Rattus norvegicus

53 known processes

Impa1

Inositol (myo)-1(or 4)-monophosphatase 1

Impa1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell death GO:0060548 229 0.146
chlorinated hydrocarbon metabolic process GO:0042196 4 0.134
intracellular signal transduction GO:0035556 314 0.123
rna metabolic process GO:0016070 406 0.111
rna biosynthetic process GO:0032774 380 0.108
anterograde axon cargo transport GO:0008089 1 0.105
apoptotic process GO:0006915 381 0.089
regulation of rna metabolic process GO:0051252 391 0.085
protein phosphorylation GO:0006468 345 0.081
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.078
transcription dna templated GO:0006351 377 0.078
intracellular transport GO:0046907 185 0.071
positive regulation of phosphorus metabolic process GO:0010562 262 0.067
regulation of bmp signaling pathway GO:0030510 2 0.065
regulation of cell differentiation GO:0045595 320 0.063
protein localization GO:0008104 191 0.061
organelle organization GO:0006996 266 0.061
mapk cascade GO:0000165 140 0.059
regulation of programmed cell death GO:0043067 341 0.058
regulation of phosphate metabolic process GO:0019220 349 0.057
organophosphate biosynthetic process GO:0090407 143 0.056
negative regulation of apoptotic process GO:0043066 181 0.054
regulation of multicellular organismal development GO:2000026 376 0.054
vesicle mediated transport GO:0016192 181 0.053
nucleotide metabolic process GO:0009117 279 0.051
secretion GO:0046903 307 0.050
negative regulation of response to stimulus GO:0048585 155 0.050
ribonucleoside triphosphate metabolic process GO:0009199 141 0.049
protein transport GO:0015031 132 0.049
programmed cell death GO:0012501 392 0.048
negative regulation of rna metabolic process GO:0051253 123 0.047
cell cell signaling GO:0007267 335 0.046
purine containing compound metabolic process GO:0072521 253 0.046
regulation of signal transduction GO:0009966 318 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
protein localization to organelle GO:0033365 57 0.045
establishment of protein localization GO:0045184 141 0.044
secretion by cell GO:0032940 248 0.042
purine ribonucleotide catabolic process GO:0009154 136 0.042
protein complex biogenesis GO:0070271 263 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
cellular response to growth factor stimulus GO:0071363 162 0.039
negative regulation of programmed cell death GO:0043069 183 0.038
regulation of rna biosynthetic process GO:2001141 381 0.037
macromolecule localization GO:0033036 252 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
regulation of apoptotic process GO:0042981 335 0.036
single organism intracellular transport GO:1902582 166 0.035
organophosphate metabolic process GO:0019637 370 0.035
cellular component biogenesis GO:0044085 368 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
positive regulation of neurogenesis GO:0050769 165 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
single organism biosynthetic process GO:0044711 342 0.034
positive regulation of response to stimulus GO:0048584 285 0.034
regulation of protein modification process GO:0031399 194 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.032
organelle localization GO:0051640 55 0.032
synaptic transmission GO:0007268 235 0.032
locomotion GO:0040011 237 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
positive regulation of nervous system development GO:0051962 178 0.030
organophosphate catabolic process GO:0046434 148 0.030
negative regulation of signaling GO:0023057 157 0.030
cell adhesion GO:0007155 110 0.030
regulated secretory pathway GO:0045055 17 0.030
positive regulation of protein modification process GO:0031401 142 0.030
developmental growth GO:0048589 100 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
response to growth factor GO:0070848 189 0.029
neuromuscular synaptic transmission GO:0007274 2 0.029
response to nutrient levels GO:0031667 370 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.028
regulation of transcription dna templated GO:0006355 374 0.027
nucleic acid templated transcription GO:0097659 379 0.027
cellular response to stress GO:0033554 269 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.027
positive regulation of signaling GO:0023056 270 0.027
regulation of purine nucleotide metabolic process GO:1900542 115 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
positive regulation of cell development GO:0010720 176 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
cellular amine metabolic process GO:0044106 38 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
synaptic vesicle endocytosis GO:0048488 4 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
central nervous system development GO:0007417 311 0.026
reproductive process GO:0022414 372 0.026
regulation of neurogenesis GO:0050767 247 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
positive regulation of locomotion GO:0040017 102 0.025
positive regulation of neuron projection development GO:0010976 99 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
response to estrogen GO:0043627 232 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
response to acid chemical GO:0001101 222 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of phosphorylation GO:0042325 248 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.023
response to inorganic substance GO:0010035 377 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
pigment biosynthetic process GO:0046148 4 0.023
neuron projection morphogenesis GO:0048812 122 0.023
central nervous system neuron axonogenesis GO:0021955 1 0.022
cell motility GO:0048870 202 0.022
regulation of protein metabolic process GO:0051246 289 0.022
nucleoside monophosphate catabolic process GO:0009125 56 0.022
negative regulation of cell communication GO:0010648 158 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.021
embryonic axis specification GO:0000578 1 0.021
negative regulation of metabolic process GO:0009892 331 0.021
response to other organism GO:0051707 220 0.021
positive regulation of molecular function GO:0044093 230 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
embryonic pattern specification GO:0009880 1 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
carbohydrate metabolic process GO:0005975 130 0.021
axon cargo transport GO:0008088 1 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
regulation of cellular component movement GO:0051270 150 0.020
regulation of cell motility GO:2000145 131 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
response to extracellular stimulus GO:0009991 380 0.020
ras protein signal transduction GO:0007265 29 0.020
negative regulation of gene expression GO:0010629 199 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
positive regulation of signal transduction GO:0009967 175 0.019
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
organic hydroxy compound biosynthetic process GO:1901617 51 0.018
nucleotide catabolic process GO:0009166 139 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cell projection morphogenesis GO:0048858 123 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cellular component assembly GO:0022607 360 0.018
postsynaptic density protein 95 clustering GO:0097119 2 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.017
response to metal ion GO:0010038 253 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
organic substance catabolic process GO:1901575 316 0.017
cellular protein localization GO:0034613 122 0.017
cytoplasmic transport GO:0016482 115 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
regulation of cell development GO:0060284 263 0.017
positive regulation of cell communication GO:0010647 271 0.016
lysosomal transport GO:0007041 8 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
bmp signaling pathway GO:0030509 4 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
negative regulation of developmental process GO:0051093 125 0.016
protein complex assembly GO:0006461 263 0.016
purine containing compound catabolic process GO:0072523 138 0.016
macromolecular complex assembly GO:0065003 273 0.016
intracellular protein transport GO:0006886 79 0.016
regulation of cellular component organization GO:0051128 368 0.016
cellular response to external stimulus GO:0071496 118 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
biological adhesion GO:0022610 110 0.015
amine metabolic process GO:0009308 38 0.015
cell projection organization GO:0030030 302 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
cellular macromolecule localization GO:0070727 122 0.015
neuron development GO:0048666 286 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of organelle organization GO:0033043 80 0.015
response to cytokine GO:0034097 215 0.015
phosphatidylcholine biosynthetic process GO:0006656 5 0.015
response to alkaloid GO:0043279 132 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
localization of cell GO:0051674 202 0.014
histone methylation GO:0016571 3 0.014
reproductive system development GO:0061458 128 0.014
regulation of molecular function GO:0065009 398 0.014
synaptic vesicle transport GO:0048489 23 0.014
growth GO:0040007 165 0.014
regulation of cell projection organization GO:0031344 175 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of developmental process GO:0051094 283 0.014
exocytosis GO:0006887 60 0.014
axis specification GO:0009798 4 0.014
synaptic vesicle localization GO:0097479 24 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
response to peptide hormone GO:0043434 278 0.013
mesoderm development GO:0007498 2 0.013
cdp choline pathway GO:0006657 3 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of catabolic process GO:0009894 113 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
cell morphogenesis GO:0000902 142 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
head development GO:0060322 247 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
endocytosis GO:0006897 84 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of axonogenesis GO:0050770 37 0.013
sex differentiation GO:0007548 113 0.013
single organism reproductive process GO:0044702 297 0.012
phototransduction visible light GO:0007603 2 0.012
single organism catabolic process GO:0044712 283 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
ossification GO:0001503 70 0.012
ethanolamine containing compound metabolic process GO:0042439 14 0.012
epithelial cell differentiation GO:0030855 71 0.012
cellular catabolic process GO:0044248 295 0.012
establishment of synaptic vesicle localization GO:0097480 23 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of neuron projection development GO:0010975 161 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
cell migration GO:0016477 197 0.012
chemical homeostasis GO:0048878 292 0.012
establishment of vesicle localization GO:0051650 31 0.012
positive regulation of gene expression GO:0010628 244 0.012
response to amino acid GO:0043200 75 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
small molecule catabolic process GO:0044282 59 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
eye morphogenesis GO:0048592 4 0.011
nucleoside metabolic process GO:0009116 179 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
microtubule based process GO:0007017 36 0.011
neuron differentiation GO:0030182 368 0.011
response to peptide GO:1901652 292 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to external biotic stimulus GO:0043207 221 0.011
positive regulation of cell growth GO:0030307 44 0.010
response to oxidative stress GO:0006979 186 0.010
response to corticosteroid GO:0031960 235 0.010
endosomal transport GO:0016197 14 0.010
stem cell division GO:0017145 4 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
multicellular organismal signaling GO:0035637 44 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
rho protein signal transduction GO:0007266 11 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010

Impa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
central nervous system disease DOID:331 0 0.013
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
carbohydrate metabolic disorder DOID:2978 0 0.010