Rattus norvegicus

78 known processes

Il6st

interleukin 6 signal transducer

(Aliases: Il-6rb,Gp130,Ac1055)

Il6st biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.314
Zebrafish Rat
regulation of cell proliferation GO:0042127 359 0.289
Human Mouse
cellular response to cytokine stimulus GO:0071345 127 0.284
positive regulation of transcription dna templated GO:0045893 197 0.282
response to other organism GO:0051707 220 0.267
response to molecule of bacterial origin GO:0002237 194 0.244
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.206
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.194
negative regulation of multicellular organismal process GO:0051241 203 0.185
positive regulation of cell communication GO:0010647 271 0.173
Human
cellular response to hormone stimulus GO:0032870 247 0.169
cellular component biogenesis GO:0044085 368 0.161
negative regulation of metabolic process GO:0009892 331 0.144
positive regulation of rna metabolic process GO:0051254 203 0.142
reproductive process GO:0022414 372 0.141
cellular component movement GO:0006928 248 0.141
cell migration GO:0016477 197 0.133
positive regulation of phosphate metabolic process GO:0045937 262 0.133
Human
response to lipopolysaccharide GO:0032496 191 0.132
positive regulation of gene expression GO:0010628 244 0.132
rna metabolic process GO:0016070 406 0.129
positive regulation of nucleic acid templated transcription GO:1903508 197 0.127
neuron projection development GO:0031175 273 0.125
Zebrafish Rat
circulatory system process GO:0003013 183 0.122
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.121
regulation of catalytic activity GO:0050790 304 0.119
cellular response to oxygen containing compound GO:1901701 386 0.119
oxoacid metabolic process GO:0043436 290 0.118
single organism biosynthetic process GO:0044711 342 0.117
blood circulation GO:0008015 183 0.117
response to estradiol GO:0032355 164 0.116
carboxylic acid metabolic process GO:0019752 289 0.114
lymphocyte activation GO:0046649 43 0.112
Human
jak stat cascade GO:0007259 26 0.109
Human
cation transport GO:0006812 382 0.109
programmed cell death GO:0012501 392 0.108
Rat
response to wounding GO:0009611 254 0.107
Zebrafish
regulation of cellular protein metabolic process GO:0032268 267 0.106
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.104
neuron development GO:0048666 286 0.100
Zebrafish Rat
neuron death GO:0070997 127 0.100
cellular amine metabolic process GO:0044106 38 0.100
hepaticobiliary system development GO:0061008 90 0.097
immune system process GO:0002376 204 0.096
Human
regulation of neurogenesis GO:0050767 247 0.096
Zebrafish Mouse
regulation of molecular function GO:0065009 398 0.094
response to external biotic stimulus GO:0043207 221 0.094
cellular response to abiotic stimulus GO:0071214 85 0.093
response to extracellular stimulus GO:0009991 380 0.090
regulation of protein metabolic process GO:0051246 289 0.090
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.087
negative regulation of macromolecule metabolic process GO:0010605 260 0.087
renal system development GO:0072001 67 0.085
regulation of metanephros development GO:0072215 4 0.083
secretion GO:0046903 307 0.082
regulation of rna metabolic process GO:0051252 391 0.082
regulation of ion transport GO:0043269 245 0.082
regulation of cell differentiation GO:0045595 320 0.081
Human Zebrafish Mouse
positive regulation of signal transduction GO:0009967 175 0.080
Human
cellular response to lipid GO:0071396 201 0.079
organ morphogenesis GO:0009887 75 0.079
Rat
response to corticosteroid GO:0031960 235 0.079
reproduction GO:0000003 245 0.078
homeostatic process GO:0042592 331 0.078
hair cell differentiation GO:0035315 2 0.077
positive regulation of immune system process GO:0002684 90 0.077
Human
cell activation GO:0001775 97 0.077
Human
negative regulation of molecular function GO:0044092 133 0.076
cellular amino acid metabolic process GO:0006520 107 0.072
negative regulation of cell death GO:0060548 229 0.071
Rat
transmembrane transport GO:0055085 412 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.069
positive regulation of signaling GO:0023056 270 0.069
Human
regulation of protein modification process GO:0031399 194 0.069
Human
positive regulation of cytoplasmic transport GO:1903651 32 0.068
protein localization GO:0008104 191 0.068
tissue development GO:0009888 252 0.068
regulation of protein phosphorylation GO:0001932 183 0.068
Human
intracellular signal transduction GO:0035556 314 0.068
Human
eye morphogenesis GO:0048592 4 0.068
response to mechanical stimulus GO:0009612 134 0.067
positive regulation of cellular biosynthetic process GO:0031328 295 0.066
cellular response to molecule of bacterial origin GO:0071219 56 0.066
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.065
Human
regulation of system process GO:0044057 208 0.064
response to biotic stimulus GO:0009607 226 0.064
regulation of transcription dna templated GO:0006355 374 0.064
positive regulation of rna biosynthetic process GO:1902680 197 0.063
negative regulation of gene expression GO:0010629 199 0.062
regulation of cellular component organization GO:0051128 368 0.062
Zebrafish
cellular response to peptide hormone stimulus GO:0071375 120 0.062
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.061
organic acid metabolic process GO:0006082 292 0.060
regulation of cellular component movement GO:0051270 150 0.060
development of primary sexual characteristics GO:0045137 107 0.060
response to estrogen GO:0043627 232 0.060
response to inorganic substance GO:0010035 377 0.059
nucleic acid templated transcription GO:0097659 379 0.059
kidney mesenchyme development GO:0072074 2 0.059
inflammatory response GO:0006954 150 0.059
ion transmembrane transport GO:0034220 365 0.059
vesicle mediated transport GO:0016192 181 0.058
regulation of nucleic acid templated transcription GO:1903506 380 0.058
negative regulation of kidney development GO:0090185 2 0.058
liver development GO:0001889 90 0.057
cellular response to stress GO:0033554 269 0.056
Zebrafish
response to peptide GO:1901652 292 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.056
regulation of programmed cell death GO:0043067 341 0.056
Rat
signal transduction by phosphorylation GO:0023014 144 0.055
regulation of mapk cascade GO:0043408 116 0.055
regeneration GO:0031099 163 0.055
Zebrafish Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.054
cell morphogenesis GO:0000902 142 0.054
Rat
cellular component assembly GO:0022607 360 0.053
single organism reproductive process GO:0044702 297 0.053
rhythmic process GO:0048511 156 0.053
head development GO:0060322 247 0.053
nitrogen compound transport GO:0071705 229 0.052
rna biosynthetic process GO:0032774 380 0.052
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.052
organophosphate metabolic process GO:0019637 370 0.052
cell morphogenesis involved in differentiation GO:0000904 119 0.051
mesenchymal cell proliferation GO:0010463 4 0.051
negative regulation of programmed cell death GO:0043069 183 0.050
Rat
regulation of cell activation GO:0050865 50 0.050
Human
catabolic process GO:0009056 351 0.050
positive regulation of biosynthetic process GO:0009891 319 0.050
heart morphogenesis GO:0003007 3 0.049
cellular response to endogenous stimulus GO:0071495 377 0.049
multi organism reproductive process GO:0044703 262 0.049
carbohydrate derivative biosynthetic process GO:1901137 124 0.049
regulation of immune system process GO:0002682 123 0.049
Human
transcription dna templated GO:0006351 377 0.049
positive regulation of response to stimulus GO:0048584 285 0.049
Human Zebrafish
positive regulation of transport GO:0051050 245 0.048
taxis GO:0042330 67 0.048
growth GO:0040007 165 0.048
response to nutrient levels GO:0031667 370 0.048
regulation of rna biosynthetic process GO:2001141 381 0.047
cellular response to peptide GO:1901653 133 0.047
regulation of multicellular organismal development GO:2000026 376 0.047
Zebrafish Mouse
protein phosphorylation GO:0006468 345 0.047
Human
lipid metabolic process GO:0006629 283 0.046
regulation of phosphate metabolic process GO:0019220 349 0.046
Human
cell projection morphogenesis GO:0048858 123 0.045
Rat
localization of cell GO:0051674 202 0.045
b cell differentiation GO:0030183 2 0.045
epithelial cell differentiation GO:0030855 71 0.045
response to glucocorticoid GO:0051384 223 0.044
heart contraction GO:0060047 57 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.044
cognition GO:0050890 92 0.044
regulation of nervous system development GO:0051960 264 0.043
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.043
muscle contraction GO:0006936 88 0.043
regulation of neuron projection development GO:0010975 161 0.043
Zebrafish
positive regulation of response to external stimulus GO:0032103 51 0.043
Zebrafish
cardiovascular system development GO:0072358 134 0.042
organic substance catabolic process GO:1901575 316 0.042
protein complex biogenesis GO:0070271 263 0.042
amine metabolic process GO:0009308 38 0.042
metanephric renal vesicle morphogenesis GO:0072283 3 0.042
cellular response to external stimulus GO:0071496 118 0.041
regulation of apoptotic process GO:0042981 335 0.041
Rat
cellular ketone metabolic process GO:0042180 51 0.041
negative regulation of metanephros development GO:0072217 2 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
Human
regulation of cell development GO:0060284 263 0.040
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.040
small molecule biosynthetic process GO:0044283 124 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.039
regulation of protein kinase activity GO:0045859 105 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
cardiac muscle cell contraction GO:0086003 10 0.039
organophosphate biosynthetic process GO:0090407 143 0.038
cell part morphogenesis GO:0032990 123 0.038
Rat
kidney development GO:0001822 67 0.038
negative regulation of biosynthetic process GO:0009890 168 0.038
response to bacterium GO:0009617 200 0.038
positive regulation of cell differentiation GO:0045597 217 0.038
Human Zebrafish Mouse
negative regulation of developmental process GO:0051093 125 0.037
central nervous system development GO:0007417 311 0.037
Mouse
ribose phosphate biosynthetic process GO:0046390 87 0.037
positive regulation of molecular function GO:0044093 230 0.037
protein complex assembly GO:0006461 263 0.037
negative regulation of cellular biosynthetic process GO:0031327 161 0.037
response to decreased oxygen levels GO:0036293 237 0.037
heart process GO:0003015 57 0.036
regulation of signal transduction GO:0009966 318 0.036
Human Mouse
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.036
Human Rat
female sex differentiation GO:0046660 59 0.036
purine ribonucleotide biosynthetic process GO:0009152 81 0.036
aging GO:0007568 241 0.036
regulation of phosphorylation GO:0042325 248 0.035
Human
cellular response to nitrogen compound GO:1901699 210 0.035
response to ketone GO:1901654 182 0.035
cellular catabolic process GO:0044248 295 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
Zebrafish
mapk cascade GO:0000165 140 0.034
anion transport GO:0006820 178 0.034
positive regulation of cellular amine metabolic process GO:0033240 3 0.034
ovulation cycle process GO:0022602 50 0.034
gonad development GO:0008406 104 0.034
endocytosis GO:0006897 84 0.033
regulation of heart contraction GO:0008016 48 0.033
regulation of hydrogen peroxide biosynthetic process GO:0010728 2 0.033
cellular response to growth factor stimulus GO:0071363 162 0.033
response to insulin GO:0032868 133 0.033
cytosolic calcium ion homeostasis GO:0051480 140 0.033
reproductive system development GO:0061458 128 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
Human
macromolecule localization GO:0033036 252 0.033
development of primary female sexual characteristics GO:0046545 56 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
nucleoside phosphate biosynthetic process GO:1901293 102 0.032
intracellular receptor signaling pathway GO:0030522 35 0.032
cellular response to lipopolysaccharide GO:0071222 55 0.032
sex differentiation GO:0007548 113 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.032
circulatory system development GO:0072359 134 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
regulation of cell migration GO:0030334 128 0.032
cell projection organization GO:0030030 302 0.031
Zebrafish Rat
mechanoreceptor differentiation GO:0042490 2 0.031
t cell activation GO:0042110 29 0.031
Human
regulation of response to external stimulus GO:0032101 106 0.031
Zebrafish
developmental process involved in reproduction GO:0003006 159 0.031
cellular response to organonitrogen compound GO:0071417 197 0.031
regulation of neuron differentiation GO:0045664 208 0.030
Zebrafish
regulation of catabolic process GO:0009894 113 0.030
intracellular transport GO:0046907 185 0.030
multicellular organism reproduction GO:0032504 233 0.030
response to nutrient GO:0007584 248 0.030
cellular calcium ion homeostasis GO:0006874 160 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
cellular response to interleukin 6 GO:0071354 9 0.029
sexual reproduction GO:0019953 148 0.029
regulation of body fluid levels GO:0050878 90 0.029
apoptotic process GO:0006915 381 0.029
Rat
neuron projection morphogenesis GO:0048812 122 0.029
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.029
regulation of mesenchymal cell proliferation GO:0010464 4 0.028
brain development GO:0007420 247 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.028
regulation of response to wounding GO:1903034 69 0.028
Zebrafish
regulation of blood circulation GO:1903522 110 0.028
purine containing compound metabolic process GO:0072521 253 0.028
female gonad development GO:0008585 53 0.028
response to oxidative stress GO:0006979 186 0.028
purine nucleotide biosynthetic process GO:0006164 83 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
Human
regulation of kinase activity GO:0043549 117 0.028
negative regulation of neurogenesis GO:0050768 78 0.027
cellular homeostasis GO:0019725 252 0.027
regulation of hormone levels GO:0010817 187 0.027
regulation of cell projection organization GO:0031344 175 0.027
Zebrafish
cation transmembrane transport GO:0098655 263 0.027
actin mediated cell contraction GO:0070252 12 0.027
embryonic skeletal system development GO:0048706 3 0.027
reproductive structure development GO:0048608 128 0.027
gastrulation GO:0007369 2 0.027
chemotaxis GO:0006935 66 0.027
single organism behavior GO:0044708 130 0.027
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.027
response to cytokine GO:0034097 215 0.027
locomotion GO:0040011 237 0.027
regulation of cellular localization GO:0060341 263 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.026
Human
response to growth factor GO:0070848 189 0.026
regulation of canonical wnt signaling pathway GO:0060828 4 0.026
cardiac muscle contraction GO:0060048 27 0.026
motor neuron axon guidance GO:0008045 1 0.026
defense response GO:0006952 194 0.026
peptidyl tyrosine modification GO:0018212 72 0.026
Human
urogenital system development GO:0001655 78 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.026
negative regulation of signaling GO:0023057 157 0.026
Human
cell differentiation involved in kidney development GO:0061005 4 0.026
purine nucleotide metabolic process GO:0006163 229 0.025
response to interleukin 1 GO:0070555 55 0.025
behavior GO:0007610 205 0.025
positive regulation of cell death GO:0010942 184 0.025
endocardial cushion development GO:0003197 1 0.025
regulation of transferase activity GO:0051338 123 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.025
glycosaminoglycan biosynthetic process GO:0006024 4 0.025
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
Rat
regulation of secretion GO:0051046 224 0.024
establishment of tissue polarity GO:0007164 2 0.024
purine containing compound biosynthetic process GO:0072522 85 0.024
secretion by cell GO:0032940 248 0.024
regulation of transmembrane transport GO:0034762 122 0.024
negative regulation of neuron death GO:1901215 69 0.024
carbohydrate metabolic process GO:0005975 130 0.024
Mouse
gland development GO:0048732 155 0.023
positive regulation of intracellular transport GO:0032388 39 0.023
ion homeostasis GO:0050801 212 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
Human
regulation of neuron death GO:1901214 115 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
cellular response to alcohol GO:0097306 87 0.023
positive regulation of lymphocyte activation GO:0051251 25 0.023
Human
mesenchymal to epithelial transition GO:0060231 3 0.023
establishment of planar polarity GO:0001736 1 0.023
positive regulation of lymphocyte proliferation GO:0050671 20 0.023
Human
nucleotide metabolic process GO:0009117 279 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
nucleotide biosynthetic process GO:0009165 98 0.023
regulation of anion transport GO:0044070 43 0.023
proteolysis GO:0006508 175 0.022
regulation of hormone secretion GO:0046883 106 0.022
aminoglycan biosynthetic process GO:0006023 4 0.022
epithelium development GO:0060429 96 0.022
regulation of muscle system process GO:0090257 79 0.022
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
cellular component morphogenesis GO:0032989 155 0.022
Rat
cell growth GO:0016049 104 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
cytoplasmic transport GO:0016482 115 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of lymphocyte activation GO:0051249 34 0.021
Human
positive regulation of cell projection organization GO:0031346 111 0.021
Zebrafish
positive regulation of neurogenesis GO:0050769 165 0.021
Zebrafish Mouse
actin filament based movement GO:0030048 16 0.021
potassium ion transport GO:0006813 97 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
learning or memory GO:0007611 90 0.021
response to camp GO:0051591 91 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
Human
macromolecular complex assembly GO:0065003 273 0.021
positive regulation of peptide secretion GO:0002793 52 0.021
neurological system process GO:0050877 219 0.021
protein complex subunit organization GO:0071822 302 0.021
cell motility GO:0048870 202 0.021
muscle system process GO:0003012 115 0.020
vasculature development GO:0001944 70 0.020
positive regulation of protein modification process GO:0031401 142 0.020
Human
regulation of leukocyte activation GO:0002694 45 0.020
Human
mononuclear cell proliferation GO:0032943 29 0.020
Human
molting cycle process GO:0022404 2 0.020
epithelial cell proliferation GO:0050673 54 0.020
hair cycle process GO:0022405 2 0.020
action potential GO:0001508 54 0.020
metanephric epithelium development GO:0072207 4 0.020
vascular process in circulatory system GO:0003018 96 0.020
cellular response to biotic stimulus GO:0071216 59 0.019
response to hypoxia GO:0001666 231 0.019
organic anion transport GO:0015711 132 0.019
biological adhesion GO:0022610 110 0.019
regulation of cytokine production GO:0001817 56 0.019
hormone transport GO:0009914 121 0.019
positive regulation of hormone secretion GO:0046887 65 0.019
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 2 0.019
immune response GO:0006955 104 0.019
axon development GO:0061564 96 0.019
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
response to peptide hormone GO:0043434 278 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
response to nicotine GO:0035094 51 0.019
purine ribonucleoside biosynthetic process GO:0046129 21 0.019
bmp signaling pathway GO:0030509 4 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
regulation of hydrolase activity GO:0051336 143 0.019
hematopoietic or lymphoid organ development GO:0048534 36 0.019
positive regulation of transferase activity GO:0051347 81 0.019
morphogenesis of a polarized epithelium GO:0001738 1 0.019
protein localization to organelle GO:0033365 57 0.019
positive regulation of nervous system development GO:0051962 178 0.018
Zebrafish Mouse
smooth muscle cell proliferation GO:0048659 77 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
cellular response to ketone GO:1901655 51 0.018
positive regulation of leukocyte proliferation GO:0070665 20 0.018
Human
inner ear receptor cell differentiation GO:0060113 2 0.018
regulation of peptide transport GO:0090087 87 0.018
axonogenesis GO:0007409 71 0.018
regulation of response to stress GO:0080134 126 0.018
Zebrafish
negative regulation of cell communication GO:0010648 158 0.018
Human
positive regulation of developmental process GO:0051094 283 0.018
Human Zebrafish Mouse
cellular response to steroid hormone stimulus GO:0071383 93 0.018
intracellular protein transport GO:0006886 79 0.018
regulation of leukocyte proliferation GO:0070663 26 0.018
Human
positive regulation of endocytosis GO:0045807 28 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
steroid metabolic process GO:0008202 73 0.018
regulation of peptide secretion GO:0002791 82 0.018
protein transport GO:0015031 132 0.018
nephron tubule epithelial cell differentiation GO:0072160 1 0.018
cell substrate adhesion GO:0031589 29 0.018
skeletal system development GO:0001501 41 0.018
regulation of striated muscle contraction GO:0006942 21 0.018
positive regulation of immunoglobulin production GO:0002639 4 0.018
positive regulation of mapk cascade GO:0043410 92 0.017
nucleoside monophosphate biosynthetic process GO:0009124 28 0.017
sequestering of calcium ion GO:0051208 8 0.017
lipid localization GO:0010876 62 0.017
camera type eye morphogenesis GO:0048593 2 0.017
gamete generation GO:0007276 124 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
regulation of blood pressure GO:0008217 83 0.017
regulation of mononuclear cell proliferation GO:0032944 26 0.017
Human
negative regulation of transport GO:0051051 136 0.017
negative regulation of neuron apoptotic process GO:0043524 45 0.017
ossification GO:0001503 70 0.017
Human
negative regulation of cell development GO:0010721 82 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
Human Mouse
single organism intracellular transport GO:1902582 166 0.017
wound healing GO:0042060 122 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of locomotion GO:0040012 148 0.017
cellular response to mechanical stimulus GO:0071260 48 0.017
metanephros morphogenesis GO:0003338 6 0.017
protein targeting GO:0006605 61 0.016
skeletal muscle satellite cell proliferation GO:0014841 1 0.016
digestive tract development GO:0048565 39 0.016
choline transport GO:0015871 4 0.016
regulation of cell motility GO:2000145 131 0.016
regulation of defense response GO:0031347 68 0.016
positive regulation of jak stat cascade GO:0046427 19 0.016
Human
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
Rat
organic acid transport GO:0015849 116 0.016
carboxylic acid transport GO:0046942 115 0.016
ovulation cycle GO:0042698 67 0.016
regulation of cardiac muscle contraction GO:0055117 17 0.016
morphogenesis of an epithelium GO:0002009 20 0.016
peptide biosynthetic process GO:0043043 3 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.016
response to alkaloid GO:0043279 132 0.016
metal ion transport GO:0030001 289 0.016
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 3 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
striated muscle contraction GO:0006941 44 0.016
establishment of protein localization to organelle GO:0072594 44 0.016
response to metal ion GO:0010038 253 0.015
cell adhesion GO:0007155 110 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
Human
organic hydroxy compound transport GO:0015850 77 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
Human Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.015
memory GO:0007613 54 0.015
gliogenesis GO:0042063 93 0.015
Mouse
maintenance of location GO:0051235 17 0.015
regulation of nucleotide biosynthetic process GO:0030808 47 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
eye development GO:0001654 50 0.015
positive regulation of cytokine production GO:0001819 42 0.015
cell type specific apoptotic process GO:0097285 134 0.015
Rat
response to vitamin GO:0033273 131 0.015
negative regulation of signal transduction GO:0009968 83 0.015
Human
positive regulation of leukocyte activation GO:0002696 30 0.015
Human
response to carbohydrate GO:0009743 183 0.015
actin filament based process GO:0030029 86 0.015
regulation of intracellular transport GO:0032386 65 0.015
stem cell maintenance GO:0019827 6 0.015
positive regulation of necrotic cell death GO:0010940 4 0.015
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation GO:1902728 1 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
nuclear transport GO:0051169 49 0.015
circadian rhythm GO:0007623 88 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
programmed necrotic cell death GO:0097300 2 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
immune system development GO:0002520 41 0.014
regulation of growth GO:0040008 105 0.014
positive regulation of kinase activity GO:0033674 77 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
leukocyte migration GO:0050900 38 0.014
response to glucose GO:0009749 136 0.014
lipid biosynthetic process GO:0008610 128 0.014
chemical homeostasis GO:0048878 292 0.014
vasodilation GO:0042311 44 0.014
embryonic cranial skeleton morphogenesis GO:0048701 2 0.014
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of cell growth GO:0001558 85 0.014
positive regulation of cell activation GO:0050867 34 0.014
Human
metanephric tubule development GO:0072170 4 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
cytokine mediated signaling pathway GO:0019221 43 0.014
response to interleukin 13 GO:0035962 3 0.014

Il6st disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016