335 0.187
regulation of response to external stimulus GO:0032101 106 0.186
cellular lipid metabolic process GO:0044255 208 0.184
cellular response to lipoprotein particle stimulus GO:0071402 5 0.183
regulation of angiogenesis GO:0045765 39 0.183
secretion by cell GO:0032940 248 0.182
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 8 0.182
metal ion transport GO:0030001 289 0.182
response to amino acid GO:0043200 75 0.180
regulation of vasculature development GO:1901342 44 0.180
protein complex assembly GO:0006461 263 0.179
regulation of monocyte chemotaxis GO:0090025 3 0.177
cell motility GO:0048870 202 0.177
positive regulation of lymphocyte migration GO:2000403 1 0.176
apoptotic process GO:0006915 381 0.175
temperature homeostasis GO:0001659 17 0.174
tissue development GO:0009888 252 0.173
interleukin 1 alpha biosynthetic process GO:0050719 1 0.173
regulation of protein localization GO:0032880 81 0.173
lipid metabolic process GO:0006629 283 0.171
response to low density lipoprotein particle GO:0055098 4 0.169
mapk cascade GO:0000165 140 0.168
regulation of chemotaxis GO:0050920 29 0.168
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.164
cellular response to oxygen containing compound GO:1901701 386 0.163
macromolecular complex subunit organization GO:0043933 339 0.159
female gonad development GO:0008585 53 0.159
calcium ion homeostasis GO:0055074 162 0.159
response to decreased oxygen levels GO:0036293 237 0.155
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.154
positive regulation of cell migration GO:0030335 96 0.153
response to purine containing compound GO:0014074 126 0.152
response to vitamin d GO:0033280 34 0.152
cellular response to external stimulus GO:0071496 118 0.151
response to nutrient GO:0007584 248 0.149
single organism reproductive process GO:0044702 297 0.148
positive regulation of chemotaxis GO:0050921 23 0.148
multi multicellular organism process GO:0044706 138 0.148
t cell activation GO:0042110 29 0.146
female pregnancy GO:0007565 122 0.146
single organism biosynthetic process GO:0044711 342 0.146
cell migration GO:0016477 197 0.145
establishment of protein localization GO:0045184 141 0.145
cellular response to growth factor stimulus GO:0071363 162 0.145
positive regulation of transport GO:0051050 245 0.144
cytosolic calcium ion homeostasis GO:0051480 140 0.143
regulation of programmed cell death GO:0043067 341 0.141
positive regulation of cell motility GO:2000147 97 0.141
reproductive system development GO:0061458 128 0.140
regulation of behavior GO:0050795 61 0.139
positive regulation of neutrophil migration GO:1902624 6 0.138
homeostatic process GO:0042592 331 0.138
angiogenesis GO:0001525 53 0.137
cellular response to insulin stimulus GO:0032869 81 0.137
interleukin 1 alpha production GO:0032610 1 0.137
regulation of hormone levels GO:0010817 187 0.137
cellular ion homeostasis GO:0006873 184 0.135
positive regulation of cell death GO:0010942 184 0.135
regulation of transcription dna templated GO:0006355 374 0.133
cellular response to vitamin k GO:0071307 1 0.131
positive regulation of response to external stimulus GO:0032103 51 0.128
response to monosaccharide GO:0034284 159 0.128
circulatory system development GO:0072359 134 0.128
embryonic hindlimb morphogenesis GO:0035116 2 0.127
aging GO:0007568 241 0.126
cell activation GO:0001775 97 0.126
regulation of cell development GO:0060284 263 0.126
response to inorganic substance GO:0010035 377 0.125
response to radiation GO:0009314 137 0.125
response to hydrogen peroxide GO:0042542 89 0.124
signal transduction by phosphorylation GO:0023014 144 0.123
cellular cation homeostasis GO:0030003 180 0.122
regulation of cytokine biosynthetic process GO:0042035 3 0.121
hindlimb morphogenesis GO:0035137 2 0.121
chemotaxis GO:0006935 66 0.120
innate immune response GO:0045087 35 0.120
response to ethanol GO:0045471 162 0.120
chronic inflammatory response GO:0002544 16 0.120
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.119
organic substance catabolic process GO:1901575 316 0.119
response to estradiol GO:0032355 164 0.119
negative regulation of blood vessel morphogenesis GO:2000181 10 0.118
oxoacid metabolic process GO:0043436 290 0.117
divalent inorganic cation homeostasis GO:0072507 165 0.117
regulation of catalytic activity GO:0050790 304 0.116
protein oligomerization GO:0051259 191 0.114
regulation of phosphate metabolic process GO:0019220 349 0.114
cellular response to alkaloid GO:0071312 25 0.113
multi organism reproductive process GO:0044703 262 0.113
response to vitamin GO:0033273 131 0.113
regeneration GO:0031099 163 0.112
t helper 1 cell diapedesis GO:0035688 1 0.112
positive regulation of cytokine production GO:0001819 42 0.112
response to carbohydrate GO:0009743 183 0.111
response to oxygen levels GO:0070482 265 0.110
icosanoid biosynthetic process GO:0046456 18 0.110
regulation of protein metabolic process GO:0051246 289 0.109
regulation of leukocyte activation GO:0002694 45 0.109
cellular response to organic cyclic compound GO:0071407 202 0.108
reactive oxygen species biosynthetic process GO:1903409 8 0.108
carboxylic acid metabolic process GO:0019752 289 0.108
wound healing GO:0042060 122 0.108
vitamin d biosynthetic process GO:0042368 2 0.107
response to camp GO:0051591 91 0.107
regulation of multicellular organismal development GO:2000026 376 0.107
positive regulation of protein metabolic process GO:0051247 178 0.107
locomotion GO:0040011 237 0.106
positive regulation of behavior GO:0048520 38 0.105
regulation of defense response GO:0031347 68 0.105
response to gamma radiation GO:0010332 24 0.103
cation homeostasis GO:0055080 195 0.102
lymphocyte migration GO:0072676 3 0.102
positive regulation of cellular component movement GO:0051272 102 0.102
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.101
cardiovascular system development GO:0072358 134 0.101
regulation of neutrophil chemotaxis GO:0090022 5 0.101
positive regulation of leukocyte differentiation GO:1902107 13 0.101
regulation of lymphocyte migration GO:2000401 1 0.101
eosinophil chemotaxis GO:0048245 3 0.100
regulation of neutrophil migration GO:1902622 6 0.100
metal ion homeostasis GO:0055065 186 0.099
positive regulation of mast cell chemotaxis GO:0060754 1 0.099
positive regulation of long term synaptic potentiation GO:1900273 4 0.098
anatomical structure morphogenesis GO:0009653 298 0.097
cellular response to iron iii ion GO:0071283 3 0.097
organ regeneration GO:0031100 101 0.097
response to transforming growth factor beta GO:0071559 46 0.096
response to ionizing radiation GO:0010212 59 0.096
response to lipoteichoic acid GO:0070391 1 0.096
lipid biosynthetic process GO:0008610 128 0.095
cellular metal ion homeostasis GO:0006875 172 0.095
negative regulation of cellular metabolic process GO:0031324 281 0.094
regulation of locomotion GO:0040012 148 0.094
programmed cell death GO:0012501 392 0.094
regulation of nf kappab import into nucleus GO:0042345 5 0.093
hormone metabolic process GO:0042445 69 0.091
positive regulation of developmental process GO:0051094 283 0.089
regulation of metal ion transport GO:0010959 118 0.089
developmental process involved in reproduction GO:0003006 159 0.089
t helper 1 type immune response GO:0042088 1 0.089
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.089
response to interferon gamma GO:0034341 20 0.088
taxis GO:0042330 67 0.088
eosinophil migration GO:0072677 3 0.088
regulation of response to wounding GO:1903034 69 0.086
leukocyte differentiation GO:0002521 30 0.086
cation transport GO:0006812 382 0.086
response to amphetamine GO:0001975 25 0.086
response to toxic substance GO:0009636 133 0.086
response to acid chemical GO:0001101 222 0.086
small molecule biosynthetic process GO:0044283 124 0.085
organic acid metabolic process GO:0006082 292 0.085
regulation of cell proliferation GO:0042127 359 0.084
positive regulation of nf kappab import into nucleus GO:0042346 2 0.084
positive regulation of inflammatory response GO:0050729 24 0.083
response to mineralocorticoid GO:0051385 49 0.083
cellular response to hormone stimulus GO:0032870 247 0.083
cellular response to lipid GO:0071396 201 0.083
acute inflammatory response GO:0002526 58 0.082
t cell migration GO:0072678 2 0.081
cytokine biosynthetic process GO:0042089 3 0.080
negative regulation of metabolic process GO:0009892 331 0.080
regulation of cellular localization GO:0060341 263 0.080
positive regulation of interleukin 1 alpha production GO:0032730 1 0.079
response to vitamin k GO:0032571 4 0.078
response to metal ion GO:0010038 253 0.077
blood circulation GO:0008015 183 0.076
positive regulation of cell development GO:0010720 176 0.076
regulation of cellular protein metabolic process GO:0032268 267 0.076
protein localization GO:0008104 191 0.076
ion homeostasis GO:0050801 212 0.076
positive regulation of neuron projection development GO:0010976 99 0.076
response to growth factor GO:0070848 189 0.075
oxidation reduction process GO:0055114 304 0.075
single organism carbohydrate metabolic process GO:0044723 118 0.075
single organism intracellular transport GO:1902582 166 0.074
response to virus GO:0009615 17 0.073
muscle contraction GO:0006936 88 0.073
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.073
regulation of potassium ion transport GO:0043266 29 0.072
reproduction GO:0000003 245 0.072
regulation of phosphorylation GO:0042325 248 0.072
regulation of mast cell chemotaxis GO:0060753 1 0.072
regulation of immunoglobulin production GO:0002637 4 0.072
cellular component assembly GO:0022607 360 0.071
regulation of interleukin 1 biosynthetic process GO:0045360 1 0.071
protein secretion GO:0009306 34 0.071
response to indole 3 methanol GO:0071680 2 0.070
positive regulation of synaptic plasticity GO:0031915 3 0.070
erk1 and erk2 cascade GO:0070371 48 0.069
neuron development GO:0048666 286 0.069
negative regulation of cytokine production GO:0001818 16 0.068
cellular response to organonitrogen compound GO:0071417 197 0.068
positive regulation of fat cell differentiation GO:0045600 2 0.068
second messenger mediated signaling GO:0019932 51 0.068
positive regulation of phosphorus metabolic process GO:0010562 262 0.067
regulation of transferase activity GO:0051338 123 0.067
positive regulation of t cell chemotaxis GO:0010820 1 0.067
regulation of cellular component organization GO:0051128 368 0.066
heat generation GO:0031649 11 0.066
cellular amino acid metabolic process GO:0006520 107 0.066
reactive oxygen species metabolic process GO:0072593 37 0.066
g protein coupled receptor signaling pathway GO:0007186 242 0.065
secretion GO:0046903 307 0.065
carboxylic acid biosynthetic process GO:0046394 83 0.065
vasculature development GO:0001944 70 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
development of primary sexual characteristics GO:0045137 107 0.065
anion transport GO:0006820 178 0.064
cellular response to alcohol GO:0097306 87 0.063
response to amine GO:0014075 46 0.063
maternal process involved in female pregnancy GO:0060135 38 0.063
multicellular organism reproduction GO:0032504 233 0.063
regulation of ossification GO:0030278 32 0.062
regulation of molecular function GO:0065009 398 0.062
protein complex subunit organization GO:0071822 302 0.062
organophosphate metabolic process GO:0019637 370 0.062
cellular chemical homeostasis GO:0055082 247 0.062
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.062
cell type specific apoptotic process GO:0097285 134 0.062
regulation of jak stat cascade GO:0046425 21 0.061
regulation of interferon gamma production GO:0032649 3 0.061
protein homooligomerization GO:0051260 91 0.061
monosaccharide metabolic process GO:0005996 61 0.061
amine metabolic process GO:0009308 38 0.060
positive regulation of programmed cell death GO:0043068 157 0.060
positive regulation of rna biosynthetic process GO:1902680 197 0.060
regulation of rna biosynthetic process GO:2001141 381 0.060
regulation of system process GO:0044057 208 0.060
positive regulation of protein transport GO:0051222 41 0.060
negative regulation of angiogenesis GO:0016525 10 0.060
regulation of nervous system development GO:0051960 264 0.060
response to heat GO:0009408 60 0.059
lymphocyte activation GO:0046649 43 0.059
macromolecule localization GO:0033036 252 0.058
positive regulation of ion transport GO:0043270 94 0.058
positive regulation of angiogenesis GO:0045766 28 0.058
positive regulation of defense response GO:0031349 37 0.057
sex differentiation GO:0007548 113 0.057
regulation of cytokine secretion GO:0050707 11 0.057
regulation of blood pressure GO:0008217 83 0.057
regulation of blood vessel size GO:0050880 89 0.056
regulation of myeloid cell differentiation GO:0045637 12 0.056
hormone secretion GO:0046879 115 0.056
kidney vasculature development GO:0061440 6 0.056
transcription from rna polymerase ii promoter GO:0006366 252 0.055
cellular response to ethanol GO:0071361 13 0.055
nucleic acid templated transcription GO:0097659 379 0.054
signal release GO:0023061 145 0.054
leukocyte cell cell adhesion GO:0007159 4 0.054
regulation of reactive oxygen species metabolic process GO:2000377 26 0.054
cellular response to mechanical stimulus GO:0071260 48 0.054
regulation of mononuclear cell proliferation GO:0032944 26 0.053
response to activity GO:0014823 73 0.053
neuron apoptotic process GO:0051402 88 0.053
regulation of acute inflammatory response GO:0002673 23 0.053
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.053
positive regulation of phosphate metabolic process GO:0045937 262 0.053
t cell proliferation GO:0042098 19 0.052
regulation of protein transport GO:0051223 68 0.052
regulation of heat generation GO:0031650 8 0.052
sodium ion transport GO:0006814 82 0.052
vitamin d metabolic process GO:0042359 4 0.052
protein transport GO:0015031 132 0.052
regulation of rna metabolic process GO:0051252 391 0.051
positive regulation of cytokine biosynthetic process GO:0042108 1 0.051
multicellular organismal reproductive process GO:0048609 233 0.051
interleukin 18 production GO:0032621 1 0.051
ovulation cycle process GO:0022602 50 0.050
regulation of cell cycle GO:0051726 73 0.050
transformation of host cell by virus GO:0019087 4 0.050
positive regulation of homeostatic process GO:0032846 49 0.049
negative regulation of biosynthetic process GO:0009890 168 0.049
chemical homeostasis GO:0048878 292 0.048
regulation of neuron differentiation GO:0045664 208 0.047
vascular process in circulatory system GO:0003018 96 0.047
neuron differentiation GO:0030182 368 0.047
response to axon injury GO:0048678 59 0.047
carbohydrate derivative metabolic process GO:1901135 346 0.047
hormone transport GO:0009914 121 0.047
cellular response to drug GO:0035690 30 0.047
blood vessel morphogenesis GO:0048514 58 0.046
cellular response to corticosteroid stimulus GO:0071384 69 0.046
response to alkaloid GO:0043279 132 0.046
jak stat cascade GO:0007259 26 0.046
positive regulation of interferon gamma production GO:0032729 2 0.046
positive regulation of cytokine secretion GO:0050715 9 0.046
cytokine secretion GO:0050663 15 0.046
response to glucose GO:0009749 136 0.046
multicellular organismal catabolic process GO:0044243 2 0.046
female sex differentiation GO:0046660 59 0.045
immune system development GO:0002520 41 0.044
positive regulation of lymphocyte proliferation GO:0050671 20 0.044
regulation of anatomical structure size GO:0090066 135 0.044
positive regulation of protein phosphorylation GO:0001934 135 0.044
ossification GO:0001503 70 0.044
single organism catabolic process GO:0044712 283 0.044
cell projection organization GO:0030030 302 0.044
positive regulation of keratinocyte migration GO:0051549 2 0.044
regulation of chronic inflammatory response GO:0002676 3 0.044
proteolysis GO:0006508 175 0.043
cellular homeostasis GO:0019725 252 0.043
positive regulation of protein kinase b signaling GO:0051897 10 0.043
cellular response to extracellular stimulus GO:0031668 73 0.043
negative regulation of cellular carbohydrate metabolic process GO:0010677 7 0.043
positive regulation of jak stat cascade GO:0046427 19 0.043
glucose metabolic process GO:0006006 52 0.043
gland development GO:0048732 155 0.043
immunoglobulin secretion GO:0048305 1 0.043
sensory perception of pain GO:0019233 73 0.043
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.042
gonad development GO:0008406 104 0.042
negative regulation of rna metabolic process GO:0051253 123 0.042
cellular response to oxidative stress GO:0034599 76 0.042
response to cold GO:0009409 29 0.041
regulation of cell activation GO:0050865 50 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
regulation of interleukin 1 alpha biosynthetic process GO:0050721 1 0.041
regulation of renin secretion into blood stream GO:1900133 1 0.040
vitamin biosynthetic process GO:0009110 3 0.040
negative regulation of programmed cell death GO:0043069 183 0.040
neuron projection development GO:0031175 273 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
cell cell signaling GO:0007267 335 0.039
pseudopodium assembly GO:0031269 3 0.039
growth GO:0040007 165 0.039
rhythmic process GO:0048511 156 0.039
ovulation GO:0030728 17 0.039
development of primary female sexual characteristics GO:0046545 56 0.038
cellular response to nutrient levels GO:0031669 60 0.038
placenta development GO:0001890 22 0.038
positive regulation of cellular protein metabolic process GO:0032270 167 0.038
divalent inorganic cation transport GO:0072511 134 0.038
cellular response to ketone GO:1901655 51 0.038
positive regulation of molecular function GO:0044093 230 0.038
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.038
response to corticosterone GO:0051412 40 0.038
regulation of cell projection organization GO:0031344 175 0.038
single organism cell adhesion GO:0098602 46 0.037
regulation of stress activated mapk cascade GO:0032872 23 0.037
regulation of lipid biosynthetic process GO:0046890 38 0.037
response to nicotine GO:0035094 51 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
synaptic growth at neuromuscular junction GO:0051124 1 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
regulation of cellular response to stress GO:0080135 49 0.037
prostaglandin metabolic process GO:0006693 12 0.037
macromolecular complex assembly GO:0065003 273 0.036
negative regulation of immune response to tumor cell GO:0002838 2 0.036
helper t cell diapedesis GO:0035685 1 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
regulation of kinase activity GO:0043549 117 0.036
positive regulation of catalytic activity GO:0043085 184 0.036
positive regulation of response to wounding GO:1903036 34 0.036
catabolic process GO:0009056 351 0.036
nitrogen compound transport GO:0071705 229 0.036
glycerolipid metabolic process GO:0046486 67 0.036
positive regulation of nervous system development GO:0051962 178 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
alcohol metabolic process GO:0006066 77 0.036
inflammatory response to antigenic stimulus GO:0002437 18 0.035
regulation of erk1 and erk2 cascade GO:0070372 41 0.035
regulation of neurogenesis GO:0050767 247 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
prostate gland epithelium morphogenesis GO:0060740 2 0.035
negative regulation of gene expression GO:0010629 199 0.034
platelet derived growth factor production GO:0090360 2 0.034
positive regulation of intracellular transport GO:0032388 39 0.034
cellular component biogenesis GO:0044085 368 0.034
rna metabolic process GO:0016070 406 0.034
organic hydroxy compound metabolic process GO:1901615 115 0.034
immune effector process GO:0002252 53 0.034
cellular response to metal ion GO:0071248 55 0.034
sequestering of metal ion GO:0051238 9 0.034
pseudopodium organization GO:0031268 3 0.033
cellular ketone metabolic process GO:0042180 51 0.033

Il6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org