Rattus norvegicus

156 known processes

Insl3

insulin-like 3

(Aliases: Rlf,MGC112595)

Insl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 297 0.399
response to biotic stimulus GO:0009607 226 0.314
response to nutrient levels GO:0031667 370 0.304
response to other organism GO:0051707 220 0.299
regulation of blood pressure GO:0008217 83 0.267
response to bacterium GO:0009617 200 0.198
regulation of tube size GO:0035150 89 0.152
regulation of anatomical structure size GO:0090066 135 0.130
cellular response to organic cyclic compound GO:0071407 202 0.121
defense response GO:0006952 194 0.110
response to extracellular stimulus GO:0009991 380 0.102
cell cell signaling GO:0007267 335 0.087
development of primary sexual characteristics GO:0045137 107 0.086
cation transport GO:0006812 382 0.086
intracellular signal transduction GO:0035556 314 0.085
blood circulation GO:0008015 183 0.084
negative regulation of cell proliferation GO:0008285 119 0.078
behavior GO:0007610 205 0.075
aging GO:0007568 241 0.074
circulatory system process GO:0003013 183 0.073
multicellular organism reproduction GO:0032504 233 0.070
regulation of blood vessel size GO:0050880 89 0.069
reproduction GO:0000003 245 0.068
response to external biotic stimulus GO:0043207 221 0.066
positive regulation of cell migration GO:0030335 96 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.062
cellular response to endogenous stimulus GO:0071495 377 0.062
response to carbohydrate GO:0009743 183 0.061
response to insulin GO:0032868 133 0.059
transmission of nerve impulse GO:0019226 42 0.058
regulation of cellular component movement GO:0051270 150 0.058
response to acid chemical GO:0001101 222 0.058
neurological system process GO:0050877 219 0.057
response to vitamin GO:0033273 131 0.056
positive regulation of cell communication GO:0010647 271 0.056
metal ion transport GO:0030001 289 0.054
positive regulation of multicellular organismal process GO:0051240 387 0.053
action potential GO:0001508 54 0.052
regulation of blood circulation GO:1903522 110 0.052
programmed cell death GO:0012501 392 0.052
negative regulation of cellular metabolic process GO:0031324 281 0.051
regulation of transferase activity GO:0051338 123 0.048
multi organism reproductive process GO:0044703 262 0.047
response to peptide GO:1901652 292 0.047
response to oxygen levels GO:0070482 265 0.046
cell projection organization GO:0030030 302 0.046
regulation of hormone secretion GO:0046883 106 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
female pregnancy GO:0007565 122 0.044
multicellular organismal reproductive process GO:0048609 233 0.044
positive regulation of molecular function GO:0044093 230 0.043
neuronal action potential GO:0019228 35 0.043
gland development GO:0048732 155 0.043
regulation of cell proliferation GO:0042127 359 0.043
nitrogen compound transport GO:0071705 229 0.042
negative regulation of metabolic process GO:0009892 331 0.042
cellular response to stress GO:0033554 269 0.042
negative regulation of growth GO:0045926 37 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
regulation of mapk cascade GO:0043408 116 0.041
regulation of hormone levels GO:0010817 187 0.041
positive regulation of phosphorylation GO:0042327 177 0.040
cellular ketone metabolic process GO:0042180 51 0.040
positive regulation of biosynthetic process GO:0009891 319 0.040
cellular component biogenesis GO:0044085 368 0.039
cellular response to nutrient levels GO:0031669 60 0.039
regulation of phosphorylation GO:0042325 248 0.039
response to nutrient GO:0007584 248 0.039
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.039
neuron development GO:0048666 286 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
mapk cascade GO:0000165 140 0.038
central nervous system development GO:0007417 311 0.038
nucleic acid templated transcription GO:0097659 379 0.038
reproductive process GO:0022414 372 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
positive regulation of secretion GO:0051047 140 0.037
reproductive structure development GO:0048608 128 0.037
response to hexose GO:0009746 144 0.037
negative regulation of cell death GO:0060548 229 0.036
positive regulation of signaling GO:0023056 270 0.036
sexual reproduction GO:0019953 148 0.036
multi multicellular organism process GO:0044706 138 0.036
regulation of cell migration GO:0030334 128 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.035
response to peptide hormone GO:0043434 278 0.035
regulation of kinase activity GO:0043549 117 0.035
regulation of transcription dna templated GO:0006355 374 0.035
cellular response to ketone GO:1901655 51 0.035
response to vitamin d GO:0033280 34 0.034
vascular process in circulatory system GO:0003018 96 0.034
regulation of cellular component organization GO:0051128 368 0.034
cellular response to growth factor stimulus GO:0071363 162 0.034
reproductive system development GO:0061458 128 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.033
regulation of programmed cell death GO:0043067 341 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
oxidation reduction process GO:0055114 304 0.033
cellular response to alcohol GO:0097306 87 0.033
response to inorganic substance GO:0010035 377 0.033
regulation of response to stress GO:0080134 126 0.033
regulation of molecular function GO:0065009 398 0.032
regulation of anion transport GO:0044070 43 0.032
tissue morphogenesis GO:0048729 22 0.032
apoptotic process GO:0006915 381 0.031
cellular catabolic process GO:0044248 295 0.031
regulation of ion transport GO:0043269 245 0.031
regulation of catalytic activity GO:0050790 304 0.031
secretion GO:0046903 307 0.031
gastrulation GO:0007369 2 0.031
secretion by cell GO:0032940 248 0.031
macromolecular complex assembly GO:0065003 273 0.030
brain development GO:0007420 247 0.030
tissue development GO:0009888 252 0.030
regulation of body fluid levels GO:0050878 90 0.030
hormone transport GO:0009914 121 0.030
response to estrogen GO:0043627 232 0.029
regulation of neurogenesis GO:0050767 247 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
ion transmembrane transport GO:0034220 365 0.028
single organism behavior GO:0044708 130 0.028
cellular component assembly GO:0022607 360 0.027
response to growth factor GO:0070848 189 0.027
signal release GO:0023061 145 0.027
cellular response to external stimulus GO:0071496 118 0.027
positive regulation of transport GO:0051050 245 0.027
positive regulation of developmental process GO:0051094 283 0.027
regulation of locomotion GO:0040012 148 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
forebrain development GO:0030900 98 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
cation transmembrane transport GO:0098655 263 0.026
renal system process GO:0003014 40 0.026
response to cytokine GO:0034097 215 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.025
response to wounding GO:0009611 254 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
dna metabolic process GO:0006259 96 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
rhythmic process GO:0048511 156 0.025
sensory perception GO:0007600 101 0.024
sensory organ development GO:0007423 74 0.024
cell motility GO:0048870 202 0.024
regulation of system process GO:0044057 208 0.024
response to mechanical stimulus GO:0009612 134 0.024
anion transport GO:0006820 178 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
regulation of cellular localization GO:0060341 263 0.024
response to glucose GO:0009749 136 0.024
dicarboxylic acid transport GO:0006835 34 0.023
response to metal ion GO:0010038 253 0.023
positive regulation of epithelial cell proliferation GO:0050679 32 0.023
cellular response to hormone stimulus GO:0032870 247 0.022
regulation of smooth muscle cell proliferation GO:0048660 75 0.022
positive regulation of protein modification process GO:0031401 142 0.022
tube development GO:0035295 89 0.022
neuron projection morphogenesis GO:0048812 122 0.022
regulation of nervous system development GO:0051960 264 0.022
endocrine process GO:0050886 32 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
cardiovascular system development GO:0072358 134 0.022
muscle cell proliferation GO:0033002 84 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.021
cellular response to lipid GO:0071396 201 0.021
response to lipopolysaccharide GO:0032496 191 0.021
regulation of neuron death GO:1901214 115 0.021
multicellular organismal signaling GO:0035637 44 0.021
regulation of membrane potential GO:0042391 110 0.021
catabolic process GO:0009056 351 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
single organism biosynthetic process GO:0044711 342 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
organic substance catabolic process GO:1901575 316 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
circulatory system development GO:0072359 134 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
protein complex biogenesis GO:0070271 263 0.020
behavioral response to nicotine GO:0035095 2 0.020
response to hypoxia GO:0001666 231 0.020
homeostatic process GO:0042592 331 0.020
cellular response to molecule of bacterial origin GO:0071219 56 0.020
head development GO:0060322 247 0.019
ensheathment of neurons GO:0007272 40 0.019
sex differentiation GO:0007548 113 0.019
rna biosynthetic process GO:0032774 380 0.019
positive regulation of transferase activity GO:0051347 81 0.019
organic acid metabolic process GO:0006082 292 0.019
salivary gland development GO:0007431 3 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
response to corticosteroid GO:0031960 235 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
positive regulation of nervous system development GO:0051962 178 0.019
regulation of secretion by cell GO:1903530 208 0.019
regeneration GO:0031099 163 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
organic acid transport GO:0015849 116 0.018
motor neuron axon guidance GO:0008045 1 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
response to estradiol GO:0032355 164 0.018
ion homeostasis GO:0050801 212 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
pallium development GO:0021543 42 0.018
regulation of map kinase activity GO:0043405 53 0.018
regulation of cell projection organization GO:0031344 175 0.018
organic cation transport GO:0015695 11 0.018
heart development GO:0007507 72 0.017
regulation of peptide hormone secretion GO:0090276 80 0.017
response to ketone GO:1901654 182 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
protein phosphorylation GO:0006468 345 0.017
single organism catabolic process GO:0044712 283 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of signal transduction GO:0009966 318 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
regulation of rna metabolic process GO:0051252 391 0.017
protein complex subunit organization GO:0071822 302 0.017
developmental process involved in reproduction GO:0003006 159 0.017
regulation of cell motility GO:2000145 131 0.016
positive regulation of hormone secretion GO:0046887 65 0.016
male sex differentiation GO:0046661 64 0.016
divalent inorganic cation transport GO:0072511 134 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
spermatogenesis GO:0007283 99 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
epithelial cell differentiation GO:0030855 71 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of amine transport GO:0051952 54 0.016
epithelial cell proliferation GO:0050673 54 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.015
regulation of phagocytosis engulfment GO:0060099 4 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
epithelium development GO:0060429 96 0.015
response to monosaccharide GO:0034284 159 0.015
telencephalon development GO:0021537 62 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of amine transport GO:0051953 24 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
multicellular organism growth GO:0035264 1 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
cell part morphogenesis GO:0032990 123 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
cell migration GO:0016477 197 0.015
regulation of smooth muscle cell migration GO:0014910 36 0.015
regulation of protein modification process GO:0031399 194 0.014
regulation of response to external stimulus GO:0032101 106 0.014
organ morphogenesis GO:0009887 75 0.014
cellular macromolecule localization GO:0070727 122 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
rna metabolic process GO:0016070 406 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
gamete generation GO:0007276 124 0.014
regulation of protein metabolic process GO:0051246 289 0.014
peptide transport GO:0015833 97 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
response to chromate GO:0046687 3 0.014
localization of cell GO:0051674 202 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
locomotion GO:0040011 237 0.014
positive regulation of immune system process GO:0002684 90 0.014
synaptic transmission GO:0007268 235 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
vitamin d biosynthetic process GO:0042368 2 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of secretion GO:0051046 224 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of peptide transport GO:0090087 87 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cellular chemical homeostasis GO:0055082 247 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
cellular amine metabolic process GO:0044106 38 0.014
positive regulation of gene expression GO:0010628 244 0.013
neuron death GO:0070997 127 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
positive regulation of tolerance induction GO:0002645 1 0.013
protein complex assembly GO:0006461 263 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
neuron projection development GO:0031175 273 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
protein transport GO:0015031 132 0.013
positive regulation of peptide secretion GO:0002793 52 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of epithelial cell proliferation GO:0050678 49 0.013
proteolysis GO:0006508 175 0.013
vitamin d metabolic process GO:0042359 4 0.013
positive regulation of locomotion GO:0040017 102 0.013
regulation of vasoconstriction GO:0019229 44 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
organic anion transport GO:0015711 132 0.013
vasoconstriction GO:0042310 54 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
amide transport GO:0042886 105 0.013
response to toxic substance GO:0009636 133 0.013
muscle system process GO:0003012 115 0.012
growth GO:0040007 165 0.012
response to progesterone GO:0032570 48 0.012
response to radiation GO:0009314 137 0.012
regulation of behavior GO:0050795 61 0.012
macromolecule catabolic process GO:0009057 58 0.012
regulation of cell differentiation GO:0045595 320 0.012
peptide hormone secretion GO:0030072 84 0.012
negative regulation of gene expression GO:0010629 199 0.012
vitamin biosynthetic process GO:0009110 3 0.012
response to oxidative stress GO:0006979 186 0.012
response to ionizing radiation GO:0010212 59 0.012
choline transport GO:0015871 4 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
phenol containing compound metabolic process GO:0018958 30 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
smooth muscle cell migration GO:0014909 36 0.012
response to vitamin a GO:0033189 36 0.012
t cell tolerance induction GO:0002517 3 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of systemic arterial blood pressure GO:0003073 30 0.012
regulation of cellular component size GO:0032535 51 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.012
positive regulation of blood circulation GO:1903524 65 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
protein oligomerization GO:0051259 191 0.011
axis specification GO:0009798 4 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
peptide secretion GO:0002790 86 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
organophosphate metabolic process GO:0019637 370 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
regulation of organic acid transport GO:0032890 35 0.011
tolerance induction dependent upon immune response GO:0002461 2 0.011
ras protein signal transduction GO:0007265 29 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.011
nucleotide metabolic process GO:0009117 279 0.011
male gamete generation GO:0048232 99 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
antibiotic transport GO:0042891 2 0.011
glucocorticoid metabolic process GO:0008211 7 0.011
memory GO:0007613 54 0.011
aromatic compound catabolic process GO:0019439 168 0.011
cellular homeostasis GO:0019725 252 0.011
neuron differentiation GO:0030182 368 0.011
dna replication GO:0006260 37 0.011
positive regulation of cell development GO:0010720 176 0.010
urinary bladder smooth muscle contraction GO:0014832 4 0.010
gonad development GO:0008406 104 0.010
calcium ion homeostasis GO:0055074 162 0.010
negative regulation of developmental process GO:0051093 125 0.010
positive regulation of kinase activity GO:0033674 77 0.010
eye morphogenesis GO:0048592 4 0.010
regulation of cell growth GO:0001558 85 0.010
negative regulation of cell growth GO:0030308 33 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
associative learning GO:0008306 19 0.010
response to antibiotic GO:0046677 39 0.010
organ regeneration GO:0031100 101 0.010
response to cold GO:0009409 29 0.010
regulation of protein localization GO:0032880 81 0.010
regulation of growth GO:0040008 105 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
regulation of peptide secretion GO:0002791 82 0.010
regulation of blood volume by renal aldosterone GO:0002017 1 0.010
cation homeostasis GO:0055080 195 0.010
cellular response to dexamethasone stimulus GO:0071549 36 0.010
metestrus GO:0060210 1 0.010

Insl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 0 0.023
disease of anatomical entity DOID:7 0 0.023
musculoskeletal system disease DOID:17 0 0.022
nervous system disease DOID:863 0 0.018
connective tissue disease DOID:65 0 0.016
eye disease DOID:5614 0 0.016
eye and adnexa disease DOID:1492 0 0.016
sensory system disease DOID:0050155 0 0.016
kidney disease DOID:557 0 0.015
immune system disease DOID:2914 0 0.014
disease of metabolism DOID:0014667 0 0.014
bone disease DOID:0080001 0 0.011